| Dataset | DeepCoverMOA Drug Mechanisms of Action |
| Category | proteomics |
| Type | drug perturbation |
| Description | A straight-chain, eleven-carbon saturated medium-chain fatty acid found in body fluids; the most fungitoxic of the C7:0 - C18:0 fatty acid series. (Chemical Entities of Biological Interest Ontology, CHEBI_32368) |
| External Link | https://pubchem.ncbi.nlm.nih.gov/compound/8180 |
| Similar Terms | |
| Downloads & Tools |
200 proteins with high or low expression in Undecanoic acid relative to other proteins from the DeepCoverMOA Drug Mechanisms of Action dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PMS2 | PMS2 postmeiotic segregation increased 2 (S. cerevisiae) | 3.03 |
| GPANK1 | G patch domain and ankyrin repeats 1 | 2.78 |
| PLEKHH2 | pleckstrin homology domain containing, family H (with MyTH4 domain) member 2 | 1.02 |
| KMT2B | lysine (K)-specific methyltransferase 2B | 0.82 |
| COL17A1 | collagen, type XVII, alpha 1 | 0.76 |
| UHMK1 | U2AF homology motif (UHM) kinase 1 | 0.7 |
| PKHD1 | polycystic kidney and hepatic disease 1 (autosomal recessive) | 0.65 |
| DIPK1B | divergent protein kinase domain 1B | 0.63 |
| KIF26A | kinesin family member 26A | 0.59 |
| CEP57 | centrosomal protein 57kDa | 0.54 |
| MBP | myelin basic protein | 0.5 |
| ICA1L | islet cell autoantigen 1,69kDa-like | 0.48 |
| VWA5A | von Willebrand factor A domain containing 5A | 0.46 |
| MLX | MLX, MAX dimerization protein | 0.43 |
| ZNF236 | zinc finger protein 236 | 0.42 |
| DEPDC1 | DEP domain containing 1 | 0.4 |
| JMJD8 | jumonji domain containing 8 | 0.39 |
| STK17B | serine/threonine kinase 17b | 0.39 |
| ROS1 | ROS proto-oncogene 1 , receptor tyrosine kinase | 0.38 |
| REX1BD | required for excision 1-B domain containing | 0.37 |
| ADCY10 | adenylate cyclase 10 (soluble) | 0.37 |
| ZNF227 | zinc finger protein 227 | 0.37 |
| NGLY1 | N-glycanase 1 | 0.36 |
| MKS1 | Meckel syndrome, type 1 | 0.35 |
| NPHP4 | nephronophthisis 4 | 0.34 |
| BCL2L12 | BCL2-like 12 (proline rich) | 0.34 |
| NCOR1 | nuclear receptor corepressor 1 | 0.34 |
| C15ORF41 | chromosome 15 open reading frame 41 | 0.33 |
| ATG4D | autophagy related 4D, cysteine peptidase | 0.33 |
| LMTK2 | lemur tyrosine kinase 2 | 0.33 |
| USP19 | ubiquitin specific peptidase 19 | 0.33 |
| HHEX | hematopoietically expressed homeobox | 0.32 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.31 |
| TCTN2 | tectonic family member 2 | 0.31 |
| HSP90AA4P | heat shock protein 90kDa alpha (cytosolic), class A member 4, pseudogene | 0.31 |
| NOL3 | nucleolar protein 3 (apoptosis repressor with CARD domain) | 0.31 |
| RAD52 | RAD52 homolog (S. cerevisiae) | 0.31 |
| ZNF324 | zinc finger protein 324 | 0.31 |
| PLAAT3 | phospholipase A and acyltransferase 3 | 0.31 |
| ARL14EPL | ADP-ribosylation factor-like 14 effector protein-like | 0.31 |
| HIST2H2AA3 | histone cluster 2, H2aa3 | 0.3 |
| TMEM131L | transmembrane 131 like | 0.3 |
| LYSMD2 | LysM, putative peptidoglycan-binding, domain containing 2 | 0.3 |
| ZMYND19 | zinc finger, MYND-type containing 19 | 0.3 |
| TSPAN9 | tetraspanin 9 | 0.29 |
| ALKBH7 | alkB, alkylation repair homolog 7 (E. coli) | 0.29 |
| KLHDC3 | kelch domain containing 3 | 0.29 |
| MGA | MGA, MAX dimerization protein | 0.28 |
| DNMT3B | DNA (cytosine-5-)-methyltransferase 3 beta | 0.28 |
| R3HCC1L | R3H domain and coiled-coil containing 1-like | 0.28 |
| ATM | ATM serine/threonine kinase | 0.28 |
| SNAPC2 | small nuclear RNA activating complex, polypeptide 2, 45kDa | 0.27 |
| ZNF780A | zinc finger protein 780A | 0.27 |
| TMEM160 | transmembrane protein 160 | 0.27 |
| KCNAB2 | potassium channel, voltage gated subfamily A regulatory beta subunit 2 | 0.27 |
| TOB2 | transducer of ERBB2, 2 | 0.27 |
| ZNF691 | zinc finger protein 691 | 0.26 |
| DYRK2 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 | 0.26 |
| RXRG | retinoid X receptor, gamma | 0.26 |
| TRMO | tRNA methyltransferase O | 0.26 |
| C2CD3 | C2 calcium-dependent domain containing 3 | 0.26 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | 0.25 |
| ATL1 | atlastin GTPase 1 | 0.25 |
| ERICH1 | glutamate-rich 1 | 0.25 |
| NABP1 | nucleic acid binding protein 1 | 0.25 |
| ELFN1 | extracellular leucine-rich repeat and fibronectin type III domain containing 1 | 0.25 |
| TOX2 | TOX high mobility group box family member 2 | 0.25 |
| SLC10A4 | solute carrier family 10, member 4 | 0.25 |
| RBPJL | recombination signal binding protein for immunoglobulin kappa J region-like | 0.25 |
| CRADD | CASP2 and RIPK1 domain containing adaptor with death domain | 0.25 |
| CNTLN | centlein, centrosomal protein | 0.25 |
| SEPSECS | Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase | 0.25 |
| RPGR | retinitis pigmentosa GTPase regulator | 0.24 |
| FSD1L | fibronectin type III and SPRY domain containing 1-like | 0.24 |
| ATXN3 | ataxin 3 | 0.24 |
| C17ORF53 | chromosome 17 open reading frame 53 | 0.24 |
| TMEM199 | transmembrane protein 199 | 0.24 |
| RAB40C | RAB40C, member RAS oncogene family | 0.24 |
| NADK | NAD kinase | 0.23 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.23 |
| ZNF460 | zinc finger protein 460 | 0.23 |
| RBM41 | RNA binding motif protein 41 | 0.23 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.23 |
| TRIML2 | tripartite motif family-like 2 | 0.23 |
| SOS2 | son of sevenless homolog 2 (Drosophila) | 0.23 |
| HSP90AB4P | heat shock protein 90kDa alpha (cytosolic), class B member 4, pseudogene | 0.23 |
| ZNF414 | zinc finger protein 414 | 0.23 |
| CETN3 | centrin, EF-hand protein, 3 | 0.23 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | 0.22 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.22 |
| HDAC8 | histone deacetylase 8 | 0.22 |
| JADE1 | jade family PHD finger 1 | 0.22 |
| RSAD1 | radical S-adenosyl methionine domain containing 1 | 0.22 |
| DCLRE1A | DNA cross-link repair 1A | 0.22 |
| PMS1 | PMS1 postmeiotic segregation increased 1 (S. cerevisiae) | 0.22 |
| OGG1 | 8-oxoguanine DNA glycosylase | 0.22 |
| SPATA2L | spermatogenesis associated 2-like | 0.22 |
| FAM110C | family with sequence similarity 110, member C | 0.21 |
| BAHCC1 | BAH domain and coiled-coil containing 1 | 0.21 |
| CCDC85B | coiled-coil domain containing 85B | 0.21 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SPTBN5 | spectrin, beta, non-erythrocytic 5 | -1.01 |
| PLXNB1 | plexin B1 | -0.89 |
| ABHD4 | abhydrolase domain containing 4 | -0.8 |
| AGA | aspartylglucosaminidase | -0.73 |
| KLF4 | Kruppel-like factor 4 (gut) | -0.72 |
| SMIM26 | small integral membrane protein 26 | -0.7 |
| TRIM62 | tripartite motif containing 62 | -0.6 |
| ABHD18 | abhydrolase domain containing 18 | -0.6 |
| TSPAN33 | tetraspanin 33 | -0.56 |
| NEU3 | sialidase 3 (membrane sialidase) | -0.56 |
| WRB | tryptophan rich basic protein | -0.55 |
| ZNF431 | zinc finger protein 431 | -0.55 |
| ZBTB45 | zinc finger and BTB domain containing 45 | -0.53 |
| ULK1 | unc-51 like autophagy activating kinase 1 | -0.53 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.52 |
| PLEK | pleckstrin | -0.5 |
| TTC30B | tetratricopeptide repeat domain 30B | -0.49 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.47 |
| CCDC57 | coiled-coil domain containing 57 | -0.47 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.46 |
| GATA2 | GATA binding protein 2 | -0.46 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.45 |
| BCDIN3D | BCDIN3 domain containing | -0.44 |
| GON7 | GON7 subunit of KEOPS complex | -0.44 |
| ELOVL6 | ELOVL fatty acid elongase 6 | -0.44 |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 | -0.44 |
| HOMEZ | homeobox and leucine zipper encoding | -0.44 |
| LRFN3 | leucine rich repeat and fibronectin type III domain containing 3 | -0.43 |
| TMEM129 | transmembrane protein 129, E3 ubiquitin protein ligase | -0.43 |
| METTL4 | methyltransferase like 4 | -0.42 |
| OSBPL7 | oxysterol binding protein-like 7 | -0.42 |
| MFSD5 | major facilitator superfamily domain containing 5 | -0.4 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | -0.39 |
| HINT2 | histidine triad nucleotide binding protein 2 | -0.39 |
| PIGL | phosphatidylinositol glycan anchor biosynthesis, class L | -0.38 |
| RABEP2 | rabaptin, RAB GTPase binding effector protein 2 | -0.37 |
| APBB1 | amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) | -0.37 |
| VPS54 | vacuolar protein sorting 54 homolog (S. cerevisiae) | -0.37 |
| EVI5L | ecotropic viral integration site 5-like | -0.36 |
| DBNL | drebrin-like | -0.36 |
| TMUB1 | transmembrane and ubiquitin-like domain containing 1 | -0.36 |
| ZNF524 | zinc finger protein 524 | -0.35 |
| NRM | nurim (nuclear envelope membrane protein) | -0.35 |
| KDF1 | keratinocyte differentiation factor 1 | -0.35 |
| MID1IP1 | MID1 interacting protein 1 | -0.35 |
| DTX3L | deltex 3 like, E3 ubiquitin ligase | -0.35 |
| PPP1R16A | protein phosphatase 1, regulatory subunit 16A | -0.35 |
| PCDH1 | protocadherin 1 | -0.34 |
| PAQR4 | progestin and adipoQ receptor family member IV | -0.34 |
| RNF41 | ring finger protein 41, E3 ubiquitin protein ligase | -0.34 |
| PLPP6 | phospholipid phosphatase 6 | -0.34 |
| TMEM40 | transmembrane protein 40 | -0.34 |
| TMEM104 | transmembrane protein 104 | -0.34 |
| ADIRF | adipogenesis regulatory factor | -0.34 |
| OTX1 | orthodenticle homeobox 1 | -0.34 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.33 |
| PON3 | paraoxonase 3 | -0.33 |
| TMEM263 | transmembrane protein 263 | -0.33 |
| DXO | decapping exoribonuclease | -0.32 |
| PXMP4 | peroxisomal membrane protein 4, 24kDa | -0.32 |
| TMCO4 | transmembrane and coiled-coil domains 4 | -0.32 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.31 |
| SLC49A4 | solute carrier family 49 member 4 | -0.31 |
| CD99 | CD99 molecule | -0.31 |
| B3GNTL1 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1 | -0.31 |
| BANF1 | barrier to autointegration factor 1 | -0.31 |
| IGF1R | insulin-like growth factor 1 receptor | -0.3 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | -0.3 |
| NEIL1 | nei endonuclease VIII-like 1 (E. coli) | -0.3 |
| NFKBIE | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon | -0.3 |
| ABCC10 | ATP-binding cassette, sub-family C (CFTR/MRP), member 10 | -0.3 |
| HAL | histidine ammonia-lyase | -0.29 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.29 |
| EIF4EBP1 | eukaryotic translation initiation factor 4E binding protein 1 | -0.29 |
| GAS2L1 | growth arrest-specific 2 like 1 | -0.29 |
| ADGRG1 | adhesion G protein-coupled receptor G1 | -0.29 |
| RASAL1 | RAS protein activator like 1 (GAP1 like) | -0.29 |
| EPHX4 | epoxide hydrolase 4 | -0.29 |
| CDON | cell adhesion associated, oncogene regulated | -0.29 |
| RNF146 | ring finger protein 146 | -0.29 |
| ICK | intestinal cell (MAK-like) kinase | -0.29 |
| RPP25 | ribonuclease P/MRP 25kDa subunit | -0.29 |
| CR2 | complement component (3d/Epstein Barr virus) receptor 2 | -0.29 |
| DNM1 | dynamin 1 | -0.29 |
| FBXL8 | F-box and leucine-rich repeat protein 8 | -0.29 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.28 |
| SLC25A39 | solute carrier family 25, member 39 | -0.28 |
| LAMTOR2 | late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 | -0.28 |
| ZNF652 | zinc finger protein 652 | -0.28 |
| RAB33B | RAB33B, member RAS oncogene family | -0.28 |
| ZNF440 | zinc finger protein 440 | -0.28 |
| BORA | bora, aurora kinase A activator | -0.28 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | -0.28 |
| TP73 | tumor protein p73 | -0.28 |
| SYK | spleen tyrosine kinase | -0.28 |
| ALG3 | ALG3, alpha-1,3- mannosyltransferase | -0.27 |
| CRYBG2 | crystallin beta-gamma domain containing 2 | -0.27 |
| ASB8 | ankyrin repeat and SOCS box containing 8 | -0.27 |
| CSNK1G3 | casein kinase 1, gamma 3 | -0.27 |
| ALDH3B1 | aldehyde dehydrogenase 3 family, member B1 | -0.27 |
