| Dataset | DeepCoverMOA Drug Mechanisms of Action |
| Category | proteomics |
| Type | drug perturbation |
| External Link | https://pubchem.ncbi.nlm.nih.gov/compound/6029 |
| Similar Terms | |
| Downloads & Tools |
200 proteins with high or low expression in Uridine relative to other proteins from the DeepCoverMOA Drug Mechanisms of Action dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| KRT8 | keratin 8, type II | 0.59 |
| OSGIN1 | oxidative stress induced growth inhibitor 1 | 0.56 |
| BDNF | brain-derived neurotrophic factor | 0.49 |
| NAV2 | neuron navigator 2 | 0.47 |
| RBM48 | RNA binding motif protein 48 | 0.45 |
| GRHL1 | grainyhead-like 1 (Drosophila) | 0.44 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.43 |
| EIF5A2 | eukaryotic translation initiation factor 5A2 | 0.43 |
| MIDN | midnolin | 0.41 |
| LYST | lysosomal trafficking regulator | 0.4 |
| DAPK2 | death-associated protein kinase 2 | 0.4 |
| TTLL7 | tubulin tyrosine ligase-like family member 7 | 0.37 |
| TBC1D16 | TBC1 domain family, member 16 | 0.37 |
| TRIM9 | tripartite motif containing 9 | 0.36 |
| DOCK11 | dedicator of cytokinesis 11 | 0.36 |
| ZNF100 | zinc finger protein 100 | 0.36 |
| E2F8 | E2F transcription factor 8 | 0.35 |
| GRAMD1A | GRAM domain containing 1A | 0.35 |
| INPP5J | inositol polyphosphate-5-phosphatase J | 0.35 |
| CCN3 | cellular communication network factor 3 | 0.35 |
| PCOLCE2 | procollagen C-endopeptidase enhancer 2 | 0.35 |
| DIXDC1 | DIX domain containing 1 | 0.34 |
| DEPTOR | DEP domain containing MTOR-interacting protein | 0.34 |
| LSM11 | LSM11, U7 small nuclear RNA associated | 0.34 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.33 |
| ZNF22 | zinc finger protein 22 | 0.32 |
| SLC35F6 | solute carrier family 35, member F6 | 0.31 |
| MSX2 | msh homeobox 2 | 0.31 |
| BCLAF3 | BCLAF1 and THRAP3 family member 3 | 0.31 |
| C1ORF109 | chromosome 1 open reading frame 109 | 0.3 |
| COMMD8 | COMM domain containing 8 | 0.3 |
| ASTE1 | asteroid homolog 1 (Drosophila) | 0.3 |
| DNAH8 | dynein, axonemal, heavy chain 8 | 0.3 |
| ZSCAN29 | zinc finger and SCAN domain containing 29 | 0.29 |
| METAP2 | methionyl aminopeptidase 2 | 0.29 |
| ZNF543 | zinc finger protein 543 | 0.29 |
| POLR2H | polymerase (RNA) II (DNA directed) polypeptide H | 0.29 |
| CCDC14 | coiled-coil domain containing 14 | 0.29 |
| SH3RF2 | SH3 domain containing ring finger 2 | 0.28 |
| ZNF92 | zinc finger protein 92 | 0.28 |
| SPC24 | SPC24, NDC80 kinetochore complex component | 0.28 |
| UBE2C | ubiquitin-conjugating enzyme E2C | 0.28 |
| TMEM246 | transmembrane protein 246 | 0.28 |
| TRIAP1 | TP53 regulated inhibitor of apoptosis 1 | 0.28 |
| ARL16 | ADP-ribosylation factor-like 16 | 0.28 |
| NDUFAB1 | NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa | 0.28 |
| CEP112 | centrosomal protein 112kDa | 0.28 |
| PSMD4 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 | 0.28 |
| ZNF451 | zinc finger protein 451 | 0.27 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.27 |
| CKM | creatine kinase, muscle | 0.27 |
| NABP1 | nucleic acid binding protein 1 | 0.27 |
| SPSB3 | splA/ryanodine receptor domain and SOCS box containing 3 | 0.27 |
| C6ORF132 | chromosome 6 open reading frame 132 | 0.26 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.26 |
| CLASRP | CLK4-associating serine/arginine rich protein | 0.26 |
| EPOP | elongin BC and polycomb repressive complex 2 associated protein | 0.26 |
| EEF2KMT | eukaryotic elongation factor 2 lysine methyltransferase | 0.26 |
| TPK1 | thiamin pyrophosphokinase 1 | 0.26 |
| KIAA0825 | KIAA0825 | 0.26 |
| ZNF654 | zinc finger protein 654 | 0.26 |
| RARA | retinoic acid receptor, alpha | 0.26 |
| TSC22D2 | TSC22 domain family, member 2 | 0.26 |
| MIEF1 | mitochondrial elongation factor 1 | 0.26 |
| ACSL6 | acyl-CoA synthetase long-chain family member 6 | 0.25 |
| ZNF692 | zinc finger protein 692 | 0.25 |
| PHF1 | PHD finger protein 1 | 0.25 |
| LMF2 | lipase maturation factor 2 | 0.25 |
| TLL2 | tolloid-like 2 | 0.25 |
| MED8 | mediator complex subunit 8 | 0.25 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 0.25 |
| NFE2L3 | nuclear factor, erythroid 2-like 3 | 0.25 |
| PROS1 | protein S (alpha) | 0.25 |
| C1D | C1D nuclear receptor corepressor | 0.24 |
| GAB1 | GRB2-associated binding protein 1 | 0.24 |
| RPUSD1 | RNA pseudouridylate synthase domain containing 1 | 0.24 |
| PIGX | phosphatidylinositol glycan anchor biosynthesis, class X | 0.24 |
| DNM1 | dynamin 1 | 0.24 |
| METTL9 | methyltransferase like 9 | 0.23 |
| ZBTB44 | zinc finger and BTB domain containing 44 | 0.23 |
| NF1 | neurofibromin 1 | 0.23 |
| MTA1 | metastasis associated 1 | 0.23 |
| ATP9A | ATPase, class II, type 9A | 0.23 |
| ATP5PF | ATP synthase peripheral stalk subunit F6 | 0.23 |
| RASSF3 | Ras association (RalGDS/AF-6) domain family member 3 | 0.23 |
| CLDN3 | claudin 3 | 0.22 |
| SMIM26 | small integral membrane protein 26 | 0.22 |
| SELENOF | selenoprotein F | 0.22 |
| GVINP1 | GTPase, very large interferon inducible pseudogene 1 | 0.22 |
| SERAC1 | serine active site containing 1 | 0.22 |
| SP100 | SP100 nuclear antigen | 0.22 |
| NDUFB8 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa | 0.22 |
| ULK1 | unc-51 like autophagy activating kinase 1 | 0.22 |
| RPL36AL | ribosomal protein L36a-like | 0.22 |
| TFR2 | transferrin receptor 2 | 0.22 |
| MRPL50 | mitochondrial ribosomal protein L50 | 0.22 |
| YDJC | YdjC homolog (bacterial) | 0.22 |
| PRR36 | proline rich 36 | 0.22 |
| ANKRD36 | ankyrin repeat domain 36 | 0.22 |
| COX5A | cytochrome c oxidase subunit Va | 0.21 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA1L | heat shock 70kDa protein 1-like | -1.89 |
| KMT2B | lysine (K)-specific methyltransferase 2B | -1.64 |
| POF1B | premature ovarian failure, 1B | -1.49 |
| INO80D | INO80 complex subunit D | -1.33 |
| ADCY10 | adenylate cyclase 10 (soluble) | -1.12 |
| RUSC2 | RUN and SH3 domain containing 2 | -1.05 |
| PIP | prolactin-induced protein | -1.02 |
| PTPRB | protein tyrosine phosphatase, receptor type, B | -0.91 |
| MYH3 | myosin, heavy chain 3, skeletal muscle, embryonic | -0.86 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -0.84 |
| CRIP1 | cysteine-rich protein 1 (intestinal) | -0.8 |
| BAHCC1 | BAH domain and coiled-coil containing 1 | -0.79 |
| ZNF362 | zinc finger protein 362 | -0.76 |
| METTL26 | methyltransferase like 26 | -0.75 |
| HIST2H2AB | histone cluster 2, H2ab | -0.73 |
| RNF111 | ring finger protein 111 | -0.68 |
| TTLL4 | tubulin tyrosine ligase-like family member 4 | -0.65 |
| ZG16B | zymogen granule protein 16B | -0.63 |
| MYO7B | myosin VIIB | -0.58 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | -0.57 |
| RPL26 | ribosomal protein L26 | -0.56 |
| DOP1A | DOP1 leucine zipper like protein A | -0.55 |
| CRCP | CGRP receptor component | -0.51 |
| TET1 | tet methylcytosine dioxygenase 1 | -0.5 |
| MAP2K5 | mitogen-activated protein kinase kinase 5 | -0.49 |
| CES2 | carboxylesterase 2 | -0.48 |
| PKNOX1 | PBX/knotted 1 homeobox 1 | -0.47 |
| CDPF1 | cysteine-rich, DPF motif domain containing 1 | -0.47 |
| MYBPC1 | myosin binding protein C, slow type | -0.46 |
| NRBF2 | nuclear receptor binding factor 2 | -0.44 |
| GMCL2 | germ cell-less 2, spermatogenesis associated | -0.44 |
| BTBD3 | BTB (POZ) domain containing 3 | -0.43 |
| LAPTM4A | lysosomal protein transmembrane 4 alpha | -0.43 |
| ATXN1L | ataxin 1-like | -0.43 |
| ZNF175 | zinc finger protein 175 | -0.42 |
| VMP1 | vacuole membrane protein 1 | -0.41 |
| FAM133A | family with sequence similarity 133, member A | -0.4 |
| MYLK | myosin light chain kinase | -0.39 |
| SPPL2B | signal peptide peptidase like 2B | -0.38 |
| GATA6 | GATA binding protein 6 | -0.37 |
| NR1D2 | nuclear receptor subfamily 1, group D, member 2 | -0.37 |
| VGF | VGF nerve growth factor inducible | -0.37 |
| ICK | intestinal cell (MAK-like) kinase | -0.37 |
| PBLD | phenazine biosynthesis-like protein domain containing | -0.36 |
| LAMA2 | laminin, alpha 2 | -0.36 |
| CRELD1 | cysteine-rich with EGF-like domains 1 | -0.36 |
| FLYWCH1 | FLYWCH-type zinc finger 1 | -0.36 |
| TP73 | tumor protein p73 | -0.36 |
| SET | SET nuclear proto-oncogene | -0.35 |
| CASP9 | caspase 9, apoptosis-related cysteine peptidase | -0.35 |
| CINP | cyclin-dependent kinase 2 interacting protein | -0.35 |
| GUK1 | guanylate kinase 1 | -0.34 |
| TGFB1I1 | transforming growth factor beta 1 induced transcript 1 | -0.34 |
| ZNF839 | zinc finger protein 839 | -0.34 |
| MAPK14 | mitogen-activated protein kinase 14 | -0.34 |
| FLNB | filamin B, beta | -0.34 |
| COL14A1 | collagen, type XIV, alpha 1 | -0.34 |
| IRX4 | iroquois homeobox 4 | -0.33 |
| DDAH2 | dimethylarginine dimethylaminohydrolase 2 | -0.33 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.33 |
| TTYH3 | tweety family member 3 | -0.33 |
| SNTA1 | syntrophin, alpha 1 | -0.32 |
| ALG3 | ALG3, alpha-1,3- mannosyltransferase | -0.32 |
| HHEX | hematopoietically expressed homeobox | -0.32 |
| BDH2 | 3-hydroxybutyrate dehydrogenase, type 2 | -0.32 |
| GTF3C6 | general transcription factor IIIC, polypeptide 6, alpha 35kDa | -0.31 |
| MISP3 | MISP family member 3 | -0.31 |
| NEIL1 | nei endonuclease VIII-like 1 (E. coli) | -0.31 |
| ABHD18 | abhydrolase domain containing 18 | -0.3 |
| PGBD2 | piggyBac transposable element derived 2 | -0.3 |
| EIF4EBP2 | eukaryotic translation initiation factor 4E binding protein 2 | -0.3 |
| SPOPL | speckle-type POZ protein-like | -0.3 |
| NECTIN1 | nectin cell adhesion molecule 1 | -0.3 |
| FZD7 | frizzled class receptor 7 | -0.3 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | -0.3 |
| PDZD11 | PDZ domain containing 11 | -0.3 |
| LYRM7 | LYR motif containing 7 | -0.3 |
| HAL | histidine ammonia-lyase | -0.29 |
| SLC38A9 | solute carrier family 38, member 9 | -0.29 |
| DROSHA | drosha, ribonuclease type III | -0.29 |
| ZNF799 | zinc finger protein 799 | -0.29 |
| C1ORF226 | chromosome 1 open reading frame 226 | -0.29 |
| CAPZB | capping protein (actin filament) muscle Z-line, beta | -0.29 |
| ZFP36 | ZFP36 ring finger protein | -0.29 |
| PREX1 | phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 | -0.29 |
| RMDN2 | regulator of microtubule dynamics 2 | -0.28 |
| CCDC90B | coiled-coil domain containing 90B | -0.28 |
| AMPD1 | adenosine monophosphate deaminase 1 | -0.28 |
| SLC25A26 | solute carrier family 25 (S-adenosylmethionine carrier), member 26 | -0.28 |
| ZNF623 | zinc finger protein 623 | -0.28 |
| AMOT | angiomotin | -0.28 |
| C8ORF37 | chromosome 8 open reading frame 37 | -0.28 |
| RWDD3 | RWD domain containing 3 | -0.28 |
| CTDNEP1 | CTD nuclear envelope phosphatase 1 | -0.28 |
| ANKRD36C | ankyrin repeat domain 36C | -0.27 |
| ACVR2A | activin A receptor, type IIA | -0.27 |
| CABLES2 | Cdk5 and Abl enzyme substrate 2 | -0.27 |
| SYNE4 | spectrin repeat containing, nuclear envelope family member 4 | -0.27 |
| SNX29 | sorting nexin 29 | -0.27 |
| CASZ1 | castor zinc finger 1 | -0.27 |
