| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | ULK-101 perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the ULK-101_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.175305 |
| FNDC3B | fibronectin type III domain containing 3B | 0.120392 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.109138 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0984671 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0918441 |
| FAM13A | family with sequence similarity 13, member A | 0.089357 |
| B2M | beta-2-microglobulin | 0.0762733 |
| CALR | calreticulin | 0.0637957 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0629952 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0592186 |
| CANX | calnexin | 0.0591503 |
| ZNF395 | zinc finger protein 395 | 0.0570712 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0560006 |
| NDRG1 | N-myc downstream regulated 1 | 0.0522213 |
| EGFR | epidermal growth factor receptor | 0.0496033 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0469367 |
| LMAN1 | lectin, mannose-binding, 1 | 0.0468984 |
| FNIP1 | folliculin interacting protein 1 | 0.0467586 |
| GOLGA4 | golgin A4 | 0.046261 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0452486 |
| MYO1E | myosin IE | 0.0444019 |
| ENO1 | enolase 1, (alpha) | 0.0423809 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0411819 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0411279 |
| CCNI | cyclin I | 0.0410186 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0408084 |
| RYBP | RING1 and YY1 binding protein | 0.040736 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0406288 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0404949 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0403791 |
| RPS8 | ribosomal protein S8 | 0.0395975 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0388088 |
| MAGT1 | magnesium transporter 1 | 0.038627 |
| ADM | adrenomedullin | 0.0382114 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0379057 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0377848 |
| WASF2 | WAS protein family, member 2 | 0.0372007 |
| SBF2 | SET binding factor 2 | 0.0370568 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0370393 |
| COPA | coatomer protein complex, subunit alpha | 0.0365352 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0361797 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.035449 |
| SLC41A2 | solute carrier family 41 (magnesium transporter), member 2 | 0.0353181 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | 0.0352543 |
| HLA-A | major histocompatibility complex, class I, A | 0.0351507 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0347595 |
| JMJD1C | jumonji domain containing 1C | 0.0347472 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0345947 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0334187 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0332858 |
| INSIG2 | insulin induced gene 2 | 0.0329063 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0325143 |
| YAP1 | Yes-associated protein 1 | 0.0322237 |
| KYNU | kynureninase | 0.0321903 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0315959 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0315896 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0314075 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0313692 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0310778 |
| ATP13A3 | ATPase type 13A3 | 0.0308973 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0306928 |
| RPL28 | ribosomal protein L28 | 0.0304697 |
| SEC24D | SEC24 family member D | 0.0304426 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.030366 |
| RIOK3 | RIO kinase 3 | 0.0303442 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0303425 |
| PTGES2 | prostaglandin E synthase 2 | 0.030054 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | 0.0297458 |
| YBX1 | Y box binding protein 1 | 0.0297137 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0294472 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0291069 |
| PKM | pyruvate kinase, muscle | 0.0289127 |
| KMT2A | lysine (K)-specific methyltransferase 2A | 0.0286992 |
| MORF4L2 | mortality factor 4 like 2 | 0.0282598 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0280957 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0277748 |
| SEC24A | SEC24 family member A | 0.0277174 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0276157 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.0274095 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0272636 |
| SP100 | SP100 nuclear antigen | 0.0272198 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0270507 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0269064 |
| TMF1 | TATA element modulatory factor 1 | 0.0268455 |
| XPO1 | exportin 1 | 0.0267973 |
| HELZ | helicase with zinc finger | 0.0266423 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0265245 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | 0.0264359 |
| ZNF638 | zinc finger protein 638 | 0.0260487 |
| UBC | ubiquitin C | 0.0259694 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0258306 |
| PGK1 | phosphoglycerate kinase 1 | 0.0255358 |
| PTN | pleiotrophin | 0.0254043 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0253856 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | 0.0253641 |
| DSTN | destrin (actin depolymerizing factor) | 0.0252945 |
| PRKCA | protein kinase C, alpha | 0.0250664 |
| CLEC1B | C-type lectin domain family 1, member B | 0.0248662 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0248229 |
| PTMA | prothymosin, alpha | 0.024678 |
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | -0.146787 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0999665 |
| TMSB10 | thymosin beta 10 | -0.0993182 |
| GLIS3 | GLIS family zinc finger 3 | -0.0587413 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.057432 |
| VCL | vinculin | -0.0530433 |
| MT2A | metallothionein 2A | -0.0530271 |
| CALD1 | caldesmon 1 | -0.0506059 |
| FN1 | fibronectin 1 | -0.0496735 |
| SMAD3 | SMAD family member 3 | -0.0486305 |
| SRPK2 | SRSF protein kinase 2 | -0.0465542 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0446879 |
| HLA-B | major histocompatibility complex, class I, B | -0.0396928 |
| FSCN1 | fascin actin-bundling protein 1 | -0.0386733 |
| LOXL2 | lysyl oxidase-like 2 | -0.0383282 |
| CDK6 | cyclin-dependent kinase 6 | -0.0379651 |
| NRP1 | neuropilin 1 | -0.0378769 |
| HMGA2 | high mobility group AT-hook 2 | -0.0376716 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0373631 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0344128 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0340544 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0334244 |
| TAGLN2 | transgelin 2 | -0.033076 |
| COL1A2 | collagen, type I, alpha 2 | -0.0326571 |
| AHR | aryl hydrocarbon receptor | -0.0325982 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0318793 |
| MT1X | metallothionein 1X | -0.0317388 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0317281 |
| RASAL2 | RAS protein activator like 2 | -0.0315414 |
| TMSB4X | thymosin beta 4, X-linked | -0.0312878 |
| RBM25 | RNA binding motif protein 25 | -0.0312023 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0304861 |
| ZNF644 | zinc finger protein 644 | -0.0304313 |
| AOPEP | aminopeptidase O (putative) | -0.0303186 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0301882 |
| COL7A1 | collagen, type VII, alpha 1 | -0.0300071 |
| FAM20C | family with sequence similarity 20, member C | -0.0296017 |
| EFNA5 | ephrin-A5 | -0.0290543 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0288252 |
| OGA | O-GlcNAcase | -0.0288154 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0286618 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0284885 |
| RPS3 | ribosomal protein S3 | -0.028014 |
| DENND4A | DENN/MADD domain containing 4A | -0.0279809 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | -0.0279673 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0279352 |
| MAPK8 | mitogen-activated protein kinase 8 | -0.027881 |
| HPCAL1 | hippocalcin-like 1 | -0.0278195 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0276076 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0272451 |
| FAT1 | FAT atypical cadherin 1 | -0.0269529 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0267839 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0262866 |
| C1D | C1D nuclear receptor corepressor | -0.0262542 |
| NKTR | natural killer cell triggering receptor | -0.0261434 |
| PXMP2 | peroxisomal membrane protein 2, 22kDa | -0.0255095 |
| COL1A1 | collagen, type I, alpha 1 | -0.0254615 |
| TNNC1 | troponin C type 1 (slow) | -0.0253762 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0253531 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | -0.0250453 |
| AHNAK | AHNAK nucleoprotein | -0.0249279 |
| RRBP1 | ribosome binding protein 1 | -0.0248098 |
| PCM1 | pericentriolar material 1 | -0.0246327 |
| COL5A2 | collagen, type V, alpha 2 | -0.0244337 |
| OSMR | oncostatin M receptor | -0.0244264 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0240829 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0238447 |
| TRIM9 | tripartite motif containing 9 | -0.0237217 |
| FBXW11 | F-box and WD repeat domain containing 11 | -0.0235226 |
| STC1 | stanniocalcin 1 | -0.0234637 |
| LUC7L | LUC7-like (S. cerevisiae) | -0.023161 |
| FKBP10 | FK506 binding protein 10, 65 kDa | -0.0231514 |
| ANKRD36C | ankyrin repeat domain 36C | -0.023101 |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 | -0.022873 |
| PALLD | palladin, cytoskeletal associated protein | -0.0228097 |
| STK17A | serine/threonine kinase 17a | -0.022646 |
| ZNF133 | zinc finger protein 133 | -0.0226363 |
| HIPK2 | homeodomain interacting protein kinase 2 | -0.0225059 |
| RSU1 | Ras suppressor protein 1 | -0.0224416 |
| SYNPO | synaptopodin | -0.0223296 |
| MRTFA | myocardin related transcription factor A | -0.022195 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0220533 |
| VPS37A | vacuolar protein sorting 37 homolog A (S. cerevisiae) | -0.0220045 |
| UBE3A | ubiquitin protein ligase E3A | -0.0218796 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0217573 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0217041 |
| CTNNAL1 | catenin (cadherin-associated protein), alpha-like 1 | -0.0216836 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | -0.0216564 |
| UFM1 | ubiquitin-fold modifier 1 | -0.0212874 |
| ZHX3 | zinc fingers and homeoboxes 3 | -0.0211307 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0210675 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0210401 |
| DIAPH3 | diaphanous-related formin 3 | -0.0209604 |
| NRXN3 | neurexin 3 | -0.0209217 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) | -0.0206349 |
| RAI14 | retinoic acid induced 14 | -0.0204966 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0204423 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0203836 |
| SUB1 | SUB1 homolog (S. cerevisiae) | -0.0202804 |
| SERF2 | small EDRK-rich factor 2 | -0.0201421 |
