| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | ULK-101 perturbation in A498 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the ULK-101_A498 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EXT1 | exostosin glycosyltransferase 1 | 0.110158 |
| FNDC3B | fibronectin type III domain containing 3B | 0.082218 |
| GPC6 | glypican 6 | 0.0719759 |
| FRMD4A | FERM domain containing 4A | 0.069427 |
| NAV2 | neuron navigator 2 | 0.0569219 |
| KYNU | kynureninase | 0.048333 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0481379 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0471987 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0444151 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0413025 |
| CD44 | CD44 molecule (Indian blood group) | 0.041267 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0412661 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0412127 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.039346 |
| SMAD3 | SMAD family member 3 | 0.0387331 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0377082 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0361045 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0339726 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0337579 |
| RAI14 | retinoic acid induced 14 | 0.0334932 |
| RNF213 | ring finger protein 213 | 0.0332218 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0327074 |
| MYOF | myoferlin | 0.0324239 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0315776 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0307881 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0299796 |
| EHBP1 | EH domain binding protein 1 | 0.0291959 |
| CANX | calnexin | 0.0290207 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0290117 |
| RIGI | RNA sensor RIG-I | 0.0287901 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0285761 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | 0.0282048 |
| CA12 | carbonic anhydrase XII | 0.0281941 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0280592 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0280102 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0275554 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0273887 |
| MYO1E | myosin IE | 0.0269848 |
| OSMR | oncostatin M receptor | 0.026811 |
| EFNA5 | ephrin-A5 | 0.0267366 |
| ATP13A3 | ATPase type 13A3 | 0.0267054 |
| TPM3 | tropomyosin 3 | 0.0263365 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0262698 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0260215 |
| VCL | vinculin | 0.0259944 |
| TXNRD1 | thioredoxin reductase 1 | 0.0259699 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0257986 |
| COG5 | component of oligomeric golgi complex 5 | 0.0256589 |
| EGFR | epidermal growth factor receptor | 0.0256354 |
| MX1 | MX dynamin-like GTPase 1 | 0.0254352 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.025375 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0253262 |
| ASPH | aspartate beta-hydroxylase | 0.0253088 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.025167 |
| TUT7 | terminal uridylyl transferase 7 | 0.024884 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | 0.0245258 |
| GOLGB1 | golgin B1 | 0.024259 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.023927 |
| VMP1 | vacuole membrane protein 1 | 0.0237015 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0234567 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0223953 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0222879 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0222752 |
| RND3 | Rho family GTPase 3 | 0.0222001 |
| DST | dystonin | 0.0221924 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0218541 |
| EXOC4 | exocyst complex component 4 | 0.0216634 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0214052 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0210775 |
| CTBP2 | C-terminal binding protein 2 | 0.0208493 |
| ANXA5 | annexin A5 | 0.0207163 |
| RUNX1 | runt-related transcription factor 1 | 0.0206885 |
| JAK1 | Janus kinase 1 | 0.0205777 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0203407 |
| FAT1 | FAT atypical cadherin 1 | 0.0201506 |
| IFI44L | interferon-induced protein 44-like | 0.0199673 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0199645 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0198538 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0198463 |
| SPAG9 | sperm associated antigen 9 | 0.019742 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.019534 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0194716 |
| HDAC9 | histone deacetylase 9 | 0.019414 |
| CADPS2 | Ca++-dependent secretion activator 2 | 0.0193967 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.019396 |
| CALU | calumenin | 0.0193284 |
| MSR1 | macrophage scavenger receptor 1 | 0.0191648 |
| SPIDR | scaffolding protein involved in DNA repair | 0.0190728 |
| SLC41A2 | solute carrier family 41 (magnesium transporter), member 2 | 0.0188621 |
| BLZF1 | basic leucine zipper nuclear factor 1 | 0.0188523 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0188444 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.018741 |
| NUP98 | nucleoporin 98kDa | 0.0186746 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0186213 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | 0.0186173 |
| SEPTIN9 | septin 9 | 0.0184424 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0182376 |
| TRAM1 | translocation associated membrane protein 1 | 0.0180402 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0179878 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0177636 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FTL | ferritin, light polypeptide | -0.0826927 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0618129 |
| TMSB10 | thymosin beta 10 | -0.0479936 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0469684 |
| POTEF | POTE ankyrin domain family, member F | -0.0451452 |
| RPL35A | ribosomal protein L35a | -0.0436924 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0344533 |
| PTMA | prothymosin, alpha | -0.0332236 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0331136 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0314057 |
| G0S2 | G0/G1 switch 2 | -0.0307821 |
| PFN1 | profilin 1 | -0.0300891 |
| NDRG1 | N-myc downstream regulated 1 | -0.02858 |
| RPS6 | ribosomal protein S6 | -0.0285399 |
| VIM | vimentin | -0.0263965 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) | -0.0252494 |
| RPLP2 | ribosomal protein, large, P2 | -0.0248412 |
| CSF1 | colony stimulating factor 1 (macrophage) | -0.0232587 |
| HLA-B | major histocompatibility complex, class I, B | -0.0222167 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.021566 |
| RPL37A | ribosomal protein L37a | -0.0208348 |
| CAVIN1 | caveolae associated protein 1 | -0.0205456 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0205082 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0201704 |
| RPS8 | ribosomal protein S8 | -0.0190441 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0179376 |
| HMGB1 | high mobility group box 1 | -0.0176505 |
| RPL28 | ribosomal protein L28 | -0.0174957 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0171811 |
| RPL38 | ribosomal protein L38 | -0.0169042 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0164562 |
| RPL31 | ribosomal protein L31 | -0.0163259 |
| GNAS | GNAS complex locus | -0.0162467 |
| INSIG1 | insulin induced gene 1 | -0.0161602 |
| MTDH | metadherin | -0.0159422 |
| QKI | QKI, KH domain containing, RNA binding | -0.0156069 |
| RPL9 | ribosomal protein L9 | -0.0153323 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0152709 |
| CD70 | CD70 molecule | -0.0151836 |
| RPLP1 | ribosomal protein, large, P1 | -0.015099 |
| RPS21 | ribosomal protein S21 | -0.0149962 |
| CELF1 | CUGBP, Elav-like family member 1 | -0.0149094 |
| RPS13 | ribosomal protein S13 | -0.0142197 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0138195 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | -0.0138 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.013772 |
| RPL19 | ribosomal protein L19 | -0.0136318 |
| ADM | adrenomedullin | -0.0134505 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0132294 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.013172 |
| DENND2B | DENN domain containing 2B | -0.0130039 |
| RPS27A | ribosomal protein S27a | -0.0129922 |
| SERF2 | small EDRK-rich factor 2 | -0.0128848 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.0128838 |
| RPL11 | ribosomal protein L11 | -0.0127256 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | -0.0125507 |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B | -0.0123932 |
| RPS24 | ribosomal protein S24 | -0.0123425 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | -0.0122142 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.012164 |
| HMGA1 | high mobility group AT-hook 1 | -0.0121605 |
| COX4I1 | cytochrome c oxidase subunit IV isoform 1 | -0.011995 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0118923 |
| TCEAL9 | transcription elongation factor A like 9 | -0.0118727 |
| RPL23 | ribosomal protein L23 | -0.0117833 |
| MT2A | metallothionein 2A | -0.0116877 |
| RPL8 | ribosomal protein L8 | -0.0116242 |
| RPS19 | ribosomal protein S19 | -0.011593 |
| PXDN | peroxidasin | -0.0115754 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0115391 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0114757 |
| CSTB | cystatin B (stefin B) | -0.011359 |
| RPS29 | ribosomal protein S29 | -0.0112426 |
| S100A6 | S100 calcium binding protein A6 | -0.0112027 |
| IER3 | immediate early response 3 | -0.0111882 |
| ANKRD10 | ankyrin repeat domain 10 | -0.011081 |
| RPL30 | ribosomal protein L30 | -0.0110235 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.0108109 |
| RPL36A | ribosomal protein L36a | -0.0108077 |
| SEC61G | Sec61 gamma subunit | -0.0108067 |
| RPS5 | ribosomal protein S5 | -0.010806 |
| SEC11A | SEC11 homolog A (S. cerevisiae) | -0.0106327 |
| USP3 | ubiquitin specific peptidase 3 | -0.0106105 |
| PKM | pyruvate kinase, muscle | -0.0105661 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -0.0105494 |
| RHEB | Ras homolog enriched in brain | -0.0104566 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | -0.0103707 |
| EMP3 | epithelial membrane protein 3 | -0.0103527 |
| IL32 | interleukin 32 | -0.0103296 |
| SLC25A3 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 | -0.010282 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0102376 |
| KRT10 | keratin 10, type I | -0.0100981 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.00999442 |
| RPL37 | ribosomal protein L37 | -0.00994241 |
| SSBP1 | single-stranded DNA binding protein 1, mitochondrial | -0.00992029 |
| RPS20 | ribosomal protein S20 | -0.00945239 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | -0.00943773 |
| FN1 | fibronectin 1 | -0.00930298 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.00929454 |
| LMNA | lamin A/C | -0.00924989 |
