| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Uridine perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Uridine_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.266904 |
| FN1 | fibronectin 1 | 0.111624 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0670282 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0641783 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0557761 |
| PLEC | plectin | 0.0521726 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.045592 |
| POSTN | periostin, osteoblast specific factor | 0.0426538 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0390956 |
| ATP13A3 | ATPase type 13A3 | 0.0372571 |
| TMSB4X | thymosin beta 4, X-linked | 0.0370813 |
| RPL3 | ribosomal protein L3 | 0.0358109 |
| STC1 | stanniocalcin 1 | 0.0355551 |
| MSN | moesin | 0.0353223 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0345342 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0339808 |
| CALR | calreticulin | 0.0337737 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0334305 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0333889 |
| APP | amyloid beta (A4) precursor protein | 0.0316709 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0307913 |
| COL4A1 | collagen, type IV, alpha 1 | 0.0301955 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0292647 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0271483 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0259882 |
| RPS2 | ribosomal protein S2 | 0.0254495 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0243693 |
| FLNA | filamin A, alpha | 0.0243528 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0234769 |
| CLIC4 | chloride intracellular channel 4 | 0.0233096 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0232822 |
| RASA2 | RAS p21 protein activator 2 | 0.0225504 |
| CSF1 | colony stimulating factor 1 (macrophage) | 0.0219975 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0201395 |
| SMAD3 | SMAD family member 3 | 0.0200292 |
| B2M | beta-2-microglobulin | 0.0197917 |
| DSPP | dentin sialophosphoprotein | 0.0197607 |
| HYOU1 | hypoxia up-regulated 1 | 0.0188195 |
| CALU | calumenin | 0.0185921 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0181682 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.017956 |
| IGFBP7 | insulin-like growth factor binding protein 7 | 0.0177701 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | 0.0175504 |
| LRRC59 | leucine rich repeat containing 59 | 0.0175215 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0173417 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0171786 |
| PKM | pyruvate kinase, muscle | 0.0165595 |
| BRD2 | bromodomain containing 2 | 0.0163039 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0162638 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0161695 |
| ARRDC3 | arrestin domain containing 3 | 0.016098 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0159991 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0158774 |
| SPAG9 | sperm associated antigen 9 | 0.0152122 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.015136 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0150164 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0149881 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0147359 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0143623 |
| TPM2 | tropomyosin 2 (beta) | 0.0142386 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0140159 |
| TPM3 | tropomyosin 3 | 0.0138652 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0138423 |
| SET | SET nuclear proto-oncogene | 0.0136652 |
| TLN1 | talin 1 | 0.0134969 |
| HMGB2 | high mobility group box 2 | 0.0134613 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0132646 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.013162 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0129717 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0129211 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0127477 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0126197 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0124492 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0124204 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0123039 |
| SDC4 | syndecan 4 | 0.0122709 |
| CPNE1 | copine I | 0.0122383 |
| FSTL1 | follistatin-like 1 | 0.0121468 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0121122 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0120795 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0120499 |
| DST | dystonin | 0.0119991 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0119974 |
| OS9 | osteosarcoma amplified 9, endoplasmic reticulum lectin | 0.0118064 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0117669 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0117667 |
| FAT1 | FAT atypical cadherin 1 | 0.0117464 |
| H1-4 | H1.4 linker histone, cluster member | 0.011712 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0116968 |
| TPI1 | triosephosphate isomerase 1 | 0.0116872 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.011605 |
| IGF2R | insulin-like growth factor 2 receptor | 0.0115253 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0115057 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0113756 |
| MCL1 | myeloid cell leukemia 1 | 0.0113508 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0111758 |
| TMF1 | TATA element modulatory factor 1 | 0.0111039 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0110886 |
| IER2 | immediate early response 2 | 0.0110732 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0109362 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | -0.321851 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.317441 |
| VIM | vimentin | -0.137769 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.130475 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.128678 |
| COL1A1 | collagen, type I, alpha 1 | -0.117903 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0892275 |
| CDH13 | cadherin 13 | -0.0810302 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0666257 |
| CADM1 | cell adhesion molecule 1 | -0.0664812 |
| IER3 | immediate early response 3 | -0.0630033 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0583604 |
| COL1A2 | collagen, type I, alpha 2 | -0.0557264 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0479223 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.047153 |
| TMSB10 | thymosin beta 10 | -0.0464458 |
| LOX | lysyl oxidase | -0.0423433 |
| CD44 | CD44 molecule (Indian blood group) | -0.0410784 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.0391101 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0390361 |
| FTL | ferritin, light polypeptide | -0.0369586 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0365366 |
| LOXL2 | lysyl oxidase-like 2 | -0.0361859 |
| TPM4 | tropomyosin 4 | -0.0356695 |
| EGFR | epidermal growth factor receptor | -0.0339193 |
| HLA-B | major histocompatibility complex, class I, B | -0.0333853 |
| MTDH | metadherin | -0.0325535 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0311617 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0310285 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0307785 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0301951 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0296448 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0288005 |
| PDE10A | phosphodiesterase 10A | -0.028659 |
| RPL35A | ribosomal protein L35a | -0.027962 |
| TMEM165 | transmembrane protein 165 | -0.0274882 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0266437 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0262087 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0254704 |
| ACTG1 | actin gamma 1 | -0.0254289 |
| RUNX1 | runt-related transcription factor 1 | -0.0242953 |
| UBC | ubiquitin C | -0.0241907 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0235117 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | -0.0235107 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0234975 |
| STC2 | stanniocalcin 2 | -0.0232014 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0229511 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0225111 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0223847 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0221733 |
| LMAN1 | lectin, mannose-binding, 1 | -0.022084 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0219953 |
| CA12 | carbonic anhydrase XII | -0.0212552 |
| VEGFA | vascular endothelial growth factor A | -0.0209572 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0209287 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0208594 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0207663 |
| COL5A1 | collagen, type V, alpha 1 | -0.0207493 |
| IL6 | interleukin 6 | -0.0201103 |
| NAV1 | neuron navigator 1 | -0.020059 |
| RPS6 | ribosomal protein S6 | -0.0198854 |
| S100A9 | S100 calcium binding protein A9 | -0.0197409 |
| CLMP | CXADR-like membrane protein | -0.0196016 |
| OSMR | oncostatin M receptor | -0.0191369 |
| RPS8 | ribosomal protein S8 | -0.0187756 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0186539 |
| FAM162A | family with sequence similarity 162, member A | -0.0185347 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0184561 |
| EHD2 | EH-domain containing 2 | -0.0184558 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.01835 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0182775 |
| GLIS3 | GLIS family zinc finger 3 | -0.0182122 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0181841 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0181772 |
| RPL28 | ribosomal protein L28 | -0.0179608 |
| BNC2 | basonuclin 2 | -0.0179553 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | -0.0177658 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.017734 |
| KIF13A | kinesin family member 13A | -0.0177091 |
| CMIP | c-Maf inducing protein | -0.0176566 |
| FGFR1 | fibroblast growth factor receptor 1 | -0.0176052 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.0175965 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0174262 |
| FOXP1 | forkhead box P1 | -0.0172357 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0172018 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0170863 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.017073 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0166522 |
| ATXN1 | ataxin 1 | -0.016539 |
| S100A10 | S100 calcium binding protein A10 | -0.0161503 |
| TRAM1 | translocation associated membrane protein 1 | -0.0160385 |
| DPYSL2 | dihydropyrimidinase-like 2 | -0.0160258 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.015958 |
| VDAC1 | voltage-dependent anion channel 1 | -0.015957 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0158309 |
| ZNF395 | zinc finger protein 395 | -0.015827 |
| S100A6 | S100 calcium binding protein A6 | -0.0157703 |
| CCDC80 | coiled-coil domain containing 80 | -0.0157414 |
| MYADM | myeloid-associated differentiation marker | -0.015706 |
| FAM13A | family with sequence similarity 13, member A | -0.0156782 |
