U-118-MG Gene Set

Dataset COSMIC Cell Line Gene Mutation Profiles
Category genomics
Type cell line
Description Human neuronal glioblastoma (grade III) cell line. (BRENDA Tissue and Enzyme Source Ontology, BTO_0004605)
Similar Terms
Downloads & Tools

Genes

294 genes mutated in the U-118-MG cell line from the COSMIC Cell Line Gene Mutation Profiles dataset.

Symbol Name
ABCB5 ATP-binding cassette, sub-family B (MDR/TAP), member 5
ACACB acetyl-CoA carboxylase beta
ACOX1 acyl-CoA oxidase 1, palmitoyl
ACSM5 acyl-CoA synthetase medium-chain family member 5
ADAM17 ADAM metallopeptidase domain 17
ADAMTSL2 ADAMTS-like 2
ADCY4 adenylate cyclase 4
ADRBK1 adrenergic, beta, receptor kinase 1
ADRBK2 adrenergic, beta, receptor kinase 2
AGR3 anterior gradient 3
AIM1L absent in melanoma 1-like
AKAP9 A kinase (PRKA) anchor protein 9
ALDH1L1 aldehyde dehydrogenase 1 family, member L1
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase
ANAPC4 anaphase promoting complex subunit 4
ANKRD12 ankyrin repeat domain 12
ANKRD42 ankyrin repeat domain 42
ANKS4B ankyrin repeat and sterile alpha motif domain containing 4B
APCS amyloid P component, serum
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11
ARHGEF25 Rho guanine nucleotide exchange factor (GEF) 25
ARHGEF4 Rho guanine nucleotide exchange factor (GEF) 4
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
ARHGEF9 Cdc42 guanine nucleotide exchange factor (GEF) 9
ARMC5 armadillo repeat containing 5
ARPP21 cAMP-regulated phosphoprotein, 21kDa
ATP7B ATPase, Cu++ transporting, beta polypeptide
AVPR1A arginine vasopressin receptor 1A
B3GALT2 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
BARD1 BRCA1 associated RING domain 1
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein)
BMP1 bone morphogenetic protein 1
BMP6 bone morphogenetic protein 6
BPTF bromodomain PHD finger transcription factor
BRINP2 bone morphogenetic protein/retinoic acid inducible neural-specific 2
BSN bassoon presynaptic cytomatrix protein
BST1 bone marrow stromal cell antigen 1
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
BZW2 basic leucine zipper and W2 domains 2
C1R complement component 1, r subcomponent
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CAMK1 calcium/calmodulin-dependent protein kinase I
CAPN14 calpain 14
CARS cysteinyl-tRNA synthetase
CBS cystathionine-beta-synthase
CCDC38 coiled-coil domain containing 38
CCK cholecystokinin
CCND2 cyclin D2
CCS copper chaperone for superoxide dismutase
CD5 CD5 molecule
CDC123 cell division cycle 123
CDH8 cadherin 8, type 2
CEP162 centrosomal protein 162kDa
CEP192 centrosomal protein 192kDa
CEP295 centrosomal protein 295kDa
CFAP70 cilia and flagella associated protein 70
CHD7 chromodomain helicase DNA binding protein 7
CHMP4C charged multivesicular body protein 4C
CHSY3 chondroitin sulfate synthase 3
CIB3 calcium and integrin binding family member 3
COBL cordon-bleu WH2 repeat protein
COL14A1 collagen, type XIV, alpha 1
COL4A6 collagen, type IV, alpha 6
COL5A1 collagen, type V, alpha 1
CPXM2 carboxypeptidase X (M14 family), member 2
CSMD1 CUB and Sushi multiple domains 1
CSMD2 CUB and Sushi multiple domains 2
CSMD3 CUB and Sushi multiple domains 3
CYP11B1 cytochrome P450, family 11, subfamily B, polypeptide 1
DEPDC7 DEP domain containing 7
DIP2C DIP2 disco-interacting protein 2 homolog C (Drosophila)
DNAH1 dynein, axonemal, heavy chain 1
DNAH6 dynein, axonemal, heavy chain 6
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DPH3P1 diphthamide biosynthesis 3 pseudogene 1
DPY19L1 dpy-19-like 1 (C. elegans)
DRD2 dopamine receptor D2
DSG2 desmoglein 2
DSP desmoplakin
DYNC1I1 dynein, cytoplasmic 1, intermediate chain 1
ECT2L epithelial cell transforming 2 like
ELAC2 elaC ribonuclease Z 2
ELOVL2 ELOVL fatty acid elongase 2
ELOVL7 ELOVL fatty acid elongase 7
EPHA7 EPH receptor A7
ERCC3 excision repair cross-complementation group 3
EXOC2 exocyst complex component 2
FABP3 fatty acid binding protein 3, muscle and heart
FAM120B family with sequence similarity 120B
FAM135B family with sequence similarity 135, member B
FAM13C family with sequence similarity 13, member C
FAM84B family with sequence similarity 84, member B
FAT2 FAT atypical cadherin 2
FAT3 FAT atypical cadherin 3
FBN3 fibrillin 3
FCGBP Fc fragment of IgG binding protein
FMN2 formin 2
FNTB farnesyltransferase, CAAX box, beta
FOXN3 forkhead box N3
FRG1 FSHD region gene 1
GABRR1 gamma-aminobutyric acid (GABA) A receptor, rho 1
GAS2L3 growth arrest-specific 2 like 3
GCLC glutamate-cysteine ligase, catalytic subunit
GEMIN4 gem (nuclear organelle) associated protein 4
GIMAP2 GTPase, IMAP family member 2
GLYAT glycine-N-acyltransferase
GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
GPC5 glypican 5
GPR108 G protein-coupled receptor 108
GPR55 G protein-coupled receptor 55
GRAMD1A GRAM domain containing 1A
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A
GRM7 glutamate receptor, metabotropic 7
GUCA2B guanylate cyclase activator 2B (uroguanylin)
HIST1H2AL histone cluster 1, H2al
HIST3H3 histone cluster 3, H3
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HMGXB4 HMG box domain containing 4
HOXA1 homeobox A1
HRNR hornerin
IGSF10 immunoglobulin superfamily, member 10
IGSF5 immunoglobulin superfamily, member 5
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IL18BP interleukin 18 binding protein
IL7R interleukin 7 receptor
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae)
INPP5J inositol polyphosphate-5-phosphatase J
IZUMO1R IZUMO1 receptor, JUNO
JAG2 jagged 2
JAK2 Janus kinase 2
KCNT1 potassium channel, sodium activated subfamily T, member 1
KIAA0556 KIAA0556
KIAA1671 KIAA1671
KIF21B kinesin family member 21B
KIF3A kinesin family member 3A
KLHL1 kelch-like family member 1
LCA5L Leber congenital amaurosis 5-like
LCTL lactase-like
LENG8 leukocyte receptor cluster (LRC) member 8
LEO1 Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
LGI3 leucine-rich repeat LGI family, member 3
LILRA4 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 4
LIN7C lin-7 homolog C (C. elegans)
LMBR1 limb development membrane protein 1
LMTK2 lemur tyrosine kinase 2
LPCAT4 lysophosphatidylcholine acyltransferase 4
LRP2 low density lipoprotein receptor-related protein 2
LRRC37A3 leucine rich repeat containing 37, member A3
LRRC6 leucine rich repeat containing 6
LUC7L LUC7-like (S. cerevisiae)
MADD MAP-kinase activating death domain
MAP2K6 mitogen-activated protein kinase kinase 6
MBD5 methyl-CpG binding domain protein 5
MFSD2B major facilitator superfamily domain containing 2B
MIDN midnolin
MNMIP1 manchette microtubule inner protein 1
MPDZ multiple PDZ domain protein
MTA3 metastasis associated 1 family, member 3
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MUC12 mucin 12, cell surface associated
MUC19 mucin 19, oligomeric
MUC4 mucin 4, cell surface associated
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
MUC5B mucin 5B, oligomeric mucus/gel-forming
MX2 MX dynamin-like GTPase 2
MYH3 myosin, heavy chain 3, skeletal muscle, embryonic
N6AMT1 N-6 adenine-specific DNA methyltransferase 1 (putative)
NCKAP5L NCK-associated protein 5-like
NEO1 neogenin 1
NEURL1 neuralized E3 ubiquitin protein ligase 1
NLRP4 NLR family, pyrin domain containing 4
NMBR neuromedin B receptor
NPFFR2 neuropeptide FF receptor 2
NSUN5 NOP2/Sun domain family, member 5
NVL nuclear VCP-like
OGFOD2 2-oxoglutarate and iron-dependent oxygenase domain containing 2
OR2L13 olfactory receptor, family 2, subfamily L, member 13
OR2T33 olfactory receptor, family 2, subfamily T, member 33
OR4C5 olfactory receptor, family 4, subfamily C, member 5 (gene/pseudogene)
OR51E2 olfactory receptor, family 51, subfamily E, member 2
OR6M1 olfactory receptor, family 6, subfamily M, member 1
OSBP2 oxysterol binding protein 2
OTOG otogelin
PARD6B par-6 family cell polarity regulator beta
PARK2 parkin RBR E3 ubiquitin protein ligase
PARP12 poly (ADP-ribose) polymerase family, member 12
PC pyruvate carboxylase
PCDHB13 protocadherin beta 13
PCDHGA11 protocadherin gamma subfamily A, 11
PCNXL4 pecanex-like 4 (Drosophila)
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PDZD2 PDZ domain containing 2
PGD phosphogluconate dehydrogenase
PHF3 PHD finger protein 3
PKD1 polycystic kidney disease 1 (autosomal dominant)
PLEKHB2 pleckstrin homology domain containing, family B (evectins) member 2
PLXNB2 plexin B2
PNPLA6 patatin-like phospholipase domain containing 6
POGZ pogo transposable element with ZNF domain
POLR1A polymerase (RNA) I polypeptide A, 194kDa
PPP1R10 protein phosphatase 1, regulatory subunit 10
PPP2R2B protein phosphatase 2, regulatory subunit B, beta
PRDM5 PR domain containing 5
PRMT9 protein arginine methyltransferase 9
PRR14 proline rich 14
PRRT3 proline-rich transmembrane protein 3
PRX periaxin
PTCHD2 patched domain containing 2
PTEN phosphatase and tensin homolog
PTPRJ protein tyrosine phosphatase, receptor type, J
PTPRS protein tyrosine phosphatase, receptor type, S
RASGEF1B RasGEF domain family, member 1B
RBM19 RNA binding motif protein 19
RBM28 RNA binding motif protein 28
RECQL5 RecQ protein-like 5
RGAG4 retrotransposon gag domain containing 4
RNF157 ring finger protein 157
RNPEP arginyl aminopeptidase (aminopeptidase B)
RORB RAR-related orphan receptor B
RPAP3 RNA polymerase II associated protein 3
RUNX2 runt-related transcription factor 2
SACM1L SAC1 suppressor of actin mutations 1-like (yeast)
SAMD9L sterile alpha motif domain containing 9-like
SEC16A SEC16 homolog A (S. cerevisiae)
SENP2 SUMO1/sentrin/SMT3 specific peptidase 2
SH3BP2 SH3-domain binding protein 2
SH3GL3 SH3-domain GRB2-like 3
SHROOM4 shroom family member 4
SLC26A8 solute carrier family 26 (anion exchanger), member 8
SLC27A5 solute carrier family 27 (fatty acid transporter), member 5
SLC39A9 solute carrier family 39, member 9
SLC4A11 solute carrier family 4, sodium borate transporter, member 11
SLC9A9 solute carrier family 9, subfamily A (NHE9, cation proton antiporter 9), member 9
SLIT1 slit homolog 1 (Drosophila)
SNUPN snurportin 1
SOGA1 suppressor of glucose, autophagy associated 1
SPAG1 sperm associated antigen 1
SRRM4 serine/arginine repetitive matrix 4
SSX5 synovial sarcoma, X breakpoint 5
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
ST6GAL2 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2
STAG1 stromal antigen 1
STRBP spermatid perinuclear RNA binding protein
SULF2 sulfatase 2
SYNPO2 synaptopodin 2
TAF1A TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa
TARS threonyl-tRNA synthetase
TAS2R8 taste receptor, type 2, member 8
TAS2R9 taste receptor, type 2, member 9
TBC1D30 TBC1 domain family, member 30
TBL1X transducin (beta)-like 1X-linked
TDRD5 tudor domain containing 5
TESK2 testis-specific kinase 2
TEX13B testis expressed 13B
TGM4 transglutaminase 4
THAP5 THAP domain containing 5
TMC4 transmembrane channel-like 4
TMEM108 transmembrane protein 108
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TP53 tumor protein p53
TRIM51 tripartite motif-containing 51
TRIM65 tripartite motif containing 65
TRIM9 tripartite motif containing 9
TRIML1 tripartite motif family-like 1
TRMT12 tRNA methyltransferase 12 homolog (S. cerevisiae)
TRRAP transformation/transcription domain-associated protein
TSPYL4 TSPY-like 4
TTC17 tetratricopeptide repeat domain 17
TUBB4B tubulin, beta 4B class IVb
UCKL1 uridine-cytidine kinase 1-like 1
UNC79 unc-79 homolog (C. elegans)
UTP20 UTP20, small subunit (SSU) processome component, homolog (yeast)
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
VPS13A vacuolar protein sorting 13 homolog A (S. cerevisiae)
VPS35 vacuolar protein sorting 35 homolog (S. cerevisiae)
WWOX WW domain containing oxidoreductase
XDH xanthine dehydrogenase
XIRP2 xin actin binding repeat containing 2
YBX1 Y box binding protein 1
ZBTB10 zinc finger and BTB domain containing 10
ZC3H10 zinc finger CCCH-type containing 10
ZFHX4 zinc finger homeobox 4
ZNF114 zinc finger protein 114
ZNF224 zinc finger protein 224
ZNF253 zinc finger protein 253
ZNF317 zinc finger protein 317
ZNF441 zinc finger protein 441
ZNF496 zinc finger protein 496
ZNF561 zinc finger protein 561
ZNF725P zinc finger protein 725, pseudogene
ZNF837 zinc finger protein 837
ZNF850 zinc finger protein 850
ZSCAN31 zinc finger and SCAN domain containing 31