| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | ULK-101 perturbation in C32 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the ULK-101_C32 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.139432 |
| GPC6 | glypican 6 | 0.139422 |
| FN1 | fibronectin 1 | 0.137034 |
| FMN1 | formin 1 | 0.13319 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0857462 |
| VIM | vimentin | 0.0838611 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | 0.0791675 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.0627712 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0617851 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0607567 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0549309 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.054876 |
| CUX1 | cut-like homeobox 1 | 0.0501668 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0492213 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0487968 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.048467 |
| VCL | vinculin | 0.0479594 |
| COL19A1 | collagen, type XIX, alpha 1 | 0.0475901 |
| DST | dystonin | 0.0461149 |
| CALU | calumenin | 0.045938 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0456819 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0442361 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0434181 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.043183 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0430003 |
| ASPH | aspartate beta-hydroxylase | 0.0426963 |
| IFRD1 | interferon-related developmental regulator 1 | 0.0425441 |
| APP | amyloid beta (A4) precursor protein | 0.0381801 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0380423 |
| TLE4 | transducin-like enhancer of split 4 | 0.0377075 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0376797 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0375922 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.037482 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0365893 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0363476 |
| PTCHD4 | patched domain containing 4 | 0.035712 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0352833 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0352085 |
| ACTG1 | actin gamma 1 | 0.0348643 |
| MYO1E | myosin IE | 0.0345532 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0343374 |
| NLGN1 | neuroligin 1 | 0.0338568 |
| VMP1 | vacuole membrane protein 1 | 0.0337334 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0334911 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.032498 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0321721 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | 0.0320189 |
| SFTPA2 | surfactant protein A2 | 0.0314737 |
| ACTN1 | actinin, alpha 1 | 0.031393 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0311549 |
| SETBP1 | SET binding protein 1 | 0.0308899 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 | 0.0308832 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0306241 |
| FRMD4A | FERM domain containing 4A | 0.0304898 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0303883 |
| EXOC4 | exocyst complex component 4 | 0.0298822 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0293994 |
| UBE3C | ubiquitin protein ligase E3C | 0.029218 |
| CADM1 | cell adhesion molecule 1 | 0.0290287 |
| NAV1 | neuron navigator 1 | 0.0279782 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | 0.0277803 |
| PRELID2 | PRELI domain containing 2 | 0.0275834 |
| SMYD3 | SET and MYND domain containing 3 | 0.0274233 |
| USP34 | ubiquitin specific peptidase 34 | 0.0273311 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.026897 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0264839 |
| ITGB8 | integrin, beta 8 | 0.025992 |
| GDF15 | growth differentiation factor 15 | 0.0259798 |
| EHBP1 | EH domain binding protein 1 | 0.0256625 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0255941 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0254903 |
| PAX3 | paired box 3 | 0.0254449 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0253794 |
| EFCAB13 | EF-hand calcium binding domain 13 | 0.0253695 |
| SQSTM1 | sequestosome 1 | 0.0253659 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0249396 |
| GPHN | gephyrin | 0.024613 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.0244039 |
| ATXN1 | ataxin 1 | 0.0243354 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.024307 |
| PTK2 | protein tyrosine kinase 2 | 0.0242487 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0242423 |
| SDC2 | syndecan 2 | 0.0242216 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.024214 |
| ADAM19 | ADAM metallopeptidase domain 19 | 0.024008 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0239415 |
| HBP1 | HMG-box transcription factor 1 | 0.0237974 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0237765 |
| ENO1 | enolase 1, (alpha) | 0.0237021 |
| COG5 | component of oligomeric golgi complex 5 | 0.0235308 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0232949 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0232874 |
| LRRC23 | leucine rich repeat containing 23 | 0.0231316 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0230928 |
| SPAG9 | sperm associated antigen 9 | 0.0229021 |
| HMGA2 | high mobility group AT-hook 2 | 0.0228252 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0226994 |
| MCL1 | myeloid cell leukemia 1 | 0.0225555 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0224417 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0224288 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | -0.0859445 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0705863 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0536809 |
| MT2A | metallothionein 2A | -0.0531619 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0491761 |
| TMSB10 | thymosin beta 10 | -0.0471073 |
| RNF145 | ring finger protein 145 | -0.0431158 |
| NUP58 | nucleoporin 58 | -0.041787 |
| TAGLN2 | transgelin 2 | -0.037913 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.0368888 |
| INSIG1 | insulin induced gene 1 | -0.0353569 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0350509 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0340879 |
| CENPF | centromere protein F, 350/400kDa | -0.0340524 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0328 |
| RFX7 | regulatory factor X, 7 | -0.0323425 |
| FOSL1 | FOS-like antigen 1 | -0.0296449 |
| WDR45B | WD repeat domain 45B | -0.0290675 |
| LEF1 | lymphoid enhancer-binding factor 1 | -0.0285269 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0281722 |
| RNF24 | ring finger protein 24 | -0.0278461 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0275124 |
| TNFRSF19 | tumor necrosis factor receptor superfamily, member 19 | -0.0272604 |
| MT1X | metallothionein 1X | -0.0265073 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0254254 |
| CABIN1 | calcineurin binding protein 1 | -0.0253941 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.0250357 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0249473 |
| POTEF | POTE ankyrin domain family, member F | -0.0249239 |
| GNAS | GNAS complex locus | -0.0247218 |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain | -0.0244377 |
| S100A6 | S100 calcium binding protein A6 | -0.0242302 |
| PFN1 | profilin 1 | -0.0229918 |
| SETD5 | SET domain containing 5 | -0.0226409 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0225425 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0218501 |
| PKM | pyruvate kinase, muscle | -0.0216826 |
| VGF | VGF nerve growth factor inducible | -0.0209569 |
| FOXJ3 | forkhead box J3 | -0.0209168 |
| TFG | TRK-fused gene | -0.0208869 |
| LDHA | lactate dehydrogenase A | -0.0207851 |
| DCT | dopachrome tautomerase | -0.0207554 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0202832 |
| ADM | adrenomedullin | -0.0197275 |
| TNPO3 | transportin 3 | -0.0197033 |
| PTMA | prothymosin, alpha | -0.0196152 |
| RNF150 | ring finger protein 150 | -0.0195785 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0195118 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | -0.0192139 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0191667 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0187239 |
| YBX1 | Y box binding protein 1 | -0.018667 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0186087 |
| TBK1 | TANK-binding kinase 1 | -0.0185286 |
| FTL | ferritin, light polypeptide | -0.0183192 |
| CCNL1 | cyclin L1 | -0.0183025 |
| XPO1 | exportin 1 | -0.0182006 |
| HLA-B | major histocompatibility complex, class I, B | -0.0176723 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0175658 |
| DIAPH3 | diaphanous-related formin 3 | -0.0173661 |
| TPI1 | triosephosphate isomerase 1 | -0.0171103 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0170757 |
| TRA2B | transformer 2 beta homolog (Drosophila) | -0.016987 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0169867 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0168006 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0167513 |
| IFITM2 | interferon induced transmembrane protein 2 | -0.0167298 |
| TAC4 | tachykinin 4 (hemokinin) | -0.0166729 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0166522 |
| RPS6 | ribosomal protein S6 | -0.0165317 |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) | -0.0163328 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | -0.0162776 |
| CHSY1 | chondroitin sulfate synthase 1 | -0.0160763 |
| RPS19 | ribosomal protein S19 | -0.015912 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | -0.0158771 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0158419 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | -0.0155939 |
| SCAF4 | SR-related CTD-associated factor 4 | -0.0155119 |
| MACROD2 | MACRO domain containing 2 | -0.0153744 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0153038 |
| CALD1 | caldesmon 1 | -0.0152866 |
| CSNK1E | casein kinase 1, epsilon | -0.0152721 |
| ARRDC3 | arrestin domain containing 3 | -0.0152684 |
| COPA | coatomer protein complex, subunit alpha | -0.015237 |
| COL1A2 | collagen, type I, alpha 2 | -0.0150472 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0148991 |
| FIP1L1 | factor interacting with PAPOLA and CPSF1 | -0.0148584 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0147838 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0147398 |
| BARD1 | BRCA1 associated RING domain 1 | -0.0146009 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | -0.0145923 |
| S100A10 | S100 calcium binding protein A10 | -0.0145167 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0144408 |
| RPLP2 | ribosomal protein, large, P2 | -0.0142939 |
| CD9 | CD9 molecule | -0.0134648 |
| CLEC1B | C-type lectin domain family 1, member B | -0.0134247 |
| VGLL4 | vestigial-like family member 4 | -0.0132385 |
| B2M | beta-2-microglobulin | -0.0132336 |
| MMS19 | MMS19 nucleotide excision repair homolog (S. cerevisiae) | -0.0132329 |
| SGO2 | shugoshin 2 | -0.0131662 |
