| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | ULK-101 perturbation in Panc 03.27 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the ULK-101_Panc 03.27 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.137717 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.114736 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.111445 |
| LMO7 | LIM domain 7 | 0.102415 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.10016 |
| SQSTM1 | sequestosome 1 | 0.0875226 |
| SVIL | supervillin | 0.0864482 |
| ACTG1 | actin gamma 1 | 0.0798021 |
| RPS8 | ribosomal protein S8 | 0.0743297 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0714754 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0699159 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0696823 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0692314 |
| TPM4 | tropomyosin 4 | 0.0662209 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0652443 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0636867 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0598681 |
| CD44 | CD44 molecule (Indian blood group) | 0.05919 |
| MYO5B | myosin VB | 0.0585988 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.057943 |
| MYO6 | myosin VI | 0.0571834 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0567633 |
| RACK1 | receptor for activated C kinase 1 | 0.0562203 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | 0.056097 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0558404 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0552203 |
| HMGA1 | high mobility group AT-hook 1 | 0.0547126 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0540637 |
| RPS12 | ribosomal protein S12 | 0.0537776 |
| INTS6 | integrator complex subunit 6 | 0.0519904 |
| FN1 | fibronectin 1 | 0.0512057 |
| EGFR | epidermal growth factor receptor | 0.0506127 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0497797 |
| NAV2 | neuron navigator 2 | 0.0494575 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0492703 |
| ADAMTS9 | ADAM metallopeptidase with thrombospondin type 1 motif, 9 | 0.0488886 |
| HDAC9 | histone deacetylase 9 | 0.0485875 |
| RPL23 | ribosomal protein L23 | 0.0469316 |
| DSPP | dentin sialophosphoprotein | 0.0468256 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | 0.0457852 |
| PCBP2 | poly(rC) binding protein 2 | 0.0452376 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0448613 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0444619 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0441445 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0437694 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0434029 |
| POTEF | POTE ankyrin domain family, member F | 0.0429945 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0425654 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0424656 |
| RPS6 | ribosomal protein S6 | 0.0422563 |
| SNX9 | sorting nexin 9 | 0.0415284 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0415173 |
| SYT14 | synaptotagmin XIV | 0.0413556 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0403248 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0401998 |
| TJP1 | tight junction protein 1 | 0.0397925 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | 0.03972 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0393473 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0391406 |
| TXNIP | thioredoxin interacting protein | 0.0386539 |
| RPS3 | ribosomal protein S3 | 0.0383161 |
| HMGA2 | high mobility group AT-hook 2 | 0.037752 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | 0.0375798 |
| LAMC2 | laminin, gamma 2 | 0.0370103 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0364747 |
| FMNL2 | formin-like 2 | 0.0364132 |
| RPS13 | ribosomal protein S13 | 0.0363578 |
| MYO1E | myosin IE | 0.0362262 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0357274 |
| FAM107B | family with sequence similarity 107, member B | 0.0356016 |
| DOCK9 | dedicator of cytokinesis 9 | 0.0353094 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0352537 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0348365 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0347851 |
| RPS17 | ribosomal protein S17 | 0.0347618 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0344644 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0341044 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0335061 |
| CANX | calnexin | 0.0335016 |
| RPS19 | ribosomal protein S19 | 0.0329228 |
| KLF6 | Kruppel-like factor 6 | 0.0326563 |
| SMAD3 | SMAD family member 3 | 0.032563 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0324178 |
| CD59 | CD59 molecule, complement regulatory protein | 0.032338 |
| RPL12 | ribosomal protein L12 | 0.0323064 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0319371 |
| RPL18 | ribosomal protein L18 | 0.031918 |
| ERBIN | erbb2 interacting protein | 0.0316096 |
| AHNAK | AHNAK nucleoprotein | 0.0309435 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0308346 |
| LAMB3 | laminin, beta 3 | 0.030453 |
| RPL10A | ribosomal protein L10a | 0.0303614 |
| ENO1 | enolase 1, (alpha) | 0.0302444 |
| KRT7 | keratin 7, type II | 0.0302287 |
| SOX4 | SRY (sex determining region Y)-box 4 | 0.0302169 |
| FNIP1 | folliculin interacting protein 1 | 0.0301791 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0301608 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | 0.0300011 |
| PSEN1 | presenilin 1 | 0.0299853 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0299441 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.142516 |
| MUC4 | mucin 4, cell surface associated | -0.116851 |
| PTMA | prothymosin, alpha | -0.108476 |
| LAMA4 | laminin, alpha 4 | -0.0754435 |
| MKI67 | marker of proliferation Ki-67 | -0.0614347 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0591364 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0570085 |
| ANLN | anillin, actin binding protein | -0.0563789 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0559105 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0549057 |
| DIAPH3 | diaphanous-related formin 3 | -0.0527983 |
| PLAT | plasminogen activator, tissue | -0.0524545 |
| HLA-B | major histocompatibility complex, class I, B | -0.0513983 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0510966 |
| IL1RAP | interleukin 1 receptor accessory protein | -0.0477057 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.0449873 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0448152 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0445401 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0436496 |
| VCL | vinculin | -0.0425063 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0420942 |
| OSBPL3 | oxysterol binding protein-like 3 | -0.0418618 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0403074 |
| KRT17 | keratin 17, type I | -0.0393195 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0392524 |
| ECT2 | epithelial cell transforming 2 | -0.0386137 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0378225 |
| HLA-C | major histocompatibility complex, class I, C | -0.0375673 |
| GOLGA4 | golgin A4 | -0.0363248 |
| CCNL1 | cyclin L1 | -0.0342577 |
| WWC1 | WW and C2 domain containing 1 | -0.0340698 |
| THBS1 | thrombospondin 1 | -0.0340176 |
| OSMR | oncostatin M receptor | -0.0338552 |
| CD2AP | CD2-associated protein | -0.0334695 |
| TGM2 | transglutaminase 2 | -0.0333124 |
| OGA | O-GlcNAcase | -0.0325732 |
| TRA2B | transformer 2 beta homolog (Drosophila) | -0.0323436 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.032174 |
| NFIB | nuclear factor I/B | -0.0315974 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.030885 |
| STK24 | serine/threonine kinase 24 | -0.0303209 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0288808 |
| RBM39 | RNA binding motif protein 39 | -0.0285639 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0284474 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0279144 |
| EFNA5 | ephrin-A5 | -0.0277756 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0269766 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.0262974 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0256439 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0256184 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0255429 |
| NF1 | neurofibromin 1 | -0.0255089 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0251782 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0250882 |
| SHROOM3 | shroom family member 3 | -0.0250405 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0247243 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0243074 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | -0.0241797 |
| LDHA | lactate dehydrogenase A | -0.0240604 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0238835 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | -0.0234727 |
| EHF | ets homologous factor | -0.023381 |
| RBM25 | RNA binding motif protein 25 | -0.0233291 |
| H3-3B | H3.3 histone B | -0.0231966 |
| CENPF | centromere protein F, 350/400kDa | -0.0230845 |
| RTN4 | reticulon 4 | -0.0229151 |
| TXNRD1 | thioredoxin reductase 1 | -0.0228146 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0222469 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0221935 |
| H1-0 | H1.0 linker histone | -0.0221748 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | -0.0218716 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0218651 |
| FCHSD2 | FCH and double SH3 domains 2 | -0.0218355 |
| TOP1 | topoisomerase (DNA) I | -0.0216943 |
| TMEM123 | transmembrane protein 123 | -0.021491 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0213181 |
| C3 | complement component 3 | -0.021074 |
| RPL35A | ribosomal protein L35a | -0.0210528 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0206422 |
| TMSB10 | thymosin beta 10 | -0.0205181 |
| EGR1 | early growth response 1 | -0.0204248 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0203602 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0202992 |
| SETD5 | SET domain containing 5 | -0.0197326 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0192563 |
| SPAG9 | sperm associated antigen 9 | -0.0185145 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | -0.0184963 |
| CENPE | centromere protein E, 312kDa | -0.0183045 |
| BCL2L1 | BCL2-like 1 | -0.0182692 |
| WDR45B | WD repeat domain 45B | -0.0182628 |
| RLF | rearranged L-myc fusion | -0.0182244 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0181927 |
| SUCO | SUN domain containing ossification factor | -0.0181421 |
| CDC27 | cell division cycle 27 | -0.0181098 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0179021 |
| ITGAV | integrin, alpha V | -0.0178214 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.017788 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | -0.0176327 |
| MAPK8 | mitogen-activated protein kinase 8 | -0.0175948 |
| CMTM7 | CKLF-like MARVEL transmembrane domain containing 7 | -0.0174032 |
