| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | ULK-101 perturbation in SW1417 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the ULK-101_SW1417 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0901386 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0659243 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0618264 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0610265 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0597712 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0538276 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0455837 |
| MYO1E | myosin IE | 0.0451971 |
| NEBL | nebulette | 0.0442243 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0438039 |
| BCL2L1 | BCL2-like 1 | 0.0416765 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0409407 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0404253 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0397244 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0394637 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0387292 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0369848 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0355204 |
| RPL12 | ribosomal protein L12 | 0.0351898 |
| RPLP0 | ribosomal protein, large, P0 | 0.0344746 |
| ADAM19 | ADAM metallopeptidase domain 19 | 0.0330707 |
| PCBP2 | poly(rC) binding protein 2 | 0.0314574 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0312362 |
| NRP1 | neuropilin 1 | 0.0309764 |
| RPS6 | ribosomal protein S6 | 0.030906 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | 0.0308625 |
| RPL18 | ribosomal protein L18 | 0.0296195 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0291971 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0291111 |
| RPLP1 | ribosomal protein, large, P1 | 0.0288269 |
| EZR | ezrin | 0.028601 |
| VMP1 | vacuole membrane protein 1 | 0.0284927 |
| EGFR | epidermal growth factor receptor | 0.0281564 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0281095 |
| SLC38A1 | solute carrier family 38, member 1 | 0.027392 |
| B2M | beta-2-microglobulin | 0.0271955 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0270977 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0269188 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0264819 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0258721 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.024768 |
| TJP1 | tight junction protein 1 | 0.0245825 |
| RPS4X | ribosomal protein S4, X-linked | 0.0240525 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | 0.0239774 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | 0.0239633 |
| RPL23 | ribosomal protein L23 | 0.0239611 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0237726 |
| KCNH8 | potassium channel, voltage gated eag related subfamily H, member 8 | 0.0237594 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0236325 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0235605 |
| SNX9 | sorting nexin 9 | 0.0235384 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0230711 |
| COG5 | component of oligomeric golgi complex 5 | 0.0228428 |
| ZNF292 | zinc finger protein 292 | 0.022718 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | 0.0226684 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0225397 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0223103 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | 0.0219888 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0218005 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0216466 |
| HM13 | histocompatibility (minor) 13 | 0.0216067 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.0215358 |
| RCOR1 | REST corepressor 1 | 0.0214073 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0211705 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0208843 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0208178 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0207946 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0207062 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.0203241 |
| TOP1 | topoisomerase (DNA) I | 0.0202137 |
| SMAD3 | SMAD family member 3 | 0.0201553 |
| RPS8 | ribosomal protein S8 | 0.0198471 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0198012 |
| JUN | jun proto-oncogene | 0.019799 |
| TES | testin LIM domain protein | 0.0196471 |
| PGK1 | phosphoglycerate kinase 1 | 0.0196096 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | 0.0193591 |
| JMJD1C | jumonji domain containing 1C | 0.0193449 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0192158 |
| SIK3 | SIK family kinase 3 | 0.0189434 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.01837 |
| KMT5B | lysine methyltransferase 5B | 0.0183522 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0183488 |
| EXOC4 | exocyst complex component 4 | 0.0182022 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.017893 |
| ERBIN | erbb2 interacting protein | 0.0177563 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0177488 |
| PKM | pyruvate kinase, muscle | 0.0176946 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0176705 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0175099 |
| DIAPH1 | diaphanous-related formin 1 | 0.0174862 |
| PERP | PERP, TP53 apoptosis effector | 0.0173858 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.017364 |
| RPL27A | ribosomal protein L27a | 0.017316 |
| EGR1 | early growth response 1 | 0.0172835 |
| SVIL | supervillin | 0.017203 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.0170413 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0170162 |
| EHBP1 | EH domain binding protein 1 | 0.0170108 |
| SETX | senataxin | 0.0165952 |
| Symbol | Name | Standardized Value |
|---|---|---|
| H1-0 | H1.0 linker histone | -0.0320632 |
| RBM39 | RNA binding motif protein 39 | -0.0317354 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0312133 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.0234978 |
| HSPA8 | heat shock 70kDa protein 8 | -0.0206856 |
| OGA | O-GlcNAcase | -0.0202224 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0195109 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0192985 |
| RYBP | RING1 and YY1 binding protein | -0.018098 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | -0.0180053 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0179591 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0175505 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0168785 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.016702 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0165624 |
| PTMA | prothymosin, alpha | -0.0165145 |
| NKTR | natural killer cell triggering receptor | -0.0164667 |
| TRA2B | transformer 2 beta homolog (Drosophila) | -0.0163437 |
| NCKAP1 | NCK-associated protein 1 | -0.0160896 |
| MAP4 | microtubule-associated protein 4 | -0.0160007 |
| UBQLN1 | ubiquilin 1 | -0.0156538 |
| GNAS | GNAS complex locus | -0.0154052 |
| ZNF706 | zinc finger protein 706 | -0.0152891 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0151276 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0149081 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0147954 |
| CCNL1 | cyclin L1 | -0.0145152 |
| MKI67 | marker of proliferation Ki-67 | -0.0142503 |
| RNF149 | ring finger protein 149 | -0.0138596 |
| CCND1 | cyclin D1 | -0.0134598 |
| RPL6 | ribosomal protein L6 | -0.0132684 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0131447 |
| KAT6A | K(lysine) acetyltransferase 6A | -0.0130205 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | -0.0128736 |
| TMEM47 | transmembrane protein 47 | -0.0128615 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0127789 |
| EPCAM | epithelial cell adhesion molecule | -0.0127213 |
| RPS2 | ribosomal protein S2 | -0.0126832 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.0126669 |
| PLEC | plectin | -0.0126541 |
| PRELID2 | PRELI domain containing 2 | -0.0121976 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | -0.0121391 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.012041 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | -0.0119876 |
| TCERG1 | transcription elongation regulator 1 | -0.0118566 |
| XPO1 | exportin 1 | -0.0118273 |
| RPS21 | ribosomal protein S21 | -0.0118225 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0117447 |
| MEMO1 | mediator of cell motility 1 | -0.0114098 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.0113602 |
| PRRC2C | proline-rich coiled-coil 2C | -0.011345 |
| IER3 | immediate early response 3 | -0.011308 |
| MEF2A | myocyte enhancer factor 2A | -0.0112992 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0112679 |
| RPRD1B | regulation of nuclear pre-mRNA domain containing 1B | -0.0111044 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0110997 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.011097 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | -0.0110872 |
| DENND1A | DENN/MADD domain containing 1A | -0.0110414 |
| FMR1 | fragile X mental retardation 1 | -0.0109509 |
| USP24 | ubiquitin specific peptidase 24 | -0.0108229 |
| TXNL1 | thioredoxin-like 1 | -0.0107735 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0107639 |
| H1-4 | H1.4 linker histone, cluster member | -0.0107628 |
| RBM25 | RNA binding motif protein 25 | -0.0107264 |
| SWAP70 | SWAP switching B-cell complex 70kDa subunit | -0.010552 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | -0.0105256 |
| OSBPL3 | oxysterol binding protein-like 3 | -0.0104222 |
| PPME1 | protein phosphatase methylesterase 1 | -0.0103751 |
| CAPRIN1 | cell cycle associated protein 1 | -0.0103692 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0102288 |
| ACTN4 | actinin, alpha 4 | -0.0102268 |
| TMEM39A | transmembrane protein 39A | -0.0101883 |
| TFRC | transferrin receptor | -0.0101179 |
| SETD5 | SET domain containing 5 | -0.0101095 |
| FLNA | filamin A, alpha | -0.0100605 |
| DUSP5 | dual specificity phosphatase 5 | -0.0100555 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.00997992 |
| EIF4H | eukaryotic translation initiation factor 4H | -0.00990003 |
| NCOR1 | nuclear receptor corepressor 1 | -0.00988533 |
| RHEB | Ras homolog enriched in brain | -0.00981247 |
| ZC3H13 | zinc finger CCCH-type containing 13 | -0.00974124 |
| CKAP5 | cytoskeleton associated protein 5 | -0.00972377 |
| ADAR | adenosine deaminase, RNA-specific | -0.00967597 |
| RPL38 | ribosomal protein L38 | -0.00967531 |
| MSMO1 | methylsterol monooxygenase 1 | -0.00965003 |
| HACD2 | 3-hydroxyacyl-CoA dehydratase 2 | -0.00960214 |
| RTN4 | reticulon 4 | -0.00959369 |
| STIP1 | stress-induced phosphoprotein 1 | -0.00957186 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 | -0.00954515 |
| RNF145 | ring finger protein 145 | -0.00945889 |
| RBM33 | RNA binding motif protein 33 | -0.00945088 |
| SLC25A3 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 | -0.0094436 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.00941515 |
| ANLN | anillin, actin binding protein | -0.00937868 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.00936953 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.00935908 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.00934923 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | -0.00933844 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | -0.00932206 |
