| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tucidinostat perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Tucidinostat_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FNDC3B | fibronectin type III domain containing 3B | 0.088678 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0756412 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0709264 |
| SVIL | supervillin | 0.0640014 |
| AHNAK | AHNAK nucleoprotein | 0.0518303 |
| ANGPTL4 | angiopoietin-like 4 | 0.0517315 |
| FMNL2 | formin-like 2 | 0.0516308 |
| HMGA2 | high mobility group AT-hook 2 | 0.0487438 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0485276 |
| SDC4 | syndecan 4 | 0.0456613 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0450654 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0436191 |
| EGFR | epidermal growth factor receptor | 0.0425711 |
| IER3 | immediate early response 3 | 0.0395844 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0377405 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0366783 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0366646 |
| FLNB | filamin B, beta | 0.0356065 |
| PRR16 | proline rich 16 | 0.0349088 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0329206 |
| SKIL | SKI-like proto-oncogene | 0.0328714 |
| INTS6 | integrator complex subunit 6 | 0.0327817 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.032536 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | 0.0323498 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.032143 |
| RIGI | RNA sensor RIG-I | 0.0314904 |
| RAI14 | retinoic acid induced 14 | 0.0312651 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0302568 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.03025 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0295189 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0291984 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0290802 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.028976 |
| PRSS23 | protease, serine, 23 | 0.0283518 |
| RNF213 | ring finger protein 213 | 0.0280706 |
| NDRG1 | N-myc downstream regulated 1 | 0.0279124 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0278471 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0277686 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0276864 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0274066 |
| TMSB10 | thymosin beta 10 | 0.0272879 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.0269869 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.0267686 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0267148 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0264803 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0262351 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0260333 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | 0.0258527 |
| EGR1 | early growth response 1 | 0.0258492 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0250696 |
| ITGAV | integrin, alpha V | 0.024949 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.0249462 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.024874 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0247455 |
| CYTH1 | cytohesin 1 | 0.0247112 |
| BPTF | bromodomain PHD finger transcription factor | 0.0245269 |
| TCF12 | transcription factor 12 | 0.0245252 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0239615 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.0234883 |
| ANXA2 | annexin A2 | 0.0228725 |
| INSIG1 | insulin induced gene 1 | 0.0227477 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.022691 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.022619 |
| IL1RAP | interleukin 1 receptor accessory protein | 0.0225987 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.022585 |
| HLA-A | major histocompatibility complex, class I, A | 0.022505 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0224562 |
| CCL5 | chemokine (C-C motif) ligand 5 | 0.022111 |
| JMJD1C | jumonji domain containing 1C | 0.0219219 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0217579 |
| MYO1E | myosin IE | 0.0217397 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0215894 |
| PCED1B | PC-esterase domain containing 1B | 0.0214949 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.021216 |
| LAMA5 | laminin, alpha 5 | 0.0211682 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.0211279 |
| WWOX | WW domain containing oxidoreductase | 0.0210951 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | 0.0208917 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0205667 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0205547 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | 0.0202755 |
| KLHL29 | kelch-like family member 29 | 0.0201228 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0196455 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | 0.0195901 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0195589 |
| PDGFA | platelet-derived growth factor alpha polypeptide | 0.0192843 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.018992 |
| PDE8A | phosphodiesterase 8A | 0.0188092 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0183397 |
| AHR | aryl hydrocarbon receptor | 0.0182625 |
| CTSC | cathepsin C | 0.0182513 |
| RAB27A | RAB27A, member RAS oncogene family | 0.0180333 |
| DOCK3 | dedicator of cytokinesis 3 | 0.0180252 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0180183 |
| UBC | ubiquitin C | 0.0178775 |
| SATB2 | SATB homeobox 2 | 0.0178488 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.0178166 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0177073 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0176272 |
| EZR | ezrin | 0.0174946 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.131183 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.107933 |
| GOLGA4 | golgin A4 | -0.106268 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.104768 |
| RBM39 | RNA binding motif protein 39 | -0.0949501 |
| TPX2 | TPX2, microtubule-associated | -0.0921502 |
| CENPF | centromere protein F, 350/400kDa | -0.0916773 |
| SMYD3 | SET and MYND domain containing 3 | -0.08569 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0856771 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0687867 |
| NUP58 | nucleoporin 58 | -0.0680191 |
| PTMA | prothymosin, alpha | -0.0678244 |
| YBX3 | Y box binding protein 3 | -0.0672104 |
| ANLN | anillin, actin binding protein | -0.0663922 |
| SPAG9 | sperm associated antigen 9 | -0.0644378 |
| CKAP5 | cytoskeleton associated protein 5 | -0.0632228 |
| CHD1 | chromodomain helicase DNA binding protein 1 | -0.061808 |
| KIF5B | kinesin family member 5B | -0.0604245 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0599228 |
| CKAP2 | cytoskeleton associated protein 2 | -0.0592415 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0592237 |
| ATM | ATM serine/threonine kinase | -0.0587658 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0581759 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0572941 |
| ANKRD28 | ankyrin repeat domain 28 | -0.054472 |
| CPNE1 | copine I | -0.0540517 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0539049 |
| LDHA | lactate dehydrogenase A | -0.0532197 |
| MRE11 | MRE11 homolog, double strand break repair nuclease | -0.0528753 |
| SMC4 | structural maintenance of chromosomes 4 | -0.051505 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0511364 |
| TXNRD1 | thioredoxin reductase 1 | -0.0487375 |
| RDX | radixin | -0.0475974 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | -0.0475363 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.047489 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0463386 |
| MATR3 | matrin 3 | -0.0449088 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0447889 |
| SNX14 | sorting nexin 14 | -0.0445892 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0442183 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0434121 |
| CLTC | clathrin, heavy chain (Hc) | -0.0424714 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0423203 |
| TM9SF2 | transmembrane 9 superfamily member 2 | -0.0414494 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0407191 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0407078 |
| SETD5 | SET domain containing 5 | -0.0401879 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.0397081 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0396459 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0389857 |
| NKTR | natural killer cell triggering receptor | -0.0387302 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0386502 |
| TPR | translocated promoter region, nuclear basket protein | -0.0386492 |
| YAP1 | Yes-associated protein 1 | -0.0382913 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0377776 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0372419 |
| DEK | DEK proto-oncogene | -0.0371009 |
| DIAPH3 | diaphanous-related formin 3 | -0.0370873 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | -0.0369218 |
| KIF4A | kinesin family member 4A | -0.0363007 |
| RRBP1 | ribosome binding protein 1 | -0.035845 |
| GOLT1B | golgi transport 1B | -0.0353122 |
| PHF20 | PHD finger protein 20 | -0.0350376 |
| HMGB2 | high mobility group box 2 | -0.0346804 |
| HSPA8 | heat shock 70kDa protein 8 | -0.034335 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) | -0.0342262 |
| CEP57 | centrosomal protein 57kDa | -0.0340258 |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase | -0.033928 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0329265 |
| LMO7 | LIM domain 7 | -0.0327117 |
| NAV2 | neuron navigator 2 | -0.0326454 |
| NCKAP1 | NCK-associated protein 1 | -0.0324302 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0320279 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | -0.031931 |
| TFRC | transferrin receptor | -0.0318671 |
| APOLD1 | apolipoprotein L domain containing 1 | -0.0318135 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0316076 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0315508 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0314791 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.03136 |
| METTL15 | methyltransferase like 15 | -0.0313303 |
| ZC3H13 | zinc finger CCCH-type containing 13 | -0.0312657 |
| MKI67 | marker of proliferation Ki-67 | -0.0312451 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | -0.0311774 |
| AKAP10 | A kinase (PRKA) anchor protein 10 | -0.0311162 |
| GAS2L3 | growth arrest-specific 2 like 3 | -0.0310677 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0305823 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0303486 |
| KIF23 | kinesin family member 23 | -0.0301344 |
| RPL15 | ribosomal protein L15 | -0.0300848 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.02999 |
| WDPCP | WD repeat containing planar cell polarity effector | -0.0299582 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0298506 |
| HMMR | hyaluronan-mediated motility receptor (RHAMM) | -0.02969 |
| OSBPL6 | oxysterol binding protein-like 6 | -0.0294813 |
| PHIP | pleckstrin homology domain interacting protein | -0.0292458 |
| TMEM167A | transmembrane protein 167A | -0.0291093 |
| AHCTF1 | AT hook containing transcription factor 1 | -0.028642 |
| CLINT1 | clathrin interactor 1 | -0.0286104 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0284181 |
