| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Uridine perturbation in KATO III cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Uridine_KATO III drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FGFR2 | fibroblast growth factor receptor 2 | 0.313269 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.193027 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.153525 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.133989 |
| TMSB4X | thymosin beta 4, X-linked | 0.113893 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.107013 |
| KRT18 | keratin 18, type I | 0.103693 |
| DSPP | dentin sialophosphoprotein | 0.102437 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.0972253 |
| LMO7 | LIM domain 7 | 0.095979 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0871122 |
| HYOU1 | hypoxia up-regulated 1 | 0.0864504 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.070098 |
| EZR | ezrin | 0.0685062 |
| PLEC | plectin | 0.0658468 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0650585 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0641058 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0635303 |
| CALR | calreticulin | 0.0610042 |
| PGK1 | phosphoglycerate kinase 1 | 0.0583215 |
| ANXA1 | annexin A1 | 0.0577205 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0575739 |
| B2M | beta-2-microglobulin | 0.0571189 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.056833 |
| EMP1 | epithelial membrane protein 1 | 0.0513577 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0503602 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0500636 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0491755 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0483487 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0480966 |
| FAT1 | FAT atypical cadherin 1 | 0.0480092 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0475899 |
| AHNAK | AHNAK nucleoprotein | 0.0473428 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | 0.0432881 |
| KRT8 | keratin 8, type II | 0.042088 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.041143 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0395568 |
| CPNE1 | copine I | 0.0395015 |
| TPI1 | triosephosphate isomerase 1 | 0.0388003 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0387308 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0384749 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0380746 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0370704 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0369025 |
| SET | SET nuclear proto-oncogene | 0.0354637 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0349803 |
| RAD21 | RAD21 homolog (S. pombe) | 0.034748 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0345481 |
| SRPRA | SRP receptor subunit alpha | 0.0339628 |
| MYOF | myoferlin | 0.0324591 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0321198 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0304634 |
| ANLN | anillin, actin binding protein | 0.0304415 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | 0.0296485 |
| RNF213 | ring finger protein 213 | 0.0295596 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0293254 |
| LRRC59 | leucine rich repeat containing 59 | 0.0292587 |
| HMGB2 | high mobility group box 2 | 0.0291418 |
| DST | dystonin | 0.0290642 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0288147 |
| TMF1 | TATA element modulatory factor 1 | 0.0287318 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0285623 |
| SUN1 | Sad1 and UNC84 domain containing 1 | 0.0285198 |
| SMC1A | structural maintenance of chromosomes 1A | 0.0284799 |
| RPS2 | ribosomal protein S2 | 0.028467 |
| CTTN | cortactin | 0.0278891 |
| RPL3 | ribosomal protein L3 | 0.0276569 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0274987 |
| RRBP1 | ribosome binding protein 1 | 0.0270685 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0268297 |
| SSR1 | signal sequence receptor, alpha | 0.0265548 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0264807 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0256304 |
| GOLGA3 | golgin A3 | 0.0255223 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0253409 |
| LAMB3 | laminin, beta 3 | 0.025146 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0249279 |
| PRSS23 | protease, serine, 23 | 0.0249063 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0248928 |
| NARS1 | asparaginyl-tRNA synthetase 1 | 0.0248379 |
| PPL | periplakin | 0.0244156 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0241831 |
| KRT17 | keratin 17, type I | 0.0241192 |
| APP | amyloid beta (A4) precursor protein | 0.023348 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0230917 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0230195 |
| EPCAM | epithelial cell adhesion molecule | 0.0228382 |
| ASPH | aspartate beta-hydroxylase | 0.0228092 |
| TPM3 | tropomyosin 3 | 0.0227556 |
| CALCOCO2 | calcium binding and coiled-coil domain 2 | 0.0225944 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0224076 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0223724 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.0223609 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0222995 |
| RPS3 | ribosomal protein S3 | 0.0219585 |
| XPOT | exportin, tRNA | 0.0219397 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0219275 |
| HDLBP | high density lipoprotein binding protein | 0.0217005 |
| MYH14 | myosin, heavy chain 14, non-muscle | 0.0216215 |
| AHR | aryl hydrocarbon receptor | 0.0215701 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NPSR1 | neuropeptide S receptor 1 | -0.163356 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.145115 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.107606 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.102897 |
| POTEF | POTE ankyrin domain family, member F | -0.0753056 |
| TMSB10 | thymosin beta 10 | -0.0732523 |
| ANXA2 | annexin A2 | -0.0689331 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0661706 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.064935 |
| HMGA1 | high mobility group AT-hook 1 | -0.0589965 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0564207 |
| NDRG1 | N-myc downstream regulated 1 | -0.0561105 |
| RAB7A | RAB7A, member RAS oncogene family | -0.056036 |
| BCL2L1 | BCL2-like 1 | -0.0543991 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0518964 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0514679 |
| RPS6 | ribosomal protein S6 | -0.0510115 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0442045 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0434782 |
| SH3RF1 | SH3 domain containing ring finger 1 | -0.0422972 |
| RPL35A | ribosomal protein L35a | -0.0420546 |
| JUP | junction plakoglobin | -0.0417551 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0408742 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0376214 |
| WWC1 | WW and C2 domain containing 1 | -0.0375345 |
| ITGB4 | integrin, beta 4 | -0.0373917 |
| LCN2 | lipocalin 2 | -0.0363268 |
| ATXN1 | ataxin 1 | -0.0343517 |
| RPLP1 | ribosomal protein, large, P1 | -0.0341115 |
| PRSS3 | protease, serine, 3 | -0.0338194 |
| RPS25 | ribosomal protein S25 | -0.0329567 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | -0.0326437 |
| GPX2 | glutathione peroxidase 2 | -0.0303053 |
| CLDN4 | claudin 4 | -0.0298286 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0298197 |
| RPS24 | ribosomal protein S24 | -0.0297928 |
| AVL9 | AVL9 homolog (S. cerevisiase) | -0.029279 |
| FGD4 | FYVE, RhoGEF and PH domain containing 4 | -0.0284991 |
| RPS21 | ribosomal protein S21 | -0.0284128 |
| PPARG | peroxisome proliferator-activated receptor gamma | -0.0282825 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0282787 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.027514 |
| HMGB1 | high mobility group box 1 | -0.0266813 |
| DEK | DEK proto-oncogene | -0.0265223 |
| TMEM123 | transmembrane protein 123 | -0.0262502 |
| RPL9 | ribosomal protein L9 | -0.0260724 |
| ATF5 | activating transcription factor 5 | -0.0259787 |
| SLC9A3R1 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 | -0.0255036 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | -0.0253987 |
| DIAPH2 | diaphanous-related formin 2 | -0.0252015 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.025002 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0248259 |
| RPL28 | ribosomal protein L28 | -0.0247563 |
| YAP1 | Yes-associated protein 1 | -0.0247479 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | -0.0247384 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0245358 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0244512 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0244409 |
| VEGFA | vascular endothelial growth factor A | -0.0244247 |
| PFN1 | profilin 1 | -0.0242002 |
| TTYH3 | tweety family member 3 | -0.0241651 |
| FASN | fatty acid synthase | -0.024113 |
| PLSCR1 | phospholipid scramblase 1 | -0.0239447 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0236026 |
| UBE2R2 | ubiquitin-conjugating enzyme E2R 2 | -0.0233456 |
| PIAS1 | protein inhibitor of activated STAT, 1 | -0.022992 |
| TNRC18 | trinucleotide repeat containing 18 | -0.0226775 |
| ZNF292 | zinc finger protein 292 | -0.0226034 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0225451 |
| S100A6 | S100 calcium binding protein A6 | -0.0222568 |
| LAMA5 | laminin, alpha 5 | -0.0220811 |
| MUC1 | mucin 1, cell surface associated | -0.0218872 |
| ANXA11 | annexin A11 | -0.0217926 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0215742 |
| CCNL1 | cyclin L1 | -0.0215041 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0213138 |
| RPL30 | ribosomal protein L30 | -0.0211973 |
| CBX3 | chromobox homolog 3 | -0.0211099 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0210943 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0208758 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | -0.0208067 |
| PTEN | phosphatase and tensin homolog | -0.020793 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0205759 |
| HLA-B | major histocompatibility complex, class I, B | -0.0205725 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0205224 |
| TAPBP | TAP binding protein (tapasin) | -0.0204209 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | -0.0203998 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.0203257 |
| RPS16 | ribosomal protein S16 | -0.0201456 |
| WWOX | WW domain containing oxidoreductase | -0.0201229 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0200897 |
| TNS4 | tensin 4 | -0.0196972 |
| CHKA | choline kinase alpha | -0.0196544 |
| PRKCA | protein kinase C, alpha | -0.0196452 |
| TRA2B | transformer 2 beta homolog (Drosophila) | -0.0194809 |
| LRP5 | low density lipoprotein receptor-related protein 5 | -0.0194414 |
| FOSL1 | FOS-like antigen 1 | -0.0194133 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.019396 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0190158 |
| ZNF609 | zinc finger protein 609 | -0.0189671 |
