| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | ULK-101 perturbation in H4 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the ULK-101_H4 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0933981 |
| STC1 | stanniocalcin 1 | 0.0894154 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0808234 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0612852 |
| FNDC3B | fibronectin type III domain containing 3B | 0.055578 |
| NDRG1 | N-myc downstream regulated 1 | 0.0545683 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0541819 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.052527 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0471406 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0439703 |
| HMGA2 | high mobility group AT-hook 2 | 0.0367761 |
| EGFR | epidermal growth factor receptor | 0.0352373 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0346637 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0339851 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0319778 |
| DTNA | dystrobrevin, alpha | 0.0318926 |
| SMAD3 | SMAD family member 3 | 0.0318701 |
| FAM13A | family with sequence similarity 13, member A | 0.0315821 |
| HELZ | helicase with zinc finger | 0.0308875 |
| ZNF638 | zinc finger protein 638 | 0.0304897 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0288468 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0277452 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0266545 |
| EGR1 | early growth response 1 | 0.0262247 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0255984 |
| SRP54 | signal recognition particle 54kDa | 0.0244616 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0243661 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0241754 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0240663 |
| GOLGA4 | golgin A4 | 0.0237195 |
| C1S | complement component 1, s subcomponent | 0.023565 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.0223603 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0222826 |
| PRELID2 | PRELI domain containing 2 | 0.0222348 |
| SFTPA2 | surfactant protein A2 | 0.0221979 |
| ZNF841 | zinc finger protein 841 | 0.0219983 |
| KYNU | kynureninase | 0.021893 |
| ASPH | aspartate beta-hydroxylase | 0.0210796 |
| MAF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog | 0.0210617 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0210576 |
| ZNF395 | zinc finger protein 395 | 0.020917 |
| GLIS3 | GLIS family zinc finger 3 | 0.0206827 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0206444 |
| JMJD1C | jumonji domain containing 1C | 0.0205774 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0203313 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0200662 |
| SEC24A | SEC24 family member A | 0.0197332 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0196726 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0195581 |
| ARFGEF3 | ARFGEF family member 3 | 0.0192839 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0191578 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.019143 |
| RASA2 | RAS p21 protein activator 2 | 0.0186628 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | 0.0183267 |
| CLEC1B | C-type lectin domain family 1, member B | 0.0181088 |
| SUCO | SUN domain containing ossification factor | 0.01807 |
| PGM3 | phosphoglucomutase 3 | 0.0178094 |
| PLIN2 | perilipin 2 | 0.0177965 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.017637 |
| GOLGB1 | golgin B1 | 0.0176243 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.017511 |
| SQSTM1 | sequestosome 1 | 0.0174593 |
| CALN1 | calneuron 1 | 0.0173974 |
| NGLY1 | N-glycanase 1 | 0.017216 |
| RUNX1 | runt-related transcription factor 1 | 0.0172076 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0171874 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0171815 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.017157 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | 0.0169701 |
| UBAP2 | ubiquitin associated protein 2 | 0.0169688 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0169387 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0168654 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0167614 |
| ITGB3BP | integrin beta 3 binding protein (beta3-endonexin) | 0.0166301 |
| ELP2 | elongator acetyltransferase complex subunit 2 | 0.0165719 |
| ANXA5 | annexin A5 | 0.0164963 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0162175 |
| GYS1 | glycogen synthase 1 (muscle) | 0.0161287 |
| HDAC9 | histone deacetylase 9 | 0.0161062 |
| NCOA7 | nuclear receptor coactivator 7 | 0.0156481 |
| GPHN | gephyrin | 0.0155591 |
| SLC39A11 | solute carrier family 39, member 11 | 0.0154964 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0153943 |
| METTL15 | methyltransferase like 15 | 0.0153796 |
| PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) | 0.0152466 |
| ZNF160 | zinc finger protein 160 | 0.0152308 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.0151632 |
| XKR6 | XK, Kell blood group complex subunit-related family, member 6 | 0.0151206 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0151158 |
| TAF4B | TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa | 0.0149921 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0149094 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0148193 |
| USP9Y | ubiquitin specific peptidase 9, Y-linked | 0.0147877 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0146999 |
| SNX14 | sorting nexin 14 | 0.0146811 |
| VPS13C | vacuolar protein sorting 13 homolog C (S. cerevisiae) | 0.0145466 |
| ARRDC3 | arrestin domain containing 3 | 0.014546 |
| ANO6 | anoctamin 6 | 0.0144965 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0142423 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | 0.0140943 |
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | -0.138042 |
| TMSB10 | thymosin beta 10 | -0.123413 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.114387 |
| FN1 | fibronectin 1 | -0.113378 |
| PTMA | prothymosin, alpha | -0.0825297 |
| TPM4 | tropomyosin 4 | -0.0751671 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0723067 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0605209 |
| NLGN1 | neuroligin 1 | -0.0589965 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0546458 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0545269 |
| DST | dystonin | -0.0538508 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0528346 |
| VIM | vimentin | -0.0527089 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0519172 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0512359 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0496336 |
| MKI67 | marker of proliferation Ki-67 | -0.048692 |
| AHNAK | AHNAK nucleoprotein | -0.0475098 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0470865 |
| HLA-B | major histocompatibility complex, class I, B | -0.0467397 |
| CALR | calreticulin | -0.0461516 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0460927 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0454907 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0415689 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0411391 |
| CENPF | centromere protein F, 350/400kDa | -0.0409708 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0409585 |
| POTEF | POTE ankyrin domain family, member F | -0.0404738 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0385696 |
| IGF2 | insulin-like growth factor 2 | -0.0374886 |
| FTL | ferritin, light polypeptide | -0.0352813 |
| TCF12 | transcription factor 12 | -0.0352026 |
| RPS6 | ribosomal protein S6 | -0.034287 |
| MT2A | metallothionein 2A | -0.0336084 |
| VCL | vinculin | -0.0335357 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0332028 |
| H3-3B | H3.3 histone B | -0.0324828 |
| TNNC1 | troponin C type 1 (slow) | -0.03119 |
| PRSS23 | protease, serine, 23 | -0.0302387 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0301932 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.029803 |
| PRRC2C | proline-rich coiled-coil 2C | -0.029796 |
| RPL35A | ribosomal protein L35a | -0.0293978 |
| S100A6 | S100 calcium binding protein A6 | -0.0291815 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0290582 |
| MAP1B | microtubule-associated protein 1B | -0.0289076 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0284863 |
| EYA4 | EYA transcriptional coactivator and phosphatase 4 | -0.0280682 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0277497 |
| RTN4 | reticulon 4 | -0.0275796 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.027528 |
| HLA-A | major histocompatibility complex, class I, A | -0.0271559 |
| ANLN | anillin, actin binding protein | -0.0269934 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0260474 |
| RPS3 | ribosomal protein S3 | -0.0253098 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0251465 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0248266 |
| CKAP4 | cytoskeleton-associated protein 4 | -0.0242881 |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B | -0.0242419 |
| LMNA | lamin A/C | -0.0237894 |
| TUBB | tubulin, beta class I | -0.0236325 |
| MAP4 | microtubule-associated protein 4 | -0.023556 |
| GNAS | GNAS complex locus | -0.0232927 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0231877 |
| NSD2 | nuclear receptor binding SET domain protein 2 | -0.0231105 |
| PGK1 | phosphoglycerate kinase 1 | -0.0229657 |
| TPI1 | triosephosphate isomerase 1 | -0.0229457 |
| RPLP2 | ribosomal protein, large, P2 | -0.0229119 |
| RPL37 | ribosomal protein L37 | -0.0228623 |
| LAMB1 | laminin, beta 1 | -0.022859 |
| CENPE | centromere protein E, 312kDa | -0.0228455 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0228202 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0227947 |
| UBE2K | ubiquitin-conjugating enzyme E2K | -0.0225254 |
| CLMP | CXADR-like membrane protein | -0.0224888 |
| HIBADH | 3-hydroxyisobutyrate dehydrogenase | -0.0224061 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0223863 |
| SEPTIN7 | septin 7 | -0.0223823 |
| PSMD1 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 | -0.0220186 |
| PKM | pyruvate kinase, muscle | -0.0217914 |
| CBX3 | chromobox homolog 3 | -0.0216625 |
| RNF216 | ring finger protein 216 | -0.0214075 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0214054 |
| CAVIN1 | caveolae associated protein 1 | -0.0212806 |
| SBF2 | SET binding factor 2 | -0.0209607 |
| COL5A2 | collagen, type V, alpha 2 | -0.0209372 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.0209172 |
| TXNRD1 | thioredoxin reductase 1 | -0.0208402 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0207866 |
| LYPD6B | LY6/PLAUR domain containing 6B | -0.0206461 |
| RPL7A | ribosomal protein L7a | -0.020637 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | -0.0206107 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0206087 |
| CREB5 | cAMP responsive element binding protein 5 | -0.0205282 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0204431 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0203875 |
| PTCHD4 | patched domain containing 4 | -0.0203376 |
| AHCYL1 | adenosylhomocysteinase-like 1 | -0.0203353 |
| BDP1 | B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB | -0.0203116 |
