| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Uridine perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Uridine_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.191668 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.156302 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.133605 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.101109 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0975701 |
| PTMA | prothymosin, alpha | 0.0764536 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.07562 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.074944 |
| VCL | vinculin | 0.0699688 |
| PRRC2C | proline-rich coiled-coil 2C | 0.068884 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0680757 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0569267 |
| DST | dystonin | 0.0568564 |
| TLE4 | transducin-like enhancer of split 4 | 0.0567471 |
| RPL3 | ribosomal protein L3 | 0.055892 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0534287 |
| MYCN | v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog | 0.0526411 |
| PLAT | plasminogen activator, tissue | 0.0513516 |
| PKM | pyruvate kinase, muscle | 0.051175 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0499916 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0481158 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0474045 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.0460345 |
| HMGB2 | high mobility group box 2 | 0.0459237 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0448235 |
| LMNA | lamin A/C | 0.044393 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0437416 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0423492 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0417114 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | 0.0400156 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.039776 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0396185 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.039415 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0393734 |
| SEPTIN9 | septin 9 | 0.0393126 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0387724 |
| RPS2 | ribosomal protein S2 | 0.0381361 |
| APP | amyloid beta (A4) precursor protein | 0.0381057 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0380366 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0379877 |
| SRSF1 | serine/arginine-rich splicing factor 1 | 0.0378665 |
| TPI1 | triosephosphate isomerase 1 | 0.0378206 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0377437 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0371064 |
| KIF5B | kinesin family member 5B | 0.0368758 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0362828 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0359779 |
| FAM13A | family with sequence similarity 13, member A | 0.0359104 |
| FUT11 | fucosyltransferase 11 (alpha (1,3) fucosyltransferase) | 0.0357683 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.035732 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0355469 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0354583 |
| AHNAK | AHNAK nucleoprotein | 0.035392 |
| PGK1 | phosphoglycerate kinase 1 | 0.0353544 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0352389 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0351911 |
| YTHDC1 | YTH domain containing 1 | 0.034294 |
| NBR1 | neighbor of BRCA1 gene 1 | 0.0339422 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0337899 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0337404 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0329048 |
| TPR | translocated promoter region, nuclear basket protein | 0.0325783 |
| TOP1 | topoisomerase (DNA) I | 0.0321376 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0320979 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0316277 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0316004 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.0315498 |
| CASC3 | cancer susceptibility candidate 3 | 0.0311201 |
| TTC17 | tetratricopeptide repeat domain 17 | 0.0310185 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0307922 |
| XRN2 | 5'-3' exoribonuclease 2 | 0.0307379 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0304675 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0303125 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0302515 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0302489 |
| B2M | beta-2-microglobulin | 0.0299538 |
| RPL19 | ribosomal protein L19 | 0.0299282 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0297205 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.029663 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0295306 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0294321 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0293948 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0289592 |
| CLTC | clathrin, heavy chain (Hc) | 0.0287624 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.0286646 |
| CALR | calreticulin | 0.0285797 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0283714 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0283083 |
| SQSTM1 | sequestosome 1 | 0.0283037 |
| RPL37A | ribosomal protein L37a | 0.02828 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0282292 |
| AMOTL1 | angiomotin like 1 | 0.0281862 |
| TBC1D15 | TBC1 domain family, member 15 | 0.0281822 |
| SLC38A2 | solute carrier family 38, member 2 | 0.028167 |
| RAB10 | RAB10, member RAS oncogene family | 0.0281107 |
| PRPF4B | pre-mRNA processing factor 4B | 0.0280964 |
| USP15 | ubiquitin specific peptidase 15 | 0.0279572 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0278543 |
| DNMBP | dynamin binding protein | 0.0277198 |
| ZNF146 | zinc finger protein 146 | 0.0275781 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | -0.354546 |
| IGF2 | insulin-like growth factor 2 | -0.159972 |
| MEIS2 | Meis homeobox 2 | -0.126119 |
| LSAMP | limbic system-associated membrane protein | -0.10681 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0832444 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.077461 |
| ZNF292 | zinc finger protein 292 | -0.0735369 |
| NRG1 | neuregulin 1 | -0.0648204 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0634492 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.062942 |
| LRFN5 | leucine rich repeat and fibronectin type III domain containing 5 | -0.0629322 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.0590143 |
| SYT1 | synaptotagmin I | -0.0541558 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0481 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | -0.0476846 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0444219 |
| TRIB2 | tribbles pseudokinase 2 | -0.0430193 |
| NDRG1 | N-myc downstream regulated 1 | -0.0429589 |
| DTNA | dystrobrevin, alpha | -0.041695 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0410039 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0400053 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0399521 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0393735 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0379062 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | -0.0373846 |
| ANGPT1 | angiopoietin 1 | -0.0367429 |
| PTEN | phosphatase and tensin homolog | -0.0362798 |
| PCDH9 | protocadherin 9 | -0.0357736 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0351169 |
| RUNX1T1 | runt-related transcription factor 1; translocated to, 1 (cyclin D-related) | -0.0343728 |
| PHIP | pleckstrin homology domain interacting protein | -0.034215 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0341931 |
| NBAS | neuroblastoma amplified sequence | -0.0341355 |
| CADM2 | cell adhesion molecule 2 | -0.0334718 |
| POTEF | POTE ankyrin domain family, member F | -0.0334349 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0322041 |
| RNF150 | ring finger protein 150 | -0.0319163 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0309771 |
| LPIN1 | lipin 1 | -0.0304276 |
| HMGA1 | high mobility group AT-hook 1 | -0.0293454 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -0.028484 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0282081 |
| DENND4C | DENN/MADD domain containing 4C | -0.0275209 |
| C1ORF21 | chromosome 1 open reading frame 21 | -0.0269051 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0267666 |
| RALYL | RALY RNA binding protein-like | -0.026631 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | -0.0265062 |
| MMP16 | matrix metallopeptidase 16 (membrane-inserted) | -0.0263382 |
| UNC5C | unc-5 homolog C (C. elegans) | -0.0257161 |
| MSI2 | musashi RNA-binding protein 2 | -0.0255091 |
| CXXC5 | CXXC finger protein 5 | -0.0254313 |
| DPH6 | diphthamine biosynthesis 6 | -0.02541 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0254061 |
| MEF2A | myocyte enhancer factor 2A | -0.0252445 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.0250601 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.0249213 |
| ADAMTS9 | ADAM metallopeptidase with thrombospondin type 1 motif, 9 | -0.02488 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0244636 |
| DIAPH2 | diaphanous-related formin 2 | -0.0243683 |
| MICU3 | mitochondrial calcium uptake family, member 3 | -0.0238425 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0236209 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0234416 |
| GNG2 | guanine nucleotide binding protein (G protein), gamma 2 | -0.0233788 |
| LARP1 | La ribonucleoprotein domain family, member 1 | -0.0230433 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0228554 |
| KCNT2 | potassium channel, sodium activated subfamily T, member 2 | -0.0226347 |
| HMGB1 | high mobility group box 1 | -0.0222597 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0222351 |
| ST6GALNAC3 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 | -0.0222129 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0219248 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0218561 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0217884 |
| NCOR2 | nuclear receptor corepressor 2 | -0.0217854 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0216875 |
| TCF12 | transcription factor 12 | -0.0216159 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0211872 |
| GPC6 | glypican 6 | -0.0210226 |
| RFX7 | regulatory factor X, 7 | -0.0210031 |
| SOX9 | SRY (sex determining region Y)-box 9 | -0.0209653 |
| CARD16 | caspase recruitment domain family, member 16 | -0.0208453 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0205463 |
| HM13 | histocompatibility (minor) 13 | -0.0205184 |
| NCAM2 | neural cell adhesion molecule 2 | -0.0204999 |
| ATXN10 | ataxin 10 | -0.0204958 |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 | -0.020197 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0201502 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.020061 |
| IREB2 | iron-responsive element binding protein 2 | -0.0200332 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | -0.0199663 |
| DCAF7 | DDB1 and CUL4 associated factor 7 | -0.0198939 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0198104 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0195513 |
| AUTS2 | autism susceptibility candidate 2 | -0.0194436 |
| SLITRK6 | SLIT and NTRK-like family, member 6 | -0.0193969 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0189829 |
| AZIN1 | antizyme inhibitor 1 | -0.0189113 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0188009 |
| HELZ | helicase with zinc finger | -0.0182755 |
| PHF21A | PHD finger protein 21A | -0.0181778 |
| ANK2 | ankyrin 2, neuronal | -0.0180852 |
