| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | ULK-101 perturbation in HT-29 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the ULK-101_HT-29 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | 0.167206 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.150493 |
| FTL | ferritin, light polypeptide | 0.127092 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0953467 |
| TJP1 | tight junction protein 1 | 0.0826456 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0817891 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0801718 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0746308 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0605048 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0575126 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.055348 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0549581 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0541402 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0532479 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.051952 |
| RPS6 | ribosomal protein S6 | 0.0512095 |
| CANX | calnexin | 0.0510921 |
| B2M | beta-2-microglobulin | 0.0489643 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.047748 |
| FOXP1 | forkhead box P1 | 0.0474636 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.046949 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.0455469 |
| ATXN1 | ataxin 1 | 0.0442578 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0441968 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0438989 |
| PTMA | prothymosin, alpha | 0.0431113 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0429039 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0425656 |
| GOLGA4 | golgin A4 | 0.0419633 |
| RPLP0 | ribosomal protein, large, P0 | 0.041751 |
| RPS8 | ribosomal protein S8 | 0.0405849 |
| RPS13 | ribosomal protein S13 | 0.0389853 |
| LYZ | lysozyme | 0.037271 |
| EGFR | epidermal growth factor receptor | 0.0372651 |
| CALR | calreticulin | 0.036304 |
| NTN4 | netrin 4 | 0.0360245 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.035517 |
| LIMA1 | LIM domain and actin binding 1 | 0.0352806 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.0352012 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | 0.0351968 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0351067 |
| DST | dystonin | 0.0338223 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0332605 |
| HDLBP | high density lipoprotein binding protein | 0.0328798 |
| HYOU1 | hypoxia up-regulated 1 | 0.0323829 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0323132 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0321226 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0318272 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0315069 |
| ENO1 | enolase 1, (alpha) | 0.0312994 |
| UTRN | utrophin | 0.0312852 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.031245 |
| GCC2 | GRIP and coiled-coil domain containing 2 | 0.0310715 |
| KRT18 | keratin 18, type I | 0.0307791 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0305865 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0305101 |
| ASTN2 | astrotactin 2 | 0.0301773 |
| PGK1 | phosphoglycerate kinase 1 | 0.0301769 |
| MYO1E | myosin IE | 0.030167 |
| SIK3 | SIK family kinase 3 | 0.0299121 |
| RPL27A | ribosomal protein L27a | 0.0297675 |
| TMC5 | transmembrane channel-like 5 | 0.0294932 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0292985 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.028686 |
| RPL31 | ribosomal protein L31 | 0.0284992 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0281609 |
| LDHA | lactate dehydrogenase A | 0.0281357 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0279386 |
| MTDH | metadherin | 0.0278714 |
| MLEC | malectin | 0.0277662 |
| RPL23 | ribosomal protein L23 | 0.0277533 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0274045 |
| RPS3 | ribosomal protein S3 | 0.0271692 |
| PDE10A | phosphodiesterase 10A | 0.0270431 |
| TRAM1 | translocation associated membrane protein 1 | 0.0268732 |
| RPS16 | ribosomal protein S16 | 0.026538 |
| KPNB1 | karyopherin (importin) beta 1 | 0.026537 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | 0.0263316 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0262153 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.0261889 |
| RPLP1 | ribosomal protein, large, P1 | 0.0260828 |
| RACK1 | receptor for activated C kinase 1 | 0.0260235 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0259784 |
| UBC | ubiquitin C | 0.0256436 |
| RPS12 | ribosomal protein S12 | 0.0256062 |
| RPL7 | ribosomal protein L7 | 0.0247017 |
| RPL7A | ribosomal protein L7a | 0.0245935 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0245654 |
| ERBIN | erbb2 interacting protein | 0.0244879 |
| PDZD8 | PDZ domain containing 8 | 0.0240789 |
| RPS23 | ribosomal protein S23 | 0.0240101 |
| HM13 | histocompatibility (minor) 13 | 0.0240088 |
| RPS25 | ribosomal protein S25 | 0.0239766 |
| MYADM | myeloid-associated differentiation marker | 0.0238723 |
| JMY | junction mediating and regulatory protein, p53 cofactor | 0.0236253 |
| LCOR | ligand dependent nuclear receptor corepressor | 0.0231665 |
| RPL12 | ribosomal protein L12 | 0.0229971 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.02265 |
| S100A6 | S100 calcium binding protein A6 | 0.0223891 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0221783 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | -0.0903917 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.0847891 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.0714913 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0687421 |
| SLC45A4 | solute carrier family 45, member 4 | -0.0668693 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0656837 |
| PRELID2 | PRELI domain containing 2 | -0.0634421 |
| ACTN4 | actinin, alpha 4 | -0.0623764 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0521196 |
| INTS6 | integrator complex subunit 6 | -0.0437012 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0398123 |
| VCL | vinculin | -0.0395181 |
| TUFT1 | tuftelin 1 | -0.0378116 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0377459 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0368731 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0360187 |
| KRT8 | keratin 8, type II | -0.0347929 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0336438 |
| ATAD2 | ATPase family, AAA domain containing 2 | -0.0332161 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0313507 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0312127 |
| AHNAK | AHNAK nucleoprotein | -0.0311498 |
| RBM39 | RNA binding motif protein 39 | -0.0305525 |
| EZR | ezrin | -0.0297726 |
| STK24 | serine/threonine kinase 24 | -0.0295337 |
| MCL1 | myeloid cell leukemia 1 | -0.0291684 |
| PLEC | plectin | -0.0280584 |
| SBF2 | SET binding factor 2 | -0.0275554 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0268799 |
| OGA | O-GlcNAcase | -0.0267034 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0263911 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0254101 |
| ANXA2 | annexin A2 | -0.0252173 |
| FOXO3 | forkhead box O3 | -0.0251547 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0247494 |
| JUP | junction plakoglobin | -0.0245972 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0245875 |
| TRIB1 | tribbles pseudokinase 1 | -0.023748 |
| HOXB3 | homeobox B3 | -0.0236387 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0233084 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0232768 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0221682 |
| MYO18A | myosin XVIIIA | -0.0220681 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0220269 |
| IFRD1 | interferon-related developmental regulator 1 | -0.021902 |
| CCNL1 | cyclin L1 | -0.0215717 |
| FRY | furry homolog (Drosophila) | -0.0214187 |
| ANXA11 | annexin A11 | -0.0212315 |
| GSN | gelsolin | -0.0209284 |
| SDCBP | syndecan binding protein (syntenin) | -0.0208738 |
| PCED1B | PC-esterase domain containing 1B | -0.0207267 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.020654 |
| SQSTM1 | sequestosome 1 | -0.020503 |
| LSR | lipolysis stimulated lipoprotein receptor | -0.0204751 |
| EGR1 | early growth response 1 | -0.0203864 |
| BAIAP2 | BAI1-associated protein 2 | -0.0197721 |
| LASP1 | LIM and SH3 protein 1 | -0.0196292 |
| MYO1D | myosin ID | -0.0193943 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -0.0188553 |
| KDM4B | lysine (K)-specific demethylase 4B | -0.0187215 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | -0.0186378 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0184258 |
| SERTAD2 | SERTA domain containing 2 | -0.0183854 |
| LNX2 | ligand of numb-protein X 2 | -0.0183632 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0183515 |
| NUP98 | nucleoporin 98kDa | -0.0183039 |
| MTAP | methylthioadenosine phosphorylase | -0.0181506 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.0176628 |
| ITGB4 | integrin, beta 4 | -0.0176527 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0175485 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0174066 |
| ITPKC | inositol-trisphosphate 3-kinase C | -0.017395 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0172719 |
| NCOA2 | nuclear receptor coactivator 2 | -0.0172479 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0172252 |
| SH3BP2 | SH3-domain binding protein 2 | -0.0172127 |
| GNGT1 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 | -0.0171784 |
| RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 | -0.0167932 |
| USP53 | ubiquitin specific peptidase 53 | -0.0167821 |
| CHKA | choline kinase alpha | -0.0167135 |
| H1-0 | H1.0 linker histone | -0.0166847 |
| PRKCE | protein kinase C, epsilon | -0.0166827 |
| ADD1 | adducin 1 (alpha) | -0.0166424 |
| WDR1 | WD repeat domain 1 | -0.0166226 |
| HMGB1 | high mobility group box 1 | -0.0165312 |
| IGF1R | insulin-like growth factor 1 receptor | -0.016449 |
| ECT2 | epithelial cell transforming 2 | -0.0163077 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.016306 |
| NECTIN2 | nectin cell adhesion molecule 2 | -0.0161752 |
| SDC4 | syndecan 4 | -0.0161254 |
| LMNA | lamin A/C | -0.0158231 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0157725 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0157078 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | -0.0156745 |
| PDE8A | phosphodiesterase 8A | -0.0156555 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0156223 |
| RNF213 | ring finger protein 213 | -0.0155315 |
| GNAS | GNAS complex locus | -0.015502 |
| PPP1R10 | protein phosphatase 1, regulatory subunit 10 | -0.0154509 |
| CAPN8 | calpain 8 | -0.0152898 |
