| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Uridine perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Uridine_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.124149 |
| ANXA1 | annexin A1 | 0.109056 |
| VIM | vimentin | 0.0710646 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0710398 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0573095 |
| RPS2 | ribosomal protein S2 | 0.0549011 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0537501 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.053102 |
| ACTG1 | actin gamma 1 | 0.05292 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0522905 |
| TPI1 | triosephosphate isomerase 1 | 0.0487482 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0470071 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.044341 |
| CALR | calreticulin | 0.0421448 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | 0.0413021 |
| RPS27A | ribosomal protein S27a | 0.0396065 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.039062 |
| PTMA | prothymosin, alpha | 0.0388162 |
| ENO1 | enolase 1, (alpha) | 0.0384168 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0383505 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0369272 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0361913 |
| RPS3 | ribosomal protein S3 | 0.0360397 |
| RPS8 | ribosomal protein S8 | 0.0353368 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0351744 |
| RPL3 | ribosomal protein L3 | 0.0347398 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0346423 |
| PGK1 | phosphoglycerate kinase 1 | 0.0339405 |
| CANX | calnexin | 0.033048 |
| MYL12B | myosin, light chain 12B, regulatory | 0.0329299 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | 0.0323944 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0321832 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.031995 |
| CPNE1 | copine I | 0.031435 |
| RPS12 | ribosomal protein S12 | 0.031139 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0307696 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0305453 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0304174 |
| SET | SET nuclear proto-oncogene | 0.0303239 |
| RACK1 | receptor for activated C kinase 1 | 0.0299192 |
| TMSB10 | thymosin beta 10 | 0.0295057 |
| DST | dystonin | 0.029325 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0293194 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.029006 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0289219 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0285771 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0282558 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0277314 |
| TPM3 | tropomyosin 3 | 0.0276212 |
| RPL37A | ribosomal protein L37a | 0.0275688 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0275147 |
| HDGF | hepatoma-derived growth factor | 0.0272166 |
| MKI67 | marker of proliferation Ki-67 | 0.026889 |
| AHNAK | AHNAK nucleoprotein | 0.0266744 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0255454 |
| KIF5B | kinesin family member 5B | 0.0253049 |
| STAG2 | stromal antigen 2 | 0.0249813 |
| DSPP | dentin sialophosphoprotein | 0.0249057 |
| NARS1 | asparaginyl-tRNA synthetase 1 | 0.0247313 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0246562 |
| XPOT | exportin, tRNA | 0.0243311 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0239364 |
| RPL4 | ribosomal protein L4 | 0.0235017 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.022934 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0227207 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0222897 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.0222745 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0221743 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0219685 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0219255 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0212195 |
| CUBN | cubilin (intrinsic factor-cobalamin receptor) | 0.0211836 |
| RPS6 | ribosomal protein S6 | 0.0211178 |
| HDLBP | high density lipoprotein binding protein | 0.0208595 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0208117 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0205923 |
| CENPF | centromere protein F, 350/400kDa | 0.0204931 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0200694 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0198813 |
| GNAS | GNAS complex locus | 0.0196617 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.019614 |
| YBX1 | Y box binding protein 1 | 0.0194537 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0193777 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0190456 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.0189587 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0189087 |
| FTL | ferritin, light polypeptide | 0.0189019 |
| LDHA | lactate dehydrogenase A | 0.0188912 |
| CAVIN1 | caveolae associated protein 1 | 0.0187348 |
| THRAP3 | thyroid hormone receptor associated protein 3 | 0.0187221 |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | 0.0186756 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | 0.0184529 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | 0.0183833 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0183247 |
| STIP1 | stress-induced phosphoprotein 1 | 0.0182754 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0182633 |
| GCG | glucagon | 0.0181742 |
| PTMS | parathymosin | 0.0180962 |
| EZR | ezrin | 0.0180895 |
| RPL37 | ribosomal protein L37 | 0.0178933 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NLGN1 | neuroligin 1 | -0.101337 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.055317 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0521176 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0434892 |
| JMJD1C | jumonji domain containing 1C | -0.0346655 |
| RTN4 | reticulon 4 | -0.0320885 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0269151 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0259681 |
| TMEM41B | transmembrane protein 41B | -0.0257769 |
| CARD16 | caspase recruitment domain family, member 16 | -0.0257442 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0251078 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0245197 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0241594 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0239728 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.0221238 |
| PFN1 | profilin 1 | -0.0220898 |
| USP34 | ubiquitin specific peptidase 34 | -0.0217032 |
| CCNL1 | cyclin L1 | -0.0207061 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0206182 |
| CELF2 | CUGBP, Elav-like family member 2 | -0.0201917 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.0199806 |
| POTEF | POTE ankyrin domain family, member F | -0.0199739 |
| TUBA1B | tubulin, alpha 1b | -0.0197504 |
| YAP1 | Yes-associated protein 1 | -0.0195969 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0193337 |
| VMP1 | vacuole membrane protein 1 | -0.0192763 |
| SMYD3 | SET and MYND domain containing 3 | -0.0191397 |
| EXOC6B | exocyst complex component 6B | -0.01913 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0187977 |
| TRA2B | transformer 2 beta homolog (Drosophila) | -0.0185993 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.018592 |
| NABP1 | nucleic acid binding protein 1 | -0.0185624 |
| NHSL1 | NHS-like 1 | -0.0182039 |
| GPHN | gephyrin | -0.0177818 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0175273 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0169634 |
| CDK17 | cyclin-dependent kinase 17 | -0.0169287 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0168722 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0167071 |
| ZNF207 | zinc finger protein 207 | -0.0163924 |
| SETD5 | SET domain containing 5 | -0.0157067 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0153264 |
| TFDP2 | transcription factor Dp-2 (E2F dimerization partner 2) | -0.0150361 |
| NEBL | nebulette | -0.014861 |
| TXNRD1 | thioredoxin reductase 1 | -0.0145304 |
| DTNA | dystrobrevin, alpha | -0.0144117 |
| NDUFV2 | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | -0.0141834 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | -0.0141321 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0137304 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.0136655 |
| NF1 | neurofibromin 1 | -0.0136494 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0136399 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0131759 |
| PIK3CA | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha | -0.0131567 |
| TENT4A | terminal nucleotidyltransferase 4A | -0.0131463 |
| WDPCP | WD repeat containing planar cell polarity effector | -0.0130546 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0129739 |
| RAD51B | RAD51 paralog B | -0.0129566 |
| NKTR | natural killer cell triggering receptor | -0.0127999 |
| VCL | vinculin | -0.0127635 |
| AHR | aryl hydrocarbon receptor | -0.0127632 |
| CSMD1 | CUB and Sushi multiple domains 1 | -0.0126444 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0125949 |
| CDC42SE2 | CDC42 small effector 2 | -0.0125916 |
| PRR16 | proline rich 16 | -0.0123947 |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit | -0.0122329 |
| ATP11B | ATPase, class VI, type 11B | -0.0121651 |
| NR5A2 | nuclear receptor subfamily 5, group A, member 2 | -0.0120692 |
| EDARADD | EDAR-associated death domain | -0.012042 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0119465 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0118921 |
| KLHL24 | kelch-like family member 24 | -0.0118501 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0118077 |
| CELF1 | CUGBP, Elav-like family member 1 | -0.0117532 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0116854 |
| COMMD10 | COMM domain containing 10 | -0.0115652 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0114571 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0114375 |
| RANBP17 | RAN binding protein 17 | -0.0113884 |
| RASAL2 | RAS protein activator like 2 | -0.0113736 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0112851 |
| TGM2 | transglutaminase 2 | -0.0111581 |
| ARL15 | ADP-ribosylation factor-like 15 | -0.0111466 |
| WWOX | WW domain containing oxidoreductase | -0.0111306 |
| ELP4 | elongator acetyltransferase complex subunit 4 | -0.0111168 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.0110892 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.011012 |
| CDK19 | cyclin-dependent kinase 19 | -0.0109955 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0109839 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0109048 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0108055 |
| TMEM167A | transmembrane protein 167A | -0.010805 |
| ZNF292 | zinc finger protein 292 | -0.0108036 |
| RBMX | RNA binding motif protein, X-linked | -0.0108017 |
| FRYL | FRY-like | -0.0107806 |
| DEK | DEK proto-oncogene | -0.0106765 |
| CXADR | coxsackie virus and adenovirus receptor | -0.0106423 |
| CAPNS1 | calpain, small subunit 1 | -0.0106051 |
| RPS24 | ribosomal protein S24 | -0.0106036 |
| EGR1 | early growth response 1 | -0.0105942 |
