| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | ULK-101 perturbation in HEC-1-A cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the ULK-101_HEC-1-A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0625823 |
| B2M | beta-2-microglobulin | 0.0414218 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0410376 |
| GOLGA4 | golgin A4 | 0.035313 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0324089 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0313066 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0303092 |
| RPL12 | ribosomal protein L12 | 0.0298834 |
| SNX9 | sorting nexin 9 | 0.0269435 |
| RPS8 | ribosomal protein S8 | 0.0268948 |
| RPL18 | ribosomal protein L18 | 0.0263473 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0263364 |
| PCBP2 | poly(rC) binding protein 2 | 0.026312 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0262287 |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit | 0.0259437 |
| SET | SET nuclear proto-oncogene | 0.0252625 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0252574 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0247523 |
| RPLP0 | ribosomal protein, large, P0 | 0.0242827 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0238281 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0234351 |
| TXNRD1 | thioredoxin reductase 1 | 0.0231286 |
| MATR3 | matrin 3 | 0.0221295 |
| YBX1 | Y box binding protein 1 | 0.0215515 |
| ECT2 | epithelial cell transforming 2 | 0.0207684 |
| RPL32 | ribosomal protein L32 | 0.0206446 |
| SPAG9 | sperm associated antigen 9 | 0.020443 |
| TJP1 | tight junction protein 1 | 0.0199327 |
| MT2A | metallothionein 2A | 0.0198724 |
| RACK1 | receptor for activated C kinase 1 | 0.0196321 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0192257 |
| CYSTM1 | cysteine-rich transmembrane module containing 1 | 0.0192065 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0189263 |
| HELZ | helicase with zinc finger | 0.0186273 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0180924 |
| RPS12 | ribosomal protein S12 | 0.0180364 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0178499 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0174646 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.0173478 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0173187 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0172105 |
| GOLGB1 | golgin B1 | 0.0171803 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0170885 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0170851 |
| FTL | ferritin, light polypeptide | 0.0170494 |
| COG5 | component of oligomeric golgi complex 5 | 0.0169528 |
| SFTPA2 | surfactant protein A2 | 0.0168809 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0168756 |
| IPO7 | importin 7 | 0.0168107 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0166624 |
| RPS2 | ribosomal protein S2 | 0.0166554 |
| EXOC6B | exocyst complex component 6B | 0.0166154 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0166072 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0165715 |
| SGMS2 | sphingomyelin synthase 2 | 0.0165536 |
| RPL7 | ribosomal protein L7 | 0.0160442 |
| RASA2 | RAS p21 protein activator 2 | 0.0158742 |
| TPM3 | tropomyosin 3 | 0.0158275 |
| DIAPH1 | diaphanous-related formin 1 | 0.0158242 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0158052 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0157101 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0156941 |
| CCNL1 | cyclin L1 | 0.0155777 |
| NCKAP1 | NCK-associated protein 1 | 0.0155626 |
| SQSTM1 | sequestosome 1 | 0.0153851 |
| CREBRF | CREB3 regulatory factor | 0.0152304 |
| COG6 | component of oligomeric golgi complex 6 | 0.0151904 |
| KLHL24 | kelch-like family member 24 | 0.0151265 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0150455 |
| RPS5 | ribosomal protein S5 | 0.0149494 |
| RPS19 | ribosomal protein S19 | 0.0149031 |
| AXL | AXL receptor tyrosine kinase | 0.0148522 |
| RPS14 | ribosomal protein S14 | 0.0146956 |
| SMAD3 | SMAD family member 3 | 0.014623 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0144427 |
| ZNF292 | zinc finger protein 292 | 0.0144357 |
| KDELR1 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 | 0.0142873 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0142106 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0141763 |
| RPL35 | ribosomal protein L35 | 0.0141441 |
| SPOPL | speckle-type POZ protein-like | 0.013981 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.0139779 |
| MYADM | myeloid-associated differentiation marker | 0.0137503 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.013715 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0137124 |
| ITSN2 | intersectin 2 | 0.0135896 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.013579 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0135728 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0135672 |
| ITM2B | integral membrane protein 2B | 0.0135216 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.0134163 |
| NR1D2 | nuclear receptor subfamily 1, group D, member 2 | 0.0134084 |
| RIOK3 | RIO kinase 3 | 0.0133322 |
| HERC1 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 | 0.0132751 |
| TBC1D15 | TBC1 domain family, member 15 | 0.0132006 |
| KIF1B | kinesin family member 1B | 0.0131896 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0131806 |
| NEK7 | NIMA-related kinase 7 | 0.0131788 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0130828 |
| VMP1 | vacuole membrane protein 1 | 0.0130452 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0781466 |
| PRELID2 | PRELI domain containing 2 | -0.0766231 |
| TMSB10 | thymosin beta 10 | -0.0693746 |
| ASPH | aspartate beta-hydroxylase | -0.0648429 |
| PTMA | prothymosin, alpha | -0.0633312 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0614954 |
| NDRG1 | N-myc downstream regulated 1 | -0.0606405 |
| RAD51B | RAD51 paralog B | -0.0546389 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.052032 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0514177 |
| RHEX | regulator of hemoglobinization and erythroid cell expansion | -0.0507764 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0491212 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0489655 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0483461 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0473063 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.047092 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0468823 |
| LAMB3 | laminin, beta 3 | -0.0447544 |
| AHNAK | AHNAK nucleoprotein | -0.043378 |
| MAP4 | microtubule-associated protein 4 | -0.0426138 |
| FHIT | fragile histidine triad | -0.042502 |
| DSCAML1 | Down syndrome cell adhesion molecule like 1 | -0.0421341 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0416585 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0413996 |
| VCL | vinculin | -0.0413693 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0377633 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.036528 |
| PAX8 | paired box 8 | -0.0359024 |
| SVIL | supervillin | -0.0349516 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0348862 |
| OSBPL10 | oxysterol binding protein-like 10 | -0.0342253 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0340014 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0335566 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0332145 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -0.0327744 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0325283 |
| PCED1B | PC-esterase domain containing 1B | -0.0323468 |
| LDHA | lactate dehydrogenase A | -0.0319293 |
| FLNB | filamin B, beta | -0.0317934 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0312833 |
| HMGA2 | high mobility group AT-hook 2 | -0.0311252 |
| DENND1A | DENN/MADD domain containing 1A | -0.0310303 |
| RPL35A | ribosomal protein L35a | -0.0305011 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0301684 |
| MKI67 | marker of proliferation Ki-67 | -0.029104 |
| CCND1 | cyclin D1 | -0.0286652 |
| EGFR | epidermal growth factor receptor | -0.0282946 |
| DIAPH3 | diaphanous-related formin 3 | -0.0282946 |
| ATG7 | autophagy related 7 | -0.0279598 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0277122 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0275818 |
| ZFHX3 | zinc finger homeobox 3 | -0.0273934 |
| CD44 | CD44 molecule (Indian blood group) | -0.0272488 |
| WWOX | WW domain containing oxidoreductase | -0.0268405 |
| POU5F1 | POU class 5 homeobox 1 | -0.0268327 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.026494 |
| NSD2 | nuclear receptor binding SET domain protein 2 | -0.0262239 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0254787 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0254084 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0253974 |
| H1-0 | H1.0 linker histone | -0.0253547 |
| ACTG1 | actin gamma 1 | -0.0249086 |
| ANXA3 | annexin A3 | -0.0247944 |
| FRAS1 | Fraser extracellular matrix complex subunit 1 | -0.0245365 |
| RPL38 | ribosomal protein L38 | -0.0244426 |
| FLNA | filamin A, alpha | -0.0241777 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0238763 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0238005 |
| NDUFAF2 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 2 | -0.0236585 |
| GNAS | GNAS complex locus | -0.0236154 |
| SMYD3 | SET and MYND domain containing 3 | -0.023605 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | -0.0230853 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0230011 |
| CMIP | c-Maf inducing protein | -0.0222501 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0221866 |
| ACTN4 | actinin, alpha 4 | -0.0221127 |
| HMGB1 | high mobility group box 1 | -0.0218311 |
| DPP4 | dipeptidyl-peptidase 4 | -0.0217691 |
| APOLD1 | apolipoprotein L domain containing 1 | -0.0215396 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0215218 |
| VCAN | versican | -0.0215117 |
| EHBP1 | EH domain binding protein 1 | -0.0214607 |
| KRT19 | keratin 19, type I | -0.0213904 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.0213667 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0210965 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0210475 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.0209677 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.020592 |
| LARP1 | La ribonucleoprotein domain family, member 1 | -0.0205264 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0205097 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0204765 |
| EFCAB13 | EF-hand calcium binding domain 13 | -0.0202681 |
| ZRANB3 | zinc finger, RAN-binding domain containing 3 | -0.0202513 |
| PRKCA | protein kinase C, alpha | -0.0201168 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0201108 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | -0.0200205 |
| PLEC | plectin | -0.0198505 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | -0.0198364 |
| LASP1 | LIM and SH3 protein 1 | -0.0198219 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0197628 |
