USP1 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description ubiquitin specific peptidase 1|This gene encodes a member of the ubiquitin-specific processing (UBP) family of proteases that is a deubiquitinating enzyme (DUB) with His and Cys domains. This protein is located in the cytoplasm and cleaves the ubiquitin moiety from ubiquitin-fused precursors and ubiquitinylated proteins. The protein specifically deubiquitinates a protein in the Fanconi anemia (FA) DNA repair pathway. Alternate transcriptional splice variants have been characterized. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 7398)
External Link https://ncbi.nlm.nih.gov/gene/7398
Similar Terms
Downloads & Tools

Genes

498 genes differentially expressed following the USP1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
CD9 CD9 molecule 0.00752907
SPINK1 serine peptidase inhibitor, Kazal type 1 0.00723318
BAMBI BMP and activin membrane-bound inhibitor 0.00706171
IPO13 importin 13 0.00671238
PDE4A phosphodiesterase 4A, cAMP-specific 0.00613912
RGCC regulator of cell cycle 0.00607154
AKR1C3 aldo-keto reductase family 1, member C3 0.00596351
AMIGO2 adhesion molecule with Ig-like domain 2 0.00587965
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 0.00585169
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3 0.00551975
PRR7 proline rich 7 (synaptic) 0.00541581
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C 0.00535564
METRN meteorin, glial cell differentiation regulator 0.00529828
JCHAIN joining chain of multimeric IgA and IgM 0.00519926
NPEPL1 aminopeptidase-like 1 0.00509716
GRB7 growth factor receptor-bound protein 7 0.00497154
HOMER3 homer scaffolding protein 3 0.00495138
NPRL2 nitrogen permease regulator-like 2 (S. cerevisiae) 0.00488187
LYN LYN proto-oncogene, Src family tyrosine kinase 0.00482434
TRAF5 TNF receptor-associated factor 5 0.00480244
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) 0.00479818
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 0.00478515
PTK2B protein tyrosine kinase 2 beta 0.00470574
FXYD2 FXYD domain containing ion transport regulator 2 0.00468149
C3 complement component 3 0.00465312
PCNA proliferating cell nuclear antigen 0.00463787
PPP1R3C protein phosphatase 1, regulatory subunit 3C 0.00463355
MYB v-myb avian myeloblastosis viral oncogene homolog 0.00463118
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8 0.00456921
EREG epiregulin 0.00454859
TUBB6 tubulin, beta 6 class V 0.00454702
XIC X chromosome inactivation center 0.00447058
IER5 immediate early response 5 0.00446387
SIRPA signal-regulatory protein alpha 0.00441146
KRT6A keratin 6A, type II 0.0044049
CFD complement factor D (adipsin) 0.00440393
AREG amphiregulin 0.00435978
HTRA1 HtrA serine peptidase 1 0.00434525
CDK5RAP3 CDK5 regulatory subunit associated protein 3 0.0043191
PLN phospholamban 0.00429406
CDK14 cyclin-dependent kinase 14 0.00424831
TPM2 tropomyosin 2 (beta) 0.00424567
SIK1 salt-inducible kinase 1 0.00424091
SHB Src homology 2 domain containing adaptor protein B 0.00421577
PKD2 polycystic kidney disease 2 (autosomal dominant) 0.00421041
KIAA0930 KIAA0930 0.00414264
THBS2 thrombospondin 2 0.00413808
ALOX5 arachidonate 5-lipoxygenase 0.00413456
MICALL1 MICAL-like 1 0.00412176
PXN paxillin 0.00409374
PODXL podocalyxin-like 0.00409131
YBX3 Y box binding protein 3 0.00407982
JAG1 jagged 1 0.00407829
CYB5A cytochrome b5 type A (microsomal) 0.00405057
GAS6 growth arrest-specific 6 0.0040466
ALOX5AP arachidonate 5-lipoxygenase-activating protein 0.00401699
KANK1 KN motif and ankyrin repeat domains 1 0.00399251
LYPLA1 lysophospholipase I 0.00399244
SPON2 spondin 2, extracellular matrix protein 0.00393846
RNF128 ring finger protein 128, E3 ubiquitin protein ligase 0.00389908
FLNC filamin C, gamma 0.00387576
CLDN10 claudin 10 0.00386663
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32) 0.00385399
PERP PERP, TP53 apoptosis effector 0.00384757
ADAM9 ADAM metallopeptidase domain 9 0.00384607
GPX1 glutathione peroxidase 1 0.00383607
G0S2 G0/G1 switch 2 0.00381825
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) 0.00377691
ACTC1 actin, alpha, cardiac muscle 1 0.00377437
USP32P2 ubiquitin specific peptidase 32 pseudogene 2 0.00376217
BHLHE41 basic helix-loop-helix family, member e41 0.0037448
MAOA monoamine oxidase A 0.00373993
PYCARD PYD and CARD domain containing 0.00373958
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa 0.00373082
POLR1D polymerase (RNA) I polypeptide D, 16kDa 0.00372292
SNAI2 snail family zinc finger 2 0.00371357
SCAF4 SR-related CTD-associated factor 4 0.00370354
TAGLN transgelin 0.00369532
TMEM176A transmembrane protein 176A 0.00367774
MZB1 marginal zone B and B1 cell-specific protein 0.00367534
ACTG2 actin, gamma 2, smooth muscle, enteric 0.00366995
TOB1 transducer of ERBB2, 1 0.00366682
PILRB paired immunoglobin-like type 2 receptor beta 0.0036645
REX1BD required for excision 1-B domain containing 0.00364502
TLN1 talin 1 0.0036271
RASGRP3 RAS guanyl releasing protein 3 (calcium and DAG-regulated) 0.00361208
FHOD3 formin homology 2 domain containing 3 0.00360342
NDUFA5 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 0.00359953
FBP1 fructose-1,6-bisphosphatase 1 0.00358723
PLTP phospholipid transfer protein 0.00358345
FERMT1 fermitin family member 1 0.00358103
MTCL1 microtubule crosslinking factor 1 0.0035799
SNCA synuclein, alpha (non A4 component of amyloid precursor) 0.0035755
EHD2 EH-domain containing 2 0.00357177
AGRN agrin 0.00353342
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 0.00352015
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1 0.00350695
GPX2 glutathione peroxidase 2 0.00347282
SLC26A6 solute carrier family 26 (anion exchanger), member 6 0.00343728
TGFA transforming growth factor, alpha 0.00343485
APOC1 apolipoprotein C-I 0.00342899
VCAN versican 0.00342694
CELSR1 cadherin, EGF LAG seven-pass G-type receptor 1 0.0034238
DES desmin 0.00341429
ZNF589 zinc finger protein 589 0.00340594
THAP11 THAP domain containing 11 0.00339558
MET MET proto-oncogene, receptor tyrosine kinase 0.00339262
FSCN1 fascin actin-bundling protein 1 0.00338678
GREM1 gremlin 1, DAN family BMP antagonist 0.00338313
CPSF4 cleavage and polyadenylation specific factor 4, 30kDa 0.003378
POLR2J polymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa 0.0033756
COG2 component of oligomeric golgi complex 2 0.00337232
FKBP11 FK506 binding protein 11, 19 kDa 0.00336073
SLC4A2 solute carrier family 4 (anion exchanger), member 2 0.00335387
DOCK4 dedicator of cytokinesis 4 0.00334946
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) 0.00334447
PDLIM7 PDZ and LIM domain 7 (enigma) 0.00333365
PTPRO protein tyrosine phosphatase, receptor type, O 0.00332895
FABP4 fatty acid binding protein 4, adipocyte 0.00331933
TPSAB1 tryptase alpha/beta 1 0.00331319
TGM2 transglutaminase 2 0.00330742
DMPK dystrophia myotonica-protein kinase 0.00330718
ATP2B2 ATPase, Ca++ transporting, plasma membrane 2 0.00330442
POU2AF1 POU class 2 associating factor 1 0.00328635
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) 0.003281
DIPK1A divergent protein kinase domain 1A 0.00326674
PFKM phosphofructokinase, muscle 0.00326207
COA3 cytochrome c oxidase assembly factor 3 0.0032582
TMEM63A transmembrane protein 63A 0.00325349
ANXA4 annexin A4 0.00324684
UGDH UDP-glucose 6-dehydrogenase 0.00323819
CST1 cystatin SN 0.00322298
DPYSL2 dihydropyrimidinase-like 2 0.00322092
KRT17 keratin 17, type I 0.00321526
SMAD7 SMAD family member 7 0.00321042
PLPP2 phospholipid phosphatase 2 0.00320137
LAMC2 laminin, gamma 2 0.00320028
HYOU1 hypoxia up-regulated 1 0.00318191
CXCL5 chemokine (C-X-C motif) ligand 5 0.00316142
OLIG2 oligodendrocyte lineage transcription factor 2 0.003158
TARBP1 TAR (HIV-1) RNA binding protein 1 0.00315745
NRIP1 nuclear receptor interacting protein 1 0.00315715
SLC38A6 solute carrier family 38, member 6 0.0031564
APOD apolipoprotein D 0.0031504
PRDX3 peroxiredoxin 3 0.00314731
GSDME gasdermin E 0.00313164
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) 0.00312377
LRFN4 leucine rich repeat and fibronectin type III domain containing 4 0.00312175
NDUFS7 NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase) 0.00310159
TNFRSF17 tumor necrosis factor receptor superfamily, member 17 0.00310013
VPS72 vacuolar protein sorting 72 homolog (S. cerevisiae) 0.00309735
ADCY7 adenylate cyclase 7 0.00308092
COPS7A COP9 signalosome subunit 7A 0.00307654
DENND4B DENN/MADD domain containing 4B 0.00307649
PDLIM3 PDZ and LIM domain 3 0.00306451
TIMM13 translocase of inner mitochondrial membrane 13 homolog (yeast) 0.00306069
CPA3 carboxypeptidase A3 (mast cell) 0.0030494
THOC7 THO complex 7 0.00304023
PLXNA1 plexin A1 0.00303761
MME membrane metallo-endopeptidase 0.00303188
S100A2 S100 calcium binding protein A2 0.00303002
UPK1B uroplakin 1B 0.00302984
RIN2 Ras and Rab interactor 2 0.00302865
TP53I3 tumor protein p53 inducible protein 3 0.00302622
PRPF4B pre-mRNA processing factor 4B 0.0030243
MYH11 myosin, heavy chain 11, smooth muscle 0.003018
CD52 CD52 molecule 0.0030171
ATP5MF ATP synthase membrane subunit f 0.0030112
ADA adenosine deaminase 0.00300947
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14 0.00300374
TRMT61B tRNA methyltransferase 61B 0.0030025
ATP5F1D ATP synthase F1 subunit delta 0.00298643
FGB fibrinogen beta chain 0.00297915
MED14 mediator complex subunit 14 0.00297439
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2 0.00296314
GPR87 G protein-coupled receptor 87 0.00296242
PUS7 pseudouridylate synthase 7 (putative) 0.00295105
GSDMB gasdermin B 0.00292887
NCF2 neutrophil cytosolic factor 2 0.00292162
CD86 CD86 molecule 0.00291572
GUSBP3 glucuronidase, beta pseudogene 3 0.00291495
IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2 0.00290438
TRIP6 thyroid hormone receptor interactor 6 0.00289627
ACADVL acyl-CoA dehydrogenase, very long chain 0.00289286
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 0.0028819
TSPOAP1 TSPO associated protein 1 0.00288146
FBLN2 fibulin 2 0.00288089
MAZ MYC-associated zinc finger protein (purine-binding transcription factor) 0.00287638
CAV1 caveolin 1, caveolae protein, 22kDa 0.00287224
TRIO trio Rho guanine nucleotide exchange factor 0.00286787
FTH1 ferritin, heavy polypeptide 1 0.00285945
KCTD12 potassium channel tetramerization domain containing 12 0.00285527
NPIPB3 nuclear pore complex interacting protein family, member B3 0.00284999
ORAI3 ORAI calcium release-activated calcium modulator 3 0.00284362
FGR FGR proto-oncogene, Src family tyrosine kinase 0.00284182
TSPAN12 tetraspanin 12 0.00284031
LSM7 LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.00283582
ANTKMT adenine nucleotide translocase lysine methyltransferase 0.00283327
NEIL1 nei endonuclease VIII-like 1 (E. coli) 0.00283261
CTSH cathepsin H 0.00283206
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2 0.00283181
PPP1R14B protein phosphatase 1, regulatory (inhibitor) subunit 14B 0.00283159
CPOX coproporphyrinogen oxidase 0.00282655
MFAP5 microfibrillar associated protein 5 0.00282625
ADARB1 adenosine deaminase, RNA-specific, B1 0.0028233
FLNA filamin A, alpha 0.00281971
DVL3 dishevelled segment polarity protein 3 0.00281621
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) 0.00281464
DDIT3 DNA-damage-inducible transcript 3 0.0028119
FAM193B family with sequence similarity 193, member B 0.00281135
ATOX1 antioxidant 1 copper chaperone 0.00281129
ACSL4 acyl-CoA synthetase long-chain family member 4 0.00281044
GPNMB glycoprotein (transmembrane) nmb 0.00280981
NPAS2 neuronal PAS domain protein 2 0.00280378
TPST2 tyrosylprotein sulfotransferase 2 0.00280354
CCDC51 coiled-coil domain containing 51 0.00280121
SCAND1 SCAN domain containing 1 0.0027992
RBM8A RNA binding motif protein 8A 0.00279687
TGFB1 transforming growth factor, beta 1 0.0027941
TPI1 triosephosphate isomerase 1 0.00279225
PLEKHJ1 pleckstrin homology domain containing, family J member 1 0.00278489
WSB1 WD repeat and SOCS box containing 1 0.00277808
PLXNB1 plexin B1 0.00277806
ZNF277 zinc finger protein 277 0.00277758
TCF4 transcription factor 4 0.0027727
DKK3 dickkopf WNT signaling pathway inhibitor 3 0.00277036
SATB2 SATB homeobox 2 0.00276683
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 0.00276196
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1 0.00275808
SCD stearoyl-CoA desaturase (delta-9-desaturase) 0.00275733
HCFC1R1 host cell factor C1 regulator 1 (XPO1 dependent) 0.00275449
UBA3 ubiquitin-like modifier activating enzyme 3 0.00274967
ATP5ME ATP synthase membrane subunit e 0.00274556
PLS1 plastin 1 0.0027407
CDH2 cadherin 2, type 1, N-cadherin (neuronal) 0.0027404
NME1 NME/NM23 nucleoside diphosphate kinase 1 0.00273911
COL7A1 collagen, type VII, alpha 1 0.00273412
ENGASE endo-beta-N-acetylglucosaminidase 0.00273068
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3 0.00272898
GALNT10 polypeptide N-acetylgalactosaminyltransferase 10 0.00272601
ADORA2B adenosine A2b receptor 0.00272525
PNPLA6 patatin-like phospholipase domain containing 6 0.00272448
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit) 0.00272255
EXT1 exostosin glycosyltransferase 1 0.00272144
FAM3C family with sequence similarity 3, member C 0.00271852
MED22 mediator complex subunit 22 0.00270735
BCL2L1 BCL2-like 1 0.00269832
NBEAL2 neurobeachin-like 2 0.00269418

decreased expression

Symbol Name Standardized Value
USP1 ubiquitin specific peptidase 1 -0.0112818
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) -0.00738569
GPC3 glypican 3 -0.00712338
TSPAN13 tetraspanin 13 -0.00704406
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein -0.00693775
GPM6B glycoprotein M6B -0.00668058
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) -0.00636253
REEP1 receptor accessory protein 1 -0.00614644
SEPP1 selenoprotein P, plasma, 1 -0.00612294
NR2F2 nuclear receptor subfamily 2, group F, member 2 -0.00586607
NUPR1 nuclear protein, transcriptional regulator, 1 -0.00575037
CLU clusterin -0.0057461
CALCA calcitonin-related polypeptide alpha -0.00570289
ARID4A AT rich interactive domain 4A (RBP1-like) -0.00563576
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -0.0055982
CD99 CD99 molecule -0.00556198
GBP1 guanylate binding protein 1, interferon-inducible -0.00555816
PEG3 paternally expressed 3 -0.00548698
AZGP1 alpha-2-glycoprotein 1, zinc-binding -0.0054557
ASS1 argininosuccinate synthase 1 -0.00543874
ATP9A ATPase, class II, type 9A -0.00542529
SFRP1 secreted frizzled-related protein 1 -0.00531099
IL6ST interleukin 6 signal transducer -0.00527784
WLS wntless Wnt ligand secretion mediator -0.00527431
NPR3 natriuretic peptide receptor 3 -0.00527082
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2 -0.00525875
NPY1R neuropeptide Y receptor Y1 -0.00520098
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein) -0.00519005
PDZD2 PDZ domain containing 2 -0.00517794
IFITM1 interferon induced transmembrane protein 1 -0.00515561
MAL mal, T-cell differentiation protein -0.00508644
GCH1 GTP cyclohydrolase 1 -0.00508356
PENK proenkephalin -0.00506792
ACP3 acid phosphatase 3 -0.0050518
IFI44L interferon-induced protein 44-like -0.00502381
TMSB15A thymosin beta 15a -0.00498149
HOXC6 homeobox C6 -0.00496401
PROM1 prominin 1 -0.00496072
NEFH neurofilament, heavy polypeptide -0.00492486
RARRES1 retinoic acid receptor responder (tazarotene induced) 1 -0.00489507
BTG3 BTG family, member 3 -0.00486979
EGR3 early growth response 3 -0.00486619
SORT1 sortilin 1 -0.00485152
ERAP2 endoplasmic reticulum aminopeptidase 2 -0.00482159
LGALS13 lectin, galactoside-binding, soluble, 13 -0.00480453
TGFBR3 transforming growth factor, beta receptor III -0.00480356
ALDH1A2 aldehyde dehydrogenase 1 family, member A2 -0.00477543
CAPZB capping protein (actin filament) muscle Z-line, beta -0.00475798
RBBP4 retinoblastoma binding protein 4 -0.00474872
RAD23B RAD23 homolog B (S. cerevisiae) -0.00473919
PRPH peripherin -0.00473551
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8 -0.00471146
MATN2 matrilin 2 -0.00466374
IFI44 interferon-induced protein 44 -0.00461041
GPX3 glutathione peroxidase 3 -0.00456662
CTH cystathionine gamma-lyase -0.00456421
GPX7 glutathione peroxidase 7 -0.00454782
GNAS GNAS complex locus -0.004546
CPE carboxypeptidase E -0.00453673
TSPAN8 tetraspanin 8 -0.00453287
F2RL1 coagulation factor II (thrombin) receptor-like 1 -0.00450072
RNF144A ring finger protein 144A -0.00444126
PRKACB protein kinase, cAMP-dependent, catalytic, beta -0.00440624
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 -0.00440518
ATF3 activating transcription factor 3 -0.00434318
ADGRG2 adhesion G protein-coupled receptor G2 -0.00433959
TFDP2 transcription factor Dp-2 (E2F dimerization partner 2) -0.0042692
EMP2 epithelial membrane protein 2 -0.00426167
TSPYL5 TSPY-like 5 -0.0042472
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide -0.00422941
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein -0.00422811
EPCAM epithelial cell adhesion molecule -0.00420244
ANXA3 annexin A3 -0.00420001
PSAT1 phosphoserine aminotransferase 1 -0.00419334
BST2 bone marrow stromal cell antigen 2 -0.00418999
TENT5A terminal nucleotidyltransferase 5A -0.00418417
SMARCA1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 -0.00416827
MX1 MX dynamin-like GTPase 1 -0.00416813
S100A7 S100 calcium binding protein A7 -0.00411104
RHOBTB3 Rho-related BTB domain containing 3 -0.00410904
FAM171A1 family with sequence similarity 171, member A1 -0.00410678
TBX3 T-box 3 -0.00410432
FCGBP Fc fragment of IgG binding protein -0.00410089
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 -0.00407922
RSAD2 radical S-adenosyl methionine domain containing 2 -0.00407774
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9 -0.00407097
FKBP5 FK506 binding protein 5 -0.00405849
U2AF1 U2 small nuclear RNA auxiliary factor 1 -0.00403917
OLFM1 olfactomedin 1 -0.00400515
PCSK1 proprotein convertase subtilisin/kexin type 1 -0.00399851
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2 -0.00399277
KRT81 keratin 81, type II -0.00397064
MGP matrix Gla protein -0.00396629
IFI6 interferon, alpha-inducible protein 6 -0.003961
SPRED2 sprouty-related, EVH1 domain containing 2 -0.00395471
USP18 ubiquitin specific peptidase 18 -0.00393859
CDC20 cell division cycle 20 -0.00393699
DCN decorin -0.00393555
HDAC1 histone deacetylase 1 -0.00390419
GLO1 glyoxalase I -0.00389202
IQGAP2 IQ motif containing GTPase activating protein 2 -0.00388249
ERGIC2 ERGIC and golgi 2 -0.00388017
PNMA1 paraneoplastic Ma antigen 1 -0.00387815
AKIRIN1 akirin 1 -0.00385679
MYO1C myosin IC -0.00384928
BBX bobby sox homolog (Drosophila) -0.00383969
USP11 ubiquitin specific peptidase 11 -0.00383694
YAP1 Yes-associated protein 1 -0.0038231
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5 -0.00382135
ADCY3 adenylate cyclase 3 -0.00381144
KLK7 kallikrein-related peptidase 7 -0.00379274
KLK5 kallikrein-related peptidase 5 -0.0037784
DNM1L dynamin 1-like -0.00373577
GMDS GDP-mannose 4,6-dehydratase -0.00372844
SLIT2 slit homolog 2 (Drosophila) -0.00372279
NAB1 NGFI-A binding protein 1 (EGR1 binding protein 1) -0.00371837
C2CD2 C2 calcium-dependent domain containing 2 -0.00370132
TRH thyrotropin-releasing hormone -0.00369643
CD34 CD34 molecule -0.00368665
ATAD2 ATPase family, AAA domain containing 2 -0.00367367
SRSF4 serine/arginine-rich splicing factor 4 -0.00367195
CALML5 calmodulin-like 5 -0.00365664
DAXX death-domain associated protein -0.00365644
NELL2 NEL-like 2 (chicken) -0.00364948
SSX2IP synovial sarcoma, X breakpoint 2 interacting protein -0.00363293
BANK1 B-cell scaffold protein with ankyrin repeats 1 -0.00363003
SERBP1 SERPINE1 mRNA binding protein 1 -0.00361966
RCAN1 regulator of calcineurin 1 -0.00359885
KIFAP3 kinesin-associated protein 3 -0.00359197
LMO2 LIM domain only 2 (rhombotin-like 1) -0.00358011
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa -0.00356993
DHTKD1 dehydrogenase E1 and transketolase domain containing 1 -0.00356548
TACSTD2 tumor-associated calcium signal transducer 2 -0.00355713
APOA1 apolipoprotein A-I -0.00354795
NR4A1 nuclear receptor subfamily 4, group A, member 1 -0.00353696
CLCC1 chloride channel CLIC-like 1 -0.00352589
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) -0.00351713
YES1 YES proto-oncogene 1, Src family tyrosine kinase -0.00351657
DNASE1L3 deoxyribonuclease I-like 3 -0.00351386
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein -0.00350238
ISLR immunoglobulin superfamily containing leucine-rich repeat -0.00348855
UBE2I ubiquitin-conjugating enzyme E2I -0.00347872
DIRAS3 DIRAS family, GTP-binding RAS-like 3 -0.00346332
LXN latexin -0.00346284
CPVL carboxypeptidase, vitellogenic-like -0.0034621
IFITM3 interferon induced transmembrane protein 3 -0.00345913
CAST calpastatin -0.00345895
ACSS3 acyl-CoA synthetase short-chain family member 3 -0.00345622
ABAT 4-aminobutyrate aminotransferase -0.00345291
STMN2 stathmin 2 -0.00344284
ASH2L ash2 (absent, small, or homeotic)-like (Drosophila) -0.00343715
GPR171 G protein-coupled receptor 171 -0.00343219
MALL mal, T-cell differentiation protein-like -0.00342792
CDC42EP4 CDC42 effector protein (Rho GTPase binding) 4 -0.00342773
KAZN kazrin, periplakin interacting protein -0.0034216
SARS1 seryl-tRNA synthetase 1 -0.00341051
SPINK4 serine peptidase inhibitor, Kazal type 4 -0.00339692
LPIN1 lipin 1 -0.00339047
CYP39A1 cytochrome P450, family 39, subfamily A, polypeptide 1 -0.00338925
GSN gelsolin -0.00338466
PRSS8 protease, serine, 8 -0.00338402
MT1M metallothionein 1M -0.00338388
PTCH1 patched 1 -0.0033833
FUCA1 fucosidase, alpha-L- 1, tissue -0.00337565
ISG20 interferon stimulated exonuclease gene 20kDa -0.00334633
LTF lactotransferrin -0.00334229
NRN1 neuritin 1 -0.00333771
IFI27 interferon, alpha-inducible protein 27 -0.0033358
GABRP gamma-aminobutyric acid (GABA) A receptor, pi -0.00332483
C4BPB complement component 4 binding protein, beta -0.00332165
OLFML2A olfactomedin-like 2A -0.00331247
ARG2 arginase 2 -0.00329774
C21ORF91 chromosome 21 open reading frame 91 -0.00329476
RTP4 receptor (chemosensory) transporter protein 4 -0.00329242
ISL1 ISL LIM homeobox 1 -0.00329151
EPB41L4B erythrocyte membrane protein band 4.1 like 4B -0.00326891
PTBP3 polypyrimidine tract binding protein 3 -0.00325671
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 -0.00325481
ARHGAP15 Rho GTPase activating protein 15 -0.00324953
ETV1 ets variant 1 -0.00324762
CALCB calcitonin-related polypeptide beta -0.00324204
IGFBP5 insulin-like growth factor binding protein 5 -0.00323858
AKAP12 A kinase (PRKA) anchor protein 12 -0.00322843
FRZB frizzled-related protein -0.00322446
HSPB11 heat shock protein family B (small), member 11 -0.00322376
EIF5A eukaryotic translation initiation factor 5A -0.00321686
RNF138 ring finger protein 138, E3 ubiquitin protein ligase -0.00321293
CREM cAMP responsive element modulator -0.00321248
XBP1 X-box binding protein 1 -0.00320971
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 -0.00320561
SRRM1 serine/arginine repetitive matrix 1 -0.00320249
S100P S100 calcium binding protein P -0.00319779
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3 -0.00319218
NHS Nance-Horan syndrome (congenital cataracts and dental anomalies) -0.00319174
GSTM3 glutathione S-transferase mu 3 (brain) -0.00318678
FAR2 fatty acyl CoA reductase 2 -0.00318434
ZZZ3 zinc finger, ZZ-type containing 3 -0.00318289
PTTG1IP pituitary tumor-transforming 1 interacting protein -0.00318256
SPINT2 serine peptidase inhibitor, Kunitz type, 2 -0.00317511
NAV3 neuron navigator 3 -0.00316626
PEBP1 phosphatidylethanolamine binding protein 1 -0.00315138
PHACTR2 phosphatase and actin regulator 2 -0.00315023
MOCOS molybdenum cofactor sulfurase -0.00315018
USP33 ubiquitin specific peptidase 33 -0.00314621
CDS1 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1 -0.00313289
IER2 immediate early response 2 -0.00312642
MAPK14 mitogen-activated protein kinase 14 -0.00312347
AP2B1 adaptor-related protein complex 2, beta 1 subunit -0.0031222
PEF1 penta-EF-hand domain containing 1 -0.00311859
CCR7 chemokine (C-C motif) receptor 7 -0.00311527
DEPDC1 DEP domain containing 1 -0.00311277
MDFIC MyoD family inhibitor domain containing -0.00311011
CLIC3 chloride intracellular channel 3 -0.00310827
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) -0.00310586
LANCL2 LanC lantibiotic synthetase component C-like 2 (bacterial) -0.00310141
KLF6 Kruppel-like factor 6 -0.00310133
SLC16A4 solute carrier family 16, member 4 -0.00309697
CLDN3 claudin 3 -0.0030917
PIGK phosphatidylinositol glycan anchor biosynthesis, class K -0.00309121
PTGER3 prostaglandin E receptor 3 (subtype EP3) -0.00308602
PLPP3 phospholipid phosphatase 3 -0.00307753
CDC42 cell division cycle 42 -0.00307576
SLC26A3 solute carrier family 26 (anion exchanger), member 3 -0.00306775
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) -0.00306733
ADD3 adducin 3 (gamma) -0.00306409
FMR1 fragile X mental retardation 1 -0.00306245
LEPROT leptin receptor overlapping transcript -0.00306221
HACD3 3-hydroxyacyl-CoA dehydratase 3 -0.00304993
MAN1A1 mannosidase, alpha, class 1A, member 1 -0.00304862
C1ORF115 chromosome 1 open reading frame 115 -0.00304799
ALDH1A3 aldehyde dehydrogenase 1 family, member A3 -0.00304795
MARCKSL1 MARCKS-like 1 -0.00304083
SS18 synovial sarcoma translocation, chromosome 18 -0.00303961
SARAF store-operated calcium entry-associated regulatory factor -0.00303692
MLF1 myeloid leukemia factor 1 -0.00303654
ZFP36L1 ZFP36 ring finger protein-like 1 -0.00303112
PEX3 peroxisomal biogenesis factor 3 -0.00303076
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 -0.00303042
KIF1B kinesin family member 1B -0.00302409
ABHD4 abhydrolase domain containing 4 -0.00302208
LEPR leptin receptor -0.00302162
WASF2 WAS protein family, member 2 -0.00301632
S100A8 S100 calcium binding protein A8 -0.00301529
ECHDC2 enoyl CoA hydratase domain containing 2 -0.00301067
MAGOH mago-nashi homolog, proliferation-associated (Drosophila) -0.00300714
UBE2E1 ubiquitin-conjugating enzyme E2E 1 -0.00300523
CFLAR CASP8 and FADD-like apoptosis regulator -0.003003
FZD7 frizzled class receptor 7 -0.00300121
CHPT1 choline phosphotransferase 1 -0.00300003
CHODL chondrolectin -0.00299591