| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tucidinostat perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Tucidinostat_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GLIS3 | GLIS family zinc finger 3 | 0.0826072 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.082498 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | 0.0806184 |
| IER3 | immediate early response 3 | 0.0647184 |
| HMGA2 | high mobility group AT-hook 2 | 0.0628243 |
| ADM | adrenomedullin | 0.0431967 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0414568 |
| FRMPD4 | FERM and PDZ domain containing 4 | 0.0387863 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0368764 |
| EFNA5 | ephrin-A5 | 0.0357358 |
| SDC4 | syndecan 4 | 0.0342714 |
| PLIN2 | perilipin 2 | 0.0329251 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.031403 |
| INTS6 | integrator complex subunit 6 | 0.030682 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | 0.0300484 |
| SAMD3 | sterile alpha motif domain containing 3 | 0.0291353 |
| TMEM132D | transmembrane protein 132D | 0.0291055 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0281241 |
| AHNAK | AHNAK nucleoprotein | 0.0278141 |
| COL6A2 | collagen, type VI, alpha 2 | 0.0262429 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0262227 |
| FBXO32 | F-box protein 32 | 0.0261316 |
| HDAC9 | histone deacetylase 9 | 0.0246176 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0236794 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0227812 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0225495 |
| PRKG1 | protein kinase, cGMP-dependent, type I | 0.0224737 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0222241 |
| RND3 | Rho family GTPase 3 | 0.0221615 |
| GDF15 | growth differentiation factor 15 | 0.0217396 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0216753 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | 0.0216322 |
| CDH13 | cadherin 13 | 0.0205755 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0204651 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.020238 |
| COL5A1 | collagen, type V, alpha 1 | 0.0200886 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0199249 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0197932 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.0197474 |
| IL6 | interleukin 6 | 0.0192263 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0189796 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0186828 |
| TRIM55 | tripartite motif containing 55 | 0.018206 |
| EFCAB13 | EF-hand calcium binding domain 13 | 0.0177744 |
| ANGPTL4 | angiopoietin-like 4 | 0.0177652 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0177028 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0175927 |
| ZC3H12B | zinc finger CCCH-type containing 12B | 0.0175471 |
| KDM5B | lysine (K)-specific demethylase 5B | 0.017075 |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) | 0.0168119 |
| COL6A1 | collagen, type VI, alpha 1 | 0.0167026 |
| KCNIP4 | Kv channel interacting protein 4 | 0.0163617 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.016236 |
| BICC1 | BicC family RNA binding protein 1 | 0.0161161 |
| TENM2 | teneurin transmembrane protein 2 | 0.0157264 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.015515 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0154133 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0151016 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0149646 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0149243 |
| NABP1 | nucleic acid binding protein 1 | 0.0148726 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | 0.0148203 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | 0.0147639 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0147437 |
| ARHGAP24 | Rho GTPase activating protein 24 | 0.0145306 |
| INHBA | inhibin, beta A | 0.0144758 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0140748 |
| TGFB1 | transforming growth factor, beta 1 | 0.0139844 |
| PTH2R | parathyroid hormone 2 receptor | 0.0137581 |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 | 0.0134443 |
| TLE4 | transducin-like enhancer of split 4 | 0.0134164 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0133865 |
| WFDC10B | WAP four-disulfide core domain 10B | 0.0133419 |
| AFF3 | AF4/FMR2 family, member 3 | 0.0133214 |
| JPH2 | junctophilin 2 | 0.013303 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0132202 |
| BNC2 | basonuclin 2 | 0.0132057 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0131024 |
| RGS17 | regulator of G-protein signaling 17 | 0.0130919 |
| IQCJ | IQ motif containing J | 0.013035 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0130119 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | 0.012977 |
| ADAMTS12 | ADAM metallopeptidase with thrombospondin type 1 motif, 12 | 0.0129011 |
| RNF213 | ring finger protein 213 | 0.0128219 |
| NCKAP5 | NCK-associated protein 5 | 0.0127888 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0127825 |
| DNAH11 | dynein, axonemal, heavy chain 11 | 0.0127598 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0127367 |
| AUTS2 | autism susceptibility candidate 2 | 0.0124467 |
| CCBE1 | collagen and calcium binding EGF domains 1 | 0.0123387 |
| RAD51B | RAD51 paralog B | 0.0122897 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | 0.0120649 |
| TRMT11 | tRNA methyltransferase 11 homolog (S. cerevisiae) | 0.0120321 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.01197 |
| FLRT2 | fibronectin leucine rich transmembrane protein 2 | 0.0118857 |
| SH2B3 | SH2B adaptor protein 3 | 0.0118525 |
| CUX1 | cut-like homeobox 1 | 0.0118438 |
| SOX5 | SRY (sex determining region Y)-box 5 | 0.0117995 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0117611 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0115605 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NAMPT | nicotinamide phosphoribosyltransferase | -0.139971 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.133583 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.122647 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.117125 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.101173 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0938336 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0930586 |
| NAV2 | neuron navigator 2 | -0.0886185 |
| MT2A | metallothionein 2A | -0.0878421 |
| RPS6 | ribosomal protein S6 | -0.0813246 |
| MKI67 | marker of proliferation Ki-67 | -0.0756216 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0730372 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0698773 |
| PTMA | prothymosin, alpha | -0.0685073 |
| FN1 | fibronectin 1 | -0.0672806 |
| CENPF | centromere protein F, 350/400kDa | -0.0660432 |
| TMSB10 | thymosin beta 10 | -0.0655494 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0655023 |
| SPAG9 | sperm associated antigen 9 | -0.0615347 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0601188 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0600074 |
| B2M | beta-2-microglobulin | -0.0584195 |
| GOLGA4 | golgin A4 | -0.0581677 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0569057 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0559693 |
| FTL | ferritin, light polypeptide | -0.054479 |
| ARRDC3 | arrestin domain containing 3 | -0.054011 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0516573 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0514931 |
| ANXA2 | annexin A2 | -0.0501099 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0488358 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0473082 |
| LAMP2 | lysosomal-associated membrane protein 2 | -0.0470509 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0464629 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0462157 |
| RPS2 | ribosomal protein S2 | -0.0447616 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0447101 |
| TXNRD1 | thioredoxin reductase 1 | -0.0443967 |
| ANLN | anillin, actin binding protein | -0.044072 |
| TNIP1 | TNFAIP3 interacting protein 1 | -0.0438197 |
| RTN4 | reticulon 4 | -0.0435026 |
| OGA | O-GlcNAcase | -0.0433119 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0432753 |
| ZNF292 | zinc finger protein 292 | -0.0432212 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0423881 |
| MYOF | myoferlin | -0.0419625 |
| RPL23 | ribosomal protein L23 | -0.0409135 |
| PGK1 | phosphoglycerate kinase 1 | -0.0407727 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0405701 |
| HLA-B | major histocompatibility complex, class I, B | -0.0405593 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0404819 |
| PKM | pyruvate kinase, muscle | -0.0398584 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0397465 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0396114 |
| DSTN | destrin (actin depolymerizing factor) | -0.0393284 |
| SAA2 | serum amyloid A2 | -0.0392625 |
| JMJD1C | jumonji domain containing 1C | -0.0387791 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0382442 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0378438 |
| CD44 | CD44 molecule (Indian blood group) | -0.0377556 |
| RPS3 | ribosomal protein S3 | -0.0374665 |
| THBS1 | thrombospondin 1 | -0.0370085 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.037003 |
| CLTC | clathrin, heavy chain (Hc) | -0.0364339 |
| KIF4A | kinesin family member 4A | -0.0361742 |
| RPL12 | ribosomal protein L12 | -0.0357823 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0355987 |
| RPL7 | ribosomal protein L7 | -0.0354601 |
| SFTPA2 | surfactant protein A2 | -0.0354037 |
| CKAP5 | cytoskeleton associated protein 5 | -0.0353239 |
| RPS12 | ribosomal protein S12 | -0.0351633 |
| VIM | vimentin | -0.0351379 |
| CADM1 | cell adhesion molecule 1 | -0.0350886 |
| KLF6 | Kruppel-like factor 6 | -0.0348162 |
| PRRC2C | proline-rich coiled-coil 2C | -0.034789 |
| MATR3 | matrin 3 | -0.0347243 |
| RPLP2 | ribosomal protein, large, P2 | -0.0347025 |
| MSN | moesin | -0.0346491 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0346249 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0343138 |
| PCBP2 | poly(rC) binding protein 2 | -0.0330347 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0328767 |
| RPS19 | ribosomal protein S19 | -0.0327586 |
| RPL19 | ribosomal protein L19 | -0.0327262 |
| RPL36A | ribosomal protein L36a | -0.0327008 |
| SBF2 | SET binding factor 2 | -0.0326696 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0325295 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0322948 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0321588 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | -0.0321195 |
| ACTG1 | actin gamma 1 | -0.0317386 |
| TPM4 | tropomyosin 4 | -0.0315875 |
| PHIP | pleckstrin homology domain interacting protein | -0.0315765 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0314935 |
| MX1 | MX dynamin-like GTPase 1 | -0.0313005 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0312098 |
| CCNL1 | cyclin L1 | -0.0311432 |
| XPO1 | exportin 1 | -0.0307095 |
| SYAP1 | synapse associated protein 1 | -0.0304436 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0302245 |