| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | ULK-101 perturbation in C-33 A cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the ULK-101_C-33 A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NEBL | nebulette | 0.163251 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.11172 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0896319 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | 0.0832453 |
| ZNF608 | zinc finger protein 608 | 0.0824701 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.080868 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0761404 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0742889 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.068727 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0670004 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.064373 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0629618 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0624203 |
| ENO1 | enolase 1, (alpha) | 0.0621868 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0591625 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0574308 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0569514 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0555373 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0539394 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0517556 |
| RCC1 | regulator of chromosome condensation 1 | 0.0494315 |
| SNX14 | sorting nexin 14 | 0.049406 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0489521 |
| UBAP2 | ubiquitin associated protein 2 | 0.0473944 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0473772 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0470302 |
| WLS | wntless Wnt ligand secretion mediator | 0.0469255 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | 0.0466988 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0453991 |
| DENND1A | DENN/MADD domain containing 1A | 0.0446745 |
| VMP1 | vacuole membrane protein 1 | 0.0436772 |
| ZNF638 | zinc finger protein 638 | 0.04265 |
| AEBP2 | AE binding protein 2 | 0.0421258 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0415217 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0410395 |
| USP34 | ubiquitin specific peptidase 34 | 0.0402631 |
| NBEAL1 | neurobeachin-like 1 | 0.0395021 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0387754 |
| JMJD1C | jumonji domain containing 1C | 0.03823 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.038176 |
| ASPH | aspartate beta-hydroxylase | 0.0380566 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0378217 |
| CUX1 | cut-like homeobox 1 | 0.037737 |
| INTS6 | integrator complex subunit 6 | 0.0376215 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0373643 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0368835 |
| STAG2 | stromal antigen 2 | 0.0353673 |
| SET | SET nuclear proto-oncogene | 0.0351062 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0348779 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0347249 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0346668 |
| FAM193A | family with sequence similarity 193, member A | 0.0342121 |
| LARP1B | La ribonucleoprotein domain family, member 1B | 0.0340163 |
| AGO3 | argonaute RISC catalytic component 3 | 0.0335775 |
| VCL | vinculin | 0.0331946 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0331075 |
| PSPC1 | paraspeckle component 1 | 0.0328509 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0325702 |
| RPS12 | ribosomal protein S12 | 0.032511 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0324062 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.032241 |
| PCM1 | pericentriolar material 1 | 0.0319735 |
| PCBP2 | poly(rC) binding protein 2 | 0.0319438 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0318492 |
| SIK2 | salt-inducible kinase 2 | 0.03175 |
| KAT6B | K(lysine) acetyltransferase 6B | 0.0317017 |
| TTC17 | tetratricopeptide repeat domain 17 | 0.0316513 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.031611 |
| DMXL1 | Dmx-like 1 | 0.0314508 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0308417 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0306232 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | 0.0293382 |
| SCFD1 | sec1 family domain containing 1 | 0.0290445 |
| MSH4 | mutS homolog 4 | 0.0289617 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | 0.0289348 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0288684 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0288012 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0286603 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0283839 |
| SPAG9 | sperm associated antigen 9 | 0.0283764 |
| RPLP0 | ribosomal protein, large, P0 | 0.0283109 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0279826 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0278395 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0277496 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | 0.0273873 |
| RPS4X | ribosomal protein S4, X-linked | 0.027238 |
| EPC2 | enhancer of polycomb homolog 2 (Drosophila) | 0.027226 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0271016 |
| ATM | ATM serine/threonine kinase | 0.0269972 |
| JUN | jun proto-oncogene | 0.0269431 |
| PRKAR1B | protein kinase, cAMP-dependent, regulatory, type I, beta | 0.0267042 |
| PDE7A | phosphodiesterase 7A | 0.0264114 |
| AFG2A | AFG2 AAA ATPase homolog A | 0.0262563 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0260927 |
| GOLGB1 | golgin B1 | 0.0260022 |
| ANKRD17 | ankyrin repeat domain 17 | 0.025936 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | 0.0259117 |
| ZNF609 | zinc finger protein 609 | 0.0254727 |
| SIK3 | SIK family kinase 3 | 0.0254014 |
| UBE3C | ubiquitin protein ligase E3C | 0.0252501 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RAD51B | RAD51 paralog B | -0.185935 |
| SEMA3D | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D | -0.142808 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.097005 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0962562 |
| SHROOM3 | shroom family member 3 | -0.0924782 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0826029 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0749162 |
| NR5A2 | nuclear receptor subfamily 5, group A, member 2 | -0.0733006 |
| TMSB10 | thymosin beta 10 | -0.0667031 |
| NPAS3 | neuronal PAS domain protein 3 | -0.0627982 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0613075 |
| EGR1 | early growth response 1 | -0.0580697 |
| CADM2 | cell adhesion molecule 2 | -0.0556298 |
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 | -0.0526048 |
| GRID2 | glutamate receptor, ionotropic, delta 2 | -0.0516317 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0503585 |
| RIGI | RNA sensor RIG-I | -0.0489287 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | -0.0488366 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0487785 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0487025 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0484099 |
| H1-0 | H1.0 linker histone | -0.0471707 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0465096 |
| SLF1 | SMC5-SMC6 complex localization factor 1 | -0.0440338 |
| WDR45B | WD repeat domain 45B | -0.0438506 |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 | -0.042869 |
| TMEM41B | transmembrane protein 41B | -0.041744 |
| SOX2 | SRY (sex determining region Y)-box 2 | -0.040292 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0400933 |
| RTN4 | reticulon 4 | -0.0377595 |
| FAM162A | family with sequence similarity 162, member A | -0.0369258 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0349458 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0346443 |
| MAP1B | microtubule-associated protein 1B | -0.0345839 |
| TPI1 | triosephosphate isomerase 1 | -0.0339029 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0334329 |
| HMGB1 | high mobility group box 1 | -0.0326512 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0323018 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0320056 |
| GNAS | GNAS complex locus | -0.0317436 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0317155 |
| MIMS1 | mitochondrial inner membrane scaffold 1 | -0.0314882 |
| PTMA | prothymosin, alpha | -0.0311203 |
| MAGEA4 | melanoma antigen family A4 | -0.0305451 |
| GJA1 | gap junction protein, alpha 1, 43kDa | -0.0301371 |
| ZFP64 | ZFP64 zinc finger protein | -0.0295414 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0292731 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0280864 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0279915 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0279442 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0278254 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0278103 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0277656 |
| CBX3 | chromobox homolog 3 | -0.0276395 |
| ADAM17 | ADAM metallopeptidase domain 17 | -0.0275714 |
| PGAP1 | post-GPI attachment to proteins 1 | -0.0274481 |
| ADAR | adenosine deaminase, RNA-specific | -0.0274366 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0273095 |
| RPL35A | ribosomal protein L35a | -0.0270255 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | -0.0262038 |
| KIAA1958 | KIAA1958 | -0.0261617 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0261029 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0252564 |
| MIPOL1 | mirror-image polydactyly 1 | -0.0248496 |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha | -0.0246407 |
| NOP58 | NOP58 ribonucleoprotein | -0.0243004 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0242689 |
| RLF | rearranged L-myc fusion | -0.0240989 |
| RPL11 | ribosomal protein L11 | -0.0240804 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0240027 |
| H3-3B | H3.3 histone B | -0.0238394 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0237629 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | -0.0237179 |
| RRBP1 | ribosome binding protein 1 | -0.023668 |
| YBX1 | Y box binding protein 1 | -0.0236219 |
| CAVIN1 | caveolae associated protein 1 | -0.0235193 |
| RPS21 | ribosomal protein S21 | -0.0234757 |
| TUBB | tubulin, beta class I | -0.0233231 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | -0.0229981 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.0229607 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0226855 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.0226275 |
| CEP95 | centrosomal protein 95kDa | -0.0224432 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | -0.0223941 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0219928 |
| RHEB | Ras homolog enriched in brain | -0.0218648 |
| NOC3L | nucleolar complex associated 3 homolog (S. cerevisiae) | -0.0216778 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0216554 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0215583 |
| RPL38 | ribosomal protein L38 | -0.0214285 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0213852 |
| RAN | RAN, member RAS oncogene family | -0.0213187 |
| FTL | ferritin, light polypeptide | -0.0212843 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.0212606 |
| SEPTIN10 | septin 10 | -0.0212099 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -0.0209792 |
| ATRN | attractin | -0.0209505 |
| TJP1 | tight junction protein 1 | -0.0209188 |
| HELZ2 | helicase with zinc finger 2, transcriptional coactivator | -0.0206275 |
| CELF2 | CUGBP, Elav-like family member 2 | -0.0205349 |
