| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | ULK-101 perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the ULK-101_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0993494 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0884678 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0849296 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0722551 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0686762 |
| ZNF292 | zinc finger protein 292 | 0.0617452 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0558341 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0557301 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0542354 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0535107 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0491822 |
| EZR | ezrin | 0.0491693 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.047963 |
| PTMA | prothymosin, alpha | 0.047524 |
| GOLGA4 | golgin A4 | 0.0475133 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0465011 |
| EML4 | echinoderm microtubule associated protein like 4 | 0.0452098 |
| TXNRD1 | thioredoxin reductase 1 | 0.0447614 |
| RBM39 | RNA binding motif protein 39 | 0.0436345 |
| QKI | QKI, KH domain containing, RNA binding | 0.0428739 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0425568 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0420703 |
| RTN4 | reticulon 4 | 0.0409152 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0407547 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.039751 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0394774 |
| B2M | beta-2-microglobulin | 0.038099 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0379994 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0372557 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.036708 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0362494 |
| JMJD1C | jumonji domain containing 1C | 0.0353174 |
| RNF145 | ring finger protein 145 | 0.0352165 |
| MATR3 | matrin 3 | 0.034348 |
| FLNB | filamin B, beta | 0.0335318 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0327274 |
| TXNIP | thioredoxin interacting protein | 0.0324036 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0319383 |
| CNOT6L | CCR4-NOT transcription complex, subunit 6-like | 0.0316127 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0313669 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | 0.0309953 |
| CCNL1 | cyclin L1 | 0.0309073 |
| S100A6 | S100 calcium binding protein A6 | 0.0304357 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0301498 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0300479 |
| NUP58 | nucleoporin 58 | 0.0291591 |
| RBM25 | RNA binding motif protein 25 | 0.0289171 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0288043 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0287035 |
| VMP1 | vacuole membrane protein 1 | 0.0284452 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0279771 |
| PGK1 | phosphoglycerate kinase 1 | 0.0277697 |
| CDC73 | cell division cycle 73 | 0.0277284 |
| USP3 | ubiquitin specific peptidase 3 | 0.0276838 |
| RHOA | ras homolog family member A | 0.0271607 |
| TMEM41B | transmembrane protein 41B | 0.0268611 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0265679 |
| RLF | rearranged L-myc fusion | 0.0263978 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.026225 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0260702 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0258997 |
| HDAC9 | histone deacetylase 9 | 0.0254757 |
| ZNF608 | zinc finger protein 608 | 0.025455 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0253321 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0252855 |
| TFG | TRK-fused gene | 0.0250754 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0249856 |
| CRY1 | cryptochrome circadian clock 1 | 0.0249509 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0243815 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0243741 |
| FBXO11 | F-box protein 11 | 0.0242011 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.0239593 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0236653 |
| ATOSA | atos homolog A | 0.0234028 |
| NCKAP1 | NCK-associated protein 1 | 0.0233651 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0233356 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0231083 |
| ECT2 | epithelial cell transforming 2 | 0.0229832 |
| WDR43 | WD repeat domain 43 | 0.0229293 |
| SRPK2 | SRSF protein kinase 2 | 0.0228856 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0228519 |
| NBAS | neuroblastoma amplified sequence | 0.0226887 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0225279 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0222446 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0220229 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.0216713 |
| COPA | coatomer protein complex, subunit alpha | 0.021087 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0208739 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.0207517 |
| MED13 | mediator complex subunit 13 | 0.0206372 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0203605 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0200982 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0198466 |
| TMSB4X | thymosin beta 4, X-linked | 0.0195105 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.0192323 |
| UBC | ubiquitin C | 0.0192271 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0192266 |
| CALU | calumenin | 0.0189446 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0188339 |
| POU2F1 | POU class 2 homeobox 1 | 0.0187971 |
| Symbol | Name | Standardized Value |
|---|---|---|
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.09514 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.0762416 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0665154 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.0534106 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0393484 |
| MKI67 | marker of proliferation Ki-67 | -0.0382037 |
| BMP10 | bone morphogenetic protein 10 | -0.0326457 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0295454 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.0285109 |
| FOXP1 | forkhead box P1 | -0.0264275 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | -0.0255926 |
| DIAPH3 | diaphanous-related formin 3 | -0.0246453 |
| CRPPA | CDP-L-ribitol pyrophosphorylase A | -0.0240265 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0219449 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0214458 |
| NAV2 | neuron navigator 2 | -0.0209304 |
| CENPF | centromere protein F, 350/400kDa | -0.020692 |
| UNC13A | unc-13 homolog A (C. elegans) | -0.0206344 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0205199 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0191731 |
| GLI2 | GLI family zinc finger 2 | -0.0186483 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 | -0.0186146 |
| PDE7B | phosphodiesterase 7B | -0.0184967 |
| CENPE | centromere protein E, 312kDa | -0.0181209 |
| GSE1 | Gse1 coiled-coil protein | -0.017985 |
| PKP4 | plakophilin 4 | -0.0179554 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0175959 |
| HJURP | Holliday junction recognition protein | -0.0172529 |
| ITGA10 | integrin, alpha 10 | -0.0161469 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.015447 |
| GCNT1 | glucosaminyl (N-acetyl) transferase 1, core 2 | -0.0151247 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0144351 |
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b | -0.0143354 |
| PDE10A | phosphodiesterase 10A | -0.0141798 |
| TPX2 | TPX2, microtubule-associated | -0.0140588 |
| GOLGB1 | golgin B1 | -0.0136594 |
| CUX1 | cut-like homeobox 1 | -0.0136077 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | -0.0135238 |
| GALNT5 | polypeptide N-acetylgalactosaminyltransferase 5 | -0.0132646 |
| NEBL | nebulette | -0.01302 |
| MYO5C | myosin VC | -0.0129962 |
| SBF2 | SET binding factor 2 | -0.0129794 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | -0.0123386 |
| RAN | RAN, member RAS oncogene family | -0.012302 |
| PRUNE2 | prune homolog 2 (Drosophila) | -0.0122446 |
| AHNAK | AHNAK nucleoprotein | -0.012193 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0118851 |
| DIAPH2 | diaphanous-related formin 2 | -0.0118839 |
| SCMH1 | sex comb on midleg homolog 1 (Drosophila) | -0.0118366 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0118053 |
| TUBB | tubulin, beta class I | -0.0117403 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0117236 |
| CCDC138 | coiled-coil domain containing 138 | -0.0117144 |
| TUBA1B | tubulin, alpha 1b | -0.0116216 |
| INTS6 | integrator complex subunit 6 | -0.011522 |
| FGFR2 | fibroblast growth factor receptor 2 | -0.0113906 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | -0.0113494 |
| PCNX4 | pecanex 4 | -0.0110269 |
| AMOTL2 | angiomotin like 2 | -0.0108012 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.0107796 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0107662 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0107217 |
| RPL31 | ribosomal protein L31 | -0.0106277 |
| EMP3 | epithelial membrane protein 3 | -0.0104529 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0104356 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0102396 |
| EBNA1BP2 | EBNA1 binding protein 2 | -0.0101646 |
| PRC1 | protein regulator of cytokinesis 1 | -0.0101459 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0100867 |
| PA2G4 | proliferation-associated 2G4, 38kDa | -0.00992635 |
| OBSCN | obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF | -0.00992025 |
| SUMF1 | sulfatase modifying factor 1 | -0.00979739 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.00976303 |
| RPL35A | ribosomal protein L35a | -0.00972122 |
| MLIP | muscular LMNA-interacting protein | -0.00966079 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.00958153 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.00955804 |
| NETO2 | neuropilin (NRP) and tolloid (TLL)-like 2 | -0.00953745 |
| KNL1 | kinetochore scaffold 1 | -0.00937972 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0093476 |
| CKAP2 | cytoskeleton associated protein 2 | -0.00929371 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.00927041 |
| EVI5 | ecotropic viral integration site 5 | -0.00926731 |
| SKI | SKI proto-oncogene | -0.00917932 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.00903482 |
| DOCK1 | dedicator of cytokinesis 1 | -0.00901963 |
| AVEN | apoptosis, caspase activation inhibitor | -0.00901593 |
| TMBIM1 | transmembrane BAX inhibitor motif containing 1 | -0.00900129 |
| GOSR1 | golgi SNAP receptor complex member 1 | -0.00896801 |
| CFAP44 | cilia and flagella associated protein 44 | -0.00896417 |
| PRSS23 | protease, serine, 23 | -0.00893921 |
| NUSAP1 | nucleolar and spindle associated protein 1 | -0.0088467 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.00883988 |
| ZNF438 | zinc finger protein 438 | -0.00879804 |
| ARHGAP11A | Rho GTPase activating protein 11A | -0.00869283 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.00864716 |
| FMN1 | formin 1 | -0.0086296 |
| CDK12 | cyclin-dependent kinase 12 | -0.00861494 |
| MMS22L | MMS22-like, DNA repair protein | -0.00858906 |
| CEP128 | centrosomal protein 128kDa | -0.00853169 |
