USP1 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description ubiquitin specific peptidase 1|This gene encodes a member of the ubiquitin-specific processing (UBP) family of proteases that is a deubiquitinating enzyme (DUB) with His and Cys domains. This protein is located in the cytoplasm and cleaves the ubiquitin moiety from ubiquitin-fused precursors and ubiquitinylated proteins. The protein specifically deubiquitinates a protein in the Fanconi anemia (FA) DNA repair pathway. Alternate transcriptional splice variants have been characterized. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 7398)
External Link http://www.ncbi.nlm.nih.gov/gene/7398
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Genes

110 interacting proteins for USP1 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
AHCYL1 adenosylhomocysteinase-like 1
AHCYL2 adenosylhomocysteinase-like 2
ALDH16A1 aldehyde dehydrogenase 16 family, member A1
AP3M1 adaptor-related protein complex 3, mu 1 subunit
ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10
ATAD5 ATPase family, AAA domain containing 5
BCR breakpoint cluster region
BOP1 block of proliferation 1
C11ORF58 chromosome 11 open reading frame 58
CALML3 calmodulin-like 3
CALML5 calmodulin-like 5
CDK1 cyclin-dependent kinase 1
CRTAP cartilage associated protein
CSE1L CSE1 chromosome segregation 1-like (yeast)
CSNK2A1 casein kinase 2, alpha 1 polypeptide
CSNK2A2 casein kinase 2, alpha prime polypeptide
CSNK2B casein kinase 2, beta polypeptide
CTNND1 catenin (cadherin-associated protein), delta 1
CUL4B cullin 4B
DKC1 dyskeratosis congenita 1, dyskerin
DMWD dystrophia myotonica, WD repeat containing
DSC1 desmocollin 1
DSG1 desmoglein 1
DTX3 deltex 3, E3 ubiquitin ligase
E2F1 E2F transcription factor 1
EIF3A eukaryotic translation initiation factor 3, subunit A
EIF3H eukaryotic translation initiation factor 3, subunit H
EZR ezrin
FAM122B family with sequence similarity 122B
FANCD2 Fanconi anemia, complementation group D2
FANCI Fanconi anemia, complementation group I
FKBP5 FK506 binding protein 5
FLG filaggrin
GPN1 GPN-loop GTPase 1
GPN3 GPN-loop GTPase 3
HNF4A hepatocyte nuclear factor 4, alpha
HSPB1 heat shock 27kDa protein 1
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
IWS1 IWS1 homolog (S. cerevisiae)
JUP junction plakoglobin
KDM4A lysine (K)-specific demethylase 4A
KPNA1 karyopherin alpha 1 (importin alpha 5)
KRT17 keratin 17, type I
KRT4 keratin 4, type II
LGALS7B lectin, galactoside-binding, soluble, 7B
LYZ lysozyme
MAX MYC associated factor X
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYCBP2 MYC binding protein 2, E3 ubiquitin protein ligase
MYH9 myosin, heavy chain 9, non-muscle
NAF1 nuclear assembly factor 1 ribonucleoprotein
NELFE negative elongation factor complex member E
NHP2 NHP2 ribonucleoprotein
NOP10 NOP10 ribonucleoprotein
P3H1 prolyl 3-hydroxylase 1
PCNA proliferating cell nuclear antigen
PHF7 PHD finger protein 7
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1
PHLPP2 PH domain and leucine rich repeat protein phosphatase 2
PKP1 plakophilin 1
POLR2G polymerase (RNA) II (DNA directed) polypeptide G
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa
PPIB peptidylprolyl isomerase B (cyclophilin B)
PPP1R9A protein phosphatase 1, regulatory subunit 9A
PPP1R9B protein phosphatase 1, regulatory subunit 9B
PPP5C protein phosphatase 5, catalytic subunit
PSME3 proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)
RAD51AP1 RAD51 associated protein 1
RBM15 RNA binding motif protein 15
RDX radixin
RPS27A ribosomal protein S27a
SCRIB scribbled planar cell polarity protein
SET SET nuclear proto-oncogene
SHQ1 SHQ1, H/ACA ribonucleoprotein assembly factor
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
SNX27 sorting nexin family member 27
STK11 serine/threonine kinase 11
SUGT1 SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae)
SUMO2 small ubiquitin-like modifier 2
SUPT6H suppressor of Ty 6 homolog (S. cerevisiae)
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
TAGLN2 transgelin 2
TARBP1 TAR (HIV-1) RNA binding protein 1
TCOF1 Treacher Collins-Franceschetti syndrome 1
TP53 tumor protein p53
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRIM46 tripartite motif containing 46
TRMT11 tRNA methyltransferase 11 homolog (S. cerevisiae)
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1
UBB ubiquitin B
UBC ubiquitin C
UBE2A ubiquitin-conjugating enzyme E2A
UBR5 ubiquitin protein ligase E3 component n-recognin 5
UNC45A unc-45 homolog A (C. elegans)
USP12 ubiquitin specific peptidase 12
USP4 ubiquitin specific peptidase 4 (proto-oncogene)
USP46 ubiquitin specific peptidase 46
VAT1 vesicle amine transport 1
VPS26A vacuolar protein sorting 26 homolog A (S. pombe)
VPS36 vacuolar protein sorting 36 homolog (S. cerevisiae)
WDR20 WD repeat domain 20
WDR48 WD repeat domain 48
WDR5 WD repeat domain 5
WDR70 WD repeat domain 70
WRN Werner syndrome, RecQ helicase-like
YLPM1 YLP motif containing 1
ZBTB2 zinc finger and BTB domain containing 2
ZBTB33 zinc finger and BTB domain containing 33
ZNF639 zinc finger protein 639