USP28 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description ubiquitin specific peptidase 28|The ubiquitin-dependent protein degradation pathway is essential for proteolysis of intracellular proteins and peptides. Enzymes that remove ubiquitin from ubiquitin-conjugated peptides, like USP28, affect the fate and degradation of intracellular proteins and are essential for maintenance of cell-free ubiquitin pools (Valero et al., 2001).[supplied by OMIM, Mar 2008] (NCBI Entrez Gene Database, 57646)
External Link http://www.ncbi.nlm.nih.gov/gene/57646
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Genes

102 interacting proteins for USP28 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
ANXA1 annexin A1
AQR aquarius intron-binding spliceosomal factor
ATM ATM serine/threonine kinase
ATXN3L ataxin 3-like
BAG2 BCL2-associated athanogene 2
BAG6 BCL2-associated athanogene 6
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
BTBD9 BTB (POZ) domain containing 9
CCDC8 coiled-coil domain containing 8
CCT2 chaperonin containing TCP1, subunit 2 (beta)
CCT3 chaperonin containing TCP1, subunit 3 (gamma)
CCT4 chaperonin containing TCP1, subunit 4 (delta)
CCT5 chaperonin containing TCP1, subunit 5 (epsilon)
CCT6A chaperonin containing TCP1, subunit 6A (zeta 1)
CCT7 chaperonin containing TCP1, subunit 7 (eta)
CCT8 chaperonin containing TCP1, subunit 8 (theta)
CDKN2A cyclin-dependent kinase inhibitor 2A
CIT citron rho-interacting serine/threonine kinase
CLSPN claspin
COLGALT1 collagen beta(1-O)galactosyltransferase 1
COPS4 COP9 signalosome subunit 4
CUL7 cullin 7
CUL9 cullin 9
EEF2 eukaryotic translation elongation factor 2
ELAVL1 ELAV like RNA binding protein 1
ESPL1 extra spindle pole bodies homolog 1 (S. cerevisiae)
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FBXW8 F-box and WD repeat domain containing 8
GRB2 growth factor receptor-bound protein 2
HNRNPUL1 heterogeneous nuclear ribonucleoprotein U-like 1
JOSD1 Josephin domain containing 1
KCTD10 potassium channel tetramerization domain containing 10
KCTD13 potassium channel tetramerization domain containing 13
KLHL9 kelch-like family member 9
KRT4 keratin 4, type II
LYZ lysozyme
MDC1 mediator of DNA-damage checkpoint 1
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYO6 myosin VI
NEDD8 neural precursor cell expressed, developmentally down-regulated 8
NRF1 nuclear respiratory factor 1
NUDT16L1 nudix (nucleoside diphosphate linked moiety X)-type motif 16-like 1
OLA1 Obg-like ATPase 1
OTUB1 OTU deubiquitinase, ubiquitin aldehyde binding 1
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2
PFAS phosphoribosylformylglycinamidine synthase
PIP prolactin-induced protein
PJA1 praja ring finger 1, E3 ubiquitin protein ligase
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLOD3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
PPM1G protein phosphatase, Mg2+/Mn2+ dependent, 1G
PYCRL pyrroline-5-carboxylate reductase-like
RABGAP1 RAB GTPase activating protein 1
RBX1 ring-box 1, E3 ubiquitin protein ligase
RCHY1 ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase
RFFL ring finger and FYVE-like domain containing E3 ubiquitin protein ligase
RPL5 ribosomal protein L5
SENP8 SUMO/sentrin specific peptidase family member 8
SKP1 S-phase kinase-associated protein 1
SMG5 SMG5 nonsense mediated mRNA decay factor
SMG7 SMG7 nonsense mediated mRNA decay factor
STAM signal transducing adaptor molecule (SH3 domain and ITAM motif) 1
STAMBP STAM binding protein
SUMO2 small ubiquitin-like modifier 2
TCP1 t-complex 1
TDRD12 tudor domain containing 12
TP53 tumor protein p53
TP53BP1 tumor protein p53 binding protein 1
TRAF1 TNF receptor-associated factor 1
TRIM55 tripartite motif containing 55
TRIM63 tripartite motif containing 63, E3 ubiquitin protein ligase
TSPAN10 tetraspanin 10
TSPYL4 TSPY-like 4
TUBB tubulin, beta class I
TUBB2A tubulin, beta 2A class IIa
TUBB3 tubulin, beta 3 class III
TWF1 twinfilin actin binding protein 1
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1
UBC ubiquitin C
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
UCHL3 ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)
UCHL5 ubiquitin carboxyl-terminal hydrolase L5
USO1 USO1 vesicle transport factor
USP14 ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)
USP15 ubiquitin specific peptidase 15
USP20 ubiquitin specific peptidase 20
USP21 ubiquitin specific peptidase 21
USP25 ubiquitin specific peptidase 25
USP33 ubiquitin specific peptidase 33
USP4 ubiquitin specific peptidase 4 (proto-oncogene)
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
USP51 ubiquitin specific peptidase 51
USP7 ubiquitin specific peptidase 7 (herpes virus-associated)
USP8 ubiquitin specific peptidase 8
WRNIP1 Werner helicase interacting protein 1
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
ZC3H4 zinc finger CCCH-type containing 4
ZCCHC8 zinc finger, CCHC domain containing 8
ZG16B zymogen granule protein 16B