UBE2V2 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description ubiquitin-conjugating enzyme E2 variant 2|Ubiquitin-conjugating enzyme E2 variant proteins constitute a distinct subfamily within the E2 protein family. They have sequence similarity to other ubiquitin-conjugating enzymes but lack the conserved cysteine residue that is critical for the catalytic activity of E2s. The protein encoded by this gene also shares homology with ubiquitin-conjugating enzyme E2 variant 1 and yeast MMS2 gene product. It may be involved in the differentiation of monocytes and enterocytes. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 7336)
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Genes

329 genes differentially expressed following the UBE2V2 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
IMPG2 interphotoreceptor matrix proteoglycan 2 3.3726
C1ORF105 chromosome 1 open reading frame 105 3.3726
THPO thrombopoietin 3.3726
TMEM71 transmembrane protein 71 3.3726
ASPDH aspartate dehydrogenase domain containing 3.3726
TRPV5 transient receptor potential cation channel, subfamily V, member 5 3.3726
TMEM86B transmembrane protein 86B 3.3726
MSX1 msh homeobox 1 3.3726
TF transferrin 3.3726
LRG1 leucine-rich alpha-2-glycoprotein 1 3.3726
DLX4 distal-less homeobox 4 3.3726
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 3.3726
EFCAB9 EF-hand calcium binding domain 9 3.3726
SMIM31 small integral membrane protein 31 3.3726
ANXA13 annexin A13 3.3726
THTPA thiamine triphosphatase 3.3726
DNAI2 dynein, axonemal, intermediate chain 2 3.3726
SLC25A45 solute carrier family 25, member 45 3.34589
CDX2 caudal type homeobox 2 3.34589
OR10A2 olfactory receptor, family 10, subfamily A, member 2 3.34589
FOXI1 forkhead box I1 3.34589
ADAMTS15 ADAM metallopeptidase with thrombospondin type 1 motif, 15 3.34589
TXNDC8 thioredoxin domain containing 8 (spermatozoa) 3.34589
UPK3B uroplakin 3B 3.34589
FPR2 formyl peptide receptor 2 3.34589
SLC26A9 solute carrier family 26 (anion exchanger), member 9 3.34589
TSSK4 testis-specific serine kinase 4 3.34589
ENAM enamelin 3.34589
LAX1 lymphocyte transmembrane adaptor 1 3.34589
CHRND cholinergic receptor, nicotinic, delta (muscle) 3.34589
FAM90A1 family with sequence similarity 90, member A1 3.34589
SHE Src homology 2 domain containing E 3.34589
SSTR1 somatostatin receptor 1 3.34589
HBZ hemoglobin, zeta 3.34589
ATOH1 atonal homolog 1 (Drosophila) 3.34589
ADH7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide 3.34589
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 3.34589
NWD1 NACHT and WD repeat domain containing 1 3.34589
SPAG8 sperm associated antigen 8 3.34589
FAM9B family with sequence similarity 9, member B 3.34589
CLEC5A C-type lectin domain family 5, member A 3.34589
CPB1 carboxypeptidase B1 (tissue) 3.34589
SIGLEC9 sialic acid binding Ig-like lectin 9 3.34589
RSPO1 R-spondin 1 3.34589
C12ORF71 chromosome 12 open reading frame 71 3.34589
FHL5 four and a half LIM domains 5 3.34589
RFPL3 ret finger protein-like 3 3.34589
BIRC3 baculoviral IAP repeat containing 3 3.34589
PTGER3 prostaglandin E receptor 3 (subtype EP3) 3.34589
ZNF556 zinc finger protein 556 3.34589
SPP2 secreted phosphoprotein 2, 24kDa 3.34589
PANO1 proapoptotic nucleolar protein 1 3.34589
ACKR5 atypical chemokine receptor 5 3.34589
DYNLT4 dynein light chain Tctex-type 4 3.34589
TMEM275 transmembrane protein 275 3.34589
RAB6D RAB6D, member RAS oncogene family 3.34589
IRAG2 inositol 1,4,5-triphosphate receptor associated 2 3.34589
EIF2S3B eukaryotic translation initiation factor 2 subunit gamma B 3.34589
TRAPPC3L trafficking protein particle complex 3-like 3.34589
SCEL sciellin 3.34589
ELOVL3 ELOVL fatty acid elongase 3 3.34589
KRT86 keratin 86, type II 3.34589
GARIN6 golgi associated RAB2 interactor family member 6 3.34589
PPDPFL pancreatic progenitor cell differentiation and proliferation factor like 3.34589
CIMAP2 ciliary microtubule associated protein 2 3.34589
GNG14 G protein subunit gamma 14 3.34589
CPNE8-AS1 CPNE8 antisense RNA 1 3.34589
CFAP97D2 CFAP97 domain containing 2 3.34589
SMIM45 small integral membrane protein 45 3.34589
H4C14 H4 clustered histone 14 3.34589
MYMK myomaker, myoblast fusion factor 3.34589
UBE2L5 ubiquitin conjugating enzyme E2 L5 3.34589
SEPTIN12 septin 12 3.34589
SRGN serglycin 3.34589
FMOD fibromodulin 3.34589
TACR2 tachykinin receptor 2 3.34589
ATP2B3 ATPase, Ca++ transporting, plasma membrane 3 3.34589
SLC9A4 solute carrier family 9, subfamily A (NHE4, cation proton antiporter 4), member 4 3.34589
APOBEC1 apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1 3.34589
RNF113B ring finger protein 113B 3.34589
TLR1 toll-like receptor 1 3.34589
NPIPB9 nuclear pore complex interacting protein family, member B9 3.34589
ASIC3 acid sensing (proton gated) ion channel 3 3.34589
LOC124900192 uncharacterized LOC124900192 3.34589
RGS21 regulator of G-protein signaling 21 3.34589
SASH3 SAM and SH3 domain containing 3 3.34589
TBC1D3B TBC1 domain family, member 3B 3.34589
IFIT1B interferon-induced protein with tetratricopeptide repeats 1B 3.34589
FCMR Fc fragment of IgM receptor 3.34589
LY6K lymphocyte antigen 6 complex, locus K 3.34589
ZNF705B zinc finger protein 705B 3.34589
SYT15 synaptotagmin XV 3.34589
MS4A5 membrane-spanning 4-domains, subfamily A, member 5 3.34589
UGT2A1 UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus 3.34589
PCDHGC4 protocadherin gamma subfamily C, 4 3.34589
ANXA10 annexin A10 3.34589
EN1 engrailed homeobox 1 3.34589
LCN1 lipocalin 1 3.34589
KCNC2 potassium channel, voltage gated Shaw related subfamily C, member 2 3.34589
PLA2G4E phospholipase A2, group IVE 3.34589
MAGEB17 melanoma antigen family B17 3.34589
PRSS38 protease, serine, 38 3.34589
PDCD1 programmed cell death 1 3.34589
PRSS55 protease, serine, 55 3.34589
PRH2 proline-rich protein HaeIII subfamily 2 3.34589
TBC1D21 TBC1 domain family, member 21 3.34589
WDFY4 WDFY family member 4 3.34589
DAW1 dynein assembly factor with WDR repeat domains 1 3.34589
SH2D1B SH2 domain containing 1B 3.34589
NXF2B nuclear RNA export factor 2B 3.34589
FADS6 fatty acid desaturase 6 3.34589
POTEJ POTE ankyrin domain family, member J 3.34589
GABRD gamma-aminobutyric acid (GABA) A receptor, delta 3.34589
DLX3 distal-less homeobox 3 3.34589
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) 3.34589
HCRT hypocretin (orexin) neuropeptide precursor 3.34589
IL21R interleukin 21 receptor 3.34589
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9 3.34589
CCL27 chemokine (C-C motif) ligand 27 3.34589
RNASE11 ribonuclease, RNase A family, 11 (non-active) 3.34589
HPX hemopexin 3.34589
C16ORF78 chromosome 16 open reading frame 78 3.34589
C22ORF42 chromosome 22 open reading frame 42 3.34589
PCDHGA3 protocadherin gamma subfamily A, 3 3.34589
LMOD3 leiomodin 3 (fetal) 3.34589
APOF apolipoprotein F 3.34589
WFIKKN2 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 3.34589
OR9Q1 olfactory receptor, family 9, subfamily Q, member 1 3.34589
SERPINB11 serpin peptidase inhibitor, clade B (ovalbumin), member 11 (gene/pseudogene) 3.34589
NYX nyctalopin 3.34589
PADI1 peptidyl arginine deiminase, type I 3.34589
TMPRSS13 transmembrane protease, serine 13 3.34589
TGM6 transglutaminase 6 3.34589
XCR1 chemokine (C motif) receptor 1 3.34589
NPY2R neuropeptide Y receptor Y2 3.34589
DDI1 DNA-damage inducible 1 homolog 1 (S. cerevisiae) 3.34589
SLC38A11 solute carrier family 38, member 11 3.34589
TNMD tenomodulin 3.34589
CEACAM20 carcinoembryonic antigen-related cell adhesion molecule 20 3.34589
CCDC170 coiled-coil domain containing 170 3.34589
CFP complement factor properdin 3.34589
ART1 ADP-ribosyltransferase 1 3.34589
FOXG1 forkhead box G1 3.34589
NLRP8 NLR family, pyrin domain containing 8 3.34589
KRTAP13-4 keratin associated protein 13-4 3.34589
CHST5 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5 3.34589
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5 3.34589
WFDC10A WAP four-disulfide core domain 10A 3.34589
CD8A CD8a molecule 3.34589
OR11G2 olfactory receptor, family 11, subfamily G, member 2 3.34589
TSPAN19 tetraspanin 19 3.34589
TYR tyrosinase 3.34589
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle) 3.34589
RNF222 ring finger protein 222 3.34589
RIPK3 receptor-interacting serine-threonine kinase 3 3.34589
FUT5 fucosyltransferase 5 (alpha (1,3) fucosyltransferase) 3.34589
OR13G1 olfactory receptor, family 13, subfamily G, member 1 3.34589
PHGR1 proline/histidine/glycine-rich 1 3.34589
FAM24B family with sequence similarity 24, member B 3.23743
CTSO cathepsin O 3.23743
IFT70A intraflagellar transport 70A 3.23743
TRPC6 transient receptor potential cation channel, subfamily C, member 6 2.96328
NUDT11 nudix (nucleoside diphosphate linked moiety X)-type motif 11 2.93404
KCNC4 potassium channel, voltage gated Shaw related subfamily C, member 4 2.89312
EMILIN1 elastin microfibril interfacer 1 2.89312
PRMT3 protein arginine methyltransferase 3 2.86374
IKZF2 IKAROS family zinc finger 2 (Helios) 2.73598
FMO3 flavin containing monooxygenase 3 2.69301
HMOX1 heme oxygenase 1 2.63887
ZW10 zw10 kinetochore protein 2.60528
KLHDC9 kelch domain containing 9 2.57223
TSKU tsukushi, small leucine rich proteoglycan 2.57178
GRM1 glutamate receptor, metabotropic 1 2.57178
SEMA4G sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G 2.55002
BDH1 3-hydroxybutyrate dehydrogenase, type 1 2.54591
KLRD1 killer cell lectin-like receptor subfamily D, member 1 2.54032
IPMK inositol polyphosphate multikinase 2.48539
CYB561A3 cytochrome b561 family, member A3 2.46782
RPA3 replication protein A3, 14kDa 2.44604
VPS37D vacuolar protein sorting 37 homolog D (S. cerevisiae) 2.41842
PDGFB platelet-derived growth factor beta polypeptide 2.40513
PEX3 peroxisomal biogenesis factor 3 2.37387
TRIL TLR4 interactor with leucine-rich repeats 2.35434
MPP7 membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7) 2.34917
CA9 carbonic anhydrase IX 2.3477
KRT17 keratin 17, type I 2.3477
PRR15 proline rich 15 2.33706
THEMIS2 thymocyte selection associated family member 2 2.33083
PGA5 pepsinogen 5, group I (pepsinogen A) 2.31868
PCDH12 protocadherin 12 2.29004
AIPL1 aryl hydrocarbon receptor interacting protein-like 1 2.29004
BTN3A1 butyrophilin, subfamily 3, member A1 2.26774
POTEF POTE ankyrin domain family, member F 2.26088
ALX4 ALX homeobox 4 2.26088
LRRC63 leucine rich repeat containing 63 2.26088
TCEAL9 transcription elongation factor A like 9 2.25075
TMEM132E transmembrane protein 132E 2.24973
TMEM129 transmembrane protein 129, E3 ubiquitin protein ligase 2.24479
MOSPD3 motile sperm domain containing 3 2.24479
TOMM40L translocase of outer mitochondrial membrane 40 homolog (yeast)-like 2.24235
TNRC6A trinucleotide repeat containing 6A 2.23532
ANKRD63 ankyrin repeat domain 63 2.21863
CBX8 chromobox homolog 8 2.21863
ACOX2 acyl-CoA oxidase 2, branched chain 2.21863
ADHFE1 alcohol dehydrogenase, iron containing, 1 2.21123
ZNF423 zinc finger protein 423 2.20215
CCDC137 coiled-coil domain containing 137 2.16611
EXOSC1 exosome component 1 2.15881
TRIB3 tribbles pseudokinase 3 2.1511
TRAPPC11 trafficking protein particle complex 11 2.13788
NHSL1 NHS-like 1 2.1247
BAZ2A bromodomain adjacent to zinc finger domain, 2A 2.115
CANT1 calcium activated nucleotidase 1 2.10438
ZBTB45 zinc finger and BTB domain containing 45 2.08971
PTGES3 prostaglandin E synthase 3 (cytosolic) 2.08503
ALG6 ALG6, alpha-1,3-glucosyltransferase 2.07876
MBD6 methyl-CpG binding domain protein 6 2.07876
MLF1 myeloid leukemia factor 1 2.07475
ELF1 E74-like factor 1 (ets domain transcription factor) 2.07175
SOX8 SRY (sex determining region Y)-box 8 2.04536
BRF2 BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit 2.02234
FES FES proto-oncogene, tyrosine kinase 2.01639
VAMP5 vesicle-associated membrane protein 5 2.01303
ZBTB8A zinc finger and BTB domain containing 8A 2.00348
CDCP1 CUB domain containing protein 1 2.00161

decreased expression

Symbol Name Standardized Value
CYP4Z1 cytochrome P450, family 4, subfamily Z, polypeptide 1 -3.3726
RIN1 Ras and Rab interactor 1 -3.3726
RDH5 retinol dehydrogenase 5 (11-cis/9-cis) -3.3726
CXCR5 chemokine (C-X-C motif) receptor 5 -3.3726
MMP28 matrix metallopeptidase 28 -3.3726
VSTM2A V-set and transmembrane domain containing 2A -3.3726
DUSP13B dual specificity phosphatase 13B -3.3726
BAAT bile acid CoA:amino acid N-acyltransferase -3.34589
SPNS2 spinster homolog 2 (Drosophila) -3.34589
MYO1G myosin IG -3.34589
GYS2 glycogen synthase 2 (liver) -3.34589
FGF9 fibroblast growth factor 9 -3.34589
TWIST1 twist family bHLH transcription factor 1 -3.34589
TRPV6 transient receptor potential cation channel, subfamily V, member 6 -3.34589
GCKR glucokinase (hexokinase 4) regulator -3.34589
WNT16 wingless-type MMTV integration site family, member 16 -3.34589
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B -3.34589
TNFRSF18 tumor necrosis factor receptor superfamily, member 18 -3.34589
ZFP28 ZFP28 zinc finger protein -3.34589
OR2A25 olfactory receptor, family 2, subfamily A, member 25 -3.34589
FETUB fetuin B -3.34589
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 -3.34589
UBE2V2 ubiquitin-conjugating enzyme E2 variant 2 -3.34589
SPAAR small regulatory polypeptide of amino acid response -3.34589
ALOXE3 arachidonate lipoxygenase 3 -3.34589
CLEC4G C-type lectin domain family 4, member G -3.34589
SMIM23 small integral membrane protein 23 -3.34589
KLF4 Kruppel-like factor 4 (gut) -3.34589
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled -3.34589
SHISA8 shisa family member 8 -3.34589
SRL sarcalumenin -3.34589
CSMD3 CUB and Sushi multiple domains 3 -3.27462
ECT2L epithelial cell transforming 2 like -3.23593
TPP1 tripeptidyl peptidase I -3.22945
VWDE von Willebrand factor D and EGF domains -3.22764
ETV6 ets variant 6 -3.04004
TM2D1 TM2 domain containing 1 -2.91751
SVOPL SVOP-like -2.72612
ARV1 ARV1 homolog (S. cerevisiae) -2.69704
DELE1 DAP3 binding cell death enhancer 1 -2.68714
SDE2 SDE2 telomere maintenance homolog (S. pombe) -2.65194
PCNX3 pecanex 3 -2.65194
ZNF816 zinc finger protein 816 -2.60528
CCL2 chemokine (C-C motif) ligand 2 -2.60528
PCDHB14 protocadherin beta 14 -2.57178
CARD14 caspase recruitment domain family, member 14 -2.57178
KCNJ13 potassium channel, inwardly rectifying subfamily J, member 13 -2.57178
AZU1 azurocidin 1 -2.57178
CNN1 calponin 1, basic, smooth muscle -2.56882
CKMT1B creatine kinase, mitochondrial 1B -2.55308
ZNF581 zinc finger protein 581 -2.53485
MICALL2 MICAL-like 2 -2.47666
ASPHD1 aspartate beta-hydroxylase domain containing 1 -2.47345
PCDHA11 protocadherin alpha 11 -2.45462
PRDM6 PR domain containing 6 -2.45462
SIRT1 sirtuin 1 -2.44156
STAG2 stromal antigen 2 -2.44122
TJP3 tight junction protein 3 -2.43476
OR10AG1 olfactory receptor, family 10, subfamily AG, member 1 -2.42295
RPGRIP1 retinitis pigmentosa GTPase regulator interacting protein 1 -2.42295
SLC4A3 solute carrier family 4 (anion exchanger), member 3 -2.42295
BTN1A1 butyrophilin, subfamily 1, member A1 -2.42295
BEND4 BEN domain containing 4 -2.38613
FLVCR1 feline leukemia virus subgroup C cellular receptor 1 -2.37725
SPATA1 spermatogenesis associated 1 -2.36154
IFT122 intraflagellar transport 122 -2.35434
SLA2 Src-like-adaptor 2 -2.34917
ACAP2 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 -2.34917
DKK2 dickkopf WNT signaling pathway inhibitor 2 -2.34917
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1 -2.3477
CTC1 CTS telomere maintenance complex component 1 -2.34404
CLSPN claspin -2.3303
POU3F1 POU class 3 homeobox 1 -2.32934
DUS3L dihydrouridine synthase 3-like (S. cerevisiae) -2.31698
THOC7 THO complex 7 -2.29004
HYCC2 hyccin PI4KA lipid kinase complex subunit 2 -2.27577
TAPBP TAP binding protein (tapasin) -2.23614
ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 -2.23614
SNCA synuclein, alpha (non A4 component of amyloid precursor) -2.22035
MATN1 matrilin 1, cartilage matrix protein -2.21709
ENO3 enolase 3 (beta, muscle) -2.21322
KCNG2 potassium channel, voltage gated modifier subfamily G, member 2 -2.20554
BEND7 BEN domain containing 7 -2.20506
SYBU syntabulin (syntaxin-interacting) -2.20308
FAIM Fas apoptotic inhibitory molecule -2.20277
NEURL1 neuralized E3 ubiquitin protein ligase 1 -2.20081
PTK7 protein tyrosine kinase 7 (inactive) -2.20056
ZNF880 zinc finger protein 880 -2.19776
CUX2 cut-like homeobox 2 -2.18046
KAT7 K(lysine) acetyltransferase 7 -2.16587
FAM156A family with sequence similarity 156, member A -2.12821
KAZN kazrin, periplakin interacting protein -2.115
PDLIM5 PDZ and LIM domain 5 -2.11202
FAM199X family with sequence similarity 199, X-linked -2.08484
MKRN1 makorin ring finger protein 1 -2.07238
FAAP100 FA core complex associated protein 100 -2.07222
TTF2 transcription termination factor, RNA polymerase II -2.06751
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 -2.0617
PIGP phosphatidylinositol glycan anchor biosynthesis, class P -2.05047
IGLON5 IgLON family member 5 -2.04536
TSPAN3 tetraspanin 3 -2.04536
ARFRP1 ADP-ribosylation factor related protein 1 -2.04066
ZBTB46 zinc finger and BTB domain containing 46 -2.03574
SCCPDH saccharopine dehydrogenase (putative) -2.00348