USP5 Gene Set

Dataset MSigDB Cancer Gene Co-expression Modules
Category transcriptomics
Type co-expressed gene
Description ubiquitin specific peptidase 5 (isopeptidase T)|Ubiquitin (see MIM 191339)-dependent proteolysis is a complex pathway of protein metabolism implicated in such diverse cellular functions as maintenance of chromatin structure, receptor function, and degradation of abnormal proteins. A late step of the process involves disassembly of the polyubiquitin chains on degraded proteins into ubiquitin monomers. USP5 disassembles branched polyubiquitin chains by a sequential exo mechanism, starting at the proximal end of the chain (Wilkinson et al., 1995 [PubMed 7578059]).[supplied by OMIM, Mar 2010] (NCBI Entrez Gene Database, 8078)
External Link http://www.broadinstitute.org/gsea/msigdb/cards/MORF_USP5
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Genes

50 co-expressed genes for USP5 from the MSigDB Cancer Gene Co-expression Modules dataset.

Symbol Name
AATF apoptosis antagonizing transcription factor
AFG3L2 AFG3-like AAA ATPase 2
AGPAT1 1-acylglycerol-3-phosphate O-acyltransferase 1
BMS1 BMS1 ribosome biogenesis factor
CALM2 calmodulin 2 (phosphorylase kinase, delta)
CNP 2',3'-cyclic nucleotide 3' phosphodiesterase
CS citrate synthase
CTDNEP1 CTD nuclear envelope phosphatase 1
DDB1 damage-specific DNA binding protein 1, 127kDa
DNAJC8 DnaJ (Hsp40) homolog, subfamily C, member 8
DRG1 developmentally regulated GTP binding protein 1
EBP emopamil binding protein (sterol isomerase)
EIF6 eukaryotic translation initiation factor 6
ELK1 ELK1, member of ETS oncogene family
ESYT1 extended synaptotagmin-like protein 1
FAM189B family with sequence similarity 189, member B
GNL2 guanine nucleotide binding protein-like 2 (nucleolar)
GPAA1 glycosylphosphatidylinositol anchor attachment 1
HTATSF1 HIV-1 Tat specific factor 1
ILF2 interleukin enhancer binding factor 2
ILVBL ilvB (bacterial acetolactate synthase)-like
MEA1 male-enhanced antigen 1
METAP1 methionyl aminopeptidase 1
MFN2 mitofusin 2
MRPL28 mitochondrial ribosomal protein L28
MTX1 metaxin 1
NAP1L4 nucleosome assembly protein 1-like 4
NELFB negative elongation factor complex member B
NHP2L1 NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae)
NUP188 nucleoporin 188kDa
OTUB1 OTU deubiquitinase, ubiquitin aldehyde binding 1
PARN poly(A)-specific ribonuclease
PHB prohibitin
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
PPP1R11 protein phosphatase 1, regulatory (inhibitor) subunit 11
PRKAG1 protein kinase, AMP-activated, gamma 1 non-catalytic subunit
PSMB6 proteasome (prosome, macropain) subunit, beta type, 6
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
PSMD3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3
PWP1 PWP1 homolog (S. cerevisiae)
RING1 ring finger protein 1
RPA2 replication protein A2, 32kDa
STARD7 StAR-related lipid transfer (START) domain containing 7
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TOMM34 translocase of outer mitochondrial membrane 34
TXLNA taxilin alpha
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
WDR18 WD repeat domain 18
XPO6 exportin 6
ZPR1 ZPR1 zinc finger