| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | ULK-101 perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the ULK-101_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | 0.135302 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0900858 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0612825 |
| SMAD3 | SMAD family member 3 | 0.0545776 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0467549 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0451991 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0399094 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0373538 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0366534 |
| CANX | calnexin | 0.0365646 |
| VMP1 | vacuole membrane protein 1 | 0.036213 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0359296 |
| COG6 | component of oligomeric golgi complex 6 | 0.0342813 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0313546 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0309057 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0307243 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0283992 |
| HM13 | histocompatibility (minor) 13 | 0.0278156 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0274045 |
| TMEM65 | transmembrane protein 65 | 0.0269263 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0268581 |
| GOLGB1 | golgin B1 | 0.0258482 |
| COPA | coatomer protein complex, subunit alpha | 0.0257321 |
| SEC24D | SEC24 family member D | 0.0252532 |
| SEC24A | SEC24 family member A | 0.0250168 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.0249507 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0245948 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.024452 |
| CALR | calreticulin | 0.0241323 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0238161 |
| AHI1 | Abelson helper integration site 1 | 0.0236805 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0229023 |
| SPAG9 | sperm associated antigen 9 | 0.0227245 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0221457 |
| GOLGA4 | golgin A4 | 0.0220866 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0217913 |
| HDLBP | high density lipoprotein binding protein | 0.0217418 |
| MORF4L2 | mortality factor 4 like 2 | 0.0217073 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0216114 |
| SUCO | SUN domain containing ossification factor | 0.0212073 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | 0.0211861 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0210212 |
| CALU | calumenin | 0.0202918 |
| TOP1 | topoisomerase (DNA) I | 0.0202757 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0200418 |
| UBL3 | ubiquitin-like 3 | 0.0195867 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | 0.0195631 |
| DIS3 | DIS3 exosome endoribonuclease and 3'-5' exoribonuclease | 0.0192649 |
| SIPA1L2 | signal-induced proliferation-associated 1 like 2 | 0.0191132 |
| IRF1 | interferon regulatory factor 1 | 0.0187034 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0186714 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0186656 |
| SEPTIN9 | septin 9 | 0.0181167 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.018021 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0179715 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0179376 |
| RFFL | ring finger and FYVE-like domain containing E3 ubiquitin protein ligase | 0.0179227 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0177034 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0176977 |
| PGM3 | phosphoglucomutase 3 | 0.0175996 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0175637 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0174586 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0171018 |
| SRP54 | signal recognition particle 54kDa | 0.0171013 |
| CDHR2 | cadherin-related family member 2 | 0.0169286 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0167966 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0166782 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | 0.0166533 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0161932 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0160512 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.0160155 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0160079 |
| DST | dystonin | 0.0159768 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0159449 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | 0.0159062 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0158245 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0156881 |
| MYO1E | myosin IE | 0.0156596 |
| ZBTB43 | zinc finger and BTB domain containing 43 | 0.0156555 |
| ERLEC1 | endoplasmic reticulum lectin 1 | 0.015633 |
| UFM1 | ubiquitin-fold modifier 1 | 0.0153288 |
| HYOU1 | hypoxia up-regulated 1 | 0.015237 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0152162 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0151501 |
| EFNB2 | ephrin-B2 | 0.0151328 |
| SSR1 | signal sequence receptor, alpha | 0.015107 |
| USP53 | ubiquitin specific peptidase 53 | 0.0148294 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0146683 |
| AGR2 | anterior gradient 2 | 0.0146286 |
| FNIP1 | folliculin interacting protein 1 | 0.0145424 |
| KYNU | kynureninase | 0.0145422 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0145269 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | 0.0144935 |
| ARF4 | ADP-ribosylation factor 4 | 0.0144811 |
| PCBP2 | poly(rC) binding protein 2 | 0.0142958 |
| KLHL24 | kelch-like family member 24 | 0.0142679 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0142544 |
| SEC22A | SEC22 vesicle trafficking protein homolog A (S. cerevisiae) | 0.0141743 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0141486 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0140525 |
| Symbol | Name | Standardized Value |
|---|---|---|
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.162002 |
| RNF213 | ring finger protein 213 | -0.128568 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.114266 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0951508 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0924871 |
| XAF1 | XIAP associated factor 1 | -0.0893877 |
| RIGI | RNA sensor RIG-I | -0.0841625 |
| MX1 | MX dynamin-like GTPase 1 | -0.0820869 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.079099 |
| SP100 | SP100 nuclear antigen | -0.07888 |
| STS | steroid sulfatase (microsomal), isozyme S | -0.0729708 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0708939 |
| MX2 | MX dynamin-like GTPase 2 | -0.069926 |
| NPSR1 | neuropeptide S receptor 1 | -0.069408 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0686651 |
| LYZ | lysozyme | -0.0659206 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0644487 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0636953 |
| PTMA | prothymosin, alpha | -0.0628165 |
| VCL | vinculin | -0.0625067 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0587341 |
| HLA-B | major histocompatibility complex, class I, B | -0.0532828 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.052889 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0511258 |
| PRKCA | protein kinase C, alpha | -0.050973 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0481287 |
| PMP22 | peripheral myelin protein 22 | -0.047701 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0465157 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0450034 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0446618 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.0422203 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.0421814 |
| MUC20 | mucin 20, cell surface associated | -0.0417372 |
| SSH2 | slingshot protein phosphatase 2 | -0.0394191 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.039333 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0378352 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.036149 |
| H1-0 | H1.0 linker histone | -0.035022 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0349433 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0347943 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa | -0.0344554 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0336678 |
| NCKAP5 | NCK-associated protein 5 | -0.0334327 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | -0.0322857 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | -0.0321258 |
| APOL1 | apolipoprotein L, 1 | -0.0320023 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0313452 |
| PLSCR1 | phospholipid scramblase 1 | -0.0313092 |
| MECOM | MDS1 and EVI1 complex locus | -0.0307707 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | -0.030318 |
| RAD51B | RAD51 paralog B | -0.0300478 |
| ETV6 | ets variant 6 | -0.0298982 |
| ERBIN | erbb2 interacting protein | -0.0298659 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0297877 |
| ACTG1 | actin gamma 1 | -0.029782 |
| CSTPP1 | centriolar satellite-associated tubulin polyglutamylase complex regulator 1 | -0.0297591 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 | -0.0296679 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0294496 |
| DGKH | diacylglycerol kinase, eta | -0.0292614 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0283365 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.028091 |
| RPL7L1 | ribosomal protein L7-like 1 | -0.0276889 |
| TBC1D22A | TBC1 domain family, member 22A | -0.027273 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0271883 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0267822 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0266873 |
| MUC13 | mucin 13, cell surface associated | -0.0263441 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0262916 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0262663 |
| ATP10B | ATPase, class V, type 10B | -0.0261946 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0257731 |
| SAMD9L | sterile alpha motif domain containing 9-like | -0.0257627 |
| PTGR1 | prostaglandin reductase 1 | -0.0256363 |
| LIMA1 | LIM domain and actin binding 1 | -0.0251734 |
| TRIM56 | tripartite motif containing 56 | -0.0249846 |
| APOL6 | apolipoprotein L, 6 | -0.0249271 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0248442 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.024724 |
| RPL35A | ribosomal protein L35a | -0.0244102 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | -0.0244041 |
| PTK2 | protein tyrosine kinase 2 | -0.02421 |
| JUN | jun proto-oncogene | -0.0236736 |
| DOCK1 | dedicator of cytokinesis 1 | -0.0235128 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0232722 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.023038 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0229496 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0227884 |
| HLA-C | major histocompatibility complex, class I, C | -0.0227716 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.022678 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.0226347 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0225424 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0223737 |
| LLGL2 | lethal giant larvae homolog 2 (Drosophila) | -0.0223412 |
| MICU2 | mitochondrial calcium uptake 2 | -0.0222923 |
| LAP3 | leucine aminopeptidase 3 | -0.0222137 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0221612 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0220384 |
| SORBS1 | sorbin and SH3 domain containing 1 | -0.0219985 |
| PARP9 | poly (ADP-ribose) polymerase family, member 9 | -0.0217819 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.021418 |
