Typhoid Fever Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A primary bacterial infectious disease that is a communicable systemic illness, has_material_basis_in Salmonella enterica subsp enterica serovar Typhi, which is transmitted_by ingestion of food or water contaminated with the feces of an infected person. The infection has_symptom fever, has_symptom diarrhea, has_symptom prostration, has_symptom headache, has_symptom splenomegaly, has_symptom liver enlargement, has_symptom eruption of rose-colored spots, and has_symptom leukopenia. (Human Disease Ontology, DOID_13258)
External Link https://www.disgenet.org/browser/0/1/0/C0041466
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Genes

30 genes associated with the disease Typhoid Fever in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)
ACTB actin, beta
CCR6 chemokine (C-C motif) receptor 6
CCR9 chemokine (C-C motif) receptor 9
CD38 CD38 molecule
CDK2AP1 cyclin-dependent kinase 2 associated protein 1
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CRP C-reactive protein, pentraxin-related
FLNA filamin A, alpha
GYPA glycophorin A (MNS blood group)
GYPB glycophorin B (MNS blood group)
GYPE glycophorin E (MNS blood group)
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL24 interleukin 24
LRP5 low density lipoprotein receptor-related protein 5
LTB lymphotoxin beta (TNF superfamily, member 3)
MYD88 myeloid differentiation primary response 88
PACRG PARK2 co-regulated
PARK2 parkin RBR E3 ubiquitin protein ligase
RBM45 RNA binding motif protein 45
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
TLR4 toll-like receptor 4
TLR5 toll-like receptor 5
TLR9 toll-like receptor 9
TNF tumor necrosis factor
VAC14 Vac14 homolog (S. cerevisiae)
VDAC1 voltage-dependent anion channel 1