| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | ULK-101 perturbation in PANC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the ULK-101_PANC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FNDC3B | fibronectin type III domain containing 3B | 0.0405195 |
| NAV2 | neuron navigator 2 | 0.0324032 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0311178 |
| JMJD1C | jumonji domain containing 1C | 0.0272569 |
| SFTPA2 | surfactant protein A2 | 0.0269023 |
| HDAC9 | histone deacetylase 9 | 0.0250525 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0246434 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0233902 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0200848 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0200558 |
| RPLP0 | ribosomal protein, large, P0 | 0.0191628 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0154145 |
| RPS2 | ribosomal protein S2 | 0.0152196 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0151231 |
| AGO3 | argonaute RISC catalytic component 3 | 0.0150187 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0148734 |
| SQSTM1 | sequestosome 1 | 0.0141756 |
| ZFP36 | ZFP36 ring finger protein | 0.0140166 |
| KLHL24 | kelch-like family member 24 | 0.0139962 |
| EGFR | epidermal growth factor receptor | 0.0135061 |
| LRRC49 | leucine rich repeat containing 49 | 0.0134755 |
| BMP6 | bone morphogenetic protein 6 | 0.013352 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0133473 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0133132 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0132245 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0124032 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0119864 |
| CREBRF | CREB3 regulatory factor | 0.0119816 |
| VMP1 | vacuole membrane protein 1 | 0.01195 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0117345 |
| MYOF | myoferlin | 0.0113413 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0111874 |
| TFDP2 | transcription factor Dp-2 (E2F dimerization partner 2) | 0.0110354 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0109859 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0108584 |
| MATR3 | matrin 3 | 0.0107644 |
| FMNL2 | formin-like 2 | 0.0106777 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | 0.0104356 |
| RPL21 | ribosomal protein L21 | 0.0102963 |
| RPS18 | ribosomal protein S18 | 0.0101788 |
| FNIP1 | folliculin interacting protein 1 | 0.0101229 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0101143 |
| SPIRE1 | spire-type actin nucleation factor 1 | 0.0100742 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | 0.0100468 |
| UBAP2 | ubiquitin associated protein 2 | 0.0100297 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.00962019 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.00942731 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.00937154 |
| SERINC1 | serine incorporator 1 | 0.00930244 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.00928109 |
| TAF4B | TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa | 0.00926556 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.00923427 |
| RSF1 | remodeling and spacing factor 1 | 0.00919346 |
| ASTN2 | astrotactin 2 | 0.00914208 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.009088 |
| VPS13C | vacuolar protein sorting 13 homolog C (S. cerevisiae) | 0.00908039 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 0.00894666 |
| GADD45B | growth arrest and DNA-damage-inducible, beta | 0.00892395 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.00890706 |
| FOSL1 | FOS-like antigen 1 | 0.00881653 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0087157 |
| YAP1 | Yes-associated protein 1 | 0.0086875 |
| DDIT3 | DNA-damage-inducible transcript 3 | 0.0085469 |
| GSPT1 | G1 to S phase transition 1 | 0.00836484 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.00832088 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.00821086 |
| ERBIN | erbb2 interacting protein | 0.00819714 |
| HOMER1 | homer scaffolding protein 1 | 0.00804585 |
| RPL39 | ribosomal protein L39 | 0.0080405 |
| ATF6 | activating transcription factor 6 | 0.00792992 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.00779052 |
| EGR1 | early growth response 1 | 0.00769165 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.00765467 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | 0.00760744 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.00757767 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.00755304 |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | 0.00750787 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.00743647 |
| PHF21A | PHD finger protein 21A | 0.00736217 |
| STAG2 | stromal antigen 2 | 0.00734889 |
| NUP58 | nucleoporin 58 | 0.0073478 |
| PUM1 | pumilio RNA-binding family member 1 | 0.007312 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.00728499 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | 0.00724258 |
| MSN | moesin | 0.00723104 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.00723101 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.00719113 |
| INO80 | INO80 complex subunit | 0.00714805 |
| C6ORF62 | chromosome 6 open reading frame 62 | 0.00714574 |
| UBE2R2 | ubiquitin-conjugating enzyme E2R 2 | 0.00713415 |
| MAP2K5 | mitogen-activated protein kinase kinase 5 | 0.00703822 |
| HBP1 | HMG-box transcription factor 1 | 0.00701486 |
| ZBTB10 | zinc finger and BTB domain containing 10 | 0.00698612 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.00698232 |
| UBXN7 | UBX domain protein 7 | 0.00697453 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.00695429 |
| ATP11B | ATPase, class VI, type 11B | 0.00691567 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0068925 |
| MYO9A | myosin IXA | 0.00685685 |
| KIF1B | kinesin family member 1B | 0.00683674 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.167064 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.147654 |
| PTMA | prothymosin, alpha | -0.143658 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.11216 |
| ACTN4 | actinin, alpha 4 | -0.11166 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.102072 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.085126 |
| TMSB10 | thymosin beta 10 | -0.0824663 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | -0.0785017 |
| UBC | ubiquitin C | -0.0765531 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0744305 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0732938 |
| AHNAK | AHNAK nucleoprotein | -0.0700213 |
| RPS16 | ribosomal protein S16 | -0.053574 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0518784 |
| RPS27A | ribosomal protein S27a | -0.0514941 |
| ENO1 | enolase 1, (alpha) | -0.0513754 |
| ANXA2 | annexin A2 | -0.0465779 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0439955 |
| LDHA | lactate dehydrogenase A | -0.0417481 |
| CD44 | CD44 molecule (Indian blood group) | -0.0406974 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0399148 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0382523 |
| CANX | calnexin | -0.0378054 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0373013 |
| RTN4 | reticulon 4 | -0.0363208 |
| CALR | calreticulin | -0.0340171 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | -0.0336531 |
| RPLP2 | ribosomal protein, large, P2 | -0.0336271 |
| PSMC4 | proteasome (prosome, macropain) 26S subunit, ATPase, 4 | -0.0327191 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0318787 |
| VCL | vinculin | -0.0316377 |
| RPL37A | ribosomal protein L37a | -0.0311223 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0311076 |
| FTL | ferritin, light polypeptide | -0.030761 |
| PGK1 | phosphoglycerate kinase 1 | -0.0304828 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0303944 |
| LMNA | lamin A/C | -0.0299878 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0295576 |
| RPL35A | ribosomal protein L35a | -0.0294887 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0294421 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0284669 |
| ANLN | anillin, actin binding protein | -0.028244 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0277969 |
| ACTG1 | actin gamma 1 | -0.0272167 |
| RPS3 | ribosomal protein S3 | -0.0271776 |
| CARD18 | caspase recruitment domain family, member 18 | -0.026919 |
| TMEM123 | transmembrane protein 123 | -0.0249112 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0246218 |
| MKI67 | marker of proliferation Ki-67 | -0.0239071 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0238977 |
| DSTN | destrin (actin depolymerizing factor) | -0.0238599 |
| S100A6 | S100 calcium binding protein A6 | -0.0233537 |
| CAVIN1 | caveolae associated protein 1 | -0.0230058 |
| ASPH | aspartate beta-hydroxylase | -0.0229476 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0229015 |
| DRAP1 | DR1-associated protein 1 (negative cofactor 2 alpha) | -0.022857 |
| AFAP1 | actin filament associated protein 1 | -0.022689 |
| PAF1 | Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) | -0.0222518 |
| RPS24 | ribosomal protein S24 | -0.0222201 |
| APP | amyloid beta (A4) precursor protein | -0.0219443 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0218872 |
| MAP1B | microtubule-associated protein 1B | -0.0218624 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0217834 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0215633 |
| RPL38 | ribosomal protein L38 | -0.0209196 |
| GNAS | GNAS complex locus | -0.0205121 |
| FBL | fibrillarin | -0.0200748 |
| EIF3K | eukaryotic translation initiation factor 3, subunit K | -0.0198542 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0196983 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0196448 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0196219 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.019532 |
| RPS25 | ribosomal protein S25 | -0.0194567 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.019372 |
| OGA | O-GlcNAcase | -0.0192228 |
| FBXO17 | F-box protein 17 | -0.0191767 |
| HNRNPL | heterogeneous nuclear ribonucleoprotein L | -0.0188111 |
| CTTN | cortactin | -0.0188045 |
| SEPTIN7 | septin 7 | -0.018419 |
| PKM | pyruvate kinase, muscle | -0.0183332 |
| AKT2 | v-akt murine thymoma viral oncogene homolog 2 | -0.0183294 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0182448 |
| RPL31 | ribosomal protein L31 | -0.0180605 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0180161 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0178279 |
| THOC2 | THO complex 2 | -0.0177577 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.0177512 |
| PFN1 | profilin 1 | -0.0177386 |
| SEPTIN9 | septin 9 | -0.0176449 |
| H1-0 | H1.0 linker histone | -0.017491 |
| MAP4 | microtubule-associated protein 4 | -0.01737 |
| FHL2 | four and a half LIM domains 2 | -0.0173371 |
| ERGIC1 | endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 | -0.0172872 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0172517 |
| COL18A1 | collagen, type XVIII, alpha 1 | -0.0172434 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 | -0.0170412 |
| RPL19 | ribosomal protein L19 | -0.0167073 |
| ZNF780B | zinc finger protein 780B | -0.016615 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | -0.0164753 |
