UBE2A Gene Set

Dataset MSigDB Cancer Gene Co-expression Modules
Category transcriptomics
Type co-expressed gene
Description ubiquitin-conjugating enzyme E2A|The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, ubiquitin-conjugating enzymes, and ubiquitin-protein ligases. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is required for post-replicative DNA damage repair, and may play a role in transcriptional regulation. Mutations in this gene are associated with mental retardation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013] (NCBI Entrez Gene Database, 7319)
External Link http://www.broadinstitute.org/gsea/msigdb/cards/MORF_UBE2A
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Genes

49 co-expressed genes for UBE2A from the MSigDB Cancer Gene Co-expression Modules dataset.

Symbol Name
ARCN1 archain 1
ARF5 ADP-ribosylation factor 5
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa
ATP6V1F ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F
ATXN2 ataxin 2
CALM2 calmodulin 2 (phosphorylase kinase, delta)
CANX calnexin
CAPZB capping protein (actin filament) muscle Z-line, beta
CUL4B cullin 4B
DDB1 damage-specific DNA binding protein 1, 127kDa
DNAJC13 DnaJ (Hsp40) homolog, subfamily C, member 13
DNPEP aspartyl aminopeptidase
FAM134C family with sequence similarity 134, member C
FBXW11 F-box and WD repeat domain containing 11
HTATSF1 HIV-1 Tat specific factor 1
ILVBL ilvB (bacterial acetolactate synthase)-like
LASP1 LIM and SH3 protein 1
MEA1 male-enhanced antigen 1
METAP1 methionyl aminopeptidase 1
MRPL28 mitochondrial ribosomal protein L28
MYL12B myosin, light chain 12B, regulatory
NUBP1 nucleotide binding protein 1
PARN poly(A)-specific ribonuclease
PDCD10 programmed cell death 10
PEX11B peroxisomal biogenesis factor 11 beta
PPP1R11 protein phosphatase 1, regulatory (inhibitor) subunit 11
PPP1R7 protein phosphatase 1, regulatory subunit 7
PRKAG1 protein kinase, AMP-activated, gamma 1 non-catalytic subunit
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha
PRPSAP1 phosphoribosyl pyrophosphate synthetase-associated protein 1
PSMB6 proteasome (prosome, macropain) subunit, beta type, 6
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
RAB11A RAB11A, member RAS oncogene family
RAB1A RAB1A, member RAS oncogene family
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RASA1 RAS p21 protein activator (GTPase activating protein) 1
RPRD2 regulation of nuclear pre-mRNA domain containing 2
SARS seryl-tRNA synthetase
SEC22B SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene)
SMAD2 SMAD family member 2
TBCB tubulin folding cofactor B
TPR translocated promoter region, nuclear basket protein
UBA1 ubiquitin-like modifier activating enzyme 1
UBE2A ubiquitin-conjugating enzyme E2A
UFD1L ubiquitin fusion degradation 1 like (yeast)
VGLL4 vestigial-like family member 4
XPC xeroderma pigmentosum, complementation group C
ZNHIT1 zinc finger, HIT-type containing 1
ZZZ3 zinc finger, ZZ-type containing 3