Unconsciousness Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D014474
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Genes

141 genes/proteins associated with the disease Unconsciousness from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
TRH thyrotropin-releasing hormone 2.88009
CCK cholecystokinin 2.88009
FOS FBJ murine osteosarcoma viral oncogene homolog 1.97757
JUN jun proto-oncogene 1.91217
TNF tumor necrosis factor 1.8684
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 1.8559
MAPK3 mitogen-activated protein kinase 3 1.81665
MAPK1 mitogen-activated protein kinase 1 1.80756
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1 1.76072
PRL prolactin 1.75758
CRH corticotropin releasing hormone 1.73698
BDNF brain-derived neurotrophic factor 1.7319
GABRG2 gamma-aminobutyric acid (GABA) A receptor, gamma 2 1.70471
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 1.69638
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 1.68106
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.66576
DRD2 dopamine receptor D2 1.66081
NPY neuropeptide Y 1.62335
GSK3B glycogen synthase kinase 3 beta 1.61851
SLC22A2 solute carrier family 22 (organic cation transporter), member 2 1.61851
ICAM1 intercellular adhesion molecule 1 1.61621
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 1.60758
IL1B interleukin 1, beta 1.55574
NOS2 nitric oxide synthase 2, inducible 1.55427
NR1I2 nuclear receptor subfamily 1, group I, member 2 1.5311
OPRM1 opioid receptor, mu 1 1.5108
CASP8 caspase 8, apoptosis-related cysteine peptidase 1.49174
TH tyrosine hydroxylase 1.48838
MAPK8 mitogen-activated protein kinase 8 1.48531
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A 1.47452
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.46701
EGR1 early growth response 1 1.44899
FAS Fas cell surface death receptor 1.44708
IL6 interleukin 6 1.43782
SOD2 superoxide dismutase 2, mitochondrial 1.43537
MPO myeloperoxidase 1.42831
PENK proenkephalin 1.42642
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2 1.42047
JUNB jun B proto-oncogene 1.41694
BCL2 B-cell CLL/lymphoma 2 1.41613
CAT catalase 1.39507
DRD1 dopamine receptor D1 1.38974
PDYN prodynorphin 1.38807
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 1.38469
LHB luteinizing hormone beta polypeptide 1.36961
CXCL8 chemokine (C-X-C motif) ligand 8 1.36619
GAD1 glutamate decarboxylase 1 (brain, 67kDa) 1.36104
BCL2L1 BCL2-like 1 1.35213
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6 1.34606
GABRB1 gamma-aminobutyric acid (GABA) A receptor, beta 1 1.34547
GABRA6 gamma-aminobutyric acid (GABA) A receptor, alpha 6 1.34024
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B 1.3385
OXT oxytocin/neurophysin I prepropeptide 1.33642
REN renin 1.33316
GRIA3 glutamate receptor, ionotropic, AMPA 3 1.32846
GABRB3 gamma-aminobutyric acid (GABA) A receptor, beta 3 1.32518
GRIK2 glutamate receptor, ionotropic, kainate 2 1.32221
POMC proopiomelanocortin 1.31626
IFNG interferon, gamma 1.30881
CALR calreticulin 1.30512
PER1 period circadian clock 1 1.29657
BAX BCL2-associated X protein 1.29287
GABRD gamma-aminobutyric acid (GABA) A receptor, delta 1.2895
NPPA natriuretic peptide A 1.28364
GRIA1 glutamate receptor, ionotropic, AMPA 1 1.27626
CNR1 cannabinoid receptor 1 (brain) 1.25369
SLC22A3 solute carrier family 22 (organic cation transporter), member 3 1.24718
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.23074
OPRK1 opioid receptor, kappa 1 1.2279
IL1A interleukin 1, alpha 1.22664
IL2 interleukin 2 1.22306
ADORA2A adenosine A2a receptor 1.22048
FOXO1 forkhead box O1 1.21823
NFE2L2 nuclear factor, erythroid 2-like 2 1.21402
TP53 tumor protein p53 1.2137
HMOX1 heme oxygenase 1 1.21271
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.20295
ADCY8 adenylate cyclase 8 (brain) 1.19639
POLR2F polymerase (RNA) II (DNA directed) polypeptide F 1.19639
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 1.19607
GRIA2 glutamate receptor, ionotropic, AMPA 2 1.19379
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic 1.19014
IL4 interleukin 4 1.18521
AVP arginine vasopressin 1.18359
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 1.17629
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 1.165
GRIK5 glutamate receptor, ionotropic, kainate 5 1.15865
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7 1.15865
SLC17A6 solute carrier family 17 (vesicular glutamate transporter), member 6 1.14747
VEGFA vascular endothelial growth factor A 1.1461
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme 1.14541
DUSP1 dual specificity phosphatase 1 1.13827
RB1 retinoblastoma 1 1.13621
TAC1 tachykinin, precursor 1 1.12838
HSPA1A heat shock 70kDa protein 1A 1.12838
IL10 interleukin 10 1.12634
GAL galanin/GMAP prepropeptide 1.12599
POR P450 (cytochrome) oxidoreductase 1.12391
RXRG retinoid X receptor, gamma 1.11775
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) 1.11186
PPP1R1B protein phosphatase 1, regulatory (inhibitor) subunit 1B 1.10734
NR1I3 nuclear receptor subfamily 1, group I, member 3 1.10424
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 1.10211
GABRA4 gamma-aminobutyric acid (GABA) A receptor, alpha 4 1.09857
GPT glutamic-pyruvate transaminase (alanine aminotransferase) 1.09716
IGF1 insulin-like growth factor 1 (somatomedin C) 1.09154
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 1.08196
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 1.08126
PRKCG protein kinase C, gamma 1.0766
INS insulin 1.07589
CREB1 cAMP responsive element binding protein 1 1.07589
GFAP glial fibrillary acidic protein 1.07269
CCL2 chemokine (C-C motif) ligand 2 1.07234
NEFH neurofilament, heavy polypeptide 1.07128
NOS1 nitric oxide synthase 1 (neuronal) 1.06552
CDK5 cyclin-dependent kinase 5 1.06406
HIGD1A HIG1 hypoxia inducible domain family, member 1A 1.06406
GLDC glycine dehydrogenase (decarboxylating) 1.06008
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 1.05648
SLC22A1 solute carrier family 22 (organic cation transporter), member 1 1.05386
PRKACB protein kinase, cAMP-dependent, catalytic, beta 1.05274
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2 1.04904
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 1.04868
PRKCA protein kinase C, alpha 1.04831
MBP myelin basic protein 1.04684
FSHB follicle stimulating hormone, beta polypeptide 1.04163
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) 1.04051
MAP2K1 mitogen-activated protein kinase kinase 1 1.04014
PLAT plasminogen activator, tissue 1.02821
REM2 RAS (RAD and GEM)-like GTP binding 2 1.02708
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19 1.02559
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 1.02559
TLR4 toll-like receptor 4 1.02447
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 1.02077
CLU clusterin 1.01928
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.0189
GRIN2C glutamate receptor, ionotropic, N-methyl D-aspartate 2C 1.01437
CSNK2A1 casein kinase 2, alpha 1 polypeptide 1.01399
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 1.01399
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1 1.01099
RGS2 regulator of G-protein signaling 2 1.01099