USP11 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description ubiquitin specific peptidase 11|Protein ubiquitination controls many intracellular processes, including cell cycle progression, transcriptional activation, and signal transduction. This dynamic process, involving ubiquitin conjugating enzymes and deubiquitinating enzymes, adds and removes ubiquitin. Deubiquitinating enzymes are cysteine proteases that specifically cleave ubiquitin from ubiquitin-conjugated protein substrates. This gene encodes a deubiquitinating enzyme which lies in a gene cluster on chromosome Xp11.23 [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 8237)
External Link http://www.ncbi.nlm.nih.gov/gene/8237
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Genes

423 interacting proteins for USP11 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
ABCD3 ATP-binding cassette, sub-family D (ALD), member 3
AFF4 AF4/FMR2 family, member 4
AGO1 argonaute RISC catalytic component 1
AGO3 argonaute RISC catalytic component 3
AHCYL1 adenosylhomocysteinase-like 1
AHCYL2 adenosylhomocysteinase-like 2
AKAP11 A kinase (PRKA) anchor protein 11
ALYREF Aly/REF export factor
AMOT angiomotin
ANP32A acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
ANP32B acidic (leucine-rich) nuclear phosphoprotein 32 family, member B
ARNT aryl hydrocarbon receptor nuclear translocator
ARNTL aryl hydrocarbon receptor nuclear translocator-like
ATAD3B ATPase family, AAA domain containing 3B
ATG10 autophagy related 10
ATG14 autophagy related 14
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
ATG3 autophagy related 3
ATG4B autophagy related 4B, cysteine peptidase
ATG4C autophagy related 4C, cysteine peptidase
ATG5 autophagy related 5
ATG7 autophagy related 7
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide
BCLAF1 BCL2-associated transcription factor 1
BECN1 beclin 1, autophagy related
BMI1 BMI1 proto-oncogene, polycomb ring finger
BRCA2 breast cancer 2, early onset
BUB3 BUB3 mitotic checkpoint protein
BYSL bystin-like
C14ORF166 chromosome 14 open reading frame 166
C1QBP complement component 1, q subcomponent binding protein
CAB39 calcium binding protein 39
CACYBP calcyclin binding protein
CAND1 cullin-associated and neddylation-dissociated 1
CAPZA1 capping protein (actin filament) muscle Z-line, alpha 1
CAPZB capping protein (actin filament) muscle Z-line, beta
CBX2 chromobox homolog 2
CBX4 chromobox homolog 4
CBX6 chromobox homolog 6
CBX7 chromobox homolog 7
CBX8 chromobox homolog 8
CCDC8 coiled-coil domain containing 8
CCNA2 cyclin A2
CCNT1 cyclin T1
CDC27 cell division cycle 27
CDC37 cell division cycle 37
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase
CDK9 cyclin-dependent kinase 9
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
CHCHD2 coiled-coil-helix-coiled-coil-helix domain containing 2
CIAO1 cytosolic iron-sulfur assembly component 1
CLK3 CDC-like kinase 3
CLPTM1L CLPTM1-like
CMAS cytidine monophosphate N-acetylneuraminic acid synthetase
CNBP CCHC-type zinc finger, nucleic acid binding protein
COPS2 COP9 signalosome subunit 2
COPS4 COP9 signalosome subunit 4
CREBBP CREB binding protein
CS citrate synthase
CSNK2A1 casein kinase 2, alpha 1 polypeptide
CSNK2A2 casein kinase 2, alpha prime polypeptide
CSNK2B casein kinase 2, beta polypeptide
CTBP2 C-terminal binding protein 2
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa
CTPS2 CTP synthase 2
CUL1 cullin 1
CUL2 cullin 2
CUL4B cullin 4B
DAP3 death associated protein 3
DCAF16 DDB1 and CUL4 associated factor 16
DCAF7 DDB1 and CUL4 associated factor 7
DDA1 DET1 and DDB1 associated 1
DDB1 damage-specific DNA binding protein 1, 127kDa
DDX1 DEAD (Asp-Glu-Ala-Asp) box helicase 1
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DHX57 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57
DYNLL1 dynein, light chain, LC8-type 1
DYRK1B dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
DYRK4 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4
ECT2 epithelial cell transforming 2
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
EEF2 eukaryotic translation elongation factor 2
EIF3A eukaryotic translation initiation factor 3, subunit A
EIF3CL eukaryotic translation initiation factor 3, subunit C-like
EIF3E eukaryotic translation initiation factor 3, subunit E
EIF3F eukaryotic translation initiation factor 3, subunit F
EIF3H eukaryotic translation initiation factor 3, subunit H
EIF3I eukaryotic translation initiation factor 3, subunit I
EIF3M eukaryotic translation initiation factor 3, subunit M
EIF4B eukaryotic translation initiation factor 4B
EIF4EBP3 eukaryotic translation initiation factor 4E binding protein 3
ENAH enabled homolog (Drosophila)
EP300 E1A binding protein p300
EP400 E1A binding protein p400
ERH enhancer of rudimentary homolog (Drosophila)
EWSR1 EWS RNA-binding protein 1
FAF1 Fas (TNFRSF6) associated factor 1
FAM117A family with sequence similarity 117, member A
FAM117B family with sequence similarity 117, member B
FAM151B family with sequence similarity 151, member B
FAM53C family with sequence similarity 53, member C
FAM98A family with sequence similarity 98, member A
FARSA phenylalanyl-tRNA synthetase, alpha subunit
FBN2 fibrillin 2
FBXO3 F-box protein 3
FBXO45 F-box protein 45
FEM1A fem-1 homolog a (C. elegans)
FEM1C fem-1 homolog c (C. elegans)
FKBP5 FK506 binding protein 5
FLNA filamin A, alpha
FNTA farnesyltransferase, CAAX box, alpha
FOXK1 forkhead box K1
GABARAP GABA(A) receptor-associated protein
GABARAPL2 GABA(A) receptor-associated protein-like 2
GARS glycyl-tRNA synthetase
GIGYF2 GRB10 interacting GYF protein 2
GLCCI1 glucocorticoid induced 1
GMPS guanine monphosphate synthase
GNB2L1 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
GPC4 glypican 4
GPX4 glutathione peroxidase 4
GRB2 growth factor receptor-bound protein 2
GTF2I general transcription factor IIi
GTF3C3 general transcription factor IIIC, polypeptide 3, 102kDa
GTSE1 G-2 and S-phase expressed 1
GYS1 glycogen synthase 1 (muscle)
H2AFJ H2A histone family, member J
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit
HADHB hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit
HAT1 histone acetyltransferase 1
HBA2 hemoglobin, alpha 2
HECTD1 HECT domain containing E3 ubiquitin protein ligase 1
HIST1H1C histone cluster 1, H1c
HIST1H1D histone cluster 1, H1d
HIST1H2BN histone cluster 1, H2bn
HIST1H4F histone cluster 1, H4f
HIST2H2BE histone cluster 2, H2be
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1
HNRNPAB heterogeneous nuclear ribonucleoprotein A/B
HNRNPH3 heterogeneous nuclear ribonucleoprotein H3 (2H9)
HNRNPM heterogeneous nuclear ribonucleoprotein M
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSPA1B heat shock 70kDa protein 1B
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPA8 heat shock 70kDa protein 8
HSPH1 heat shock 105kDa/110kDa protein 1
IQGAP1 IQ motif containing GTPase activating protein 1
ITCH itchy E3 ubiquitin protein ligase
IVNS1ABP influenza virus NS1A binding protein
KAT8 K(lysine) acetyltransferase 8
KCTD6 potassium channel tetramerization domain containing 6
KDM1A lysine (K)-specific demethylase 1A
KDM3A lysine (K)-specific demethylase 3A
KEAP1 kelch-like ECH-associated protein 1
KIAA0226 KIAA0226
KIAA0232 KIAA0232
KIAA0930 KIAA0930
KIF23 kinesin family member 23
KLHL13 kelch-like family member 13
KLHL22 kelch-like family member 22
KLHL9 kelch-like family member 9
LANCL2 LanC lantibiotic synthetase component C-like 2 (bacterial)
LIMS1 LIM and senescent cell antigen-like domains 1
LONRF2 LON peptidase N-terminal domain and ring finger 2
LZTS2 leucine zipper, putative tumor suppressor 2
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast)
MAMDC2 MAM domain containing 2
MAP1B microtubule-associated protein 1B
MAP1LC3B2 microtubule-associated protein 1 light chain 3 beta 2
MAP1LC3C microtubule-associated protein 1 light chain 3 gamma
MAP2K3 mitogen-activated protein kinase kinase 3
MAPK14 mitogen-activated protein kinase 14
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MAPKAPK3 mitogen-activated protein kinase-activated protein kinase 3
MARCKSL1 MARCKS-like 1
MAX MYC associated factor X
MAZ MYC-associated zinc finger protein (purine-binding transcription factor)
MKNK1 MAP kinase interacting serine/threonine kinase 1
MKNK2 MAP kinase interacting serine/threonine kinase 2
MLLT1 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1
MPHOSPH9 M-phase phosphoprotein 9
MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
MRPL12 mitochondrial ribosomal protein L12
MRPL17 mitochondrial ribosomal protein L17
MRPS22 mitochondrial ribosomal protein S22
MRPS23 mitochondrial ribosomal protein S23
MRPS28 mitochondrial ribosomal protein S28
MRPS35 mitochondrial ribosomal protein S35
MSL3 male-specific lethal 3 homolog (Drosophila)
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYCBP2 MYC binding protein 2, E3 ubiquitin protein ligase
MYH10 myosin, heavy chain 10, non-muscle
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric
MYO6 myosin VI
NAP1L1 nucleosome assembly protein 1-like 1
NASP nuclear autoantigenic sperm protein (histone-binding)
NEB nebulin
NEDD8 neural precursor cell expressed, developmentally down-regulated 8
NET1 neuroepithelial cell transforming 1
NOTCH1 notch 1
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NQO2 NAD(P)H dehydrogenase, quinone 2
NRBF2 nuclear receptor binding factor 2
NRF1 nuclear respiratory factor 1
NUDCD3 NudC domain containing 3
NUP153 nucleoporin 153kDa
OBSL1 obscurin-like 1
OSBP oxysterol binding protein
OSBPL10 oxysterol binding protein-like 10
OSBPL9 oxysterol binding protein-like 9
OTUD1 OTU deubiquitinase 1
OTUD5 OTU deubiquitinase 5
PABPC1 poly(A) binding protein, cytoplasmic 1
PCGF2 polycomb group ring finger 2
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PDCD5 programmed cell death 5
PGAM5 phosphoglycerate mutase family member 5
PGGT1B protein geranylgeranyltransferase type I, beta subunit
PHC1 polyhomeotic homolog 1 (Drosophila)
PHC2 polyhomeotic homolog 2 (Drosophila)
PHC3 polyhomeotic homolog 3 (Drosophila)
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3
PIK3R4 phosphoinositide-3-kinase, regulatory subunit 4
PKLR pyruvate kinase, liver and RBC
PKN2 protein kinase N2
POLDIP2 polymerase (DNA-directed), delta interacting protein 2
POLR1A polymerase (RNA) I polypeptide A, 194kDa
POLR1B polymerase (RNA) I polypeptide B, 128kDa
POLR1C polymerase (RNA) I polypeptide C, 30kDa
POLR2C polymerase (RNA) II (DNA directed) polypeptide C, 33kDa
POLR2E polymerase (RNA) II (DNA directed) polypeptide E, 25kDa
POLR2H polymerase (RNA) II (DNA directed) polypeptide H
PPARG peroxisome proliferator-activated receptor gamma
PPM1G protein phosphatase, Mg2+/Mn2+ dependent, 1G
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme
PPP1CB protein phosphatase 1, catalytic subunit, beta isozyme
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme
PPP1R3F protein phosphatase 1, regulatory subunit 3F
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PRMT3 protein arginine methyltransferase 3
PRPF19 pre-mRNA processing factor 19
PRPF8 pre-mRNA processing factor 8
PRRC2B proline-rich coiled-coil 2B
PSMC1 proteasome (prosome, macropain) 26S subunit, ATPase, 1
PSMC2 proteasome (prosome, macropain) 26S subunit, ATPase, 2
PSMC4 proteasome (prosome, macropain) 26S subunit, ATPase, 4
PSMC5 proteasome (prosome, macropain) 26S subunit, ATPase, 5
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
PTGES3 prostaglandin E synthase 3 (cytosolic)
RAD50 RAD50 homolog (S. cerevisiae)
RAE1 ribonucleic acid export 1
RANBP9 RAN binding protein 9
RB1 retinoblastoma 1
RB1CC1 RB1-inducible coiled-coil 1
RBBP7 retinoblastoma binding protein 7
RBL1 retinoblastoma-like 1
RBL2 retinoblastoma-like 2
RBM15B RNA binding motif protein 15B
RCN1 reticulocalbin 1, EF-hand calcium binding domain
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RING1 ring finger protein 1
RNF169 ring finger protein 169
RNF2 ring finger protein 2
RPAP3 RNA polymerase II associated protein 3
RPL10 ribosomal protein L10
RPL10A ribosomal protein L10a
RPL11 ribosomal protein L11
RPL14 ribosomal protein L14
RPL18 ribosomal protein L18
RPL18A ribosomal protein L18a
RPL22 ribosomal protein L22
RPL23 ribosomal protein L23
RPL23A ribosomal protein L23a
RPL24 ribosomal protein L24
RPL27 ribosomal protein L27
RPL27A ribosomal protein L27a
RPL28 ribosomal protein L28
RPL29 ribosomal protein L29
RPL30 ribosomal protein L30
RPL31 ribosomal protein L31
RPL32 ribosomal protein L32
RPL36 ribosomal protein L36
RPL4 ribosomal protein L4
RPL6 ribosomal protein L6
RPL7 ribosomal protein L7
RPL8 ribosomal protein L8
RPLP0 ribosomal protein, large, P0
RPLP2 ribosomal protein, large, P2
RPS11 ribosomal protein S11
RPS12 ribosomal protein S12
RPS13 ribosomal protein S13
RPS14 ribosomal protein S14
RPS15A ribosomal protein S15a
RPS16 ribosomal protein S16
RPS19 ribosomal protein S19
RPS2 ribosomal protein S2
RPS20 ribosomal protein S20
RPS23 ribosomal protein S23
RPS25 ribosomal protein S25
RPS27L ribosomal protein S27-like
RPS3 ribosomal protein S3
RPS4X ribosomal protein S4, X-linked
RPS5 ribosomal protein S5
RPS6 ribosomal protein S6
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
RPS8 ribosomal protein S8
RPS9 ribosomal protein S9
RPSA ribosomal protein SA
RRP1B ribosomal RNA processing 1B
RTCB RNA 2',3'-cyclic phosphate and 5'-OH ligase
RYBP RING1 and YY1 binding protein
S100A8 S100 calcium binding protein A8
SART3 squamous cell carcinoma antigen recognized by T cells 3
SCHIP1 schwannomin interacting protein 1
SEC23A Sec23 homolog A (S. cerevisiae)
SEC61A1 Sec61 alpha 1 subunit (S. cerevisiae)
SERBP1 SERPINE1 mRNA binding protein 1
SET SET nuclear proto-oncogene
SETDB1 SET domain, bifurcated 1
SF3A1 splicing factor 3a, subunit 1, 120kDa
SIPA1L1 signal-induced proliferation-associated 1 like 1
SIPA1L2 signal-induced proliferation-associated 1 like 2
SIPA1L3 signal-induced proliferation-associated 1 like 3
SIRT1 sirtuin 1
SIRT7 sirtuin 7
SKI SKI proto-oncogene
SLC25A4 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4
SMAD6 SMAD family member 6
SMAD7 SMAD family member 7
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
SMC1A structural maintenance of chromosomes 1A
SMURF2 SMAD specific E3 ubiquitin protein ligase 2
SNRNP200 small nuclear ribonucleoprotein 200kDa (U5)
SNRNP70 small nuclear ribonucleoprotein 70kDa (U1)
SNRPD1 small nuclear ribonucleoprotein D1 polypeptide 16kDa
SPRYD3 SPRY domain containing 3
SPTLC1 serine palmitoyltransferase, long chain base subunit 1
SRRM2 serine/arginine repetitive matrix 2
SSX2IP synovial sarcoma, X breakpoint 2 interacting protein
STK11 serine/threonine kinase 11
STRADA STE20-related kinase adaptor alpha
STRADB STE20-related kinase adaptor beta
SUMO1 small ubiquitin-like modifier 1
SUMO2 small ubiquitin-like modifier 2
SUPT4H1 suppressor of Ty 4 homolog 1 (S. cerevisiae)
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
TBL3 transducin (beta)-like 3
TBP TATA box binding protein
TCEAL1 transcription elongation factor A (SII)-like 1
TCEAL2 transcription elongation factor A (SII)-like 2
TCEAL4 transcription elongation factor A (SII)-like 4
TCEB1 transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)
TECR trans-2,3-enoyl-CoA reductase
TFCP2 transcription factor CP2
TGFBR1 transforming growth factor, beta receptor 1
THRAP3 thyroid hormone receptor associated protein 3
TICAM2 toll-like receptor adaptor molecule 2
TIPIN TIMELESS interacting protein
TMED1 transmembrane emp24 protein transport domain containing 1
TMED10 transmembrane emp24-like trafficking protein 10 (yeast)
TMED2 transmembrane emp24 domain trafficking protein 2
TMED7 transmembrane emp24 protein transport domain containing 7
TMED9 transmembrane emp24 protein transport domain containing 9
TNRC6B trinucleotide repeat containing 6B
TP53 tumor protein p53
TRIM11 tripartite motif containing 11
TRIP12 thyroid hormone receptor interactor 12
TROAP trophinin associated protein
TSR1 TSR1, 20S rRNA accumulation, homolog (S. cerevisiae)
TTC37 tetratricopeptide repeat domain 37
TUBA1A tubulin, alpha 1a
TUBB tubulin, beta class I
TUBB4B tubulin, beta 4B class IVb
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1
UBB ubiquitin B
UBC ubiquitin C
UBD ubiquitin D
UBE2O ubiquitin-conjugating enzyme E2O
UBR4 ubiquitin protein ligase E3 component n-recognin 4
UBR5 ubiquitin protein ligase E3 component n-recognin 5
UHRF1 ubiquitin-like with PHD and ring finger domains 1
USP15 ubiquitin specific peptidase 15
USP34 ubiquitin specific peptidase 34
USP4 ubiquitin specific peptidase 4 (proto-oncogene)
USP7 ubiquitin specific peptidase 7 (herpes virus-associated)
USP9X ubiquitin specific peptidase 9, X-linked
UVRAG UV radiation resistance associated
VARS valyl-tRNA synthetase
VPRBP Vpr (HIV-1) binding protein
WBP5 WW domain binding protein 5
WDR33 WD repeat domain 33
WDR5 WD repeat domain 5
WDR6 WD repeat domain 6
WDR61 WD repeat domain 61
WRAP53 WD repeat containing, antisense to TP53
WRNIP1 Werner helicase interacting protein 1
WWP1 WW domain containing E3 ubiquitin protein ligase 1
WWP2 WW domain containing E3 ubiquitin protein ligase 2
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
XPC xeroderma pigmentosum, complementation group C
XPO7 exportin 7
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6
YAF2 YY1 associated factor 2
YBEY ybeY metallopeptidase (putative)
YBX1 Y box binding protein 1
YBX3 Y box binding protein 3
YME1L1 YME1-like 1 ATPase
ZFP91 ZFP91 zinc finger protein
ZMYM4 zinc finger, MYM-type 4
ZMYM6 zinc finger, MYM-type 6
ZNF24 zinc finger protein 24
ZNF516 zinc finger protein 516
ZNF579 zinc finger protein 579
ZRANB2 zinc finger, RAN-binding domain containing 2