| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | ULK-101 perturbation in hTERT-HPNE cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the ULK-101_hTERT-HPNE drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| STC1 | stanniocalcin 1 | 0.125574 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.093845 |
| HMGA2 | high mobility group AT-hook 2 | 0.0828596 |
| B2M | beta-2-microglobulin | 0.0702201 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0677713 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0653683 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0639886 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0609327 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0576211 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0573273 |
| CD44 | CD44 molecule (Indian blood group) | 0.0552096 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.05443 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0524466 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0463405 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | 0.0446272 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0435304 |
| MCL1 | myeloid cell leukemia 1 | 0.0435146 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0426493 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0421775 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0421527 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0420735 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0419516 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0411933 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0407884 |
| LOX | lysyl oxidase | 0.0401896 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0382095 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0372695 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.037196 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0370617 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0365567 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0359374 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0356962 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0353798 |
| NAV2 | neuron navigator 2 | 0.0352918 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.034051 |
| VMP1 | vacuole membrane protein 1 | 0.0332756 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0328965 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.032563 |
| SPAG9 | sperm associated antigen 9 | 0.0317551 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0312839 |
| SLC38A2 | solute carrier family 38, member 2 | 0.029754 |
| MYO10 | myosin X | 0.0294716 |
| FMNL2 | formin-like 2 | 0.0291624 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0290119 |
| HDAC9 | histone deacetylase 9 | 0.028778 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0283919 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0279185 |
| FNIP1 | folliculin interacting protein 1 | 0.0275008 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0273812 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0269839 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0259032 |
| IL6ST | interleukin 6 signal transducer | 0.0258119 |
| SQSTM1 | sequestosome 1 | 0.0251872 |
| PCBP2 | poly(rC) binding protein 2 | 0.0250975 |
| ENO1 | enolase 1, (alpha) | 0.0250723 |
| INTS6 | integrator complex subunit 6 | 0.0248008 |
| LDHA | lactate dehydrogenase A | 0.023566 |
| VIM | vimentin | 0.0227999 |
| ANXA5 | annexin A5 | 0.0222302 |
| MT2A | metallothionein 2A | 0.0218857 |
| RASA2 | RAS p21 protein activator 2 | 0.0217691 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0216332 |
| CLIC4 | chloride intracellular channel 4 | 0.021614 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0215606 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0213549 |
| HLA-A | major histocompatibility complex, class I, A | 0.0212024 |
| DNER | delta/notch-like EGF repeat containing | 0.0209661 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0205656 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.020473 |
| RND3 | Rho family GTPase 3 | 0.0204001 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0203147 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0201824 |
| VCL | vinculin | 0.0201014 |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 | 0.0200285 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0199861 |
| SMYD3 | SET and MYND domain containing 3 | 0.0198707 |
| GK | glycerol kinase | 0.0198497 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0198331 |
| HLA-E | major histocompatibility complex, class I, E | 0.01981 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0194977 |
| USP34 | ubiquitin specific peptidase 34 | 0.0194336 |
| BRD2 | bromodomain containing 2 | 0.0193965 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.019323 |
| VEGFC | vascular endothelial growth factor C | 0.019137 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0191289 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.0191245 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0191207 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0190483 |
| FNBP1 | formin binding protein 1 | 0.0189869 |
| SERINC1 | serine incorporator 1 | 0.0189217 |
| HDLBP | high density lipoprotein binding protein | 0.0188685 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0187111 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0186328 |
| PRELID2 | PRELI domain containing 2 | 0.0186104 |
| IGFBP7 | insulin-like growth factor binding protein 7 | 0.0185625 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0185171 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0181054 |
| GOLGA4 | golgin A4 | 0.0180866 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0180566 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | 0.018053 |
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | -0.162142 |
| COL1A1 | collagen, type I, alpha 1 | -0.156344 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.10077 |
| COL1A2 | collagen, type I, alpha 2 | -0.0829698 |
| FN1 | fibronectin 1 | -0.0805049 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.079449 |
| MMP1 | matrix metallopeptidase 1 | -0.0720624 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.0719486 |
| COL6A2 | collagen, type VI, alpha 2 | -0.070259 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | -0.0578785 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0569637 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0560673 |
| ADAMTS12 | ADAM metallopeptidase with thrombospondin type 1 motif, 12 | -0.0542742 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0535055 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0517171 |
| GREM1 | gremlin 1, DAN family BMP antagonist | -0.0502443 |
| CAVIN1 | caveolae associated protein 1 | -0.0501086 |
| TMSB10 | thymosin beta 10 | -0.0491798 |
| EMP1 | epithelial membrane protein 1 | -0.0478205 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0455128 |
| OXR1 | oxidation resistance 1 | -0.0445116 |
| FBN1 | fibrillin 1 | -0.0383057 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0365448 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0344479 |
| PRRX1 | paired related homeobox 1 | -0.0304064 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0303729 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0286063 |
| PRSS23 | protease, serine, 23 | -0.028557 |
| VCAN | versican | -0.0281512 |
| CDH13 | cadherin 13 | -0.0279395 |
| KIAA1549L | KIAA1549-like | -0.0275144 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0269446 |
| RPL35A | ribosomal protein L35a | -0.0253068 |
| PDE8A | phosphodiesterase 8A | -0.0250913 |
| RAI14 | retinoic acid induced 14 | -0.0244222 |
| COL5A3 | collagen, type V, alpha 3 | -0.0243777 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0231908 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0230194 |
| CCDC102B | coiled-coil domain containing 102B | -0.0227565 |
| SEPTIN11 | septin 11 | -0.0212219 |
| NPTX1 | neuronal pentraxin I | -0.0195508 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0190964 |
| ERGIC1 | endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 | -0.0186959 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0185339 |
| CLMP | CXADR-like membrane protein | -0.0184779 |
| COL5A1 | collagen, type V, alpha 1 | -0.0182136 |
| SASH1 | SAM and SH3 domain containing 1 | -0.0181493 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0181103 |
| BAALC | brain and acute leukemia, cytoplasmic | -0.0179337 |
| HAS2 | hyaluronan synthase 2 | -0.0177948 |
| LAMB3 | laminin, beta 3 | -0.0176376 |
| IER3 | immediate early response 3 | -0.0174297 |
| FTL | ferritin, light polypeptide | -0.0167338 |
| S100A6 | S100 calcium binding protein A6 | -0.0164819 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0161999 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.0160754 |
| ITGA11 | integrin, alpha 11 | -0.0159813 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0157411 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0156538 |
| PTMA | prothymosin, alpha | -0.0155415 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0149079 |
| EDNRA | endothelin receptor type A | -0.0144175 |
| MED13L | mediator complex subunit 13-like | -0.0138314 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) | -0.013805 |
| CUX1 | cut-like homeobox 1 | -0.013674 |
| NREP | neuronal regeneration related protein | -0.0135856 |
| DDR2 | discoidin domain receptor tyrosine kinase 2 | -0.0135093 |
| PDGFRB | platelet-derived growth factor receptor, beta polypeptide | -0.0133757 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0133743 |
| TCEAL9 | transcription elongation factor A like 9 | -0.0132446 |
| SAMD3 | sterile alpha motif domain containing 3 | -0.0131811 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 | -0.0130904 |
| RPS13 | ribosomal protein S13 | -0.0129988 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0128119 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0128104 |
| PRR16 | proline rich 16 | -0.0128026 |
| CHSY3 | chondroitin sulfate synthase 3 | -0.0127489 |
| SPRY4 | sprouty homolog 4 (Drosophila) | -0.0127476 |
| POTEF | POTE ankyrin domain family, member F | -0.0127302 |
| KCNE4 | potassium channel, voltage gated subfamily E regulatory beta subunit 4 | -0.0126853 |
| COL3A1 | collagen, type III, alpha 1 | -0.0124453 |
| ITPRIPL2 | inositol 1,4,5-trisphosphate receptor interacting protein-like 2 | -0.0124415 |
| RPLP2 | ribosomal protein, large, P2 | -0.0123849 |
| VEPH1 | ventricular zone expressed PH domain-containing 1 | -0.0122426 |
| NOTCH3 | notch 3 | -0.0121642 |
| RPS3 | ribosomal protein S3 | -0.0121271 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0120604 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0119445 |
| CA12 | carbonic anhydrase XII | -0.0119276 |
| TBX2 | T-box 2 | -0.0118399 |
| NID2 | nidogen 2 (osteonidogen) | -0.0117549 |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) | -0.0116682 |
| PARVA | parvin, alpha | -0.0115945 |
| RRBP1 | ribosome binding protein 1 | -0.0115695 |
| COL27A1 | collagen, type XXVII, alpha 1 | -0.0115092 |
| CHSY1 | chondroitin sulfate synthase 1 | -0.0114755 |
| ZFHX3 | zinc finger homeobox 3 | -0.0114053 |
| CENPF | centromere protein F, 350/400kDa | -0.0113714 |
| POMP | proteasome maturation protein | -0.0111682 |
| CREB3L1 | cAMP responsive element binding protein 3-like 1 | -0.0109441 |
