UNC119 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description unc-119 homolog (C. elegans)|This gene is specifically expressed in the photoreceptors in the retina. The encoded product shares strong homology with the C. elegans unc119 protein and it can functionally complement the C. elegans unc119 mutation. It has been localized to the photoreceptor synapses in the outer plexiform layer of the retina, and suggested to play a role in the mechanism of photoreceptor neurotransmitter release through the synaptic vesicle cycle. Two transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 9094)
External Link http://www.ncbi.nlm.nih.gov/gene/9094
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95 interacting proteins for UNC119 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
AAGAB alpha- and gamma-adaptin binding protein
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ANKRD24 ankyrin repeat domain 24
ANXA1 annexin A1
ANXA3 annexin A3
ANXA7 annexin A7
ARL15 ADP-ribosylation factor-like 15
ARL2 ADP-ribosylation factor-like 2
ARL3 ADP-ribosylation factor-like 3
ARL4D ADP-ribosylation factor-like 4D
ASH2L ash2 (absent, small, or homeotic)-like (Drosophila)
BCR breakpoint cluster region
BRIX1 BRX1, biogenesis of ribosomes
BTBD2 BTB (POZ) domain containing 2
C16ORF74 chromosome 16 open reading frame 74
CBX8 chromobox homolog 8
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
CD247 CD247 molecule
CD3E CD3e molecule, epsilon (CD3-TCR complex)
CD4 CD4 molecule
CDC42 cell division cycle 42
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
CETN3 centrin, EF-hand protein, 3
CKMT2 creatine kinase, mitochondrial 2 (sarcomeric)
CKS2 CDC28 protein kinase regulatory subunit 2
COX17 COX17 cytochrome c oxidase copper chaperone
CYB561D2 cytochrome b561 family, member D2
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa
ERH enhancer of rudimentary homolog (Drosophila)
FKBPL FK506 binding protein like
FXYD6 FXYD domain containing ion transport regulator 6
FYN FYN proto-oncogene, Src family tyrosine kinase
GIPC2 GIPC PDZ domain containing family, member 2
GNAT1 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1
GSTM4 glutathione S-transferase mu 4
GUSBP1 glucuronidase, beta pseudogene 1
HCK HCK proto-oncogene, Src family tyrosine kinase
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HMGB1 high mobility group box 1
HSPB3 heat shock 27kDa protein 3
HSPE1 heat shock 10kDa protein 1
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
IL5RA interleukin 5 receptor, alpha
ITSN1 intersectin 1 (SH3 domain protein)
KDM1A lysine (K)-specific demethylase 1A
LAMA4 laminin, alpha 4
LCK LCK proto-oncogene, Src family tyrosine kinase
LIG4 ligase IV, DNA, ATP-dependent
LUC7L2 LUC7-like 2 (S. cerevisiae)
LYN LYN proto-oncogene, Src family tyrosine kinase
MAPK10 mitogen-activated protein kinase 10
MAPK8IP2 mitogen-activated protein kinase 8 interacting protein 2
MPHOSPH6 M-phase phosphoprotein 6
MRPS12 mitochondrial ribosomal protein S12
NPHP3 nephronophthisis 3 (adolescent)
ORAI2 ORAI calcium release-activated calcium modulator 2
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)
PAPSS1 3'-phosphoadenosine 5'-phosphosulfate synthase 1
PCDHA4 protocadherin alpha 4
PFN1 profilin 1
PHF10 PHD finger protein 10
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PPA1 pyrophosphatase (inorganic) 1
PPAP2C phosphatidic acid phosphatase type 2C
PSMD11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
PTPRS protein tyrosine phosphatase, receptor type, S
QTRT1 queuine tRNA-ribosyltransferase 1
RAP1B RAP1B, member of RAS oncogene family
RCC1 regulator of chromosome condensation 1
RFC5 replication factor C (activator 1) 5, 36.5kDa
RGL2 ral guanine nucleotide dissociation stimulator-like 2
RP2 retinitis pigmentosa 2 (X-linked recessive)
RPA2 replication protein A2, 32kDa
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5
RUFY3 RUN and FYVE domain containing 3
S100A4 S100 calcium binding protein A4
S100A8 S100 calcium binding protein A8
SAT1 spermidine/spermine N1-acetyltransferase 1
SEPHS1 selenophosphate synthetase 1
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SMN2 survival of motor neuron 2, centromeric
SULT1E1 sulfotransferase family 1E, estrogen-preferring, member 1
TK1 thymidine kinase 1, soluble
TMSB4X thymosin beta 4, X-linked
TP53BP2 tumor protein p53 binding protein 2
TP53I3 tumor protein p53 inducible protein 3
TRDMT1 tRNA aspartic acid methyltransferase 1
TSC22D1 TSC22 domain family, member 1
UBE2B ubiquitin-conjugating enzyme E2B
UBE2I ubiquitin-conjugating enzyme E2I
UBQLN4 ubiquilin 4
ZFP64 ZFP64 zinc finger protein
ZNF24 zinc finger protein 24