UNC5B Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description unc-5 homolog B (C. elegans)|This gene encodes a member of the netrin family of receptors. This particular protein mediates the repulsive effect of netrin-1 and is a vascular netrin receptor. This encoded protein is also in a group of proteins called dependence receptors (DpRs) which are involved in pro- and anti-apoptotic processes. Many DpRs are involved in embryogenesis and in cancer progression. Two alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Oct 2011] (NCBI Entrez Gene Database, 219699)
External Link http://www.ncbi.nlm.nih.gov/gene/219699
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13 interacting proteins for UNC5B from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
CASP3 caspase 3, apoptosis-related cysteine peptidase
CDC42 cell division cycle 42
DAPK1 death-associated protein kinase 1
FYN FYN proto-oncogene, Src family tyrosine kinase
NEO1 neogenin 1
NTN1 netrin 1
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
RHOU ras homolog family member U
TUBG1 tubulin, gamma 1
UBC ubiquitin C