| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | ULK-101 perturbation in HCT15 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the ULK-101_HCT15 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.191323 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.148438 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.1245 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.101045 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0921912 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0814605 |
| CANX | calnexin | 0.0709925 |
| MCL1 | myeloid cell leukemia 1 | 0.0694187 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0664528 |
| INTS6 | integrator complex subunit 6 | 0.0572117 |
| EGR1 | early growth response 1 | 0.054123 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.051886 |
| PCBP2 | poly(rC) binding protein 2 | 0.0504376 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0457062 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0453571 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0446395 |
| GOLGA4 | golgin A4 | 0.0428502 |
| SQSTM1 | sequestosome 1 | 0.042828 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0417158 |
| PRELID2 | PRELI domain containing 2 | 0.0415852 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0415255 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0399971 |
| HYOU1 | hypoxia up-regulated 1 | 0.0395031 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | 0.0392473 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0387072 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0385085 |
| LRRC23 | leucine rich repeat containing 23 | 0.0380247 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.037709 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0367854 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0366216 |
| TXNRD1 | thioredoxin reductase 1 | 0.0359513 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0358008 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0357887 |
| HDLBP | high density lipoprotein binding protein | 0.0353563 |
| JUN | jun proto-oncogene | 0.0345362 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.034471 |
| COG6 | component of oligomeric golgi complex 6 | 0.0342676 |
| SEC24D | SEC24 family member D | 0.0342324 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0337739 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0332414 |
| TJP1 | tight junction protein 1 | 0.0330699 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | 0.032728 |
| SON | SON DNA binding protein | 0.0322106 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0321338 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.0320147 |
| VMP1 | vacuole membrane protein 1 | 0.0317084 |
| RIOK3 | RIO kinase 3 | 0.0312175 |
| TMF1 | TATA element modulatory factor 1 | 0.0311827 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0305252 |
| GOLGB1 | golgin B1 | 0.0302555 |
| SEC24A | SEC24 family member A | 0.029828 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0296932 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0294816 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0293444 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0287542 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0282463 |
| EIF2AK1 | eukaryotic translation initiation factor 2-alpha kinase 1 | 0.0282195 |
| SPTY2D1 | SPT2, Suppressor of Ty, domain containing 1 (S. cerevisiae) | 0.0277809 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0276118 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.027555 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0274715 |
| SEPTIN2 | septin 2 | 0.0272724 |
| BBS9 | Bardet-Biedl syndrome 9 | 0.0271723 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0269553 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0267017 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0263494 |
| CPEB3 | cytoplasmic polyadenylation element binding protein 3 | 0.0263162 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.026252 |
| RSRP1 | arginine/serine-rich protein 1 | 0.0262429 |
| ARL5B | ADP-ribosylation factor-like 5B | 0.0260232 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0259654 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0258197 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.025643 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | 0.0256293 |
| POU2F2 | POU class 2 homeobox 2 | 0.025624 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0255887 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0255505 |
| HM13 | histocompatibility (minor) 13 | 0.0250277 |
| SETX | senataxin | 0.0248389 |
| LMAN1 | lectin, mannose-binding, 1 | 0.0245292 |
| FNIP1 | folliculin interacting protein 1 | 0.0244933 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0243024 |
| RUNX1 | runt-related transcription factor 1 | 0.0240587 |
| UBN2 | ubinuclein 2 | 0.0238268 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0237961 |
| SKP1 | S-phase kinase-associated protein 1 | 0.0237884 |
| SUCO | SUN domain containing ossification factor | 0.0237567 |
| CCDC186 | coiled-coil domain containing 186 | 0.0236751 |
| MORF4L2 | mortality factor 4 like 2 | 0.0234458 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0233446 |
| FOCAD | focadhesin | 0.0232444 |
| LDHA | lactate dehydrogenase A | 0.0231838 |
| YAP1 | Yes-associated protein 1 | 0.0229129 |
| TBC1D15 | TBC1 domain family, member 15 | 0.0223323 |
| UFM1 | ubiquitin-fold modifier 1 | 0.0221835 |
| LARGE1 | LARGE xylosyl- and glucuronyltransferase 1 | 0.0221641 |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | 0.022142 |
| TLN1 | talin 1 | 0.0221238 |
| TFG | TRK-fused gene | 0.0219022 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0218359 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | -0.197173 |
| PTMA | prothymosin, alpha | -0.151639 |
| FAT1 | FAT atypical cadherin 1 | -0.141102 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.131668 |
| TMSB10 | thymosin beta 10 | -0.0765781 |
| AHNAK | AHNAK nucleoprotein | -0.0602539 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0569337 |
| MKI67 | marker of proliferation Ki-67 | -0.0565304 |
| KRT18 | keratin 18, type I | -0.0559842 |
| RPL35A | ribosomal protein L35a | -0.0514165 |
| RPL26 | ribosomal protein L26 | -0.0501032 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0448665 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.043956 |
| DIAPH2 | diaphanous-related formin 2 | -0.0423806 |
| EPCAM | epithelial cell adhesion molecule | -0.0417 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0414758 |
| RPL37A | ribosomal protein L37a | -0.038673 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0377998 |
| ACTN4 | actinin, alpha 4 | -0.0377778 |
| PKM | pyruvate kinase, muscle | -0.036321 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0362393 |
| HMGA2 | high mobility group AT-hook 2 | -0.0362285 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.0347382 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0342243 |
| HLA-B | major histocompatibility complex, class I, B | -0.0333825 |
| MSI2 | musashi RNA-binding protein 2 | -0.0332154 |
| SH3BP4 | SH3-domain binding protein 4 | -0.0330159 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0323838 |
| SMC4 | structural maintenance of chromosomes 4 | -0.03213 |
| ACTG1 | actin gamma 1 | -0.0318663 |
| CCND1 | cyclin D1 | -0.0317344 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0315069 |
| RPL37 | ribosomal protein L37 | -0.0310039 |
| RPS3 | ribosomal protein S3 | -0.0305534 |
| LMNA | lamin A/C | -0.0302867 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | -0.0302032 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0301669 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0300838 |
| RBM25 | RNA binding motif protein 25 | -0.0300454 |
| S100A6 | S100 calcium binding protein A6 | -0.0298775 |
| CD2AP | CD2-associated protein | -0.0294284 |
| TPM4 | tropomyosin 4 | -0.0292664 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.029213 |
| SET | SET nuclear proto-oncogene | -0.0291728 |
| MT2A | metallothionein 2A | -0.0281691 |
| RPS6 | ribosomal protein S6 | -0.0280967 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0280539 |
| CHD6 | chromodomain helicase DNA binding protein 6 | -0.0274292 |
| ARMH4 | armadillo like helical domain containing 4 | -0.0273556 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0271279 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0271032 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0266728 |
| RAD51B | RAD51 paralog B | -0.026639 |
| RHPN2 | rhophilin, Rho GTPase binding protein 2 | -0.0266342 |
| RPLP2 | ribosomal protein, large, P2 | -0.0265605 |
| RPS27A | ribosomal protein S27a | -0.0261646 |
| PTK2 | protein tyrosine kinase 2 | -0.0261406 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.025964 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0255143 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0253373 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0251786 |
| ZHX2 | zinc fingers and homeoboxes 2 | -0.0250697 |
| FRAS1 | Fraser extracellular matrix complex subunit 1 | -0.0246439 |
| FNBP4 | formin binding protein 4 | -0.024635 |
| GPBP1L1 | GC-rich promoter binding protein 1-like 1 | -0.024615 |
| CORO1C | coronin, actin binding protein, 1C | -0.0241799 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.02407 |
| CMIP | c-Maf inducing protein | -0.023809 |
| ITGB4 | integrin, beta 4 | -0.0237043 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0235326 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0233424 |
| S100A9 | S100 calcium binding protein A9 | -0.0232559 |
| APOLD1 | apolipoprotein L domain containing 1 | -0.0231518 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.0231353 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0230593 |
| CENPF | centromere protein F, 350/400kDa | -0.0230344 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0230108 |
| KDM7A | lysine (K)-specific demethylase 7A | -0.0229324 |
| DENND4C | DENN/MADD domain containing 4C | -0.0227529 |
| TUBB | tubulin, beta class I | -0.0227316 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0226223 |
| ZFHX3 | zinc finger homeobox 3 | -0.0224073 |
| RNF43 | ring finger protein 43 | -0.0223099 |
| TCF12 | transcription factor 12 | -0.0222788 |
| CLOCK | clock circadian regulator | -0.0222736 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0221056 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0220654 |
| CD46 | CD46 molecule, complement regulatory protein | -0.022002 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0219342 |
| FDPS | farnesyl diphosphate synthase | -0.021933 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0218181 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0216972 |
| H1-0 | H1.0 linker histone | -0.0216691 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | -0.021562 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | -0.0213944 |
| NOP56 | NOP56 ribonucleoprotein | -0.0213167 |
| TUBA1B | tubulin, alpha 1b | -0.0212898 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | -0.0212603 |
| ANLN | anillin, actin binding protein | -0.0212096 |
| DYNC2I1 | dynein 2 intermediate chain 1 | -0.0211859 |
