| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | ULK-101 perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the ULK-101_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SOD2 | superoxide dismutase 2, mitochondrial | 0.146782 |
| HDAC9 | histone deacetylase 9 | 0.0832045 |
| JMJD1C | jumonji domain containing 1C | 0.0631042 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0629283 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0607721 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0592237 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0555991 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0544069 |
| RND3 | Rho family GTPase 3 | 0.0540435 |
| KYNU | kynureninase | 0.0508234 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.047854 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0455464 |
| FNIP1 | folliculin interacting protein 1 | 0.044902 |
| SFTPA2 | surfactant protein A2 | 0.0444883 |
| SQSTM1 | sequestosome 1 | 0.0432676 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0388543 |
| RAB7A | RAB7A, member RAS oncogene family | 0.038676 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0384781 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0378559 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0371488 |
| CANX | calnexin | 0.0361088 |
| NAV2 | neuron navigator 2 | 0.0341057 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0318681 |
| VMP1 | vacuole membrane protein 1 | 0.0318038 |
| SMYD3 | SET and MYND domain containing 3 | 0.0313669 |
| GPC6 | glypican 6 | 0.0301461 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0294864 |
| TNS3 | tensin 3 | 0.0293778 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0285456 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0278326 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0277834 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0269536 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0265071 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0264065 |
| FMNL2 | formin-like 2 | 0.0261285 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0255969 |
| FBXO32 | F-box protein 32 | 0.0252867 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0249428 |
| ERBIN | erbb2 interacting protein | 0.0249155 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0245416 |
| ARFGEF3 | ARFGEF family member 3 | 0.0242213 |
| STAG2 | stromal antigen 2 | 0.02418 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0237994 |
| GOLGB1 | golgin B1 | 0.0235411 |
| SPAG9 | sperm associated antigen 9 | 0.0233506 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0230619 |
| CD44 | CD44 molecule (Indian blood group) | 0.0229515 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0228838 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0228341 |
| MYOF | myoferlin | 0.0226047 |
| DUSP10 | dual specificity phosphatase 10 | 0.0225725 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0217116 |
| C6ORF62 | chromosome 6 open reading frame 62 | 0.0215708 |
| ATXN1 | ataxin 1 | 0.0210005 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0209873 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.020763 |
| CREBRF | CREB3 regulatory factor | 0.0206837 |
| IGF2R | insulin-like growth factor 2 receptor | 0.0206553 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0205619 |
| RPL23 | ribosomal protein L23 | 0.0204373 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.020431 |
| BPTF | bromodomain PHD finger transcription factor | 0.0201897 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0200854 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0200306 |
| VAC14 | Vac14 homolog (S. cerevisiae) | 0.0197012 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0196067 |
| KLHL24 | kelch-like family member 24 | 0.0192571 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0191573 |
| WTAP | Wilms tumor 1 associated protein | 0.0191245 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0190292 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.01894 |
| RASAL2 | RAS protein activator like 2 | 0.0188379 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0187157 |
| GOLGA4 | golgin A4 | 0.018253 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0182017 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0181655 |
| JAK1 | Janus kinase 1 | 0.0180719 |
| MED13 | mediator complex subunit 13 | 0.018031 |
| HLA-E | major histocompatibility complex, class I, E | 0.0180293 |
| DST | dystonin | 0.0179692 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | 0.0179471 |
| APP | amyloid beta (A4) precursor protein | 0.0179108 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0179094 |
| ASPH | aspartate beta-hydroxylase | 0.0178755 |
| SP100 | SP100 nuclear antigen | 0.0174451 |
| KAT6B | K(lysine) acetyltransferase 6B | 0.017401 |
| INTS6 | integrator complex subunit 6 | 0.017227 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0170861 |
| MED13L | mediator complex subunit 13-like | 0.0170282 |
| NT5C2 | 5'-nucleotidase, cytosolic II | 0.0169435 |
| ZHX2 | zinc fingers and homeoboxes 2 | 0.0168603 |
| SERINC3 | serine incorporator 3 | 0.0167057 |
| SDCBP | syndecan binding protein (syntenin) | 0.0165785 |
| CLTC | clathrin, heavy chain (Hc) | 0.0165191 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0164133 |
| ZNF638 | zinc finger protein 638 | 0.0164118 |
| AHNAK | AHNAK nucleoprotein | 0.0161871 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0161742 |
| UTRN | utrophin | 0.0161562 |
| CTSB | cathepsin B | 0.016051 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0975514 |
| FN1 | fibronectin 1 | -0.0690977 |
| FTL | ferritin, light polypeptide | -0.0525279 |
| TMSB10 | thymosin beta 10 | -0.0478997 |
| FRMD4A | FERM domain containing 4A | -0.0474601 |
| MT2A | metallothionein 2A | -0.0453402 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0422691 |
| HLA-B | major histocompatibility complex, class I, B | -0.0364853 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0350698 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0287549 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0276037 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0259007 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0247288 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0230561 |
| RPL35A | ribosomal protein L35a | -0.0220974 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0212953 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.020799 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0205017 |
| THBS1 | thrombospondin 1 | -0.0197485 |
| ADM | adrenomedullin | -0.0195847 |
| COL1A1 | collagen, type I, alpha 1 | -0.0194191 |
| IER3 | immediate early response 3 | -0.0191521 |
| CADM1 | cell adhesion molecule 1 | -0.0186256 |
| PTMA | prothymosin, alpha | -0.0179701 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0176768 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0168218 |
| GNAS | GNAS complex locus | -0.0167765 |
| HLA-A | major histocompatibility complex, class I, A | -0.0165598 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0164816 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.016173 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0161438 |
| PFN1 | profilin 1 | -0.01536 |
| RPL36 | ribosomal protein L36 | -0.01515 |
| HMGA1 | high mobility group AT-hook 1 | -0.0145395 |
| RPLP2 | ribosomal protein, large, P2 | -0.0143845 |
| MT1X | metallothionein 1X | -0.0142744 |
| COL1A2 | collagen, type I, alpha 2 | -0.0142487 |
| SFRP1 | secreted frizzled-related protein 1 | -0.0140541 |
| CENPF | centromere protein F, 350/400kDa | -0.0139797 |
| RTN4 | reticulon 4 | -0.0139394 |
| NDRG1 | N-myc downstream regulated 1 | -0.0134701 |
| FAM162A | family with sequence similarity 162, member A | -0.0134272 |
| EGR1 | early growth response 1 | -0.0134217 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0132597 |
| RPL19 | ribosomal protein L19 | -0.0132337 |
| LRRC7 | leucine rich repeat containing 7 | -0.0132234 |
| VIM | vimentin | -0.0130134 |
| ANLN | anillin, actin binding protein | -0.0124963 |
| LOX | lysyl oxidase | -0.0124748 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0124333 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | -0.012364 |
| TMEM123 | transmembrane protein 123 | -0.0123145 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0122874 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0121719 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0121168 |
| VEGFA | vascular endothelial growth factor A | -0.0120978 |
| RPS19 | ribosomal protein S19 | -0.011976 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0119337 |
| POTEF | POTE ankyrin domain family, member F | -0.0119066 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | -0.0117707 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0117356 |
| CCNL1 | cyclin L1 | -0.0116937 |
| TUBB | tubulin, beta class I | -0.0116648 |
| ACTG1 | actin gamma 1 | -0.011626 |
| DSTN | destrin (actin depolymerizing factor) | -0.0116152 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0116068 |
| SRGN | serglycin | -0.0112985 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0110508 |
| WDR45B | WD repeat domain 45B | -0.0110243 |
| NACA | nascent polypeptide-associated complex alpha subunit | -0.011018 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0108536 |
| DEK | DEK proto-oncogene | -0.0108497 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0108339 |
| PGK1 | phosphoglycerate kinase 1 | -0.0107965 |
| FOSL1 | FOS-like antigen 1 | -0.010697 |
| RPS3 | ribosomal protein S3 | -0.0104884 |
| INSIG1 | insulin induced gene 1 | -0.0104788 |
| KRT19 | keratin 19, type I | -0.0104772 |
| C3 | complement component 3 | -0.0104336 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0103791 |
| MKI67 | marker of proliferation Ki-67 | -0.0103164 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0103072 |
| TPM1 | tropomyosin 1 (alpha) | -0.0101896 |
| CAVIN1 | caveolae associated protein 1 | -0.0101631 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0101058 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.00990003 |
| S100A9 | S100 calcium binding protein A9 | -0.00980345 |
| RPL38 | ribosomal protein L38 | -0.00977387 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.00973906 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.00969839 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.00959066 |
| ERGIC1 | endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 | -0.00958635 |
| TPM4 | tropomyosin 4 | -0.00956933 |
| DEPP1 | DEPP autophagy regulator 1 | -0.00951391 |
| RPS21 | ribosomal protein S21 | -0.00948525 |
| TAPBP | TAP binding protein (tapasin) | -0.00934542 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.00934491 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | -0.00930227 |
| UBE2O | ubiquitin-conjugating enzyme E2O | -0.00930014 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0091652 |
