| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Uridine perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Uridine_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.290741 |
| FBN1 | fibrillin 1 | 0.139246 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.135218 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.118806 |
| COL3A1 | collagen, type III, alpha 1 | 0.111715 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.101456 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.097709 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0920388 |
| APP | amyloid beta (A4) precursor protein | 0.0902164 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0839289 |
| STC1 | stanniocalcin 1 | 0.0784183 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.075828 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0746362 |
| TMSB4X | thymosin beta 4, X-linked | 0.0742887 |
| FLNB | filamin B, beta | 0.0688685 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0649684 |
| CALR | calreticulin | 0.0637075 |
| PRSS23 | protease, serine, 23 | 0.0636647 |
| LOXL2 | lysyl oxidase-like 2 | 0.0620046 |
| SEPTIN9 | septin 9 | 0.0618519 |
| AHNAK | AHNAK nucleoprotein | 0.0616883 |
| VIM | vimentin | 0.0590104 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0586355 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0584158 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0576549 |
| DST | dystonin | 0.0536804 |
| LMNA | lamin A/C | 0.0535302 |
| MT2A | metallothionein 2A | 0.053359 |
| MSN | moesin | 0.0530196 |
| CD44 | CD44 molecule (Indian blood group) | 0.0509622 |
| COL1A2 | collagen, type I, alpha 2 | 0.0504789 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0496026 |
| PGK1 | phosphoglycerate kinase 1 | 0.0491826 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0491562 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0489978 |
| B2M | beta-2-microglobulin | 0.0489481 |
| COL5A2 | collagen, type V, alpha 2 | 0.0480466 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0462793 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0457726 |
| THBS2 | thrombospondin 2 | 0.0455401 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0445991 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0444324 |
| SFTPA2 | surfactant protein A2 | 0.0436309 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0424332 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0424231 |
| PTMA | prothymosin, alpha | 0.0419332 |
| NAV2 | neuron navigator 2 | 0.0418401 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0413995 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0408517 |
| MB21D2 | Mab-21 domain containing 2 | 0.040731 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0405596 |
| PLAT | plasminogen activator, tissue | 0.0389307 |
| CANX | calnexin | 0.0389199 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0385213 |
| TXNIP | thioredoxin interacting protein | 0.0384638 |
| IGF2R | insulin-like growth factor 2 receptor | 0.0383346 |
| CTSB | cathepsin B | 0.0378846 |
| OPTN | optineurin | 0.0375313 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0372896 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0372369 |
| CALU | calumenin | 0.0369483 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0363475 |
| UBC | ubiquitin C | 0.0363461 |
| GLG1 | golgi glycoprotein 1 | 0.0362582 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0355051 |
| SMYD3 | SET and MYND domain containing 3 | 0.0350344 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0348529 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0337693 |
| FSTL1 | follistatin-like 1 | 0.033115 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | 0.0330475 |
| DSPP | dentin sialophosphoprotein | 0.0309791 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0308322 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0304709 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 | 0.0304151 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0302912 |
| PRELID2 | PRELI domain containing 2 | 0.0299111 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0297608 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.029351 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0290781 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0288686 |
| CSTB | cystatin B (stefin B) | 0.0281565 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0281242 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0281011 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0277744 |
| PFKP | phosphofructokinase, platelet | 0.0275354 |
| OGA | O-GlcNAcase | 0.0273293 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0271555 |
| TPI1 | triosephosphate isomerase 1 | 0.0267387 |
| TPM3 | tropomyosin 3 | 0.0266408 |
| MAP4 | microtubule-associated protein 4 | 0.0264718 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0262934 |
| SBF2 | SET binding factor 2 | 0.0262511 |
| ANO6 | anoctamin 6 | 0.0261929 |
| HOOK3 | hook microtubule-tethering protein 3 | 0.0259392 |
| ZBTB41 | zinc finger and BTB domain containing 41 | 0.025707 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | 0.0256249 |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 | 0.0252784 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0250828 |
| SDC4 | syndecan 4 | 0.02503 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0248377 |
| Symbol | Name | Standardized Value |
|---|---|---|
| POTEF | POTE ankyrin domain family, member F | -0.0932697 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0579688 |
| LOX | lysyl oxidase | -0.0488938 |
| PODXL | podocalyxin-like | -0.0478216 |
| MAP1B | microtubule-associated protein 1B | -0.04409 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0412469 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0354797 |
| EGFR | epidermal growth factor receptor | -0.0324796 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.031746 |
| FN1 | fibronectin 1 | -0.0305646 |
| SUCNR1 | succinate receptor 1 | -0.0299294 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0290518 |
| CDH13 | cadherin 13 | -0.0289703 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0288844 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0285658 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0283643 |
| MEIS2 | Meis homeobox 2 | -0.0278038 |
| TAGLN2 | transgelin 2 | -0.0268375 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0251431 |
| BSG | basigin (Ok blood group) | -0.0237174 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.023607 |
| DCLK2 | doublecortin-like kinase 2 | -0.0217628 |
| LAMA5 | laminin, alpha 5 | -0.0217253 |
| TMSB10 | thymosin beta 10 | -0.0214002 |
| PRRX1 | paired related homeobox 1 | -0.0213327 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0207315 |
| FOSL1 | FOS-like antigen 1 | -0.0207227 |
| SP100 | SP100 nuclear antigen | -0.0201938 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | -0.0200509 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0197253 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0195836 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0193359 |
| L1CAM | L1 cell adhesion molecule | -0.0193174 |
| TPM4 | tropomyosin 4 | -0.0186729 |
| MNT | MAX network transcriptional repressor | -0.0181338 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0180127 |
| TCF12 | transcription factor 12 | -0.0173318 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | -0.0171817 |
| FBXO11 | F-box protein 11 | -0.017143 |
| MEF2D | myocyte enhancer factor 2D | -0.0169712 |
| PLXNA3 | plexin A3 | -0.0169485 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | -0.0169362 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | -0.0167584 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.0167019 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0166932 |
| MYADM | myeloid-associated differentiation marker | -0.0166134 |
| BCAR1 | breast cancer anti-estrogen resistance 1 | -0.0165447 |
| MTSS2 | MTSS I-BAR domain containing 2 | -0.0163417 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0163121 |
| VEGFC | vascular endothelial growth factor C | -0.0160672 |
| CCSER2 | coiled-coil serine-rich protein 2 | -0.0159972 |
| PLXNA2 | plexin A2 | -0.0159396 |
| SRPK2 | SRSF protein kinase 2 | -0.0157406 |
| CLINT1 | clathrin interactor 1 | -0.0156072 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0154826 |
| RPL28 | ribosomal protein L28 | -0.0154745 |
| TCERG1 | transcription elongation regulator 1 | -0.0153547 |
| PARD3 | par-3 family cell polarity regulator | -0.0150073 |
| IL7R | interleukin 7 receptor | -0.0150057 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.0148446 |
| RPS6 | ribosomal protein S6 | -0.0148345 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0148234 |
| MSI2 | musashi RNA-binding protein 2 | -0.0147492 |
| PER1 | period circadian clock 1 | -0.0147362 |
| SON | SON DNA binding protein | -0.0146336 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0146165 |
| STT3B | STT3B, subunit of the oligosaccharyltransferase complex (catalytic) | -0.014591 |
| TAOK1 | TAO kinase 1 | -0.0145644 |
| ZBTB43 | zinc finger and BTB domain containing 43 | -0.0145638 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0143931 |
| QKI | QKI, KH domain containing, RNA binding | -0.014351 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0143441 |
| DDR2 | discoidin domain receptor tyrosine kinase 2 | -0.0141233 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0140367 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0139283 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.013859 |
| GDF15 | growth differentiation factor 15 | -0.013734 |
| LARP1 | La ribonucleoprotein domain family, member 1 | -0.0135619 |
| SLC9A3R1 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 | -0.0134486 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | -0.013356 |
| IRF1 | interferon regulatory factor 1 | -0.0133421 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0131926 |
| PDGFB | platelet-derived growth factor beta polypeptide | -0.0131769 |
| MAML1 | mastermind-like 1 (Drosophila) | -0.013096 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0129934 |
| MEMO1 | mediator of cell motility 1 | -0.0129752 |
| PEAK1 | pseudopodium-enriched atypical kinase 1 | -0.012944 |
| RPL9 | ribosomal protein L9 | -0.0129323 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0129026 |
| HELZ | helicase with zinc finger | -0.0128479 |
| GNG12 | guanine nucleotide binding protein (G protein), gamma 12 | -0.012786 |
| TPST1 | tyrosylprotein sulfotransferase 1 | -0.012772 |
| ZMIZ2 | zinc finger, MIZ-type containing 2 | -0.0126672 |
| NEK7 | NIMA-related kinase 7 | -0.0126556 |
| NOTCH1 | notch 1 | -0.0126436 |
| UBXN4 | UBX domain protein 4 | -0.0126016 |
| JMY | junction mediating and regulatory protein, p53 cofactor | -0.0125072 |
| HLCS | holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) | -0.0124385 |
| WDR43 | WD repeat domain 43 | -0.0124033 |
| CAPNS1 | calpain, small subunit 1 | -0.0123722 |
