| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | ubiquitin-like with PHD and ring finger domains 1|This gene encodes a member of a subfamily of RING-finger type E3 ubiquitin ligases. The protein binds to specific DNA sequences, and recruits a histone deacetylase to regulate gene expression. Its expression peaks at late G1 phase and continues during G2 and M phases of the cell cycle. It plays a major role in the G1/S transition by regulating topoisomerase IIalpha and retinoblastoma gene expression, and functions in the p53-dependent DNA damage checkpoint. It is regarded as a hub protein for the integration of epigenetic information. This gene is up-regulated in various cancers, and it is therefore considered to be a therapeutic target. Multiple transcript variants encoding different isoforms have been found for this gene. A related pseudogene exists on chromosome 12. [provided by RefSeq, Feb 2014] (NCBI Entrez Gene Database, 29128) |
| External Link | https://ncbi.nlm.nih.gov/gene/29128 |
| Similar Terms | |
| Downloads & Tools |
499 genes differentially expressed following the UHRF1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LTF | lactotransferrin | 0.0164226 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0127312 |
| G0S2 | G0/G1 switch 2 | 0.0122717 |
| A2M | alpha-2-macroglobulin | 0.0107916 |
| PLBD1 | phospholipase B domain containing 1 | 0.0107581 |
| SYNGR3 | synaptogyrin 3 | 0.00973715 |
| MGP | matrix Gla protein | 0.00921573 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.0088848 |
| USP7 | ubiquitin specific peptidase 7 (herpes virus-associated) | 0.00886082 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | 0.00875087 |
| KRT15 | keratin 15, type I | 0.00874019 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi | 0.0087155 |
| MT1X | metallothionein 1X | 0.00870702 |
| PLTP | phospholipid transfer protein | 0.00866928 |
| PLAUR | plasminogen activator, urokinase receptor | 0.00865157 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | 0.00864115 |
| LCN2 | lipocalin 2 | 0.00861764 |
| CFB | complement factor B | 0.00857606 |
| FCER1G | Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide | 0.0084719 |
| DLK1 | delta-like 1 homolog (Drosophila) | 0.00842955 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | 0.0083637 |
| SLC25A14 | solute carrier family 25 (mitochondrial carrier, brain), member 14 | 0.00829633 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | 0.00819281 |
| MAGEA3 | melanoma antigen family A3 | 0.008167 |
| CHI3L2 | chitinase 3-like 2 | 0.00801707 |
| SYNE3 | spectrin repeat containing, nuclear envelope family member 3 | 0.0080007 |
| TSPYL5 | TSPY-like 5 | 0.00790521 |
| MDK | midkine (neurite growth-promoting factor 2) | 0.00789216 |
| PROM1 | prominin 1 | 0.00785568 |
| MLF1 | myeloid leukemia factor 1 | 0.00755088 |
| CCN2 | cellular communication network factor 2 | 0.00751662 |
| CYBA | cytochrome b-245, alpha polypeptide | 0.00736156 |
| C3 | complement component 3 | 0.00735397 |
| COL6A2 | collagen, type VI, alpha 2 | 0.00731144 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.00731095 |
| APOC1 | apolipoprotein C-I | 0.00729715 |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 | 0.00724064 |
| MMP7 | matrix metallopeptidase 7 | 0.00720132 |
| FCGRT | Fc fragment of IgG, receptor, transporter, alpha | 0.00715954 |
| POU2AF1 | POU class 2 associating factor 1 | 0.00713266 |
| TBCD | tubulin folding cofactor D | 0.00704131 |
| MXRA7 | matrix-remodelling associated 7 | 0.00703609 |
| NID2 | nidogen 2 (osteonidogen) | 0.00700337 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | 0.00700322 |
| PEG3 | paternally expressed 3 | 0.0069404 |
| COX7A1 | cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) | 0.00693132 |
| C1QB | complement component 1, q subcomponent, B chain | 0.00688129 |
| CPM | carboxypeptidase M | 0.00687861 |
| MMP9 | matrix metallopeptidase 9 | 0.00686079 |
| RGCC | regulator of cell cycle | 0.00683724 |
| ITM2A | integral membrane protein 2A | 0.00680032 |
| SYNM | synemin, intermediate filament protein | 0.00678328 |
| SLC43A3 | solute carrier family 43, member 3 | 0.00675781 |
| APOD | apolipoprotein D | 0.00673782 |
| CP | ceruloplasmin (ferroxidase) | 0.00672885 |
| PCOLCE | procollagen C-endopeptidase enhancer | 0.00671353 |
| EMP1 | epithelial membrane protein 1 | 0.00669891 |
| C1S | complement component 1, s subcomponent | 0.0066635 |
| KLHL21 | kelch-like family member 21 | 0.00660677 |
| LAPTM5 | lysosomal protein transmembrane 5 | 0.00652428 |
| FXYD5 | FXYD domain containing ion transport regulator 5 | 0.00650735 |
| NIBAN1 | niban apoptosis regulator 1 | 0.00650207 |
| RTN1 | reticulon 1 | 0.00648987 |
| CCL4 | chemokine (C-C motif) ligand 4 | 0.00646506 |
| MAGEA12 | melanoma antigen family A12 | 0.00643477 |
| ARMCX2 | armadillo repeat containing, X-linked 2 | 0.00642744 |
| PDLIM4 | PDZ and LIM domain 4 | 0.00641915 |
| NID1 | nidogen 1 | 0.00640157 |
| DEFB1 | defensin, beta 1 | 0.00635364 |
| SLA | Src-like-adaptor | 0.00634532 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.00633398 |
| SNX10 | sorting nexin 10 | 0.00632617 |
| ICAM2 | intercellular adhesion molecule 2 | 0.00630499 |
| MAGEH1 | melanoma antigen family H1 | 0.00629346 |
| GPRC5B | G protein-coupled receptor, class C, group 5, member B | 0.00627415 |
| NRIP3 | nuclear receptor interacting protein 3 | 0.00625707 |
| STAT5A | signal transducer and activator of transcription 5A | 0.00625394 |
| AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | 0.00624031 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.00623462 |
| COCH | cochlin | 0.00621657 |
| SFRP4 | secreted frizzled-related protein 4 | 0.00620036 |
| CTSK | cathepsin K | 0.00619393 |
| ATP6V0E2 | ATPase, H+ transporting V0 subunit e2 | 0.00618825 |
| ZSCAN18 | zinc finger and SCAN domain containing 18 | 0.00616109 |
| SIRT3 | sirtuin 3 | 0.00614103 |
| COL6A1 | collagen, type VI, alpha 1 | 0.00612063 |
| EFHD1 | EF-hand domain family, member D1 | 0.00610937 |
| SRPX | sushi-repeat containing protein, X-linked | 0.00604573 |
| SFRP1 | secreted frizzled-related protein 1 | 0.00594538 |
| MZB1 | marginal zone B and B1 cell-specific protein | 0.00593886 |
| NES | nestin | 0.00592229 |
| KRT14 | keratin 14, type I | 0.00592081 |
| APOBEC3B | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B | 0.00590739 |
| AEBP1 | AE binding protein 1 | 0.00586301 |
| CHP1 | calcineurin-like EF-hand protein 1 | 0.00585417 |
| IQCG | IQ motif containing G | 0.00584251 |
| MPP1 | membrane protein, palmitoylated 1, 55kDa | 0.00582567 |
| PLXDC1 | plexin domain containing 1 | 0.00582483 |
| RCAN1 | regulator of calcineurin 1 | 0.00580215 |
| TSPO | translocator protein (18kDa) | 0.00579255 |
| KLHL2 | kelch-like family member 2 | 0.00578718 |
| NPY | neuropeptide Y | 0.00575658 |
| PDE4DIP | phosphodiesterase 4D interacting protein | 0.00570843 |
| COL1A2 | collagen, type I, alpha 2 | 0.00569416 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | 0.00569215 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 | 0.00566734 |
| ASPN | asporin | 0.00564413 |
| SORBS2 | sorbin and SH3 domain containing 2 | 0.00564408 |
| TMEM131L | transmembrane 131 like | 0.00563084 |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta | 0.00562951 |
| AK1 | adenylate kinase 1 | 0.00558913 |
| GSDME | gasdermin E | 0.0055637 |
| PRKCA | protein kinase C, alpha | 0.00555304 |
| SLC17A9 | solute carrier family 17 (vesicular nucleotide transporter), member 9 | 0.00554943 |
| ARHGEF6 | Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 | 0.00553846 |
| KLF2 | Kruppel-like factor 2 | 0.0055292 |
| ACSL1 | acyl-CoA synthetase long-chain family member 1 | 0.00552847 |
| FCGR2A | Fc fragment of IgG, low affinity IIa, receptor (CD32) | 0.00550715 |
| GPX3 | glutathione peroxidase 3 | 0.0055052 |
| RGS10 | regulator of G-protein signaling 10 | 0.0055027 |
| CD8A | CD8a molecule | 0.0054913 |
| CES1 | carboxylesterase 1 | 0.00548379 |
| POSTN | periostin, osteoblast specific factor | 0.00546634 |
| INHBA | inhibin, beta A | 0.00544533 |
| BGN | biglycan | 0.00542847 |
| SIDT2 | SID1 transmembrane family, member 2 | 0.00542264 |
| AMPD3 | adenosine monophosphate deaminase 3 | 0.00541974 |
| LAMA2 | laminin, alpha 2 | 0.00537267 |
| PER1 | period circadian clock 1 | 0.00536806 |
| PDGFRL | platelet-derived growth factor receptor-like | 0.00536169 |
| CLEC11A | C-type lectin domain family 11, member A | 0.00535723 |
| TRPV2 | transient receptor potential cation channel, subfamily V, member 2 | 0.00533247 |
| STEAP3 | STEAP family member 3, metalloreductase | 0.00531176 |
| SLC39A4 | solute carrier family 39 (zinc transporter), member 4 | 0.0052942 |
| PLAAT3 | phospholipase A and acyltransferase 3 | 0.00529021 |
| CBS | cystathionine-beta-synthase | 0.00528902 |
| WFDC2 | WAP four-disulfide core domain 2 | 0.00526287 |
| GLUL | glutamate-ammonia ligase | 0.00525563 |
| TMSB15A | thymosin beta 15a | 0.00524791 |
| COL3A1 | collagen, type III, alpha 1 | 0.00522239 |
| KIF13B | kinesin family member 13B | 0.00521406 |
| TPST1 | tyrosylprotein sulfotransferase 1 | 0.00521 |
| CHPT1 | choline phosphotransferase 1 | 0.00520907 |
| IFITM2 | interferon induced transmembrane protein 2 | 0.00518864 |
| MIA | melanoma inhibitory activity | 0.00518761 |
| DCXR | dicarbonyl/L-xylulose reductase | 0.00518719 |
| TRPS1 | trichorhinophalangeal syndrome I | 0.0051756 |
| CD14 | CD14 molecule | 0.00517369 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) | 0.00516104 |
| ANPEP | alanyl (membrane) aminopeptidase | 0.00514751 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.00514605 |
| SH2B3 | SH2B adaptor protein 3 | 0.00507305 |
| BAMBI | BMP and activin membrane-bound inhibitor | 0.00507192 |
| PRPF8 | pre-mRNA processing factor 8 | 0.00506839 |
| BEX4 | brain expressed, X-linked 4 | 0.0050669 |
| TSPAN8 | tetraspanin 8 | 0.00506661 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | 0.00503536 |
| NBL1 | neuroblastoma 1, DAN family BMP antagonist | 0.00502265 |
| MICAL1 | microtubule associated monooxygenase, calponin and LIM domain containing 1 | 0.00499037 |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 | 0.00498131 |
| HCLS1 | hematopoietic cell-specific Lyn substrate 1 | 0.00495655 |
| C2 | complement component 2 | 0.00495571 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.00493858 |
| VWA1 | von Willebrand factor A domain containing 1 | 0.00493715 |
| RARRES3 | retinoic acid receptor responder (tazarotene induced) 3 | 0.00493386 |
| TPPP3 | tubulin polymerization-promoting protein family member 3 | 0.00491256 |
| COL6A3 | collagen, type VI, alpha 3 | 0.00490634 |
| RRAGD | Ras-related GTP binding D | 0.00489546 |
| RGS4 | regulator of G-protein signaling 4 | 0.00489279 |
| MXRA5 | matrix-remodelling associated 5 | 0.00488902 |
| GIMAP5 | GTPase, IMAP family member 5 | 0.00488489 |
| KDELR3 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 | 0.00488174 |
| MAGED1 | melanoma antigen family D1 | 0.00487741 |
| GSAP | gamma-secretase activating protein | 0.00487153 |
| ITGB2 | integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) | 0.00487035 |
| WDR7 | WD repeat domain 7 | 0.00486589 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.00486256 |
| CHD7 | chromodomain helicase DNA binding protein 7 | 0.0048426 |
| CTSZ | cathepsin Z | 0.00479846 |
| NOTCH3 | notch 3 | 0.00478904 |
| IL1B | interleukin 1, beta | 0.00476792 |
| SERPING1 | serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 | 0.00475346 |
| C3AR1 | complement component 3a receptor 1 | 0.0047495 |
| C5AR1 | complement component 5a receptor 1 | 0.00474859 |
| H2AX | H2A.X variant histone | 0.00474251 |
| TNS1 | tensin 1 | 0.00473843 |
| C10ORF10 | chromosome 10 open reading frame 10 | 0.00473716 |
| ZIC1 | Zic family member 1 | 0.00473493 |
| GEM | GTP binding protein overexpressed in skeletal muscle | 0.00473376 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.00473075 |
| OLFML2B | olfactomedin-like 2B | 0.00472549 |
| NIPSNAP2 | nipsnap homolog 2 | 0.00470724 |
| HAMP | hepcidin antimicrobial peptide | 0.0047055 |
| STC1 | stanniocalcin 1 | 0.00470479 |
| GMFG | glia maturation factor, gamma | 0.00470254 |
| VWA5A | von Willebrand factor A domain containing 5A | 0.00469921 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | 0.00468016 |
| TBC1D1 | TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1 | 0.00466773 |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta | 0.00465876 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | 0.00463088 |
| IGLL1 | immunoglobulin lambda-like polypeptide 1 | 0.00461902 |
| YBX3 | Y box binding protein 3 | 0.00461173 |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B | 0.00461044 |
| COL5A2 | collagen, type V, alpha 2 | 0.00460758 |
| TMEM255A | transmembrane protein 255A | 0.00460166 |
| SVIL | supervillin | 0.00459552 |
| LEF1 | lymphoid enhancer-binding factor 1 | 0.0045932 |
| TMOD1 | tropomodulin 1 | 0.00458087 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.00457821 |
| SORBS1 | sorbin and SH3 domain containing 1 | 0.00457405 |
| MT1E | metallothionein 1E | 0.00456563 |
| ATRN | attractin | 0.00456422 |
| PITX3 | paired-like homeodomain 3 | 0.00453893 |
| ITGAM | integrin, alpha M (complement component 3 receptor 3 subunit) | 0.00453126 |
| ISLR | immunoglobulin superfamily containing leucine-rich repeat | 0.00452739 |
| CFH | complement factor H | 0.0045182 |
| MYH10 | myosin, heavy chain 10, non-muscle | 0.00451381 |
| C2CD5 | C2 calcium-dependent domain containing 5 | 0.00451304 |
| MAL | mal, T-cell differentiation protein | 0.00450701 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0045029 |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain | 0.00450258 |
| TRIP6 | thyroid hormone receptor interactor 6 | 0.00449092 |
| FAM171A1 | family with sequence similarity 171, member A1 | 0.00448113 |
| EIF4A3 | eukaryotic translation initiation factor 4A3 | 0.00447443 |
| CAPG | capping protein (actin filament), gelsolin-like | 0.00447158 |
| MAZ | MYC-associated zinc finger protein (purine-binding transcription factor) | 0.00446941 |
| PFN2 | profilin 2 | 0.00446631 |
| LILRB4 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4 | 0.00446304 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | 0.0044604 |
| RTN3 | reticulon 3 | 0.00445648 |
| ACADVL | acyl-CoA dehydrogenase, very long chain | 0.00443607 |
| PADI2 | peptidyl arginine deiminase, type II | 0.00443059 |
| CD81 | CD81 molecule | 0.00442636 |
| SELPLG | selectin P ligand | 0.00442359 |
| GIMAP6 | GTPase, IMAP family member 6 | 0.00442103 |
| CDK2AP1 | cyclin-dependent kinase 2 associated protein 1 | 0.00441963 |
| HSPA1A | heat shock 70kDa protein 1A | 0.0044167 |
| MT1F | metallothionein 1F | 0.0044057 |
| IQCK | IQ motif containing K | 0.00439318 |
| RUNX1 | runt-related transcription factor 1 | 0.00439225 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) | 0.00438491 |
| APOC2 | apolipoprotein C-II | 0.00438483 |
| HMGA1 | high mobility group AT-hook 1 | 0.00438004 |
| HAUS4 | HAUS augmin-like complex, subunit 4 | 0.00437636 |
| CHRDL1 | chordin-like 1 | 0.00437592 |
| SOX10 | SRY (sex determining region Y)-box 10 | 0.00437389 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.00436434 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | 0.00435644 |
| SCPEP1 | serine carboxypeptidase 1 | 0.00435546 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0190066 |
| MAP7 | microtubule-associated protein 7 | -0.0160668 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -0.0147809 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | -0.0136376 |
| HBB | hemoglobin, beta | -0.0133436 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0112273 |
| ZDHHC6 | zinc finger, DHHC-type containing 6 | -0.00997258 |
| EPHB2 | EPH receptor B2 | -0.00971283 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | -0.0095807 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | -0.00906418 |
| NVL | nuclear VCP-like | -0.00824384 |
| SCGB1D2 | secretoglobin, family 1D, member 2 | -0.00810821 |
| GJA1 | gap junction protein, alpha 1, 43kDa | -0.00803398 |
| TIMM9 | translocase of inner mitochondrial membrane 9 homolog (yeast) | -0.00801098 |
| RGS13 | regulator of G-protein signaling 13 | -0.00787713 |
| PRDX2 | peroxiredoxin 2 | -0.00784272 |
| HOXB6 | homeobox B6 | -0.00770261 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | -0.00765286 |
| SPINK2 | serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) | -0.00763381 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 | -0.00755224 |
| PGAM1 | phosphoglycerate mutase 1 (brain) | -0.00754138 |
| SH3YL1 | SH3 and SYLF domain containing 1 | -0.00753886 |
| SLC38A1 | solute carrier family 38, member 1 | -0.00747106 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | -0.00732098 |
| DACH1 | dachshund family transcription factor 1 | -0.00726639 |
| TOX3 | TOX high mobility group box family member 3 | -0.00706462 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.00682528 |
| FABP1 | fatty acid binding protein 1, liver | -0.00668561 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) | -0.00663946 |
| MPO | myeloperoxidase | -0.0065603 |
| SRP9 | signal recognition particle 9kDa | -0.00649792 |
| KRT20 | keratin 20, type I | -0.0064595 |
| ACKR3 | atypical chemokine receptor 3 | -0.006444 |
| SEMA6A | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A | -0.00632489 |
| CCNB1 | cyclin B1 | -0.00629083 |
| MYCN | v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog | -0.00628833 |
| MS4A1 | membrane-spanning 4-domains, subfamily A, member 1 | -0.0062675 |
| PAK1 | p21 protein (Cdc42/Rac)-activated kinase 1 | -0.00625857 |
| ARNT2 | aryl-hydrocarbon receptor nuclear translocator 2 | -0.00606345 |
| ARMT1 | acidic residue methyltransferase 1 | -0.00603722 |
| AMMECR1 | Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1 | -0.00596382 |
| SLC26A3 | solute carrier family 26 (anion exchanger), member 3 | -0.00595182 |
| CPA3 | carboxypeptidase A3 (mast cell) | -0.00589706 |
| PHACTR2 | phosphatase and actin regulator 2 | -0.00587373 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.00581108 |
| CXADR | coxsackie virus and adenovirus receptor | -0.0058077 |
| TDP2 | tyrosyl-DNA phosphodiesterase 2 | -0.00575193 |
| MID1 | midline 1 | -0.00569042 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | -0.00568714 |
| DUSP11 | dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) | -0.00568109 |
| HOPX | HOP homeobox | -0.00567358 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 | -0.00565967 |
| COL4A6 | collagen, type IV, alpha 6 | -0.00563498 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.00562452 |
| HNRNPL | heterogeneous nuclear ribonucleoprotein L | -0.00561641 |
| NDNF | neuron-derived neurotrophic factor | -0.00560524 |
| NUTF2 | nuclear transport factor 2 | -0.00559175 |
| SLC17A3 | solute carrier family 17 (organic anion transporter), member 3 | -0.00558873 |
| MN1 | meningioma (disrupted in balanced translocation) 1 | -0.00558769 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.00554901 |
| FOXF1 | forkhead box F1 | -0.00554636 |
| GPR87 | G protein-coupled receptor 87 | -0.00551382 |
| COL4A5 | collagen, type IV, alpha 5 | -0.00550991 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | -0.00549083 |
| TPD52L1 | tumor protein D52-like 1 | -0.00548675 |
| GUSBP3 | glucuronidase, beta pseudogene 3 | -0.00542394 |
| CNIH4 | cornichon family AMPA receptor auxiliary protein 4 | -0.00540987 |
| TXN | thioredoxin | -0.00538496 |
| COMMD8 | COMM domain containing 8 | -0.00536508 |
| HOXB5 | homeobox B5 | -0.00535339 |
| ATG3 | autophagy related 3 | -0.00533757 |
| DSE | dermatan sulfate epimerase | -0.00533057 |
| TNFSF4 | tumor necrosis factor (ligand) superfamily, member 4 | -0.00532304 |
| SPINK4 | serine peptidase inhibitor, Kazal type 4 | -0.00529913 |
| NPR3 | natriuretic peptide receptor 3 | -0.00529819 |
| COL4A3 | collagen, type IV, alpha 3 (Goodpasture antigen) | -0.00529082 |
| CD46 | CD46 molecule, complement regulatory protein | -0.00527469 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.00526654 |
| CDH17 | cadherin 17, LI cadherin (liver-intestine) | -0.00525602 |
| PKP2 | plakophilin 2 | -0.00522776 |
| NOX1 | NADPH oxidase 1 | -0.00521671 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | -0.005216 |
| MUC2 | mucin 2, oligomeric mucus/gel-forming | -0.00519145 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.00518949 |
| RAB32 | RAB32, member RAS oncogene family | -0.00517181 |
| DENND1B | DENN/MADD domain containing 1B | -0.00516746 |
| EZR | ezrin | -0.00516516 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | -0.00515672 |
| MPHOSPH8 | M-phase phosphoprotein 8 | -0.00512036 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -0.00511277 |
| SLC38A2 | solute carrier family 38, member 2 | -0.00508893 |
| THBS1 | thrombospondin 1 | -0.00506086 |
| CCN3 | cellular communication network factor 3 | -0.0050592 |
| CGA | glycoprotein hormones, alpha polypeptide | -0.00505036 |
| FAM162A | family with sequence similarity 162, member A | -0.00504041 |
| C7 | complement component 7 | -0.00500737 |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 | -0.00499638 |
| UGT2B17 | UDP glucuronosyltransferase 2 family, polypeptide B17 | -0.00499137 |
| GSTA1 | glutathione S-transferase alpha 1 | -0.00498116 |
| CALD1 | caldesmon 1 | -0.00496059 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.00494902 |
| NDUFA4 | NDUFA4, mitochondrial complex associated | -0.00493213 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | -0.00492543 |
| DAAM1 | dishevelled associated activator of morphogenesis 1 | -0.00492286 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 | -0.00492162 |
| IL20RA | interleukin 20 receptor, alpha | -0.00491843 |
| ELOB | elongin B | -0.00490419 |
| EPB41L4B | erythrocyte membrane protein band 4.1 like 4B | -0.00489851 |
| IMPA2 | inositol(myo)-1(or 4)-monophosphatase 2 | -0.00489772 |
| SERINC5 | serine incorporator 5 | -0.00488021 |
| FZD5 | frizzled class receptor 5 | -0.00485964 |
| PPBP | pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) | -0.00484626 |
| ESRP1 | epithelial splicing regulatory protein 1 | -0.00482974 |
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 | -0.00482807 |
| DTX4 | deltex 4, E3 ubiquitin ligase | -0.00481599 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 | -0.00481153 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.00479921 |
| HMGCS2 | 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) | -0.00479734 |
| PSMA2 | proteasome (prosome, macropain) subunit, alpha type, 2 | -0.00479138 |
| PEX3 | peroxisomal biogenesis factor 3 | -0.00478534 |
| HOXB7 | homeobox B7 | -0.00478293 |
| RNF125 | ring finger protein 125, E3 ubiquitin protein ligase | -0.00477953 |
| TIGAR | TP53 induced glycolysis regulatory phosphatase | -0.00477521 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 | -0.00476929 |
| CLCA4 | chloride channel accessory 4 | -0.0047347 |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) | -0.00471429 |
| FZD6 | frizzled class receptor 6 | -0.00470322 |
| DKFZP586I1420 | uncharacterized protein DKFZp586I1420 | -0.00467674 |
| GPA33 | glycoprotein A33 (transmembrane) | -0.00467434 |
| FLRT3 | fibronectin leucine rich transmembrane protein 3 | -0.00465366 |
| CELSR1 | cadherin, EGF LAG seven-pass G-type receptor 1 | -0.00461859 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.00456776 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.00456663 |
| RBBP7 | retinoblastoma binding protein 7 | -0.00456635 |
| ZNF611 | zinc finger protein 611 | -0.00455589 |
| PLCB4 | phospholipase C, beta 4 | -0.00452678 |
| TMPRSS4 | transmembrane protease, serine 4 | -0.00452565 |
| ORC1 | origin recognition complex, subunit 1 | -0.00452143 |
| CSTA | cystatin A (stefin A) | -0.00451439 |
| HINT1 | histidine triad nucleotide binding protein 1 | -0.00451316 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | -0.00450475 |
| SLC27A2 | solute carrier family 27 (fatty acid transporter), member 2 | -0.00450426 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | -0.00449891 |
| FERMT1 | fermitin family member 1 | -0.00449079 |
| GPX2 | glutathione peroxidase 2 | -0.00448113 |
| TSPAN13 | tetraspanin 13 | -0.00447755 |
| UQCR11 | ubiquinol-cytochrome c reductase, complex III subunit XI | -0.00446054 |
| HMOX1 | heme oxygenase 1 | -0.00446017 |
| SCD5 | stearoyl-CoA desaturase 5 | -0.00443895 |
| VPS35 | vacuolar protein sorting 35 homolog (S. cerevisiae) | -0.00442143 |
| PPA1 | pyrophosphatase (inorganic) 1 | -0.00441549 |
| ADAT1 | adenosine deaminase, tRNA-specific 1 | -0.00441523 |
| AP5M1 | adaptor-related protein complex 5, mu 1 subunit | -0.00440801 |
| IL18 | interleukin 18 | -0.00440531 |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 | -0.00440141 |
| CCNG2 | cyclin G2 | -0.00440114 |
| SDC4 | syndecan 4 | -0.00440105 |
| MCL1 | myeloid cell leukemia 1 | -0.00440077 |
| BANK1 | B-cell scaffold protein with ankyrin repeats 1 | -0.00439214 |
| CANX | calnexin | -0.00439069 |
| SLC25A46 | solute carrier family 25, member 46 | -0.00438068 |
| UPK1B | uroplakin 1B | -0.00437313 |
| CADM1 | cell adhesion molecule 1 | -0.00437158 |
| GUCY2C | guanylate cyclase 2C | -0.00436181 |
| MATN2 | matrilin 2 | -0.00435638 |
| PDZK1 | PDZ domain containing 1 | -0.00434518 |
| REL | v-rel avian reticuloendotheliosis viral oncogene homolog | -0.00434284 |
| MEP1A | meprin A, alpha (PABA peptide hydrolase) | -0.00433897 |
| AOX1 | aldehyde oxidase 1 | -0.00433605 |
| TSC22D1 | TSC22 domain family, member 1 | -0.0043295 |
| CCND2 | cyclin D2 | -0.00432439 |
| MTERF3 | mitochondrial transcription termination factor 3 | -0.00432009 |
| DPP8 | dipeptidyl-peptidase 8 | -0.00431951 |
| CHN1 | chimerin 1 | -0.00430907 |
| CST6 | cystatin E/M | -0.00428762 |
| CKS2 | CDC28 protein kinase regulatory subunit 2 | -0.00427327 |
| MTCL1 | microtubule crosslinking factor 1 | -0.0042653 |
| ALDH1B1 | aldehyde dehydrogenase 1 family, member B1 | -0.00425969 |
| ACTR10 | actin-related protein 10 homolog (S. cerevisiae) | -0.00425637 |
| CPS1 | carbamoyl-phosphate synthase 1, mitochondrial | -0.00425386 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | -0.00425243 |
| FAM13B | family with sequence similarity 13, member B | -0.00424209 |
| LRRC19 | leucine rich repeat containing 19 | -0.00423942 |
| TNS3 | tensin 3 | -0.00422994 |
| RPL36 | ribosomal protein L36 | -0.00421522 |
| ZNF721 | zinc finger protein 721 | -0.00421186 |
| CYP17A1 | cytochrome P450, family 17, subfamily A, polypeptide 1 | -0.00419977 |
| FOXF2 | forkhead box F2 | -0.0041963 |
| GTF2H2B | general transcription factor IIH, polypeptide 2B (pseudogene) | -0.00418076 |
| STX3 | syntaxin 3 | -0.0041729 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.00416742 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha | -0.00415931 |
| COMMD10 | COMM domain containing 10 | -0.00414864 |
| COA4 | cytochrome c oxidase assembly factor 4 homolog (S. cerevisiae) | -0.0041381 |
| AOC1 | amine oxidase, copper containing 1 | -0.00412498 |
| HAL | histidine ammonia-lyase | -0.00412466 |
| ERAP2 | endoplasmic reticulum aminopeptidase 2 | -0.0041244 |
| CYP39A1 | cytochrome P450, family 39, subfamily A, polypeptide 1 | -0.00412364 |
| CLC | Charcot-Leyden crystal galectin | -0.00411519 |
| AKAP11 | A kinase (PRKA) anchor protein 11 | -0.00409911 |
| TRAF5 | TNF receptor-associated factor 5 | -0.00408346 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 | -0.00408226 |
| OSBPL10 | oxysterol binding protein-like 10 | -0.00407521 |
| ZNF160 | zinc finger protein 160 | -0.00407356 |
| OLFM1 | olfactomedin 1 | -0.00407267 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | -0.00407047 |
| ATP5MG | ATP synthase membrane subunit g | -0.00406806 |
| ZNF200 | zinc finger protein 200 | -0.00406249 |
| CNOT8 | CCR4-NOT transcription complex, subunit 8 | -0.004055 |
| MRPL42 | mitochondrial ribosomal protein L42 | -0.00404589 |
| CYP2J2 | cytochrome P450, family 2, subfamily J, polypeptide 2 | -0.00404512 |
| PTGER4 | prostaglandin E receptor 4 (subtype EP4) | -0.00404199 |
| EREG | epiregulin | -0.00403834 |
| PFDN4 | prefoldin subunit 4 | -0.00403162 |
| UPK1A | uroplakin 1A | -0.00402704 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.00402503 |
| PSG5 | pregnancy specific beta-1-glycoprotein 5 | -0.0040249 |
| PERP | PERP, TP53 apoptosis effector | -0.00402367 |
| AHSP | alpha hemoglobin stabilizing protein | -0.00400925 |
| ACE2 | angiotensin I converting enzyme 2 | -0.00400688 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | -0.00400555 |
| PAWR | PRKC, apoptosis, WT1, regulator | -0.00400396 |
| CPOX | coproporphyrinogen oxidase | -0.00399968 |
| ATP6V1G1 | ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1 | -0.00399938 |
| HIST1H2BD | histone cluster 1, H2bd | -0.00399697 |
| COX7B | cytochrome c oxidase subunit VIIb | -0.0039905 |
| TMEM63A | transmembrane protein 63A | -0.00397573 |
| OLA1 | Obg-like ATPase 1 | -0.00395961 |
| STK17A | serine/threonine kinase 17a | -0.00395506 |
| PSMA3 | proteasome (prosome, macropain) subunit, alpha type, 3 | -0.00395024 |
| HAVCR1 | hepatitis A virus cellular receptor 1 | -0.0039467 |
| SLC34A2 | solute carrier family 34 (type II sodium/phosphate cotransporter), member 2 | -0.00393427 |
| APEX1 | APEX nuclease (multifunctional DNA repair enzyme) 1 | -0.00392581 |
| A1CF | APOBEC1 complementation factor | -0.00391893 |
| ATP5F1C | ATP synthase F1 subunit gamma | -0.00390729 |
| PPA2 | pyrophosphatase (inorganic) 2 | -0.00390454 |
| CYP2B6 | cytochrome P450, family 2, subfamily B, polypeptide 6 | -0.00390144 |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) | -0.00388791 |
| MRPL13 | mitochondrial ribosomal protein L13 | -0.00388367 |
| SORD | sorbitol dehydrogenase | -0.00388072 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.00387851 |
| ACP1 | acid phosphatase 1, soluble | -0.00387761 |
| KRCC1 | lysine-rich coiled-coil 1 | -0.00386882 |
| EAF2 | ELL associated factor 2 | -0.00386242 |
| FAM120A | family with sequence similarity 120A | -0.00385985 |
| NEBL | nebulette | -0.00385911 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.00385649 |
| CA2 | carbonic anhydrase II | -0.00384796 |
| CA4 | carbonic anhydrase IV | -0.00383899 |
| PIP5K1B | phosphatidylinositol-4-phosphate 5-kinase, type I, beta | -0.00383419 |
