| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | ULK-101 perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the ULK-101_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CD44 | CD44 molecule (Indian blood group) | 0.146465 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.125415 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.114974 |
| GOLGA4 | golgin A4 | 0.107124 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.100256 |
| FNDC3B | fibronectin type III domain containing 3B | 0.100145 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0966518 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0825367 |
| PCBP2 | poly(rC) binding protein 2 | 0.0739625 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0708687 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0683082 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0680017 |
| NAV2 | neuron navigator 2 | 0.0666799 |
| USP34 | ubiquitin specific peptidase 34 | 0.0660983 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0645447 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.060543 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0602897 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0601724 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0594866 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.057305 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0572679 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0549857 |
| KYNU | kynureninase | 0.0541626 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0541267 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0517386 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0516612 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0509516 |
| GRB10 | growth factor receptor-bound protein 10 | 0.050379 |
| VIM | vimentin | 0.0501132 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0499725 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0494249 |
| SIK3 | SIK family kinase 3 | 0.0473939 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0470288 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0469029 |
| DSCAM | Down syndrome cell adhesion molecule | 0.046529 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0460458 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0456873 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0454278 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0432297 |
| RAP1B | RAP1B, member of RAS oncogene family | 0.0429517 |
| SMAD3 | SMAD family member 3 | 0.041327 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0405163 |
| CANX | calnexin | 0.0401819 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0400527 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0399751 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0388248 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0387003 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0382486 |
| FNIP1 | folliculin interacting protein 1 | 0.0382077 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0379791 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0376549 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0375414 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0374697 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.0371167 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0364255 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0359663 |
| HDLBP | high density lipoprotein binding protein | 0.0355501 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0354683 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | 0.0351408 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0350149 |
| JMJD1C | jumonji domain containing 1C | 0.0349408 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0348839 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0347931 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.034393 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0342741 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.034039 |
| CA12 | carbonic anhydrase XII | 0.0339835 |
| OS9 | osteosarcoma amplified 9, endoplasmic reticulum lectin | 0.0338586 |
| SLC41A2 | solute carrier family 41 (magnesium transporter), member 2 | 0.0329995 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0329707 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.032827 |
| SYAP1 | synapse associated protein 1 | 0.0325834 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0325515 |
| HAS2 | hyaluronan synthase 2 | 0.0325284 |
| COPA | coatomer protein complex, subunit alpha | 0.0322246 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0320907 |
| OSMR | oncostatin M receptor | 0.0319422 |
| ITGAV | integrin, alpha V | 0.0318744 |
| CALU | calumenin | 0.0318605 |
| SFTPA2 | surfactant protein A2 | 0.0316692 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.031609 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0315599 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0314207 |
| ATP13A3 | ATPase type 13A3 | 0.0313639 |
| YME1L1 | YME1-like 1 ATPase | 0.0312424 |
| SPAG9 | sperm associated antigen 9 | 0.0309196 |
| EGFR | epidermal growth factor receptor | 0.0308669 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0308419 |
| SEC24A | SEC24 family member A | 0.030466 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0303704 |
| VMP1 | vacuole membrane protein 1 | 0.0301781 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0297948 |
| LMAN1 | lectin, mannose-binding, 1 | 0.0296751 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0296194 |
| LOX | lysyl oxidase | 0.0295005 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0294103 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0292106 |
| FAM13A | family with sequence similarity 13, member A | 0.0291738 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0288007 |
| SQSTM1 | sequestosome 1 | 0.0287275 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.105 |
| FN1 | fibronectin 1 | -0.0830205 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0521181 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0494695 |
| FTL | ferritin, light polypeptide | -0.0473174 |
| RPL35A | ribosomal protein L35a | -0.0464302 |
| HMGA2 | high mobility group AT-hook 2 | -0.0342106 |
| CDH13 | cadherin 13 | -0.0329507 |
| GLCCI1 | glucocorticoid induced 1 | -0.0325707 |
| ZNF804A | zinc finger protein 804A | -0.0307649 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0304871 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0290799 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0283422 |
| RPL31 | ribosomal protein L31 | -0.0280709 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0273632 |
| COL7A1 | collagen, type VII, alpha 1 | -0.0271154 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.024856 |
| MECOM | MDS1 and EVI1 complex locus | -0.0243686 |
| RPL37A | ribosomal protein L37a | -0.024316 |
| NTN4 | netrin 4 | -0.0239891 |
| ATG7 | autophagy related 7 | -0.0233639 |
| PTMA | prothymosin, alpha | -0.0224362 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0222038 |
| RPL28 | ribosomal protein L28 | -0.0221781 |
| MT2A | metallothionein 2A | -0.0219435 |
| RPL36 | ribosomal protein L36 | -0.021559 |
| RPS21 | ribosomal protein S21 | -0.0214868 |
| RPS19 | ribosomal protein S19 | -0.0206941 |
| NAV3 | neuron navigator 3 | -0.0206526 |
| RPS29 | ribosomal protein S29 | -0.0202071 |
| RPL19 | ribosomal protein L19 | -0.0200794 |
| HDAC4 | histone deacetylase 4 | -0.0197169 |
| NRG1 | neuregulin 1 | -0.0196189 |
| COL12A1 | collagen, type XII, alpha 1 | -0.0189483 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0188819 |
| VRK2 | vaccinia related kinase 2 | -0.0186348 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.0186085 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0185438 |
| GLIS3 | GLIS family zinc finger 3 | -0.0183277 |
| GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 | -0.0181142 |
| EFCAB13 | EF-hand calcium binding domain 13 | -0.0180352 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0179594 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0179315 |
| RPL38 | ribosomal protein L38 | -0.0178503 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0176257 |
| INTS6 | integrator complex subunit 6 | -0.0175622 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0173975 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0172676 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0171195 |
| RPS23 | ribosomal protein S23 | -0.0170934 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0168163 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | -0.016504 |
| ZBTB7A | zinc finger and BTB domain containing 7A | -0.016157 |
| RPLP2 | ribosomal protein, large, P2 | -0.0161049 |
| RPL11 | ribosomal protein L11 | -0.0159446 |
| COX4I1 | cytochrome c oxidase subunit IV isoform 1 | -0.0158442 |
| RPS25 | ribosomal protein S25 | -0.015593 |
| ABCA9 | ATP-binding cassette, sub-family A (ABC1), member 9 | -0.0154689 |
| PRRX1 | paired related homeobox 1 | -0.0152156 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0150523 |
| PRELID2 | PRELI domain containing 2 | -0.0149719 |
| SEC61G | Sec61 gamma subunit | -0.0148627 |
| PFN1 | profilin 1 | -0.0146234 |
| ABCA6 | ATP-binding cassette, sub-family A (ABC1), member 6 | -0.0145866 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0145687 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0140909 |
| HTR1F | 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled | -0.0140525 |
| PDE7B | phosphodiesterase 7B | -0.0139441 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0139162 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.0138998 |
| ACTN1 | actinin, alpha 1 | -0.013862 |
| QSOX1 | quiescin Q6 sulfhydryl oxidase 1 | -0.0138475 |
| RPS13 | ribosomal protein S13 | -0.013831 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.013561 |
| TBL1X | transducin (beta)-like 1X-linked | -0.0134518 |
| ANXA10 | annexin A10 | -0.0133461 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.013314 |
| SYT1 | synaptotagmin I | -0.0132084 |
| SERF2 | small EDRK-rich factor 2 | -0.0130164 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0129511 |
| GNAS | GNAS complex locus | -0.0128773 |
| SLC43A3 | solute carrier family 43, member 3 | -0.0128606 |
| RPL9 | ribosomal protein L9 | -0.0126323 |
| KLF12 | Kruppel-like factor 12 | -0.0125038 |
| CP | ceruloplasmin (ferroxidase) | -0.012495 |
| COL4A5 | collagen, type IV, alpha 5 | -0.0123972 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.012373 |
| RPS27A | ribosomal protein S27a | -0.012246 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0121979 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0120295 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.0120256 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.0119427 |
| NLK | nemo-like kinase | -0.0117951 |
| IFI44 | interferon-induced protein 44 | -0.0117145 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | -0.0117144 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 | -0.0113024 |
| POTEF | POTE ankyrin domain family, member F | -0.0111707 |
| CDKL1 | cyclin-dependent kinase-like 1 (CDC2-related kinase) | -0.0111615 |
| SERPINB6 | serpin peptidase inhibitor, clade B (ovalbumin), member 6 | -0.0111223 |
| RPS10 | ribosomal protein S10 | -0.0111009 |
