UNG Gene Set

Dataset MSigDB Cancer Gene Co-expression Modules
Category transcriptomics
Type co-expressed gene
Description uracil-DNA glycosylase|This gene encodes one of several uracil-DNA glycosylases. One important function of uracil-DNA glycosylases is to prevent mutagenesis by eliminating uracil from DNA molecules by cleaving the N-glycosylic bond and initiating the base-excision repair (BER) pathway. Uracil bases occur from cytosine deamination or misincorporation of dUMP residues. Alternative promoter usage and splicing of this gene leads to two different isoforms: the mitochondrial UNG1 and the nuclear UNG2. The UNG2 term was used as a previous symbol for the CCNO gene (GeneID 10309), which has been confused with this gene, in the literature and some databases. [provided by RefSeq, Nov 2010] (NCBI Entrez Gene Database, 7374)
External Link http://www.broadinstitute.org/gsea/msigdb/cards/MORF_UNG
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Genes

76 co-expressed genes for UNG from the MSigDB Cancer Gene Co-expression Modules dataset.

Symbol Name
AHSA1 AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)
AIMP2 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2
ALG8 ALG8, alpha-1,3-glucosyltransferase
ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
ATP5G3 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9)
ATP5J ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6
BANF1 barrier to autointegration factor 1
BAZ1B bromodomain adjacent to zinc finger domain, 1B
C1QBP complement component 1, q subcomponent binding protein
CCT2 chaperonin containing TCP1, subunit 2 (beta)
CCT3 chaperonin containing TCP1, subunit 3 (gamma)
CCT5 chaperonin containing TCP1, subunit 5 (epsilon)
CDC23 cell division cycle 23
CDK4 cyclin-dependent kinase 4
COPS5 COP9 signalosome subunit 5
CYCS cytochrome c, somatic
DDX1 DEAD (Asp-Glu-Ala-Asp) box helicase 1
DOCK3 dedicator of cytokinesis 3
EIF3B eukaryotic translation initiation factor 3, subunit B
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1
FEN1 flap structure-specific endonuclease 1
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GSPT1 G1 to S phase transition 1
H2AFZ H2A histone family, member Z
HAT1 histone acetyltransferase 1
HCCS holocytochrome c synthase
HDAC2 histone deacetylase 2
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1
HNRNPA3 heterogeneous nuclear ribonucleoprotein A3
HNRNPAB heterogeneous nuclear ribonucleoprotein A/B
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
HSPA9 heat shock 70kDa protein 9 (mortalin)
HSPE1 heat shock 10kDa protein 1
ICE1 interactor of little elongation complex ELL subunit 1
KARS lysyl-tRNA synthetase
KIAA0101 KIAA0101
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
MAGOH mago-nashi homolog, proliferation-associated (Drosophila)
MFAP1 microfibrillar-associated protein 1
MRPL19 mitochondrial ribosomal protein L19
MRPL3 mitochondrial ribosomal protein L3
MRPS18B mitochondrial ribosomal protein S18B
MSH2 mutS homolog 2
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase
NAA10 N(alpha)-acetyltransferase 10, NatA catalytic subunit
NDUFAB1 NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa
NDUFS3 NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase)
NHP2 NHP2 ribonucleoprotein
NSDHL NAD(P) dependent steroid dehydrogenase-like
NUDC nudC nuclear distribution protein
PCNA proliferating cell nuclear antigen
PDCD6 programmed cell death 6
POLE3 polymerase (DNA directed), epsilon 3, accessory subunit
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa
POP5 processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae)
PPM1G protein phosphatase, Mg2+/Mn2+ dependent, 1G
PRMT1 protein arginine methyltransferase 1
PSMB2 proteasome (prosome, macropain) subunit, beta type, 2
PSMD7 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
RAD23B RAD23 homolog B (S. cerevisiae)
RBM14 RNA binding motif protein 14
RFC4 replication factor C (activator 1) 4, 37kDa
RPA1 replication protein A1, 70kDa
SET SET nuclear proto-oncogene
SHFM1 split hand/foot malformation (ectrodactyly) type 1
SNRPA1 small nuclear ribonucleoprotein polypeptide A'
SOD1 superoxide dismutase 1, soluble
SRSF1 serine/arginine-rich splicing factor 1
SSBP1 single-stranded DNA binding protein 1, mitochondrial
TMEM106C transmembrane protein 106C
TRIM28 tripartite motif containing 28
TUFM Tu translation elongation factor, mitochondrial
UNG uracil-DNA glycosylase
UTP18 UTP18 small subunit (SSU) processome component homolog (yeast)
VBP1 von Hippel-Lindau binding protein 1
VDAC1 voltage-dependent anion channel 1