UBA2 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description ubiquitin-like modifier activating enzyme 2|Posttranslational modification of proteins by the addition of the small protein SUMO (see SUMO1; MIM 601912), or sumoylation, regulates protein structure and intracellular localization. SAE1 (MIM 613294) and UBA2 form a heterodimer that functions as a SUMO-activating enzyme for the sumoylation of proteins (Okuma et al., 1999 [PubMed 9920803]).[supplied by OMIM, Mar 2010] (NCBI Entrez Gene Database, 10054)
External Link http://www.ncbi.nlm.nih.gov/gene/10054
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Genes

97 interacting proteins for UBA2 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
AHCYL1 adenosylhomocysteinase-like 1
ARIH1 ariadne RBR E3 ubiquitin protein ligase 1
ATP6V1B2 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2
BAG3 BCL2-associated athanogene 3
BEND3 BEN domain containing 3
BRIX1 BRX1, biogenesis of ribosomes
CALU calumenin
CBS cystathionine-beta-synthase
CHAMP1 chromosome alignment maintaining phosphoprotein 1
CHMP5 charged multivesicular body protein 5
CLNS1A chloride channel, nucleotide-sensitive, 1A
CTPS1 CTP synthase 1
CTSC cathepsin C
CWC22 CWC22 spliceosome-associated protein
DHX15 DEAH (Asp-Glu-Ala-His) box helicase 15
E2F1 E2F transcription factor 1
EGFR epidermal growth factor receptor
EHD4 EH-domain containing 4
ETV4 ets variant 4
GATAD2B GATA zinc finger domain containing 2B
HLA-B major histocompatibility complex, class I, B
HNRNPUL2 heterogeneous nuclear ribonucleoprotein U-like 2
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
INTS12 integrator complex subunit 12
IREB2 iron-responsive element binding protein 2
IRF2BPL interferon regulatory factor 2 binding protein-like
KIAA0368 KIAA0368
KIAA1598
KIFC1 kinesin family member C1
LBR lamin B receptor
MCC mutated in colorectal cancers
MCM4 minichromosome maintenance complex component 4
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase
MYL1 myosin, light chain 1, alkali; skeletal, fast
NAP1L1 nucleosome assembly protein 1-like 1
NEDD8 neural precursor cell expressed, developmentally down-regulated 8
NPLOC4 nuclear protein localization 4 homolog (S. cerevisiae)
NRF1 nuclear respiratory factor 1
P4HB prolyl 4-hydroxylase, beta polypeptide
PARK7 parkinson protein 7
PAX3 paired box 3
PCBD1 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha
PDE12 phosphodiesterase 12
PDLIM5 PDZ and LIM domain 5
PKM pyruvate kinase, muscle
PLAA phospholipase A2-activating protein
PLIN3 perilipin 3
PLOD1 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1
POLR3D polymerase (RNA) III (DNA directed) polypeptide D, 44kDa
PRPF6 pre-mRNA processing factor 6
PWP2 PWP2 periodic tryptophan protein homolog (yeast)
RABGGTA Rab geranylgeranyltransferase, alpha subunit
RAD23B RAD23 homolog B (S. cerevisiae)
RANBP2 RAN binding protein 2
RANGAP1 Ran GTPase activating protein 1
RNF168 ring finger protein 168, E3 ubiquitin protein ligase
RNF169 ring finger protein 169
RNF4 ring finger protein 4
RPS15A ribosomal protein S15a
SAE1 SUMO1 activating enzyme subunit 1
SEPHS2 selenophosphate synthetase 2
SERBP1 SERPINE1 mRNA binding protein 1
SIN3A SIN3 transcription regulator family member A
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2
SNCG synuclein, gamma (breast cancer-specific protein 1)
SP100 SP100 nuclear antigen
SRP14 signal recognition particle 14kDa (homologous Alu RNA binding protein)
SRSF2 serine/arginine-rich splicing factor 2
SRXN1 sulfiredoxin 1
SSB Sjogren syndrome antigen B (autoantigen La)
SSRP1 structure specific recognition protein 1
STMN2 stathmin 2
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
SUMO1 small ubiquitin-like modifier 1
SUMO2 small ubiquitin-like modifier 2
SUMO3 small ubiquitin-like modifier 3
TACC3 transforming, acidic coiled-coil containing protein 3
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
TCEAL4 transcription elongation factor A (SII)-like 4
THADA thyroid adenoma associated
TLE3 transducin-like enhancer of split 3
TOM1L2 target of myb1-like 2 (chicken)
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRIP6 thyroid hormone receptor interactor 6
TSR1 TSR1, 20S rRNA accumulation, homolog (S. cerevisiae)
TTC9C tetratricopeptide repeat domain 9C
UBC ubiquitin C
UBE2B ubiquitin-conjugating enzyme E2B
UBE2I ubiquitin-conjugating enzyme E2I
UBQLN2 ubiquilin 2
UNK unkempt family zinc finger
USP34 ubiquitin specific peptidase 34
YAP1 Yes-associated protein 1
ZBTB33 zinc finger and BTB domain containing 33
ZC3H11A zinc finger CCCH-type containing 11A
ZFYVE19 zinc finger, FYVE domain containing 19
ZNHIT6 zinc finger, HIT-type containing 6