| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | ULK-101 perturbation in J82 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the ULK-101_J82 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.193528 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.114228 |
| FN1 | fibronectin 1 | 0.107208 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0998958 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0961298 |
| ASPH | aspartate beta-hydroxylase | 0.0882548 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0882085 |
| ENO1 | enolase 1, (alpha) | 0.0864825 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0842549 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0811494 |
| ERBIN | erbb2 interacting protein | 0.0806893 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0778449 |
| NAV2 | neuron navigator 2 | 0.0744394 |
| FNDC3B | fibronectin type III domain containing 3B | 0.067984 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.06602 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.065328 |
| INTS6 | integrator complex subunit 6 | 0.0632057 |
| DTNA | dystrobrevin, alpha | 0.0627233 |
| CD44 | CD44 molecule (Indian blood group) | 0.0596525 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0581931 |
| PHACTR1 | phosphatase and actin regulator 1 | 0.0569685 |
| DST | dystonin | 0.0568447 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0567857 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.055056 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0542401 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0512129 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0492268 |
| CANX | calnexin | 0.0491017 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0490353 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0489882 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0489378 |
| EGFR | epidermal growth factor receptor | 0.0486804 |
| TLE4 | transducin-like enhancer of split 4 | 0.0484562 |
| LDHA | lactate dehydrogenase A | 0.0483006 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0477145 |
| ZNF432 | zinc finger protein 432 | 0.0462944 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0458172 |
| POTEF | POTE ankyrin domain family, member F | 0.0457513 |
| ATXN1 | ataxin 1 | 0.0453036 |
| VIM | vimentin | 0.0443151 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | 0.0438555 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0419203 |
| VCL | vinculin | 0.041142 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0406942 |
| FNIP1 | folliculin interacting protein 1 | 0.0403097 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0402115 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0389089 |
| RND3 | Rho family GTPase 3 | 0.0388747 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0387679 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.038308 |
| SMYD3 | SET and MYND domain containing 3 | 0.0377853 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0376854 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0371774 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0364878 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0364148 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0363359 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0361405 |
| GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 | 0.0360697 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0359844 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0359455 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0357266 |
| TPM4 | tropomyosin 4 | 0.0357157 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0354506 |
| RAD51B | RAD51 paralog B | 0.0351335 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0350868 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0344322 |
| GOLGB1 | golgin B1 | 0.0341937 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0341127 |
| C6ORF62 | chromosome 6 open reading frame 62 | 0.0340494 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0338349 |
| SETX | senataxin | 0.0336474 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0332302 |
| UBAP2 | ubiquitin associated protein 2 | 0.0328219 |
| TPM3 | tropomyosin 3 | 0.0328119 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0327194 |
| SQSTM1 | sequestosome 1 | 0.0326048 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0319333 |
| MSN | moesin | 0.0319246 |
| RAI14 | retinoic acid induced 14 | 0.0314879 |
| PCBP2 | poly(rC) binding protein 2 | 0.0310574 |
| ACTG1 | actin gamma 1 | 0.0310433 |
| CUX1 | cut-like homeobox 1 | 0.0309719 |
| MYO1E | myosin IE | 0.0306176 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0300694 |
| HDAC9 | histone deacetylase 9 | 0.030011 |
| PLSCR1 | phospholipid scramblase 1 | 0.0299699 |
| NDRG1 | N-myc downstream regulated 1 | 0.0299057 |
| FHIT | fragile histidine triad | 0.0297842 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0297566 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | 0.0297445 |
| SET | SET nuclear proto-oncogene | 0.0295489 |
| VEGFC | vascular endothelial growth factor C | 0.0292647 |
| MMP12 | matrix metallopeptidase 12 | 0.029107 |
| FAM107B | family with sequence similarity 107, member B | 0.0290567 |
| ACTN1 | actinin, alpha 1 | 0.0290456 |
| PRELID2 | PRELI domain containing 2 | 0.0289312 |
| RUNX1 | runt-related transcription factor 1 | 0.0288792 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0284038 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | 0.0280563 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0278551 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FTL | ferritin, light polypeptide | -0.113115 |
| HLA-B | major histocompatibility complex, class I, B | -0.108746 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0781962 |
| MT1X | metallothionein 1X | -0.0665616 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0641384 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0623758 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0535112 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0406351 |
| SLC12A8 | solute carrier family 12, member 8 | -0.0398499 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0378765 |
| DEK | DEK proto-oncogene | -0.0374944 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0315224 |
| POSTN | periostin, osteoblast specific factor | -0.0313984 |
| ADM | adrenomedullin | -0.0312262 |
| ANKRD10 | ankyrin repeat domain 10 | -0.030776 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0293604 |
| TPD52 | tumor protein D52 | -0.0286871 |
| USP3 | ubiquitin specific peptidase 3 | -0.0283593 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.027443 |
| RPL35A | ribosomal protein L35a | -0.0266143 |
| TGFB2 | transforming growth factor, beta 2 | -0.0264068 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0264043 |
| PPME1 | protein phosphatase methylesterase 1 | -0.025968 |
| ARF4 | ADP-ribosylation factor 4 | -0.0255737 |
| TUBB | tubulin, beta class I | -0.0252983 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | -0.0249547 |
| RLF | rearranged L-myc fusion | -0.0247491 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.024203 |
| IER3 | immediate early response 3 | -0.0241049 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0236753 |
| PTMA | prothymosin, alpha | -0.0235898 |
| SULF1 | sulfatase 1 | -0.023583 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0230878 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0229913 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0213564 |
| KRT18 | keratin 18, type I | -0.0209429 |
| FAR1 | fatty acyl CoA reductase 1 | -0.0205447 |
| HLA-C | major histocompatibility complex, class I, C | -0.0205219 |
| FSTL1 | follistatin-like 1 | -0.0199092 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0198921 |
| HMGB2 | high mobility group box 2 | -0.0194837 |
| SUCO | SUN domain containing ossification factor | -0.0191732 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0189869 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0189722 |
| CAVIN1 | caveolae associated protein 1 | -0.0185872 |
| SERF2 | small EDRK-rich factor 2 | -0.0184695 |
| GNAS | GNAS complex locus | -0.0182856 |
| SNX4 | sorting nexin 4 | -0.0181411 |
| TPX2 | TPX2, microtubule-associated | -0.0180197 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) | -0.0180047 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0180031 |
| TMEM41B | transmembrane protein 41B | -0.0176477 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.0176 |
| ATP13A3 | ATPase type 13A3 | -0.0174814 |
| NAA50 | N(alpha)-acetyltransferase 50, NatE catalytic subunit | -0.0174468 |
| RBM25 | RNA binding motif protein 25 | -0.0173655 |
| SCFD2 | sec1 family domain containing 2 | -0.0171116 |
| H1-0 | H1.0 linker histone | -0.0170759 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0170488 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0169345 |
| UFM1 | ubiquitin-fold modifier 1 | -0.0168914 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0166913 |
| GOLT1B | golgi transport 1B | -0.0166319 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0166204 |
| RBM39 | RNA binding motif protein 39 | -0.0164317 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0164044 |
| HMGB1 | high mobility group box 1 | -0.0163963 |
| TM9SF2 | transmembrane 9 superfamily member 2 | -0.0162608 |
| AGFG1 | ArfGAP with FG repeats 1 | -0.0161676 |
| PABPN1 | poly(A) binding protein, nuclear 1 | -0.0160285 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.01593 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0159207 |
| THOC2 | THO complex 2 | -0.0158625 |
| RNF144B | ring finger protein 144B | -0.0157083 |
| RAB18 | RAB18, member RAS oncogene family | -0.0155573 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0155198 |
| MPZL1 | myelin protein zero-like 1 | -0.0154249 |
| KLF6 | Kruppel-like factor 6 | -0.0153859 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0153666 |
| BRIX1 | BRX1, biogenesis of ribosomes | -0.0151031 |
| ANLN | anillin, actin binding protein | -0.0150744 |
| NOP58 | NOP58 ribonucleoprotein | -0.0150111 |
| NUP153 | nucleoporin 153kDa | -0.0148278 |
| NPPB | natriuretic peptide B | -0.0147449 |
| RNF168 | ring finger protein 168, E3 ubiquitin protein ligase | -0.0146866 |
| GOLGA4 | golgin A4 | -0.014568 |
| RUNX2 | runt-related transcription factor 2 | -0.0144417 |
| OLR1 | oxidized low density lipoprotein (lectin-like) receptor 1 | -0.0143527 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0142834 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | -0.0142517 |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) | -0.0142511 |
| DENND4C | DENN/MADD domain containing 4C | -0.0142399 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0142231 |
| GLIS3 | GLIS family zinc finger 3 | -0.0141128 |
| TMEM178B | transmembrane protein 178B | -0.0140653 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | -0.0138326 |
| GOLGA2 | golgin A2 | -0.0138122 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | -0.013808 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0138023 |
| PFN1 | profilin 1 | -0.0137505 |
