| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | ULK-101 perturbation in RPMI-7951 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the ULK-101_RPMI-7951 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| STC1 | stanniocalcin 1 | 0.157644 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0805772 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0693321 |
| HDAC9 | histone deacetylase 9 | 0.054795 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0530755 |
| FNIP1 | folliculin interacting protein 1 | 0.0523941 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0516292 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0515978 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.048821 |
| B2M | beta-2-microglobulin | 0.0470433 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0440249 |
| NAV2 | neuron navigator 2 | 0.043192 |
| EGR1 | early growth response 1 | 0.0429576 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0421225 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0405942 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0400211 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0398861 |
| SQSTM1 | sequestosome 1 | 0.0390308 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0387072 |
| RND3 | Rho family GTPase 3 | 0.0380584 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0369011 |
| EML5 | echinoderm microtubule associated protein like 5 | 0.0362393 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0355275 |
| HMGA2 | high mobility group AT-hook 2 | 0.0318484 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0302423 |
| MMP12 | matrix metallopeptidase 12 | 0.0298157 |
| SMAD3 | SMAD family member 3 | 0.0297877 |
| STK10 | serine/threonine kinase 10 | 0.0296721 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0289416 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0284949 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0280424 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0278832 |
| CADM1 | cell adhesion molecule 1 | 0.0278347 |
| LYST | lysosomal trafficking regulator | 0.0274875 |
| VPS13C | vacuolar protein sorting 13 homolog C (S. cerevisiae) | 0.0269447 |
| AGPAT5 | 1-acylglycerol-3-phosphate O-acyltransferase 5 | 0.0268741 |
| HPCAL1 | hippocalcin-like 1 | 0.0268628 |
| HLA-E | major histocompatibility complex, class I, E | 0.0266316 |
| MYO9A | myosin IXA | 0.0263952 |
| EXOC4 | exocyst complex component 4 | 0.0258076 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0253173 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0252127 |
| TMEM132D | transmembrane protein 132D | 0.0251302 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.025051 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0249178 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | 0.0246164 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | 0.0245574 |
| MCL1 | myeloid cell leukemia 1 | 0.0243962 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0243532 |
| COL4A1 | collagen, type IV, alpha 1 | 0.0239482 |
| FAT1 | FAT atypical cadherin 1 | 0.0238265 |
| PLSCR1 | phospholipid scramblase 1 | 0.0237184 |
| RPS8 | ribosomal protein S8 | 0.0234691 |
| FMNL2 | formin-like 2 | 0.0232154 |
| IL1B | interleukin 1, beta | 0.0227876 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0226947 |
| JUN | jun proto-oncogene | 0.0224717 |
| BPTF | bromodomain PHD finger transcription factor | 0.0222515 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0221781 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0221004 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0220236 |
| FHIT | fragile histidine triad | 0.0216448 |
| SP100 | SP100 nuclear antigen | 0.0210448 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0208315 |
| RAI14 | retinoic acid induced 14 | 0.0207511 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0207096 |
| RPS4X | ribosomal protein S4, X-linked | 0.0205965 |
| RPLP1 | ribosomal protein, large, P1 | 0.0205838 |
| SFTPA2 | surfactant protein A2 | 0.0205501 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0204917 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0204223 |
| ARL4C | ADP-ribosylation factor-like 4C | 0.020413 |
| PLIN2 | perilipin 2 | 0.0203312 |
| GOLGB1 | golgin B1 | 0.0199548 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.019937 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.019928 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.01968 |
| RPL23 | ribosomal protein L23 | 0.0196759 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.019614 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0194206 |
| RPS17 | ribosomal protein S17 | 0.0193656 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.0192486 |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | 0.0190783 |
| PARD3 | par-3 family cell polarity regulator | 0.0189727 |
| CTSL | cathepsin L | 0.0189071 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0187984 |
| AGO3 | argonaute RISC catalytic component 3 | 0.0186164 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0185534 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0185528 |
| NBEAL1 | neurobeachin-like 1 | 0.0183421 |
| WDPCP | WD repeat containing planar cell polarity effector | 0.0181936 |
| HLA-A | major histocompatibility complex, class I, A | 0.0180215 |
| ANXA2 | annexin A2 | 0.0179755 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0179491 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0176208 |
| LRRC23 | leucine rich repeat containing 23 | 0.0175539 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.017547 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0172417 |
| MMP2 | matrix metallopeptidase 2 | 0.0172195 |
| SVIL | supervillin | 0.0170716 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.356893 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.12099 |
| NDRG1 | N-myc downstream regulated 1 | -0.096098 |
| COL1A1 | collagen, type I, alpha 1 | -0.0893287 |
| COL1A2 | collagen, type I, alpha 2 | -0.0859423 |
| VIM | vimentin | -0.0625642 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0623098 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0571997 |
| POTEF | POTE ankyrin domain family, member F | -0.0554691 |
| FRMD4A | FERM domain containing 4A | -0.0552764 |
| TMSB10 | thymosin beta 10 | -0.0531516 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0523133 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0522606 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.050247 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0431418 |
| PTMA | prothymosin, alpha | -0.0429585 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0427328 |
| SETD5 | SET domain containing 5 | -0.0415829 |
| PGK1 | phosphoglycerate kinase 1 | -0.0396677 |
| CALD1 | caldesmon 1 | -0.0392538 |
| MSN | moesin | -0.0388567 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0381932 |
| RTN4 | reticulon 4 | -0.0369756 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0369586 |
| COL5A1 | collagen, type V, alpha 1 | -0.0355571 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0348576 |
| RBM39 | RNA binding motif protein 39 | -0.0343161 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0338871 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0332676 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0330187 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.0323947 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0320911 |
| TNNC1 | troponin C type 1 (slow) | -0.0316215 |
| PKM | pyruvate kinase, muscle | -0.0316182 |
| NRP1 | neuropilin 1 | -0.0315573 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.031128 |
| VEGFA | vascular endothelial growth factor A | -0.0308706 |
| MEF2A | myocyte enhancer factor 2A | -0.0300688 |
| TPM1 | tropomyosin 1 (alpha) | -0.0294418 |
| ANLN | anillin, actin binding protein | -0.0291928 |
| TMEM178B | transmembrane protein 178B | -0.0288028 |
| ZNF292 | zinc finger protein 292 | -0.0287238 |
| SEPTIN7 | septin 7 | -0.0284896 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0283331 |
| IFI44 | interferon-induced protein 44 | -0.0279325 |
| RNF24 | ring finger protein 24 | -0.0278943 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0277099 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.027607 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.0275671 |
| CAPZB | capping protein (actin filament) muscle Z-line, beta | -0.0273093 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | -0.0272791 |
| FLNB | filamin B, beta | -0.0263279 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0261387 |
| MKI67 | marker of proliferation Ki-67 | -0.0261206 |
| GNAS | GNAS complex locus | -0.0259351 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0259059 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0258815 |
| CENPF | centromere protein F, 350/400kDa | -0.0254723 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0252843 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0252197 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0249025 |
| PLOD1 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 | -0.0247474 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0244807 |
| NBAS | neuroblastoma amplified sequence | -0.0244741 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0243912 |
| CCNL1 | cyclin L1 | -0.0242406 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0242 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0241875 |
| YEATS2 | YEATS domain containing 2 | -0.0237269 |
| DSTN | destrin (actin depolymerizing factor) | -0.0236175 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0235429 |
| ZNF148 | zinc finger protein 148 | -0.0234675 |
| PFN1 | profilin 1 | -0.0231089 |
| XPO1 | exportin 1 | -0.022944 |
| HLA-B | major histocompatibility complex, class I, B | -0.0225321 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0223899 |
| SPAG9 | sperm associated antigen 9 | -0.0223763 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0223091 |
| BBX | bobby sox homolog (Drosophila) | -0.0222374 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0221853 |
| TMEM39A | transmembrane protein 39A | -0.0221724 |
| MAP4 | microtubule-associated protein 4 | -0.0220262 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0220081 |
| FAM162A | family with sequence similarity 162, member A | -0.0219909 |
| NKTR | natural killer cell triggering receptor | -0.0218246 |
| DIAPH3 | diaphanous-related formin 3 | -0.021196 |
| TPX2 | TPX2, microtubule-associated | -0.0211766 |
| THBS1 | thrombospondin 1 | -0.020949 |
| ASPH | aspartate beta-hydroxylase | -0.0208408 |
| NUP58 | nucleoporin 58 | -0.0207131 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.020543 |
| LDHA | lactate dehydrogenase A | -0.0205188 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0204973 |
| AFAP1 | actin filament associated protein 1 | -0.0203486 |
| ITGA1 | integrin, alpha 1 | -0.0203437 |
| TFG | TRK-fused gene | -0.01984 |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) | -0.0197845 |
| RFX7 | regulatory factor X, 7 | -0.0197808 |
| PDE10A | phosphodiesterase 10A | -0.0197269 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | -0.0196821 |
