USP28 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description ubiquitin specific peptidase 28|The ubiquitin-dependent protein degradation pathway is essential for proteolysis of intracellular proteins and peptides. Enzymes that remove ubiquitin from ubiquitin-conjugated peptides, like USP28, affect the fate and degradation of intracellular proteins and are essential for maintenance of cell-free ubiquitin pools (Valero et al., 2001).[supplied by OMIM, Mar 2008] (NCBI Entrez Gene Database, 57646)
External Link https://ncbi.nlm.nih.gov/gene/57646
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Genes

500 genes differentially expressed following the USP28 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
APOD apolipoprotein D 0.0166252
FN1 fibronectin 1 0.014447
SRPX sushi-repeat containing protein, X-linked 0.0139944
PROM1 prominin 1 0.0132138
ZNF721 zinc finger protein 721 0.0127836
NPIPB3 nuclear pore complex interacting protein family, member B3 0.0122244
SYNM synemin, intermediate filament protein 0.0121461
NOTCH2NL notch 2 N-terminal like 0.0121169
SOBP sine oculis binding protein homolog (Drosophila) 0.0119214
DLK1 delta-like 1 homolog (Drosophila) 0.0117478
BRD2 bromodomain containing 2 0.0116898
RPS4Y1 ribosomal protein S4, Y-linked 1 0.0113523
GOLGA8H golgin A8 family, member H 0.0112447
PEG10 paternally expressed 10 0.0110526
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide 0.0110257
IFI6 interferon, alpha-inducible protein 6 0.0108591
GNAS GNAS complex locus 0.0108268
GPM6B glycoprotein M6B 0.0108193
HSPA1A heat shock 70kDa protein 1A 0.0107534
SCGB2A1 secretoglobin, family 2A, member 1 0.0107014
TATDN2 TatD DNase domain containing 2 0.0105861
MRPS16 mitochondrial ribosomal protein S16 0.0105808
ASRGL1 asparaginase like 1 0.0105057
GREB1 growth regulation by estrogen in breast cancer 1 0.0104295
GOLGA8A golgin A8 family, member A 0.010318
TIMP4 TIMP metallopeptidase inhibitor 4 0.0102402
TGFBR3 transforming growth factor, beta receptor III 0.010193
A2M alpha-2-macroglobulin 0.0101883
PRR11 proline rich 11 0.0100465
PEG3 paternally expressed 3 0.0100451
MATN2 matrilin 2 0.00993027
HAUS2 HAUS augmin-like complex, subunit 2 0.00987891
ZNF160 zinc finger protein 160 0.00978037
CASP2 caspase 2, apoptosis-related cysteine peptidase 0.00973889
TFPI2 tissue factor pathway inhibitor 2 0.00972281
PTN pleiotrophin 0.00971285
PCDH9 protocadherin 9 0.00968543
MMP7 matrix metallopeptidase 7 0.00962743
NFIB nuclear factor I/B 0.0096236
THBS4 thrombospondin 4 0.00961088
PBX1 pre-B-cell leukemia homeobox 1 0.00941112
MYBPC1 myosin binding protein C, slow type 0.0093798
ACTG2 actin, gamma 2, smooth muscle, enteric 0.009353
CSAD cysteine sulfinic acid decarboxylase 0.00932967
EDNRA endothelin receptor type A 0.00931329
MSMB microseminoprotein, beta- 0.00931104
SGCE sarcoglycan, epsilon 0.00927774
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) 0.00927767
MGP matrix Gla protein 0.00920466
COCH cochlin 0.00915459
SCUBE2 signal peptide, CUB domain, EGF-like 2 0.00912083
DLG5 discs, large homolog 5 (Drosophila) 0.00910081
PKD1P1 polycystic kidney disease 1 (autosomal dominant) pseudogene 1 0.00896767
LGALS1 lectin, galactoside-binding, soluble, 1 0.00892988
EIF5A eukaryotic translation initiation factor 5A 0.00890244
DES desmin 0.00888065
PBX3 pre-B-cell leukemia homeobox 3 0.00881351
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1 0.00879434
COL9A3 collagen, type IX, alpha 3 0.00877083
COG7 component of oligomeric golgi complex 7 0.00875855
SAMD4A sterile alpha motif domain containing 4A 0.00872332
SORBS1 sorbin and SH3 domain containing 1 0.00855677
SCRG1 stimulator of chondrogenesis 1 0.00855531
G0S2 G0/G1 switch 2 0.00854285
PIP prolactin-induced protein 0.00854104
KLHL41 kelch-like family member 41 0.00843145
BCHE butyrylcholinesterase 0.0084192
MPPED2 metallophosphoesterase domain containing 2 0.00832121
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.008258
ZIC1 Zic family member 1 0.00819189
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 0.00818757
IRS2 insulin receptor substrate 2 0.00817688
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 0.00816035
TUBA1A tubulin, alpha 1a 0.00815202
FBXW12 F-box and WD repeat domain containing 12 0.00808658
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) 0.00806898
F3 coagulation factor III (thromboplastin, tissue factor) 0.00804854
NRIP3 nuclear receptor interacting protein 3 0.00803695
MAOA monoamine oxidase A 0.00802186
SCN3A sodium channel, voltage gated, type III alpha subunit 0.00801579
NAP1L1 nucleosome assembly protein 1-like 1 0.00798766
PHLDA1 pleckstrin homology-like domain, family A, member 1 0.00797069
SLC26A2 solute carrier family 26 (anion exchanger), member 2 0.00795562
AHNAK AHNAK nucleoprotein 0.00791368
ALCAM activated leukocyte cell adhesion molecule 0.007899
TRPS1 trichorhinophalangeal syndrome I 0.0078961
TACSTD2 tumor-associated calcium signal transducer 2 0.00782462
AGR2 anterior gradient 2 0.00782274
PTP4A3 protein tyrosine phosphatase type IVA, member 3 0.00779818
EPCAM epithelial cell adhesion molecule 0.00773177
ANKRD11 ankyrin repeat domain 11 0.00771645
PDGFC platelet derived growth factor C 0.00770063
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog 0.00769766
COQ8A coenzyme Q8A 0.0076956
TCF7 transcription factor 7 (T-cell specific, HMG-box) 0.00765377
GPM6A glycoprotein M6A 0.00763303
ITPKB inositol-trisphosphate 3-kinase B 0.00759211
COL6A3 collagen, type VI, alpha 3 0.00758798
NPIPA1 nuclear pore complex interacting protein family, member A1 0.00757527
ARHGAP29 Rho GTPase activating protein 29 0.00755699
INAVA innate immunity activator 0.00755123
GAD1 glutamate decarboxylase 1 (brain, 67kDa) 0.00752535
MSLN mesothelin 0.00751887
ARHGEF40 Rho guanine nucleotide exchange factor (GEF) 40 0.00751803
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 0.00751463
SCGB2A2 secretoglobin, family 2A, member 2 0.00750263
THBS2 thrombospondin 2 0.00750129
ZW10 zw10 kinetochore protein 0.00747777
MYH11 myosin, heavy chain 11, smooth muscle 0.00746161
BBX bobby sox homolog (Drosophila) 0.0074513
HELLS helicase, lymphoid-specific 0.00744986
MUC16 mucin 16, cell surface associated 0.0074077
TNNT1 troponin T type 1 (skeletal, slow) 0.00733652
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 0.00732869
IGFBP5 insulin-like growth factor binding protein 5 0.00731252
MAGED1 melanoma antigen family D1 0.00728055
OGN osteoglycin 0.00725122
SYNGR3 synaptogyrin 3 0.0072369
PRSS21 protease, serine, 21 (testisin) 0.00722472
MFSD10 major facilitator superfamily domain containing 10 0.00719362
ACTA2 actin, alpha 2, smooth muscle, aorta 0.0071925
CDH2 cadherin 2, type 1, N-cadherin (neuronal) 0.00718749
NID2 nidogen 2 (osteonidogen) 0.00716006
FHL1 four and a half LIM domains 1 0.00714373
TMSB15A thymosin beta 15a 0.00714244
NKX2-2 NK2 homeobox 2 0.00714174
VCAN versican 0.00710306
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive 0.0070808
ACTA1 actin, alpha 1, skeletal muscle 0.007079
ECM1 extracellular matrix protein 1 0.00706464
MMP16 matrix metallopeptidase 16 (membrane-inserted) 0.0070582
MEIS1 Meis homeobox 1 0.00705151
CHRDL1 chordin-like 1 0.00705091
ABHD2 abhydrolase domain containing 2 0.00701031
DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila) 0.00699239
IL17RB interleukin 17 receptor B 0.0069902
SPAG16 sperm associated antigen 16 0.00697627
VCL vinculin 0.00696104
FABP4 fatty acid binding protein 4, adipocyte 0.00695846
NEFH neurofilament, heavy polypeptide 0.00695017
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A 0.00693455
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 0.00691361
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa 0.00690847
TSPYL5 TSPY-like 5 0.0069046
LCP1 lymphocyte cytosolic protein 1 (L-plastin) 0.00689949
ACAT2 acetyl-CoA acetyltransferase 2 0.00689075
PDLIM3 PDZ and LIM domain 3 0.00688836
WIF1 WNT inhibitory factor 1 0.00688479
SERINC5 serine incorporator 5 0.00686105
DKK1 dickkopf WNT signaling pathway inhibitor 1 0.00685835
ALDH5A1 aldehyde dehydrogenase 5 family, member A1 0.00684948
IRS1 insulin receptor substrate 1 0.0068088
ARID4A AT rich interactive domain 4A (RBP1-like) 0.00680683
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 0.00678491
CROCCP2 ciliary rootlet coiled-coil, rootletin pseudogene 2 0.00675606
BASP1 brain abundant, membrane attached signal protein 1 0.00673869
SOX10 SRY (sex determining region Y)-box 10 0.00671093
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 0.00670738
MYL2 myosin, light chain 2, regulatory, cardiac, slow 0.00668778
NBPF10 neuroblastoma breakpoint family, member 10 0.00667915
MYL1 myosin, light chain 1, alkali; skeletal, fast 0.00667561
ZNF611 zinc finger protein 611 0.00666841
ALDH1A2 aldehyde dehydrogenase 1 family, member A2 0.00665373
SCD5 stearoyl-CoA desaturase 5 0.00664533
TRIM14 tripartite motif containing 14 0.00662863
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 0.00661973
BAD BCL2-associated agonist of cell death 0.00661292
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 0.00660511
KRT23 keratin 23, type I 0.00660464
AQP1 aquaporin 1 (Colton blood group) 0.00659445
DEGS1 delta(4)-desaturase, sphingolipid 1 0.00658437
SFPQ splicing factor proline/glutamine-rich 0.0065709
DMD dystrophin 0.00656317
GPR19 G protein-coupled receptor 19 0.00655129
MLF1 myeloid leukemia factor 1 0.00654254
NRCAM neuronal cell adhesion molecule 0.00652937
KIF1A kinesin family member 1A 0.00650883
COL6A2 collagen, type VI, alpha 2 0.00649391
ADCY1 adenylate cyclase 1 (brain) 0.00648377
WFS1 Wolfram syndrome 1 (wolframin) 0.00647993
CAND2 cullin-associated and neddylation-dissociated 2 (putative) 0.00647331
ANXA6 annexin A6 0.00645504
MED13L mediator complex subunit 13-like 0.00642438
PITX3 paired-like homeodomain 3 0.0064223
SFRP1 secreted frizzled-related protein 1 0.00641166
CREBBP CREB binding protein 0.00641085
TKTL1 transketolase-like 1 0.00640901
USP32P2 ubiquitin specific peptidase 32 pseudogene 2 0.00638632
TMEM100 transmembrane protein 100 0.00636777
TPPP3 tubulin polymerization-promoting protein family member 3 0.0063604
MOK MOK protein kinase 0.00635948
NR2F2 nuclear receptor subfamily 2, group F, member 2 0.00635611
GPRC5B G protein-coupled receptor, class C, group 5, member B 0.00635388
CA10 carbonic anhydrase X 0.00635079
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1 0.00632816
NOVA1 neuro-oncological ventral antigen 1 0.00631819
ABAT 4-aminobutyrate aminotransferase 0.00631513
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit 0.00629904
ZBTB20 zinc finger and BTB domain containing 20 0.00628859
ZBTB10 zinc finger and BTB domain containing 10 0.00628292
PNMA8A PNMA family member 8A 0.00628207
LDLRAD4 low density lipoprotein receptor class A domain containing 4 0.00627694
PAMR1 peptidase domain containing associated with muscle regeneration 1 0.00627037
COL9A2 collagen, type IX, alpha 2 0.00626517
ZNF512B zinc finger protein 512B 0.00624603
SMPX small muscle protein, X-linked 0.00623452
GPR17 G protein-coupled receptor 17 0.00622558
CLEC11A C-type lectin domain family 11, member A 0.00622184
EYA2 EYA transcriptional coactivator and phosphatase 2 0.00621613
CRABP1 cellular retinoic acid binding protein 1 0.00619501
SSPN sarcospan 0.00619122
GABRP gamma-aminobutyric acid (GABA) A receptor, pi 0.00618896
ATP5F1E ATP synthase F1 subunit epsilon 0.00618329
PKNOX2 PBX/knotted 1 homeobox 2 0.00616924
MAGED2 melanoma antigen family D2 0.00616138
BMP7 bone morphogenetic protein 7 0.00615886
SLN sarcolipin 0.0061573
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 0.00615324
CXADR coxsackie virus and adenovirus receptor 0.00614537
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) 0.0061169
GUSB glucuronidase, beta 0.00611112
WWTR1 WW domain containing transcription regulator 1 0.00607892
TMEM255A transmembrane protein 255A 0.00606865
SERPINA6 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6 0.00606667
PDPK1 3-phosphoinositide dependent protein kinase 1 0.006058
TMX4 thioredoxin-related transmembrane protein 4 0.00605337
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase 0.00605229
SPON2 spondin 2, extracellular matrix protein 0.00602298
SLC6A1 solute carrier family 6 (neurotransmitter transporter), member 1 0.00602157
PCP4 Purkinje cell protein 4 0.00600272
PMP2 peripheral myelin protein 2 0.00600211
COL2A1 collagen, type II, alpha 1 0.00599828
MAOB monoamine oxidase B 0.00598519
LMCD1 LIM and cysteine-rich domains 1 0.00598201
RAMP1 receptor (G protein-coupled) activity modifying protein 1 0.00597642
ATP5G2 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9) 0.00597427
NUTF2 nuclear transport factor 2 0.00596281
MAP9 microtubule-associated protein 9 0.00596124
RUFY3 RUN and FYVE domain containing 3 0.00594945
ZFP36L1 ZFP36 ring finger protein-like 1 0.00594835
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) 0.0059046
ANP32B acidic (leucine-rich) nuclear phosphoprotein 32 family, member B 0.005904
STT3A STT3A, subunit of the oligosaccharyltransferase complex (catalytic) 0.0059027
ZMIZ1 zinc finger, MIZ-type containing 1 0.00589902
ESR1 estrogen receptor 1 0.00589213
MT1M metallothionein 1M 0.00588019
CTSD cathepsin D 0.0058758
POLR1B polymerase (RNA) I polypeptide B, 128kDa 0.00586688
LAMB1 laminin, beta 1 0.00585846
CKM creatine kinase, muscle 0.00585823

decreased expression

Symbol Name Standardized Value
CTNND1 catenin (cadherin-associated protein), delta 1 -0.018569
CXCL9 chemokine (C-X-C motif) ligand 9 -0.0175086
CXCL13 chemokine (C-X-C motif) ligand 13 -0.0156408
S100A9 S100 calcium binding protein A9 -0.0136481
CA2 carbonic anhydrase II -0.012589
CXCL11 chemokine (C-X-C motif) ligand 11 -0.0119382
ZDHHC6 zinc finger, DHHC-type containing 6 -0.0117076
CXCL10 chemokine (C-X-C motif) ligand 10 -0.0116498
RHOB ras homolog family member B -0.0115929
PI3 peptidase inhibitor 3, skin-derived -0.0114309
VCAM1 vascular cell adhesion molecule 1 -0.0113288
IL32 interleukin 32 -0.0112567
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 -0.0109698
ADAMDEC1 ADAM-like, decysin 1 -0.010916
MET MET proto-oncogene, receptor tyrosine kinase -0.0105659
TMEM176B transmembrane protein 176B -0.0105346
GBP1 guanylate binding protein 1, interferon-inducible -0.0103427
TPM4 tropomyosin 4 -0.0100852
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase) -0.0100544
LGALS2 lectin, galactoside-binding, soluble, 2 -0.00973068
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) -0.0096774
GBP2 guanylate binding protein 2, interferon-inducible -0.00940608
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 -0.00928411
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) -0.00925818
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 -0.00904368
PDZK1IP1 PDZK1 interacting protein 1 -0.0090116
FUCA1 fucosidase, alpha-L- 1, tissue -0.00900601
IDO1 indoleamine 2,3-dioxygenase 1 -0.00897089
MALL mal, T-cell differentiation protein-like -0.00892459
C1QA complement component 1, q subcomponent, A chain -0.00882388
AKR1C3 aldo-keto reductase family 1, member C3 -0.00861671
CD2 CD2 molecule -0.00852689
GZMK granzyme K (granzyme 3; tryptase II) -0.00849246
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) -0.00848607
RAB32 RAB32, member RAS oncogene family -0.0084611
S100A7 S100 calcium binding protein A7 -0.00845508
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A -0.00844487
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A -0.00840155
S100A8 S100 calcium binding protein A8 -0.00836837
CLTB clathrin, light chain B -0.00825077
H1-0 H1.0 linker histone -0.00823215
CD8A CD8a molecule -0.00812958
AOC1 amine oxidase, copper containing 1 -0.00810426
HIST1H2AC histone cluster 1, H2ac -0.00809105
PLS3 plastin 3 -0.00799352
RARRES2 retinoic acid receptor responder (tazarotene induced) 2 -0.00799196
KRT16 keratin 16, type I -0.00792195
TMEM176A transmembrane protein 176A -0.00785832
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 -0.00785003
LYZ lysozyme -0.00780367
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1 -0.00779213
PDCD10 programmed cell death 10 -0.00777598
ADSL adenylosuccinate lyase -0.00777134
PRF1 perforin 1 (pore forming protein) -0.00773932
CD40 CD40 molecule, TNF receptor superfamily member 5 -0.00772868
DHRS9 dehydrogenase/reductase (SDR family) member 9 -0.00770253
CCNB1 cyclin B1 -0.00755218
AURKB aurora kinase B -0.00754518
ANPEP alanyl (membrane) aminopeptidase -0.00754204
FZD5 frizzled class receptor 5 -0.0075416
DYNLT1 dynein, light chain, Tctex-type 1 -0.00753435
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 -0.00750836
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2 -0.00749804
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 -0.00748745
JCHAIN joining chain of multimeric IgA and IgM -0.00742605
ADI1 acireductone dioxygenase 1 -0.00742115
CD69 CD69 molecule -0.00736826
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 -0.0073382
HNMT histamine N-methyltransferase -0.00730842
CEMIP cell migration inducing protein, hyaluronan binding -0.00727909
MYCL v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog -0.00727109
CST7 cystatin F (leukocystatin) -0.00722587
CXCL12 chemokine (C-X-C motif) ligand 12 -0.00720758
RPS5 ribosomal protein S5 -0.00716644
PSMB3 proteasome (prosome, macropain) subunit, beta type, 3 -0.00711356
CCL19 chemokine (C-C motif) ligand 19 -0.0071043
COG2 component of oligomeric golgi complex 2 -0.00708466
S100A12 S100 calcium binding protein A12 -0.00708073
LGALS13 lectin, galactoside-binding, soluble, 13 -0.00706999
SEPP1 selenoprotein P, plasma, 1 -0.0070593
C1QB complement component 1, q subcomponent, B chain -0.00704055
BANK1 B-cell scaffold protein with ankyrin repeats 1 -0.00702696
SLAMF7 SLAM family member 7 -0.00702166
EZR ezrin -0.00701521
SPRR2B small proline-rich protein 2B -0.00701071
STK17A serine/threonine kinase 17a -0.00697368
LIMA1 LIM domain and actin binding 1 -0.0069556
CYTIP cytohesin 1 interacting protein -0.00690939
SPINK4 serine peptidase inhibitor, Kazal type 4 -0.00683727
LEPROTL1 leptin receptor overlapping transcript-like 1 -0.00683453
TXNDC9 thioredoxin domain containing 9 -0.0068251
DSE dermatan sulfate epimerase -0.00678964
H1-2 H1.2 linker histone, cluster member -0.00677078
MMP12 matrix metallopeptidase 12 -0.00675554
POU2AF1 POU class 2 associating factor 1 -0.00673141
DSP desmoplakin -0.0066957
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O -0.00667067
IFI30 interferon, gamma-inducible protein 30 -0.00665885
VAMP5 vesicle-associated membrane protein 5 -0.00659767
DCK deoxycytidine kinase -0.00658656
GOLM1 golgi membrane protein 1 -0.00656907
HCP5 HLA complex P5 (non-protein coding) -0.00656832
CLCA4 chloride channel accessory 4 -0.0065661
BSG basigin (Ok blood group) -0.00656582
IL15RA interleukin 15 receptor, alpha -0.00653278
SCEL sciellin -0.00650287
FSTL3 follistatin-like 3 (secreted glycoprotein) -0.00649077
CYP11A1 cytochrome P450, family 11, subfamily A, polypeptide 1 -0.00646133
GALNT1 polypeptide N-acetylgalactosaminyltransferase 1 -0.00644282
ELL2 elongation factor, RNA polymerase II, 2 -0.00643321
NEDD9 neural precursor cell expressed, developmentally down-regulated 9 -0.0064267
WBP5 WW domain binding protein 5 -0.00642495
AIM2 absent in melanoma 2 -0.00642076
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) -0.00641562
KRT20 keratin 20, type I -0.00638612
DRAM1 DNA-damage regulated autophagy modulator 1 -0.00637272
EAPP E2F-associated phosphoprotein -0.00634055
RBM3 RNA binding motif (RNP1, RRM) protein 3 -0.00632791
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2 -0.00631373
LY96 lymphocyte antigen 96 -0.0062862
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) -0.00628249
MCOLN1 mucolipin 1 -0.00628057
ANXA3 annexin A3 -0.00625947
BPGM 2,3-bisphosphoglycerate mutase -0.0062553
SPRR1A small proline-rich protein 1A -0.00624981
ZG16 zymogen granule protein 16 -0.00624328
UXT ubiquitously-expressed, prefoldin-like chaperone -0.00622622
MAL mal, T-cell differentiation protein -0.00621648
PON3 paraoxonase 3 -0.00620758
S100A2 S100 calcium binding protein A2 -0.00620109
MYO1D myosin ID -0.00620032
AMDHD2 amidohydrolase domain containing 2 -0.0061971
CDA cytidine deaminase -0.0061961
PLVAP plasmalemma vesicle associated protein -0.00618656
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain -0.00618362
GSTO1 glutathione S-transferase omega 1 -0.0061829
SMCO4 single-pass membrane protein with coiled-coil domains 4 -0.00618133
IPCEF1 interaction protein for cytohesin exchange factors 1 -0.00616936
MNDA myeloid cell nuclear differentiation antigen -0.00616724
TPST2 tyrosylprotein sulfotransferase 2 -0.00615841
ITK IL2-inducible T-cell kinase -0.00615516
TOX3 TOX high mobility group box family member 3 -0.00614863
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7 -0.0061464
TCL1A T-cell leukemia/lymphoma 1A -0.00610904
CD3D CD3d molecule, delta (CD3-TCR complex) -0.00610543
CIAO3 cytosolic iron-sulfur assembly component 3 -0.00608999
HBD hemoglobin, delta -0.00605519
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B -0.00605514
SLCO4A1 solute carrier organic anion transporter family, member 4A1 -0.0060492
TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial) -0.00603789
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 -0.00603412
EREG epiregulin -0.006018
CST6 cystatin E/M -0.00600866
FARSA phenylalanyl-tRNA synthetase, alpha subunit -0.00600082
EGLN3 egl-9 family hypoxia-inducible factor 3 -0.0059993
ATP6V1E1 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1 -0.00598362
GAA glucosidase, alpha; acid -0.00598352
JMJD6 jumonji domain containing 6 -0.00598252
FLNB filamin B, beta -0.00597913
TMEM126B transmembrane protein 126B -0.00594816
RHOA ras homolog family member A -0.00593106
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 -0.00591408
RANBP1 RAN binding protein 1 -0.00591231
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1 -0.005907
SELENBP1 selenium binding protein 1 -0.00589256
INSIG2 insulin induced gene 2 -0.00589148
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 -0.00586268
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide -0.0058381
OSBPL3 oxysterol binding protein-like 3 -0.00583268
IL18 interleukin 18 -0.0058145
ALPL alkaline phosphatase, liver/bone/kidney -0.00581243
ATG5 autophagy related 5 -0.00580046
CD48 CD48 molecule -0.00579823
CCNB1IP1 cyclin B1 interacting protein 1, E3 ubiquitin protein ligase -0.00577644
RAB38 RAB38, member RAS oncogene family -0.00577558
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) -0.00576518
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase) -0.00573298
HPRT1 hypoxanthine phosphoribosyltransferase 1 -0.00573219
STON1 stonin 1 -0.00573037
TFEC transcription factor EC -0.00571427
GLS glutaminase -0.0057101
HIST1H2BH histone cluster 1, H2bh -0.0057063
CASP5 caspase 5, apoptosis-related cysteine peptidase -0.00570574
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2 -0.00570534
IDH3A isocitrate dehydrogenase 3 (NAD+) alpha -0.00569655
MGAM maltase-glucoamylase -0.005688
PRDX2 peroxiredoxin 2 -0.0056744
GPX1 glutathione peroxidase 1 -0.00566324
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1 -0.00565238
LTF lactotransferrin -0.00565111
F2RL1 coagulation factor II (thrombin) receptor-like 1 -0.00564699
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta -0.0056446
PEX3 peroxisomal biogenesis factor 3 -0.00564133
RAB9A RAB9A, member RAS oncogene family -0.00562591
WARS1 tryptophanyl-tRNA synthetase 1 -0.00562373
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9 -0.00559593
ANO10 anoctamin 10 -0.0055837
IL1R2 interleukin 1 receptor, type II -0.00558328
YIPF5 Yip1 domain family, member 5 -0.00558319
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4 -0.005574
HSPA4 heat shock 70kDa protein 4 -0.00557037
XCL1 chemokine (C motif) ligand 1 -0.00556123
CYB5A cytochrome b5 type A (microsomal) -0.00555789
DNASE1L3 deoxyribonuclease I-like 3 -0.00555048
CASP1 caspase 1, apoptosis-related cysteine peptidase -0.00554704
SLC30A5 solute carrier family 30 (zinc transporter), member 5 -0.0055302
CHMP5 charged multivesicular body protein 5 -0.00552565
SSBP3 single stranded DNA binding protein 3 -0.00552425
IRF8 interferon regulatory factor 8 -0.00551881
MAP7 microtubule-associated protein 7 -0.00551571
MAT2B methionine adenosyltransferase II, beta -0.00551521
CAPZA2 capping protein (actin filament) muscle Z-line, alpha 2 -0.00551429
RIMS3 regulating synaptic membrane exocytosis 3 -0.00551189
ALDOA aldolase A, fructose-bisphosphate -0.00550305
LGALS4 lectin, galactoside-binding, soluble, 4 -0.00549895
STX7 syntaxin 7 -0.00549881
LCK LCK proto-oncogene, Src family tyrosine kinase -0.0054922
EGR3 early growth response 3 -0.00548658
EVI2A ecotropic viral integration site 2A -0.00548106
PERP PERP, TP53 apoptosis effector -0.00547545
CASP4 caspase 4, apoptosis-related cysteine peptidase -0.00547186
HLA-F major histocompatibility complex, class I, F -0.00546019
EPHB2 EPH receptor B2 -0.00545569
HPCAL1 hippocalcin-like 1 -0.00545131
PHACTR2 phosphatase and actin regulator 2 -0.00544876
PDGFD platelet derived growth factor D -0.00544177
ETHE1 ethylmalonic encephalopathy 1 -0.00543368
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 -0.00542984
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2 -0.00542014
RAB20 RAB20, member RAS oncogene family -0.00540572
TOR4A torsin family 4, member A -0.00539732
FGL2 fibrinogen-like 2 -0.00539576
CCL5 chemokine (C-C motif) ligand 5 -0.00539206
EGR1 early growth response 1 -0.00536891
CCR7 chemokine (C-C motif) receptor 7 -0.00536736
IGSF6 immunoglobulin superfamily, member 6 -0.0053588
MXI1 MAX interactor 1, dimerization protein -0.0053584
GZMH granzyme H (cathepsin G-like 2, protein h-CCPX) -0.00534766
YAP1 Yes-associated protein 1 -0.00533985
TSPAN6 tetraspanin 6 -0.00533982
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 -0.00533693
FGGY FGGY carbohydrate kinase domain containing -0.00532553
SPRR1B small proline-rich protein 1B -0.00531627
PSMA6 proteasome (prosome, macropain) subunit, alpha type, 6 -0.00530786
RHCG Rh family, C glycoprotein -0.00529776
CDHR5 cadherin-related family member 5 -0.00529292
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide -0.00528729
C10ORF10 chromosome 10 open reading frame 10 -0.00527803
SNAP23 synaptosomal-associated protein, 23kDa -0.00527683
HPGDS hematopoietic prostaglandin D synthase -0.00526344