| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | ULK-101 perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the ULK-101_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.135896 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.118707 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0613239 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0579897 |
| FAT1 | FAT atypical cadherin 1 | 0.0533414 |
| RPS6 | ribosomal protein S6 | 0.0469558 |
| EGFR | epidermal growth factor receptor | 0.0451205 |
| LMO7 | LIM domain 7 | 0.0434614 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0427015 |
| TPM4 | tropomyosin 4 | 0.0411712 |
| RPS8 | ribosomal protein S8 | 0.0366278 |
| NDRG1 | N-myc downstream regulated 1 | 0.0344596 |
| B2M | beta-2-microglobulin | 0.0342366 |
| ASPH | aspartate beta-hydroxylase | 0.033799 |
| MT2A | metallothionein 2A | 0.0335333 |
| RPL23 | ribosomal protein L23 | 0.0321358 |
| RPS19 | ribosomal protein S19 | 0.0305609 |
| RPLP1 | ribosomal protein, large, P1 | 0.0305495 |
| MYO1E | myosin IE | 0.0300817 |
| TXNIP | thioredoxin interacting protein | 0.028852 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0284449 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0271602 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0268921 |
| ENO1 | enolase 1, (alpha) | 0.0267811 |
| FTL | ferritin, light polypeptide | 0.0264151 |
| CALR | calreticulin | 0.025675 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0256725 |
| MED13 | mediator complex subunit 13 | 0.0253985 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0252585 |
| EXT1 | exostosin glycosyltransferase 1 | 0.025095 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0241536 |
| PCBP2 | poly(rC) binding protein 2 | 0.0239954 |
| RPL12 | ribosomal protein L12 | 0.0239807 |
| PKM | pyruvate kinase, muscle | 0.0235781 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | 0.0235425 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0233262 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0231384 |
| RPS23 | ribosomal protein S23 | 0.0228843 |
| RPS25 | ribosomal protein S25 | 0.0228088 |
| S100A10 | S100 calcium binding protein A10 | 0.0227434 |
| RPLP0 | ribosomal protein, large, P0 | 0.0224481 |
| SVIL | supervillin | 0.0224184 |
| RPS27 | ribosomal protein S27 | 0.0216982 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0216913 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0216419 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0214139 |
| RPS14 | ribosomal protein S14 | 0.021057 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | 0.0208494 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0208343 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0206154 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0204661 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0203214 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0200355 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0196215 |
| RPL7A | ribosomal protein L7a | 0.0196131 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.01951 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0193871 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0192149 |
| PTEN | phosphatase and tensin homolog | 0.0186527 |
| ACTG1 | actin gamma 1 | 0.0182205 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0180551 |
| FBXO11 | F-box protein 11 | 0.0179721 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | 0.0179235 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0176777 |
| LDHA | lactate dehydrogenase A | 0.0176108 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0175584 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0175483 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0174859 |
| EZR | ezrin | 0.0174541 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.017404 |
| RPS11 | ribosomal protein S11 | 0.0173419 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0173365 |
| RPS16 | ribosomal protein S16 | 0.0173174 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.017314 |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 | 0.0172978 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0172672 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0172648 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0171318 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0168168 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0167718 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0165869 |
| RPS13 | ribosomal protein S13 | 0.0165792 |
| ERBIN | erbb2 interacting protein | 0.0165337 |
| PGK1 | phosphoglycerate kinase 1 | 0.0165264 |
| RPL15 | ribosomal protein L15 | 0.0162011 |
| TGFBR3 | transforming growth factor, beta receptor III | 0.0161529 |
| S100A6 | S100 calcium binding protein A6 | 0.0161434 |
| S100A9 | S100 calcium binding protein A9 | 0.0160297 |
| RPL8 | ribosomal protein L8 | 0.0159987 |
| VMP1 | vacuole membrane protein 1 | 0.0159875 |
| AREG | amphiregulin | 0.015967 |
| VEGFA | vascular endothelial growth factor A | 0.0157955 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0156044 |
| SQSTM1 | sequestosome 1 | 0.0155742 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0150848 |
| RPS4X | ribosomal protein S4, X-linked | 0.0150603 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0149511 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0149465 |
| SIK3 | SIK family kinase 3 | 0.0148908 |
| RPL34 | ribosomal protein L34 | 0.0148266 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0611311 |
| GPHN | gephyrin | -0.0557504 |
| NPSR1 | neuropeptide S receptor 1 | -0.0522358 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0399383 |
| VCL | vinculin | -0.0381823 |
| PIGR | polymeric immunoglobulin receptor | -0.0357785 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0318386 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.031334 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0309628 |
| FLNB | filamin B, beta | -0.0306693 |
| NFIA | nuclear factor I/A | -0.0300632 |
| RNF43 | ring finger protein 43 | -0.028936 |
| EPCAM | epithelial cell adhesion molecule | -0.0284578 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0268091 |
| PCDHB16 | protocadherin beta 16 | -0.0260863 |
| RRBP1 | ribosome binding protein 1 | -0.0247602 |
| ANXA2 | annexin A2 | -0.024122 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0233031 |
| TFRC | transferrin receptor | -0.0232737 |
| GSK3B | glycogen synthase kinase 3 beta | -0.023141 |
| TNS4 | tensin 4 | -0.0229554 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0223722 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0223686 |
| ITGA6 | integrin, alpha 6 | -0.0218393 |
| RBM39 | RNA binding motif protein 39 | -0.0218124 |
| DERA | deoxyribose-phosphate aldolase (putative) | -0.0212928 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0210805 |
| WDR43 | WD repeat domain 43 | -0.0209213 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | -0.0207429 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0206348 |
| ETNK1 | ethanolamine kinase 1 | -0.0205696 |
| GDF15 | growth differentiation factor 15 | -0.0205258 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.020099 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | -0.0199438 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0198633 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.019775 |
| OGA | O-GlcNAcase | -0.019705 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0192966 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0192071 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0190945 |
| SHROOM3 | shroom family member 3 | -0.0184043 |
| ACTN4 | actinin, alpha 4 | -0.0181276 |
| HEPH | hephaestin | -0.0179767 |
| HDAC2 | histone deacetylase 2 | -0.0178085 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | -0.0176545 |
| PRSS3 | protease, serine, 3 | -0.0174779 |
| H1-0 | H1.0 linker histone | -0.0174652 |
| CTBP2 | C-terminal binding protein 2 | -0.0172838 |
| CAB39 | calcium binding protein 39 | -0.0172382 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0172066 |
| INSIG1 | insulin induced gene 1 | -0.0170366 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0169767 |
| SETD5 | SET domain containing 5 | -0.0168985 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | -0.0168811 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0161297 |
| ABHD17C | abhydrolase domain containing 17C | -0.0160703 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0159879 |
| MUC17 | mucin 17, cell surface associated | -0.0157664 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0155307 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | -0.0154917 |
| TMEM123 | transmembrane protein 123 | -0.0152905 |
| TKT | transketolase | -0.0151592 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0151006 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0150616 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.0150533 |
| PTPN4 | protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte) | -0.0149791 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0149503 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0149008 |
| LBR | lamin B receptor | -0.0145443 |
| EWSR1 | EWS RNA-binding protein 1 | -0.0145299 |
| MED13L | mediator complex subunit 13-like | -0.0144918 |
| PKP2 | plakophilin 2 | -0.0144837 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0143977 |
| IER3 | immediate early response 3 | -0.0142114 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.0140884 |
| FAM13A | family with sequence similarity 13, member A | -0.0140731 |
| NEMF | nuclear export mediator factor | -0.0139165 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0138655 |
| KIF5B | kinesin family member 5B | -0.0138063 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0136981 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0136506 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0136117 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0135998 |
| WWC1 | WW and C2 domain containing 1 | -0.0135437 |
| KIAA1217 | KIAA1217 | -0.0134751 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0134218 |
| GPA33 | glycoprotein A33 (transmembrane) | -0.0134186 |
| WDR45B | WD repeat domain 45B | -0.0133829 |
| PTMA | prothymosin, alpha | -0.0133782 |
| LIPG | lipase, endothelial | -0.0133622 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | -0.0133581 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0133307 |
| THOC2 | THO complex 2 | -0.0132736 |
| ETV6 | ets variant 6 | -0.0132648 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0132426 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0131062 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.0130928 |
| METTL15 | methyltransferase like 15 | -0.013026 |
| MECOM | MDS1 and EVI1 complex locus | -0.0130201 |
| CDK6 | cyclin-dependent kinase 6 | -0.0128838 |
