| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Uridine perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Uridine_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ASPH | aspartate beta-hydroxylase | 0.141106 |
| LAMC2 | laminin, gamma 2 | 0.130426 |
| TXNRD1 | thioredoxin reductase 1 | 0.115471 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.10927 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0919802 |
| PTMA | prothymosin, alpha | 0.0892801 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0841948 |
| LMO7 | LIM domain 7 | 0.0792297 |
| PKM | pyruvate kinase, muscle | 0.0784319 |
| DSPP | dentin sialophosphoprotein | 0.077861 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.074825 |
| LAMB3 | laminin, beta 3 | 0.0731248 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0701745 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.069432 |
| TMSB10 | thymosin beta 10 | 0.0693402 |
| ENO1 | enolase 1, (alpha) | 0.068758 |
| PLEC | plectin | 0.0657665 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0657612 |
| FAM13A | family with sequence similarity 13, member A | 0.064284 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0609714 |
| PGK1 | phosphoglycerate kinase 1 | 0.0593176 |
| MT2A | metallothionein 2A | 0.0570682 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0563317 |
| STC1 | stanniocalcin 1 | 0.056184 |
| ACTG1 | actin gamma 1 | 0.0537648 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.053355 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0510107 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0507637 |
| RPS3 | ribosomal protein S3 | 0.0493727 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | 0.049135 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0483579 |
| AHNAK | AHNAK nucleoprotein | 0.0473477 |
| KRT18 | keratin 18, type I | 0.0461131 |
| MKI67 | marker of proliferation Ki-67 | 0.0458563 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0450408 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0445975 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0442551 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | 0.0441541 |
| LDHA | lactate dehydrogenase A | 0.0441496 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.043338 |
| MCL1 | myeloid cell leukemia 1 | 0.0431595 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0427909 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.042348 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0420278 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.041051 |
| HYOU1 | hypoxia up-regulated 1 | 0.0407558 |
| SMAD3 | SMAD family member 3 | 0.0393647 |
| B2M | beta-2-microglobulin | 0.0393245 |
| H1-0 | H1.0 linker histone | 0.0389506 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.038352 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | 0.0378851 |
| RAB10 | RAB10, member RAS oncogene family | 0.0369013 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0364701 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0361315 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0355156 |
| TPD52 | tumor protein D52 | 0.0354145 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0354086 |
| TES | testin LIM domain protein | 0.0351807 |
| SLTM | SAFB-like, transcription modulator | 0.0346392 |
| LAMA4 | laminin, alpha 4 | 0.0346246 |
| CANX | calnexin | 0.034615 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0346086 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0337563 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0336969 |
| APP | amyloid beta (A4) precursor protein | 0.033576 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0326955 |
| TPI1 | triosephosphate isomerase 1 | 0.0323119 |
| S100A10 | S100 calcium binding protein A10 | 0.032222 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0321972 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0319377 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0319367 |
| HDLBP | high density lipoprotein binding protein | 0.0319039 |
| GRAMD1B | GRAM domain containing 1B | 0.031876 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0315149 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0314236 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0314128 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0314013 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.0310917 |
| SEC61G | Sec61 gamma subunit | 0.0309707 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0308687 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0308439 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | 0.0306452 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0304204 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0303195 |
| PYGL | phosphorylase, glycogen, liver | 0.0303016 |
| FTL | ferritin, light polypeptide | 0.0301319 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0300928 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0299134 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0294642 |
| RPL4 | ribosomal protein L4 | 0.0293089 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0291996 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.0290653 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.028859 |
| EGFR | epidermal growth factor receptor | 0.0285075 |
| MSN | moesin | 0.0282688 |
| UBC | ubiquitin C | 0.0281274 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0281163 |
| RPL3 | ribosomal protein L3 | 0.0277672 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0277009 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0275606 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | -0.0743207 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0678336 |
| NDRG1 | N-myc downstream regulated 1 | -0.058707 |
| EGR1 | early growth response 1 | -0.0462053 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0372056 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0337507 |
| TMEM165 | transmembrane protein 165 | -0.0334507 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0283688 |
| CCNL1 | cyclin L1 | -0.0204634 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0192629 |
| PTEN | phosphatase and tensin homolog | -0.0173605 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0157347 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0149279 |
| CPEB2 | cytoplasmic polyadenylation element binding protein 2 | -0.0149179 |
| MGAT4C | MGAT4 family, member C | -0.0133267 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0127548 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0121764 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0120778 |
| LAMA5 | laminin, alpha 5 | -0.0119047 |
| DHFR | dihydrofolate reductase | -0.0114445 |
| METTL15 | methyltransferase like 15 | -0.0111582 |
| ZBTB25 | zinc finger and BTB domain containing 25 | -0.0105469 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | -0.0102943 |
| MEF2D | myocyte enhancer factor 2D | -0.0102684 |
| TRAPPC9 | trafficking protein particle complex 9 | -0.010054 |
| SEC24D | SEC24 family member D | -0.0100001 |
| TMEM39A | transmembrane protein 39A | -0.00993075 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | -0.00985818 |
| FNIP1 | folliculin interacting protein 1 | -0.00946311 |
| NDEL1 | nudE neurodevelopment protein 1-like 1 | -0.00941026 |
| ATN1 | atrophin 1 | -0.00933233 |
| HCFC1 | host cell factor C1 | -0.00931292 |
| TAPBP | TAP binding protein (tapasin) | -0.00921015 |
| TMEM161B | transmembrane protein 161B | -0.00904914 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | -0.00895447 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.00884227 |
| TXNDC11 | thioredoxin domain containing 11 | -0.00879046 |
| FOSL1 | FOS-like antigen 1 | -0.00859566 |
| EYA2 | EYA transcriptional coactivator and phosphatase 2 | -0.00856123 |
| RAB7A | RAB7A, member RAS oncogene family | -0.00837232 |
| JUP | junction plakoglobin | -0.00836904 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.00832432 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.00816639 |
| SHOC2 | soc-2 suppressor of clear homolog (C. elegans) | -0.00809091 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.00795305 |
| CCNH | cyclin H | -0.007925 |
| RAB28 | RAB28, member RAS oncogene family | -0.00789707 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | -0.00789194 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | -0.00777904 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.00774313 |
| EP400 | E1A binding protein p400 | -0.00766976 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.00766348 |
| NABP1 | nucleic acid binding protein 1 | -0.0075289 |
| NUP98 | nucleoporin 98kDa | -0.00747468 |
| RNASEH2A | ribonuclease H2, subunit A | -0.00739723 |
| BCL9L | B-cell CLL/lymphoma 9-like | -0.00729437 |
| NPC1 | Niemann-Pick disease, type C1 | -0.00726447 |
| AGRN | agrin | -0.00724459 |
| NUP214 | nucleoporin 214kDa | -0.00718416 |
| NHSL3 | NHS like 3 | -0.00715257 |
| CYSTM1 | cysteine-rich transmembrane module containing 1 | -0.00713558 |
| FBRS | fibrosin | -0.00710307 |
| RAP2B | RAP2B, member of RAS oncogene family | -0.00692801 |
| MDM4 | MDM4, p53 regulator | -0.00687568 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.00664961 |
| FBXO33 | F-box protein 33 | -0.00663794 |
| CDKL5 | cyclin-dependent kinase-like 5 | -0.0066305 |
| BTRC | beta-transducin repeat containing E3 ubiquitin protein ligase | -0.00662377 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.00658374 |
| ZBTB44 | zinc finger and BTB domain containing 44 | -0.0065725 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.00647897 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.00646127 |
| CFDP1 | craniofacial development protein 1 | -0.00643304 |
| UBE4A | ubiquitination factor E4A | -0.00640918 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.00637775 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | -0.00635795 |
| IRF9 | interferon regulatory factor 9 | -0.00629756 |
| ELK4 | ELK4, ETS-domain protein (SRF accessory protein 1) | -0.00627591 |
| OTUD5 | OTU deubiquitinase 5 | -0.0061342 |
| CAST | calpastatin | -0.0061247 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.00611182 |
| SPCS2 | signal peptidase complex subunit 2 homolog (S. cerevisiae) | -0.00606573 |
| GTPBP1 | GTP binding protein 1 | -0.00602459 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.00598885 |
| PMP22 | peripheral myelin protein 22 | -0.00598569 |
| CCNK | cyclin K | -0.00598264 |
| CD68 | CD68 molecule | -0.00597775 |
| ATG13 | autophagy related 13 | -0.00596061 |
| FOSL2 | FOS-like antigen 2 | -0.00588256 |
| DGCR2 | DiGeorge syndrome critical region gene 2 | -0.00583717 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.00578925 |
| SEC22A | SEC22 vesicle trafficking protein homolog A (S. cerevisiae) | -0.0057538 |
| CDKN2A | cyclin-dependent kinase inhibitor 2A | -0.00573531 |
| SETD1B | SET domain containing 1B | -0.00570559 |
| PRKCH | protein kinase C, eta | -0.00568093 |
| BLTP1 | bridge-like lipid transfer protein family member 1 | -0.00564799 |
| TRIB1 | tribbles pseudokinase 1 | -0.00559058 |
| GPATCH2L | G patch domain containing 2-like | -0.0055898 |
| RNLS | renalase, FAD-dependent amine oxidase | -0.00558518 |
| CLDN4 | claudin 4 | -0.00557503 |
