USF2 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description upstream transcription factor 2, c-fos interacting|This gene encodes a member of the basic helix-loop-helix leucine zipper family, and can function as a cellular transcription factor. The encoded protein can activate transcription through pyrimidine-rich initiator (Inr) elements and E-box motifs. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 7392)
Similar Terms
Downloads & Tools

Genes

370 genes differentially expressed following the USF2 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
CD6 CD6 molecule 3.74356
HBA1 hemoglobin, alpha 1 3.74356
DMRTC1B DMRT-like family C1B 3.74356
SIGLEC9 sialic acid binding Ig-like lectin 9 3.74356
ASB12 ankyrin repeat and SOCS box containing 12 3.74356
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide 3.74356
ASPA aspartoacylase 3.74356
SFXN3 sideroflexin 3 3.74356
FAM221B family with sequence similarity 221, member B 3.74356
POSTN periostin, osteoblast specific factor 3.74356
ACVRL1 activin A receptor type II-like 1 3.74356
AADACL3 arylacetamide deacetylase-like 3 3.74356
MYBPC3 myosin binding protein C, cardiac 3.74356
AGTR1 angiotensin II receptor, type 1 3.74356
LRRD1 leucine-rich repeats and death domain containing 1 3.74356
MAGEB16 melanoma antigen family B16 3.74356
SLC26A9 solute carrier family 26 (anion exchanger), member 9 3.74356
SERPINA10 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10 3.74356
SLC46A2 solute carrier family 46, member 2 3.74356
HEATR9 HEAT repeat containing 9 3.74356
CELF6 CUGBP, Elav-like family member 6 3.74356
NANOS3 nanos homolog 3 (Drosophila) 3.74356
CAMP cathelicidin antimicrobial peptide 3.74356
NEUROG3 neurogenin 3 3.74356
S100A1 S100 calcium binding protein A1 3.74356
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 3.74356
EN2 engrailed homeobox 2 3.74356
SOST sclerostin 3.74356
WFDC11 WAP four-disulfide core domain 11 3.74356
ADAMTS18 ADAM metallopeptidase with thrombospondin type 1 motif, 18 3.74356
AMIGO3 adhesion molecule with Ig-like domain 3 3.74356
R3HDML R3H domain containing-like 3.74356
PITX3 paired-like homeodomain 3 3.74356
GLB1L galactosidase, beta 1-like 3.74356
NLRP9 NLR family, pyrin domain containing 9 3.74356
FAM161B family with sequence similarity 161, member B 3.74356
SLC10A5 solute carrier family 10, member 5 3.74356
NAA11 N(alpha)-acetyltransferase 11, NatA catalytic subunit 3.74356
OXT oxytocin/neurophysin I prepropeptide 3.74356
GALR3 galanin receptor 3 3.74356
OVCH1 ovochymase 1 3.74356
ETV7 ets variant 7 3.74356
OR2B11 olfactory receptor, family 2, subfamily B, member 11 3.74356
CHRNB3 cholinergic receptor, nicotinic, beta 3 (neuronal) 3.74356
THEMIS thymocyte selection associated 3.74356
SLC22A9 solute carrier family 22 (organic anion transporter), member 9 3.74356
STEAP4 STEAP family member 4 3.74356
POPDC2 popeye domain containing 2 3.74356
ENPP6 ectonucleotide pyrophosphatase/phosphodiesterase 6 3.74356
FAM240C family with sequence similarity 240 member C 3.74356
DEPP1 DEPP autophagy regulator 1 3.74356
TMEM275 transmembrane protein 275 3.74356
STYXL2 serine/threonine/tyrosine interacting like 2 3.74356
C3AR1 complement component 3a receptor 1 3.74356
PNLIPRP1 pancreatic lipase-related protein 1 3.74356
SPI1 Spi-1 proto-oncogene 3.74356
TCERG1L transcription elongation regulator 1-like 3.74356
OR6F1 olfactory receptor, family 6, subfamily F, member 1 3.74356
THSD8 thrombospondin type 1 domain containing 8 3.74356
TMEM190 transmembrane protein 190 3.74356
LORICRIN loricrin cornified envelope precursor protein 3.74356
CRACDL CRACD like 3.74356
ADAMTSL4-AS2 ADAMTSL4 antisense RNA 2 3.74356
MINDY4B MINDY family member 4B 3.74356
GLYATL1B glycine-N-acyltransferase like 1B 3.74356
STPG3 sperm-tail PG-rich repeat containing 3 3.74356
TEX46 testis expressed 46 3.74356
GSTT4 glutathione S-transferase theta 4 3.74356
CFAP206 cilia and flagella associated protein 206 3.74356
DEFB131B defensin beta 131B 3.74356
ALKAL1 ALK and LTK ligand 1 3.74356
CIROP ciliated left-right organizer metallopeptidase 3.74356
FAM228A family with sequence similarity 228, member A 3.74356
PNPLA1 patatin-like phospholipase domain containing 1 3.74356
PCDHA2 protocadherin alpha 2 3.74356
RLBP1 retinaldehyde binding protein 1 3.74356
OR2A5 olfactory receptor, family 2, subfamily A, member 5 3.74356
ELAVL4 ELAV like neuron-specific RNA binding protein 4 3.74356
KBTBD13 kelch repeat and BTB (POZ) domain containing 13 3.74356
SLC22A16 solute carrier family 22 (organic cation/carnitine transporter), member 16 3.74356
AKAP3 A kinase (PRKA) anchor protein 3 3.74356
COL19A1 collagen, type XIX, alpha 1 3.74356
COX4I2 cytochrome c oxidase subunit IV isoform 2 (lung) 3.74356
TMPRSS11A transmembrane protease, serine 11A 3.74356
PCDHA3 protocadherin alpha 3 3.74356
TNFRSF14 tumor necrosis factor receptor superfamily, member 14 3.74356
IL1R2 interleukin 1 receptor, type II 3.74356
PGA3 pepsinogen 3, group I (pepsinogen A) 3.74356
SBSN suprabasin 3.74356
S100G S100 calcium binding protein G 3.74356
OR2L2 olfactory receptor, family 2, subfamily L, member 2 3.74356
TPTE transmembrane phosphatase with tensin homology 3.74356
OR2A14 olfactory receptor, family 2, subfamily A, member 14 3.74356
CBLN2 cerebellin 2 precursor 3.74356
IL31RA interleukin 31 receptor A 3.74356
MAG myelin associated glycoprotein 3.74356
FAM187B family with sequence similarity 187, member B 3.74356
RAB7B RAB7B, member RAS oncogene family 3.74356
TAF7L TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 50kDa 3.74356
BCL2L15 BCL2-like 15 3.74356
OR1B1 olfactory receptor, family 1, subfamily B, member 1 (gene/pseudogene) 3.74356
PLGLB2 plasminogen-like B2 3.74356
NUTM2D NUT family member 2D 3.74356
EPO erythropoietin 3.74356
AMER3 APC membrane recruitment protein 3 3.74356
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1 3.74356
BCO1 beta-carotene oxygenase 1 3.74356
THBD thrombomodulin 3.74356
DCSTAMP dendrocyte expressed seven transmembrane protein 3.74356
GH1 growth hormone 1 3.74356
NLRC3 NLR family, CARD domain containing 3 3.74356
GLT6D1 glycosyltransferase 6 domain containing 1 3.74356
TMPPE transmembrane protein with metallophosphoesterase domain 3.74356
EVPLL envoplakin-like 3.74356
ETV3L ets variant 3-like 3.74356
C2CD4B C2 calcium-dependent domain containing 4B 3.74356
PGR progesterone receptor 3.74356
HHATL hedgehog acyltransferase-like 3.74356
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3 3.74356
BAIAP3 BAI1-associated protein 3 3.74356
CLEC4C C-type lectin domain family 4, member C 3.74356
CD53 CD53 molecule 3.74356
CFAP126 cilia and flagella associated protein 126 3.74356
CALML6 calmodulin-like 6 3.74356
WNT2 wingless-type MMTV integration site family member 2 3.74356
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6 3.74356
ZPBP zona pellucida binding protein 3.74356
ODF1 outer dense fiber of sperm tails 1 3.74356
NTSR1 neurotensin receptor 1 (high affinity) 3.74356
RGS11 regulator of G-protein signaling 11 3.74356
APOL6 apolipoprotein L, 6 3.74356
FBXO47 F-box protein 47 3.74356
S100Z S100 calcium binding protein Z 3.74356
ATP6V0D2 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2 3.74356
AGBL4 ATP/GTP binding protein-like 4 3.74356
ART1 ADP-ribosyltransferase 1 3.74356
KLHL6 kelch-like family member 6 3.74356
CASQ2 calsequestrin 2 (cardiac muscle) 3.74356
PCDHAC2 protocadherin alpha subfamily C, 2 3.74356
DLX3 distal-less homeobox 3 3.74356
TGM7 transglutaminase 7 3.74356
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 3.74356
PADI1 peptidyl arginine deiminase, type I 3.74356
PAX6 paired box 6 3.74356
PRH2 proline-rich protein HaeIII subfamily 2 3.74356
S100A14 S100 calcium binding protein A14 3.74356
ADGRD1 adhesion G protein-coupled receptor D1 3.74356
SYNE3 spectrin repeat containing, nuclear envelope family member 3 3.74356
FOXP3 forkhead box P3 3.74356
CPSF4L cleavage and polyadenylation specific factor 4-like 3.74356
GPR12 G protein-coupled receptor 12 3.74356
C20ORF144 chromosome 20 open reading frame 144 3.74356
APOL4 apolipoprotein L, 4 3.74356
CD80 CD80 molecule 3.74356
CD8B CD8b molecule 3.74356
GALNT15 polypeptide N-acetylgalactosaminyltransferase 15 3.74356
PRAP1 proline-rich acidic protein 1 3.74356
RTN4RL1 reticulon 4 receptor-like 1 3.74356
KLK3 kallikrein-related peptidase 3 3.74356
ITGB7 integrin, beta 7 3.74356
TNN tenascin N 3.74356
TF transferrin 3.74356
MMP1 matrix metallopeptidase 1 3.74356
TRAF3IP3 TRAF3 interacting protein 3 3.74356
H2BC13 H2B clustered histone 13 3.66119
RASSF6 Ras association (RalGDS/AF-6) domain family member 6 3.66119
GABRG1 gamma-aminobutyric acid (GABA) A receptor, gamma 1 3.66119
AZIN2 antizyme inhibitor 2 3.66119
ACSL1 acyl-CoA synthetase long-chain family member 1 3.59967
RBM47 RNA binding motif protein 47 3.54423
ARPC3 actin related protein 2/3 complex, subunit 3, 21kDa 3.1514
FUNDC2 FUN14 domain containing 2 3.07512
CCDC13 coiled-coil domain containing 13 2.94715
RHOJ ras homolog family member J 2.94715
CNBD2 cyclic nucleotide binding domain containing 2 2.85128
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26 2.83179
EGFL8 EGF-like-domain, multiple 8 2.79625
H1-0 H1.0 linker histone 2.76997
BOC BOC cell adhesion associated, oncogene regulated 2.76997
PPP1R7 protein phosphatase 1, regulatory subunit 7 2.70423
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) 2.63796
HSD17B3 hydroxysteroid (17-beta) dehydrogenase 3 2.62142
KLB klotho beta 2.62142
PRODH proline dehydrogenase (oxidase) 1 2.62142
TMIE transmembrane inner ear 2.62142
SLC24A5 solute carrier family 24 (sodium/potassium/calcium exchanger), member 5 2.62142
NLRP10 NLR family, pyrin domain containing 10 2.62142
LOC122526780 uncharacterized LOC122526780 2.62142
NRSN1 neurensin 1 2.62142
PSTPIP1 proline-serine-threonine phosphatase interacting protein 1 2.62142
PPARD peroxisome proliferator-activated receptor delta 2.59019
SLC30A9 solute carrier family 30 (zinc transporter), member 9 2.56005
CMTM8 CKLF-like MARVEL transmembrane domain containing 8 2.53732
GEMIN8 gem (nuclear organelle) associated protein 8 2.5282
GGT7 gamma-glutamyltransferase 7 2.4983
RAD9A RAD9 homolog A (S. pombe) 2.49165
CMTM4 CKLF-like MARVEL transmembrane domain containing 4 2.49165
CGN cingulin 2.48918
AMIGO1 adhesion molecule with Ig-like domain 1 2.44535
MYMK myomaker, myoblast fusion factor 2.44535
RNF125 ring finger protein 125, E3 ubiquitin protein ligase 2.42902
THUMPD1 THUMP domain containing 1 2.42112
ENDOG endonuclease G 2.40038
ANXA7 annexin A7 2.38668
NMNAT2 nicotinamide nucleotide adenylyltransferase 2 2.38668
ZFAND6 zinc finger, AN1-type domain 6 2.34245
OR4D1 olfactory receptor, family 4, subfamily D, member 1 2.33872
DCLRE1A DNA cross-link repair 1A 2.33872
IRAG1 inositol 1,4,5-triphosphate receptor associated 1 2.33872
LRPPRC leucine-rich pentatricopeptide repeat containing 2.31774
TMPRSS4 transmembrane protease, serine 4 2.31301
TSNAX translin-associated factor X 2.31301
ITSN1 intersectin 1 (SH3 domain protein) 2.31205
RSPH10B2 radial spoke head 10 homolog B2 (Chlamydomonas) 2.31205
MUC19 mucin 19, oligomeric 2.31205
COBL cordon-bleu WH2 repeat protein 2.29335
NUDT2 nudix (nucleoside diphosphate linked moiety X)-type motif 2 2.27314
MAP3K4 mitogen-activated protein kinase kinase kinase 4 2.261
JMJD6 jumonji domain containing 6 2.25456
TSHZ3 teashirt zinc finger homeobox 3 2.25397
TTPA tocopherol (alpha) transfer protein 2.25397
ZNF880 zinc finger protein 880 2.25169
ERI3 ERI1 exoribonuclease family member 3 2.23731
RTBDN retbindin 2.23057
ME2 malic enzyme 2, NAD(+)-dependent, mitochondrial 2.21939
CDPF1 cysteine-rich, DPF motif domain containing 1 2.21299
ZNF460 zinc finger protein 460 2.21077
UQCRQ ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa 2.19489
CNST consortin, connexin sorting protein 2.19489
PEX10 peroxisomal biogenesis factor 10 2.18512
LYRM2 LYR motif containing 2 2.16124
TMEM120B transmembrane protein 120B 2.15302
EID3 EP300 interacting inhibitor of differentiation 3 2.13901
CUL4A cullin 4A 2.09098
FBXO44 F-box protein 44 2.06518
SRCIN1 SRC kinase signaling inhibitor 1 2.05521
FHIT fragile histidine triad 2.04948
FSCN1 fascin actin-bundling protein 1 2.04467
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 2.04061
DIAPH2 diaphanous-related formin 2 2.03778
ORMDL3 ORMDL sphingolipid biosynthesis regulator 3 2.01795
NUCLEOLIN nucleolin multifunctional protein 2.01762
ICE2 interactor of little elongation complex ELL subunit 2 2.01001
ASRGL1 asparaginase like 1 2.00995
SAP25 Sin3A-associated protein, 25kDa 2.00529
FMNL2 formin-like 2 2.00215
ANKRD13C ankyrin repeat domain 13C 2.00112

decreased expression

Symbol Name Standardized Value
CA1 carbonic anhydrase I -3.74356
PEX12 peroxisomal biogenesis factor 12 -3.74356
OR8D4 olfactory receptor, family 8, subfamily D, member 4 -3.74356
OR2A12 olfactory receptor, family 2, subfamily A, member 12 -3.74356
PDCD1 programmed cell death 1 -3.74356
C1QTNF9 C1q and tumor necrosis factor related protein 9 -3.74356
NGF nerve growth factor (beta polypeptide) -3.74356
EBF2 early B-cell factor 2 -3.74356
LGSN lengsin, lens protein with glutamine synthetase domain -3.74356
GCSAM germinal center-associated, signaling and motility -3.74356
ZNF582 zinc finger protein 582 -3.74356
CLCNKA chloride channel, voltage-sensitive Ka -3.74356
ADAM29 ADAM metallopeptidase domain 29 -3.74356
OLIG1 oligodendrocyte transcription factor 1 -3.74356
SYCE3 synaptonemal complex central element protein 3 -3.74356
HSD3B7 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 -3.74356
CRYGB crystallin, gamma B -3.74356
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 -3.74356
SLC15A5 solute carrier family 15, member 5 -3.74356
TMC3 transmembrane channel-like 3 -3.74356
FAM181B family with sequence similarity 181, member B -3.74356
DUSP15 dual specificity phosphatase 15 -3.74356
EFCAB3 EF-hand calcium binding domain 3 -3.74356
PDF peptide deformylase (mitochondrial) -3.74356
ITGA10 integrin, alpha 10 -3.74356
ODAD1 outer dynein arm docking complex subunit 1 -3.74356
EMP1 epithelial membrane protein 1 -3.74356
NTN5 netrin 5 -3.74356
LY6G6D lymphocyte antigen 6 complex, locus G6D -3.74356
NPBWR1 neuropeptides B/W receptor 1 -3.74356
MS4A15 membrane-spanning 4-domains, subfamily A, member 15 -3.74356
ALX3 ALX homeobox 3 -3.74356
ZMYND15 zinc finger, MYND-type containing 15 -3.74356
KLF5 Kruppel-like factor 5 (intestinal) -3.74356
C1ORF53 chromosome 1 open reading frame 53 -3.69947
RUNDC3B RUN domain containing 3B -3.40204
FTCD formimidoyltransferase cyclodeaminase -3.25245
ANAPC5 anaphase promoting complex subunit 5 -3.23796
CNRIP1 cannabinoid receptor interacting protein 1 -2.99983
CPSF2 cleavage and polyadenylation specific factor 2, 100kDa -2.98337
MOB3C MOB kinase activator 3C -2.97291
UHMK1 U2AF homology motif (UHM) kinase 1 -2.97291
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) -2.94526
TK2 thymidine kinase 2, mitochondrial -2.91073
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A -2.89044
ADGRG5 adhesion G protein-coupled receptor G5 -2.83501
FBH1 F-box DNA helicase 1 -2.83179
CHAMP1 chromosome alignment maintaining phosphoprotein 1 -2.8231
BDH2 3-hydroxybutyrate dehydrogenase, type 2 -2.79414
KCNE3 potassium channel, voltage gated subfamily E regulatory beta subunit 3 -2.78558
TWNK twinkle mtDNA helicase -2.74317
BRCA2 breast cancer 2, early onset -2.74317
NPY5R neuropeptide Y receptor Y5 -2.73934
KCNMB3 potassium channel subfamily M regulatory beta subunit 3 -2.73362
DENND2D DENN/MADD domain containing 2D -2.6933
GSG1 germ cell associated 1 -2.6933
CFAP119 cilia and flagella associated protein 119 -2.6933
HYPK huntingtin interacting protein K -2.6933
BRIX1 BRX1, biogenesis of ribosomes -2.62072
MON1B MON1 secretory trafficking family member B -2.53732
CSNK1G2 casein kinase 1, gamma 2 -2.50825
ASXL3 additional sex combs like transcriptional regulator 3 -2.49421
GTF2A1L general transcription factor IIA, 1-like -2.4797
RPS17 ribosomal protein S17 -2.46645
EIF2D eukaryotic translation initiation factor 2D -2.4578
FBL fibrillarin -2.45164
KIF9 kinesin family member 9 -2.41407
MRPL53 mitochondrial ribosomal protein L53 -2.40554
IGSF22 immunoglobulin superfamily, member 22 -2.40554
TSPAN31 tetraspanin 31 -2.38218
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 -2.36913
IMP3 IMP3, U3 small nucleolar ribonucleoprotein -2.34943
BCL2L2 BCL2-like 2 -2.34936
SF3B1 splicing factor 3b, subunit 1, 155kDa -2.33872
SRRM2 serine/arginine repetitive matrix 2 -2.33872
EPAS1 endothelial PAS domain protein 1 -2.33872
MAT1A methionine adenosyltransferase I, alpha -2.3379
SLC44A4 solute carrier family 44, member 4 -2.31301
FRMD1 FERM domain containing 1 -2.31301
IQCC IQ motif containing C -2.31301
GHRL ghrelin/obestatin prepropeptide -2.31301
UBE2E1 ubiquitin-conjugating enzyme E2E 1 -2.30551
CFAP54 cilia and flagella associated 54 -2.29632
SLC30A7 solute carrier family 30 (zinc transporter), member 7 -2.28475
UBC ubiquitin C -2.28149
CEMIP cell migration inducing protein, hyaluronan binding -2.27971
CDR2L cerebellar degeneration-related protein 2-like -2.2573
GFOD2 glucose-fructose oxidoreductase domain containing 2 -2.25397
LCMT1 leucine carboxyl methyltransferase 1 -2.25397
FAM13A family with sequence similarity 13, member A -2.24778
PTBP3 polypyrimidine tract binding protein 3 -2.24021
TMEM223 transmembrane protein 223 -2.22369
UPRT uracil phosphoribosyltransferase (FUR1) homolog (S. cerevisiae) -2.22369
ADGRF3 adhesion G protein-coupled receptor F3 -2.22321
SGCE sarcoglycan, epsilon -2.20563
SLC29A4 solute carrier family 29 (equilibrative nucleoside transporter), member 4 -2.20392
CARMIL1 capping protein regulator and myosin 1 linker 1 -2.19489
NEURL1 neuralized E3 ubiquitin protein ligase 1 -2.17741
RASSF5 Ras association (RalGDS/AF-6) domain family member 5 -2.17201
RPS19 ribosomal protein S19 -2.16124
PDPK1 3-phosphoinositide dependent protein kinase 1 -2.13901
METTL14 methyltransferase like 14 -2.13479
KIAA0232 KIAA0232 -2.10359
PTPRF protein tyrosine phosphatase, receptor type, F -2.08442
CCDC194 coiled-coil domain containing 194 -2.05021
IFI16 interferon, gamma-inducible protein 16 -2.05021
VARS2 valyl-tRNA synthetase 2, mitochondrial -2.04919
USH1C Usher syndrome 1C (autosomal recessive, severe) -2.04467
ZNF518B zinc finger protein 518B -2.04261
POLR3G polymerase (RNA) III (DNA directed) polypeptide G (32kD) -2.04061
RPS20 ribosomal protein S20 -2.04061
BOD1 biorientation of chromosomes in cell division 1 -2.03798
AGA aspartylglucosaminidase -2.03778
CENPS centromere protein S -2.03469
MMP11 matrix metallopeptidase 11 -2.03392
MID1 midline 1 -2.02774
USP30 ubiquitin specific peptidase 30 -2.02634
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa -2.01762
WSCD1 WSC domain containing 1 -2.01762
CAMSAP1 calmodulin regulated spectrin-associated protein 1 -2.01001
TMEM154 transmembrane protein 154 -2.00554
MCOLN3 mucolipin 3 -2.00215
LIAT1 ligand of ATE1 -2.00215