| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | ULK-101 perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the ULK-101_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0879919 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0767753 |
| AREG | amphiregulin | 0.062007 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0569654 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0479267 |
| VMP1 | vacuole membrane protein 1 | 0.0438539 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0435384 |
| INTS6 | integrator complex subunit 6 | 0.0419306 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0390172 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0355068 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0346376 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0343218 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0340168 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0314974 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0314277 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0312077 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0310748 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0306539 |
| IPO7 | importin 7 | 0.0304796 |
| EGR1 | early growth response 1 | 0.030391 |
| TXNRD1 | thioredoxin reductase 1 | 0.0302079 |
| DENND5A | DENN/MADD domain containing 5A | 0.0300094 |
| JMJD1C | jumonji domain containing 1C | 0.030009 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0293215 |
| ASPH | aspartate beta-hydroxylase | 0.0292839 |
| YAP1 | Yes-associated protein 1 | 0.0290513 |
| ADIPOR2 | adiponectin receptor 2 | 0.028111 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | 0.0280529 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0258833 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.025737 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0250763 |
| RRM2 | ribonucleotide reductase M2 | 0.0244313 |
| FTL | ferritin, light polypeptide | 0.0243373 |
| PCBP2 | poly(rC) binding protein 2 | 0.0241097 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0235665 |
| RAPGEF6 | Rap guanine nucleotide exchange factor (GEF) 6 | 0.0235326 |
| RPL7 | ribosomal protein L7 | 0.0235204 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0231817 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0228233 |
| LRRC23 | leucine rich repeat containing 23 | 0.0228098 |
| YBX1 | Y box binding protein 1 | 0.0216711 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0211695 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0207928 |
| CAMKMT | calmodulin-lysine N-methyltransferase | 0.0206568 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0205351 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0196806 |
| SQSTM1 | sequestosome 1 | 0.0195282 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0193532 |
| C6ORF62 | chromosome 6 open reading frame 62 | 0.0192282 |
| VIM | vimentin | 0.0189503 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0188682 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.0188433 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0187053 |
| RPLP0 | ribosomal protein, large, P0 | 0.018703 |
| RCOR1 | REST corepressor 1 | 0.0185361 |
| RACK1 | receptor for activated C kinase 1 | 0.0183921 |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | 0.0183443 |
| ERBIN | erbb2 interacting protein | 0.0183147 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0181163 |
| HOMER1 | homer scaffolding protein 1 | 0.0178833 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0178158 |
| HMGA2 | high mobility group AT-hook 2 | 0.0175124 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0173167 |
| TAOK1 | TAO kinase 1 | 0.0172189 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0171371 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0169269 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | 0.0168253 |
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 | 0.0167393 |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit | 0.0167162 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0165706 |
| TNRC6B | trinucleotide repeat containing 6B | 0.016567 |
| PGK1 | phosphoglycerate kinase 1 | 0.0161342 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0161111 |
| MED13 | mediator complex subunit 13 | 0.0161061 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0159192 |
| UBC | ubiquitin C | 0.0158779 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0157985 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0157411 |
| VPS8 | vacuolar protein sorting 8 homolog (S. cerevisiae) | 0.0155511 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0153128 |
| SCFD1 | sec1 family domain containing 1 | 0.0150097 |
| REL | v-rel avian reticuloendotheliosis viral oncogene homolog | 0.0148667 |
| INTS4 | integrator complex subunit 4 | 0.0148037 |
| ABI2 | abl-interactor 2 | 0.0143674 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0143634 |
| USP15 | ubiquitin specific peptidase 15 | 0.0143001 |
| USP47 | ubiquitin specific peptidase 47 | 0.0142284 |
| AGO3 | argonaute RISC catalytic component 3 | 0.014173 |
| MAP3K13 | mitogen-activated protein kinase kinase kinase 13 | 0.0141111 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.014105 |
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit | 0.014067 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0140044 |
| NEK7 | NIMA-related kinase 7 | 0.0139972 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | 0.0139194 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0139116 |
| RPL32 | ribosomal protein L32 | 0.0139073 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0137991 |
| SERINC1 | serine incorporator 1 | 0.0137695 |
| RLF | rearranged L-myc fusion | 0.0137479 |
| TEX14 | testis expressed 14 | 0.013679 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NLGN1 | neuroligin 1 | -0.185949 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0772438 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.0604484 |
| PTMA | prothymosin, alpha | -0.058374 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0574863 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0565828 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0553561 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | -0.0519566 |
| TMSB10 | thymosin beta 10 | -0.0518396 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.0439945 |
| CELF2 | CUGBP, Elav-like family member 2 | -0.0438081 |
| MKI67 | marker of proliferation Ki-67 | -0.0413839 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0402577 |
| DST | dystonin | -0.0395017 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0380287 |
| TENM3 | teneurin transmembrane protein 3 | -0.0377371 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0373215 |
| NR5A2 | nuclear receptor subfamily 5, group A, member 2 | -0.0362433 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0330781 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0330565 |
| CENPF | centromere protein F, 350/400kDa | -0.0327391 |
| NEBL | nebulette | -0.0317587 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0316538 |
| MMP12 | matrix metallopeptidase 12 | -0.0312301 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | -0.0310047 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0309497 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | -0.0308609 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0302736 |
| CUBN | cubilin (intrinsic factor-cobalamin receptor) | -0.0301596 |
| LARP1 | La ribonucleoprotein domain family, member 1 | -0.0294835 |
| NHSL1 | NHS-like 1 | -0.0285957 |
| RPL35A | ribosomal protein L35a | -0.0283067 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0273653 |
| PCDH7 | protocadherin 7 | -0.0272737 |
| RPL37A | ribosomal protein L37a | -0.0268075 |
| SYT1 | synaptotagmin I | -0.0266125 |
| KIF18B | kinesin family member 18B | -0.0263756 |
| CCND1 | cyclin D1 | -0.0262001 |
| BCHE | butyrylcholinesterase | -0.0261714 |
| TMEM41B | transmembrane protein 41B | -0.0258417 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0256599 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0252495 |
| CLPTM1L | CLPTM1-like | -0.0252488 |
| OLR1 | oxidized low density lipoprotein (lectin-like) receptor 1 | -0.0248388 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | -0.024102 |
| MAP1B | microtubule-associated protein 1B | -0.0240572 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | -0.023814 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0237071 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0236768 |
| CMIP | c-Maf inducing protein | -0.0234648 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0234279 |
| PTMS | parathymosin | -0.0228792 |
| PDGFC | platelet derived growth factor C | -0.0225306 |
| TGM2 | transglutaminase 2 | -0.0223201 |
| PRR11 | proline rich 11 | -0.0217089 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0216687 |
| CLDN1 | claudin 1 | -0.0216056 |
| LMO7 | LIM domain 7 | -0.0209419 |
| P3H2 | prolyl 3-hydroxylase 2 | -0.0205874 |
| CENPE | centromere protein E, 312kDa | -0.0202012 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0201677 |
| AXIN2 | axin 2 | -0.0199568 |
| FSTL5 | follistatin-like 5 | -0.0199009 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0195088 |
| CALR | calreticulin | -0.0193513 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | -0.0190948 |
| ZNF804A | zinc finger protein 804A | -0.0189144 |
| HMGA1 | high mobility group AT-hook 1 | -0.0187102 |
| EHBP1 | EH domain binding protein 1 | -0.0187092 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.018658 |
| HLTF | helicase-like transcription factor | -0.0184372 |
| CDK6 | cyclin-dependent kinase 6 | -0.0181395 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.0178983 |
| TMEM131 | transmembrane protein 131 | -0.0177574 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0176013 |
| TUBB | tubulin, beta class I | -0.0175187 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0174138 |
| CCN2 | cellular communication network factor 2 | -0.017348 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.017136 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0168751 |
| TWSG1 | twisted gastrulation BMP signaling modulator 1 | -0.0168059 |
| CRISPLD1 | cysteine-rich secretory protein LCCL domain containing 1 | -0.0167863 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.016771 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0167596 |
| CCT6A | chaperonin containing TCP1, subunit 6A (zeta 1) | -0.0166101 |
| XPO1 | exportin 1 | -0.0165914 |
| ANXA1 | annexin A1 | -0.0165585 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | -0.0165276 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0165124 |
| GCG | glucagon | -0.0165124 |
| ATP9A | ATPase, class II, type 9A | -0.0163888 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | -0.0162388 |
| RPS21 | ribosomal protein S21 | -0.0161998 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.0161761 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0161622 |
| TPR | translocated promoter region, nuclear basket protein | -0.0160501 |
| AFG3L2 | AFG3-like AAA ATPase 2 | -0.0159211 |
| THSD7A | thrombospondin, type I, domain containing 7A | -0.0158731 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0156593 |
| SMC3 | structural maintenance of chromosomes 3 | -0.0155668 |
