| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | ULK-101 perturbation in A549 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the ULK-101_A549 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0646374 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0568792 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0563603 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.052324 |
| PCBP2 | poly(rC) binding protein 2 | 0.0424023 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0409696 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.03814 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0357988 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.031024 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0305772 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0289579 |
| SPAG9 | sperm associated antigen 9 | 0.0288218 |
| FTL | ferritin, light polypeptide | 0.0282493 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0281326 |
| RPL12 | ribosomal protein L12 | 0.0277243 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0275317 |
| FAM107B | family with sequence similarity 107, member B | 0.0271048 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0262814 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0262749 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0261405 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0260824 |
| TKT | transketolase | 0.025285 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.02524 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0243726 |
| RPLP0 | ribosomal protein, large, P0 | 0.0241766 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0236551 |
| ZNF207 | zinc finger protein 207 | 0.023409 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0233369 |
| RACK1 | receptor for activated C kinase 1 | 0.0221912 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0218343 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0214612 |
| WDR43 | WD repeat domain 43 | 0.0214438 |
| RPS17 | ribosomal protein S17 | 0.0211877 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0211576 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0211389 |
| ARB2A | ARB2 cotranscriptional regulator A | 0.0211285 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0210471 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0206459 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0203128 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0203094 |
| AXL | AXL receptor tyrosine kinase | 0.0197227 |
| SMYD3 | SET and MYND domain containing 3 | 0.0195836 |
| RPS12 | ribosomal protein S12 | 0.0191321 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0189511 |
| C15ORF48 | chromosome 15 open reading frame 48 | 0.0188133 |
| CSGALNACT2 | chondroitin sulfate N-acetylgalactosaminyltransferase 2 | 0.0187759 |
| RPS2 | ribosomal protein S2 | 0.0185522 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0183571 |
| PPM1D | protein phosphatase, Mg2+/Mn2+ dependent, 1D | 0.0181334 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0181146 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.01743 |
| RPS4X | ribosomal protein S4, X-linked | 0.0172749 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | 0.017243 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0164402 |
| FMNL2 | formin-like 2 | 0.0164344 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0163746 |
| XPO1 | exportin 1 | 0.0163382 |
| EREG | epiregulin | 0.0161586 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0160695 |
| CA8 | carbonic anhydrase VIII | 0.0160328 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0160299 |
| RPLP1 | ribosomal protein, large, P1 | 0.0159854 |
| TXNRD1 | thioredoxin reductase 1 | 0.0159006 |
| HELZ | helicase with zinc finger | 0.015826 |
| GPATCH2L | G patch domain containing 2-like | 0.0158207 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0158002 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 0.0157866 |
| RPS8 | ribosomal protein S8 | 0.0157452 |
| FOSL1 | FOS-like antigen 1 | 0.0156841 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0156117 |
| ARL5B | ADP-ribosylation factor-like 5B | 0.0155501 |
| NGLY1 | N-glycanase 1 | 0.0153958 |
| RPL7 | ribosomal protein L7 | 0.0153392 |
| RYBP | RING1 and YY1 binding protein | 0.0152739 |
| SFTPA2 | surfactant protein A2 | 0.0152465 |
| EFL1 | elongation factor like GTPase 1 | 0.015241 |
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 | 0.0152399 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0152399 |
| FA2H | fatty acid 2-hydroxylase | 0.0151888 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0150147 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0149613 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0148175 |
| RPS19 | ribosomal protein S19 | 0.0147406 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0146338 |
| GPHN | gephyrin | 0.0144654 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0144255 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0142721 |
| DSTN | destrin (actin depolymerizing factor) | 0.0139568 |
| MSN | moesin | 0.0138698 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0138605 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0136713 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0135584 |
| RIOK3 | RIO kinase 3 | 0.0134581 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0133634 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0133403 |
| NBAS | neuroblastoma amplified sequence | 0.0132729 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.013245 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.013219 |
| TPM3 | tropomyosin 3 | 0.0131751 |
| RPL18 | ribosomal protein L18 | 0.013079 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.136221 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.130724 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.118777 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.103995 |
| TMSB10 | thymosin beta 10 | -0.0941559 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0913061 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0772377 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0720286 |
| NDRG1 | N-myc downstream regulated 1 | -0.0681335 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | -0.0621785 |
| DOCK5 | dedicator of cytokinesis 5 | -0.061897 |
| ACTG1 | actin gamma 1 | -0.0592395 |
| PDE10A | phosphodiesterase 10A | -0.0565294 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0538279 |
| KRT81 | keratin 81, type II | -0.0527956 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0527264 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0508394 |
| VCL | vinculin | -0.0504804 |
| EHBP1 | EH domain binding protein 1 | -0.049374 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0488333 |
| OSMR | oncostatin M receptor | -0.0457173 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0437824 |
| ANXA2 | annexin A2 | -0.0415107 |
| AUTS2 | autism susceptibility candidate 2 | -0.0397527 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.037725 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0374351 |
| EFNA5 | ephrin-A5 | -0.0362322 |
| MT2A | metallothionein 2A | -0.0362261 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0352488 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0348458 |
| BICC1 | BicC family RNA binding protein 1 | -0.0345849 |
| ZFHX3 | zinc finger homeobox 3 | -0.0344237 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0342387 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0335764 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -0.0333949 |
| PRKCA | protein kinase C, alpha | -0.0331286 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0323486 |
| MT1X | metallothionein 1X | -0.0322568 |
| RIN2 | Ras and Rab interactor 2 | -0.0322206 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0315528 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.031494 |
| TPM1 | tropomyosin 1 (alpha) | -0.0308548 |
| ASPH | aspartate beta-hydroxylase | -0.0306769 |
| CMIP | c-Maf inducing protein | -0.0301052 |
| ACTN4 | actinin, alpha 4 | -0.0298827 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0295118 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0294092 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0290318 |
| TNS3 | tensin 3 | -0.0287019 |
| SLC35F3 | solute carrier family 35, member F3 | -0.028577 |
| MAP1B | microtubule-associated protein 1B | -0.0282168 |
| NRG1 | neuregulin 1 | -0.0277697 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0277496 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.027429 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.027022 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0262916 |
| ANXA4 | annexin A4 | -0.026277 |
| NTN4 | netrin 4 | -0.0261286 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.025797 |
| ABTB3 | ankyrin repeat and BTB domain containing 3 | -0.025713 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0254135 |
| PARD3 | par-3 family cell polarity regulator | -0.025399 |
| PTMA | prothymosin, alpha | -0.0252053 |
| RNF213 | ring finger protein 213 | -0.0251829 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0243514 |
| TPM4 | tropomyosin 4 | -0.0242973 |
| RPL35A | ribosomal protein L35a | -0.0238822 |
| RPS27A | ribosomal protein S27a | -0.0238372 |
| H1-0 | H1.0 linker histone | -0.0237948 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0236928 |
| RPL37A | ribosomal protein L37a | -0.0232447 |
| POTEF | POTE ankyrin domain family, member F | -0.0229697 |
| S100A6 | S100 calcium binding protein A6 | -0.0227402 |
| EGFR | epidermal growth factor receptor | -0.0222101 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0222005 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0218602 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0218343 |
| CUX1 | cut-like homeobox 1 | -0.0218217 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.0218121 |
| MKI67 | marker of proliferation Ki-67 | -0.0217243 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.021647 |
| HLA-B | major histocompatibility complex, class I, B | -0.021336 |
| MYO1E | myosin IE | -0.0212182 |
| ERGIC1 | endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 | -0.0210238 |
| CAVIN1 | caveolae associated protein 1 | -0.0209993 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0205471 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | -0.0205252 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.020268 |
| RAI14 | retinoic acid induced 14 | -0.0200968 |
| PDE8A | phosphodiesterase 8A | -0.0200921 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0199464 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0196887 |
| CP | ceruloplasmin (ferroxidase) | -0.0193925 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0192647 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.019161 |
| HMGA2 | high mobility group AT-hook 2 | -0.0190989 |
| COL4A5 | collagen, type IV, alpha 5 | -0.0185914 |
| BMERB1 | bMERB domain containing 1 | -0.0185542 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0185047 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0183229 |
