| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | ULK-101 perturbation in AsPC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the ULK-101_AsPC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.148337 |
| VIM | vimentin | 0.138387 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.112242 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0969186 |
| TXNRD1 | thioredoxin reductase 1 | 0.0936595 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0708008 |
| EGFR | epidermal growth factor receptor | 0.0701118 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0697956 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | 0.0657862 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0615034 |
| RIOK3 | RIO kinase 3 | 0.0601548 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0562272 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0560276 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.0550413 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0515282 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0468081 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0450619 |
| ACTG1 | actin gamma 1 | 0.0442859 |
| S100A10 | S100 calcium binding protein A10 | 0.0434319 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.0430197 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | 0.042425 |
| S100A6 | S100 calcium binding protein A6 | 0.0419618 |
| EFNA5 | ephrin-A5 | 0.041588 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0398716 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0396982 |
| PTMA | prothymosin, alpha | 0.0392495 |
| ERBIN | erbb2 interacting protein | 0.0389474 |
| MMP1 | matrix metallopeptidase 1 | 0.0385034 |
| SPAG9 | sperm associated antigen 9 | 0.038332 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0382575 |
| LMTK2 | lemur tyrosine kinase 2 | 0.0380282 |
| FMNL2 | formin-like 2 | 0.0379981 |
| ARPC1A | actin related protein 2/3 complex, subunit 1A, 41kDa | 0.0372956 |
| MED13L | mediator complex subunit 13-like | 0.0372775 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0371537 |
| RCOR1 | REST corepressor 1 | 0.0369629 |
| UBC | ubiquitin C | 0.0369612 |
| JMJD1C | jumonji domain containing 1C | 0.036884 |
| ATP13A3 | ATPase type 13A3 | 0.034593 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0343059 |
| RAB10 | RAB10, member RAS oncogene family | 0.0330417 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0328672 |
| RPLP1 | ribosomal protein, large, P1 | 0.0325517 |
| VMP1 | vacuole membrane protein 1 | 0.0319501 |
| RPLP0 | ribosomal protein, large, P0 | 0.0314898 |
| PCBP2 | poly(rC) binding protein 2 | 0.0311482 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0309858 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.030726 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0305771 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0305753 |
| TMSB10 | thymosin beta 10 | 0.030281 |
| SNX9 | sorting nexin 9 | 0.0302675 |
| SGMS2 | sphingomyelin synthase 2 | 0.0302213 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0300747 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0298258 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0297835 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0296678 |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit | 0.0295234 |
| SQSTM1 | sequestosome 1 | 0.0293965 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0293917 |
| ASPH | aspartate beta-hydroxylase | 0.0293892 |
| POTEF | POTE ankyrin domain family, member F | 0.0293843 |
| PARD3 | par-3 family cell polarity regulator | 0.0291125 |
| BMP6 | bone morphogenetic protein 6 | 0.0290892 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0290588 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0283751 |
| UBE2R2 | ubiquitin-conjugating enzyme E2R 2 | 0.027977 |
| RPS8 | ribosomal protein S8 | 0.0276672 |
| RACK1 | receptor for activated C kinase 1 | 0.027416 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0273329 |
| FGD6 | FYVE, RhoGEF and PH domain containing 6 | 0.0271901 |
| TPM3 | tropomyosin 3 | 0.0270972 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0269632 |
| SIK3 | SIK family kinase 3 | 0.0268332 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | 0.0267436 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0263326 |
| RPL7 | ribosomal protein L7 | 0.0263066 |
| SEPTIN7 | septin 7 | 0.0260043 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0259485 |
| SDC4 | syndecan 4 | 0.0259208 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0256303 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.025502 |
| EZR | ezrin | 0.025493 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0254641 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0253823 |
| KIF5B | kinesin family member 5B | 0.0243027 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0241234 |
| DIAPH1 | diaphanous-related formin 1 | 0.0239505 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0238854 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0238346 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.023771 |
| IPO7 | importin 7 | 0.0236808 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0232334 |
| MATR3 | matrin 3 | 0.0232277 |
| NDRG1 | N-myc downstream regulated 1 | 0.0231933 |
| MCL1 | myeloid cell leukemia 1 | 0.0231534 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0231402 |
| SMAD3 | SMAD family member 3 | 0.0230558 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0230093 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0228988 |
| Symbol | Name | Standardized Value |
|---|---|---|
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.112681 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 | -0.0976981 |
| LAMB3 | laminin, beta 3 | -0.0893277 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0814747 |
| NPSR1 | neuropeptide S receptor 1 | -0.0803617 |
| LMO7 | LIM domain 7 | -0.0773146 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0597816 |
| MUC17 | mucin 17, cell surface associated | -0.0562787 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0494857 |
| SKAP2 | src kinase associated phosphoprotein 2 | -0.0481831 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0475897 |
| PRELID2 | PRELI domain containing 2 | -0.0474289 |
| MXD1 | MAX dimerization protein 1 | -0.0409353 |
| KLK10 | kallikrein-related peptidase 10 | -0.0409142 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0403568 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0396357 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0385013 |
| VCAN | versican | -0.0369926 |
| RRBP1 | ribosome binding protein 1 | -0.0342157 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0341264 |
| RNF213 | ring finger protein 213 | -0.0337467 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B | -0.0321081 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | -0.0320053 |
| ATG16L1 | autophagy related 16-like 1 (S. cerevisiae) | -0.031722 |
| FLNB | filamin B, beta | -0.031112 |
| TXNIP | thioredoxin interacting protein | -0.0310279 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0301508 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0294906 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0294401 |
| INPP5D | inositol polyphosphate-5-phosphatase, 145kDa | -0.0292126 |
| LAMA4 | laminin, alpha 4 | -0.0283576 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0281274 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | -0.0276915 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0276694 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.026926 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0268816 |
| RIGI | RNA sensor RIG-I | -0.0266533 |
| TGFA | transforming growth factor, alpha | -0.0256852 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.0251341 |
| TRRAP | transformation/transcription domain-associated protein | -0.0242563 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | -0.0236076 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0235578 |
| SP100 | SP100 nuclear antigen | -0.0232896 |
| PMM2 | phosphomannomutase 2 | -0.0230165 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0227193 |
| TMEM263 | transmembrane protein 263 | -0.0224086 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | -0.0220113 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.021956 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0216512 |
| HDAC9 | histone deacetylase 9 | -0.0215584 |
| SLC22A3 | solute carrier family 22 (organic cation transporter), member 3 | -0.0214919 |
| PTPRB | protein tyrosine phosphatase, receptor type, B | -0.0212839 |
| PLSCR1 | phospholipid scramblase 1 | -0.0212022 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0209757 |
| SACK1A | scaffolding CK1 anchoring protein A | -0.0206126 |
| EXOC4 | exocyst complex component 4 | -0.0203382 |
| NBEAL1 | neurobeachin-like 1 | -0.0203196 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | -0.0202495 |
| SERINC5 | serine incorporator 5 | -0.0201607 |
| PLEC | plectin | -0.0200799 |
| DENND1A | DENN/MADD domain containing 1A | -0.0197689 |
| MX1 | MX dynamin-like GTPase 1 | -0.0196269 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0195794 |
| SVIL | supervillin | -0.0195567 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0195467 |
| RNASET2 | ribonuclease T2 | -0.0194347 |
| NABP1 | nucleic acid binding protein 1 | -0.0192545 |
| ARF4 | ADP-ribosylation factor 4 | -0.0190288 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0189255 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0188676 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0188652 |
| HELZ2 | helicase with zinc finger 2, transcriptional coactivator | -0.018638 |
| SCFD2 | sec1 family domain containing 2 | -0.0185621 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0185293 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0182406 |
| SAV1 | salvador family WW domain containing protein 1 | -0.0181974 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.0179696 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0179682 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0178515 |
| EGR1 | early growth response 1 | -0.0176317 |
| FERMT1 | fermitin family member 1 | -0.0175657 |
| GNAS | GNAS complex locus | -0.0175424 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0175297 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | -0.0174669 |
| LAMA5 | laminin, alpha 5 | -0.0172274 |
| TPM4 | tropomyosin 4 | -0.0171302 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0170448 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | -0.0169048 |
| RAD51B | RAD51 paralog B | -0.0166482 |
| ACTN4 | actinin, alpha 4 | -0.0165642 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.0165525 |
| MX2 | MX dynamin-like GTPase 2 | -0.016532 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0164455 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0164094 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0163888 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0163681 |
| ADAR | adenosine deaminase, RNA-specific | -0.0160996 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | -0.015678 |
| SLC9A3R2 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 | -0.0156432 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0156164 |
