| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Uridine perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Uridine_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.171667 |
| B2M | beta-2-microglobulin | 0.123945 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0808389 |
| EZR | ezrin | 0.0740864 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0720064 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0679499 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0640796 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0632517 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0584488 |
| CALR | calreticulin | 0.0581403 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0524081 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0507344 |
| GOLGB1 | golgin B1 | 0.0497972 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0490505 |
| RRBP1 | ribosome binding protein 1 | 0.0485168 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0478794 |
| DSPP | dentin sialophosphoprotein | 0.0457903 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.0449212 |
| CANX | calnexin | 0.0408307 |
| SQSTM1 | sequestosome 1 | 0.0401294 |
| ANXA1 | annexin A1 | 0.0397121 |
| GOLGA4 | golgin A4 | 0.0393403 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0388006 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0375635 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0374277 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0361408 |
| ADM | adrenomedullin | 0.0343896 |
| IRF1 | interferon regulatory factor 1 | 0.0342887 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0337928 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0314468 |
| CALU | calumenin | 0.0311548 |
| LMO7 | LIM domain 7 | 0.0309886 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0309577 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0305653 |
| MORF4L2 | mortality factor 4 like 2 | 0.0297545 |
| GOLGA2 | golgin A2 | 0.028382 |
| PKM | pyruvate kinase, muscle | 0.0283437 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0282401 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0279858 |
| HYOU1 | hypoxia up-regulated 1 | 0.0275111 |
| HDLBP | high density lipoprotein binding protein | 0.0274985 |
| JUN | jun proto-oncogene | 0.0273849 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0271033 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0267446 |
| COG6 | component of oligomeric golgi complex 6 | 0.0264408 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | 0.0263089 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0260624 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0255738 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0252015 |
| CDHR2 | cadherin-related family member 2 | 0.0248236 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.024294 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0242209 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | 0.0241687 |
| DIS3 | DIS3 exosome endoribonuclease and 3'-5' exoribonuclease | 0.0237106 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0234737 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0233098 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0230607 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0228245 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0228002 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0226873 |
| SUCO | SUN domain containing ossification factor | 0.0224565 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0222625 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | 0.0217206 |
| PMM2 | phosphomannomutase 2 | 0.0215244 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0214636 |
| SFTPA2 | surfactant protein A2 | 0.0213568 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0212676 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0212209 |
| RPL3 | ribosomal protein L3 | 0.0211772 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0211087 |
| TPI1 | triosephosphate isomerase 1 | 0.0210602 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | 0.0207385 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0206884 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0206717 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0205825 |
| RFX2 | regulatory factor X, 2 (influences HLA class II expression) | 0.02053 |
| SRP54 | signal recognition particle 54kDa | 0.0202017 |
| UGDH | UDP-glucose 6-dehydrogenase | 0.0199842 |
| TMF1 | TATA element modulatory factor 1 | 0.0199645 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0199523 |
| ENO1 | enolase 1, (alpha) | 0.0199296 |
| PER2 | period circadian clock 2 | 0.0193352 |
| COPA | coatomer protein complex, subunit alpha | 0.0193207 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0192341 |
| BRD2 | bromodomain containing 2 | 0.0189734 |
| TFG | TRK-fused gene | 0.0188274 |
| FNIP1 | folliculin interacting protein 1 | 0.0187995 |
| NDRG1 | N-myc downstream regulated 1 | 0.0187172 |
| SPTY2D1 | SPT2, Suppressor of Ty, domain containing 1 (S. cerevisiae) | 0.0185498 |
| WEE1 | WEE1 G2 checkpoint kinase | 0.0184976 |
| SEC24D | SEC24 family member D | 0.0182376 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0180831 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | 0.0180585 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | 0.017912 |
| ACIN1 | apoptotic chromatin condensation inducer 1 | 0.0178691 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.0178583 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0177999 |
| IER2 | immediate early response 2 | 0.0176854 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | 0.0176566 |
| GOLGA3 | golgin A3 | 0.0174898 |
| Symbol | Name | Standardized Value |
|---|---|---|
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.109226 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | -0.082078 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0780953 |
| VCL | vinculin | -0.0649548 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0616869 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0610304 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0576832 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0570313 |
| STS | steroid sulfatase (microsomal), isozyme S | -0.0553412 |
| ERBIN | erbb2 interacting protein | -0.0527852 |
| PLSCR1 | phospholipid scramblase 1 | -0.0521796 |
| NCKAP5 | NCK-associated protein 5 | -0.0513501 |
| RAD51B | RAD51 paralog B | -0.0505801 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0505506 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.0497534 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0460137 |
| MX1 | MX dynamin-like GTPase 1 | -0.0459163 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0457598 |
| SP100 | SP100 nuclear antigen | -0.0443643 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.0429018 |
| XAF1 | XIAP associated factor 1 | -0.0427553 |
| ATP11A | ATPase, class VI, type 11A | -0.0425054 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0414611 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0411059 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0402297 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0397189 |
| ANKRD10 | ankyrin repeat domain 10 | -0.039477 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0386499 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0384619 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0378365 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0371551 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | -0.0363979 |
| NF1 | neurofibromin 1 | -0.0361364 |
| MX2 | MX dynamin-like GTPase 2 | -0.036102 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0357697 |
| RNF213 | ring finger protein 213 | -0.0354686 |
| FOXP1 | forkhead box P1 | -0.0345261 |
| BICRAL | BICRA like chromatin remodeling complex associated protein | -0.034202 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0340409 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0340276 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0338722 |
| ETV6 | ets variant 6 | -0.0337457 |
| PRKCA | protein kinase C, alpha | -0.0332557 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0329731 |
| TMEM62 | transmembrane protein 62 | -0.0324011 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.0321841 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0321059 |
| FMN1 | formin 1 | -0.0314329 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0309513 |
| MSI2 | musashi RNA-binding protein 2 | -0.030929 |
| NPSR1 | neuropeptide S receptor 1 | -0.030525 |
| STK24 | serine/threonine kinase 24 | -0.0304 |
| ATP10B | ATPase, class V, type 10B | -0.0301077 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0296877 |
| SPATA13 | spermatogenesis associated 13 | -0.0296873 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0294654 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0290855 |
| RUNX1 | runt-related transcription factor 1 | -0.0287476 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -0.0282702 |
| YAP1 | Yes-associated protein 1 | -0.027965 |
| RNF43 | ring finger protein 43 | -0.0279118 |
| ANXA2 | annexin A2 | -0.0277608 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0277134 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0275935 |
| DGKH | diacylglycerol kinase, eta | -0.0272178 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.027125 |
| SSH2 | slingshot protein phosphatase 2 | -0.0269716 |
| SERINC5 | serine incorporator 5 | -0.0268913 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0264187 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0262338 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0258913 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0257627 |
| SMAD3 | SMAD family member 3 | -0.0257495 |
| PCED1B | PC-esterase domain containing 1B | -0.0250588 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.0248529 |
| RIGI | RNA sensor RIG-I | -0.0247961 |
| EXOC4 | exocyst complex component 4 | -0.0247861 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0247829 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0241233 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.0240732 |
| ITGA6 | integrin, alpha 6 | -0.0238449 |
| PMP22 | peripheral myelin protein 22 | -0.0236229 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0235114 |
| TNS4 | tensin 4 | -0.0231041 |
| LYZ | lysozyme | -0.0229468 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0228237 |
| EXT1 | exostosin glycosyltransferase 1 | -0.022788 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0226969 |
| SMYD3 | SET and MYND domain containing 3 | -0.0226373 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0223285 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0222771 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0222367 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.0222157 |
| SPIDR | scaffolding protein involved in DNA repair | -0.0218264 |
| PRKCE | protein kinase C, epsilon | -0.0217772 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0213558 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0212879 |
| PERP | PERP, TP53 apoptosis effector | -0.0212807 |
| FARP1 | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) | -0.0212642 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.021229 |
